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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
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Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 21 to 23 of 23 (0.378 seconds)| 21 |
Matematické metody pro zpracování obrazu v biologických pozorováních / Mathematical Methods for Image Processing in Biological ObservationsZikmund, Tomáš January 2014 (has links)
The dissertation deals with the image processing in digital holographic microscopy and X-ray computed tomography. The focus of the work lies in the proposal of data processing techniques to meet the needs of the biological experiments. Transmitted light holographic microscopy is particularly used for quantitative phase imaging of transparent microscopic objects such as living cells. The phase images are affected by the phase aberrations that make the analysis particularly difficult. Here, we present a novel algorithm for dynamical processing of living cells phase images in a time-lapse sequence. The algorithm compensates for the deformation of a phase image using weighted least squares surface fitting. Moreover, it identifies and segments the individual cells in the phase image. This property of the algorithm is important for real-time cell quantitative phase imaging and instantaneous control of the course of the experiment. The efficiency of the propounded algorithm is demonstrated on images of rat fibrosarcoma cells using an off-axis holographic microscope. High resolution X-ray computed tomography is increasingly used technique for the study of the small rodent bones micro-structure. In this part of the work, the trabecular and cortical bone morphology is assessed in the distal half of rat femur. We developed new method for mapping the cortical position and dimensions from a central longitudinal axis with one degree angular resolution. This method was used to examine differences between experimental groups. The bone position in tomographic slices is aligned before the mapping using the propound standardization procedure. The activity of remodelling process of the long bone is studied on the system of cortical canals.
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Développement, étude expérimentale et visualisation par holographie digitale de mini-séparateurs fluidiques (STEP-SPLITT) en vue de la séparation d'objets de taille micrométrique. / Development, experimental study and visualization by digital holography of mini fluidic separators (STEP-SPLITT) in order to separate micron-size species.Callens, Natacha N 22 December 2005 (has links)
Cette thèse expérimentale s’inscrit dans le domaine des sciences séparatives et se base sur la technique de SPLITT (SPLIT-flow Thin fractionation). Son objectif consiste en l’étude des mécanismes qui sont à l’origine de la séparation, en continu et sans membrane, d’objets de taille micrométrique dans des mini-séparateurs fluidiques (Step-SPLITT). Les expériences menées, en laboratoire et lors de vols paraboliques, ont révélé le couplage complexe comme l’influence des effets hydrodynamiques et du champ gravitationnel sur la migration transverse des espèces en écoulement. Des visualisations tridimensionnelles par holographie digitale ont corroboré nos résultats et dévoilé des comportements inattendus. Les capacités séparatives des Step-SPLITT ont rendu possible l’analyse et la séparation d’objets biologiques et biomimétiques. Enfin, cette étude complétée par une modélisation tridimensionnelle de l’écoulement nous a permis de mettre au point un nouveau prototype de séparateur.
This experimental thesis belongs to the field of separative sciences and is based on the SPLITT technique (SPLIT-flow Thin fractionation). The objective is to study the mechanisms that are at the origin of continuous and membraneless separation of micron-size species in mini fluidic separators (Step-SPLITT). Experiments undertaken in laboratory and during parabolic flights revealed the complex coupling of the hydrodynamic effects and the gravitational field influencing the transverse migration of the flowing species. Three-dimensional visualizations performed by digital holography confirmed our results and disclosed unexpected behaviours. The separation capacities of Step-SPLITT made the analysis and the separation of biological and biomimetic species possible. In addition this study in conjunction with a three-dimensional flow modelling enabled us to develop a new prototype of separator.
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Développement, étude expérimentale et visualisation par holographie digitale de mini-séparateurs fluidiques (STEP-SPLITT) en vue de la séparation d'objets de taille micrométrique / Development, experimental study and visualization by digital holography of mini fluidic separators (STEP-SPLITT) in order to separate micron-size speciesCallens, Natacha 22 December 2005 (has links)
Cette thèse expérimentale s’inscrit dans le domaine des sciences séparatives et se base sur la technique de SPLITT (SPLIT-flow Thin fractionation). Son objectif consiste en l’étude des mécanismes qui sont à l’origine de la séparation, en continu et sans membrane, d’objets de taille micrométrique dans des mini-séparateurs fluidiques (Step-SPLITT). Les expériences menées, en laboratoire et lors de vols paraboliques, ont révélé le couplage complexe comme l’influence des effets hydrodynamiques et du champ gravitationnel sur la migration transverse des espèces en écoulement. Des visualisations tridimensionnelles par holographie digitale ont corroboré nos résultats et dévoilé des comportements inattendus. Les capacités séparatives des Step-SPLITT ont rendu possible l’analyse et la séparation d’objets biologiques et biomimétiques. Enfin, cette étude complétée par une modélisation tridimensionnelle de l’écoulement nous a permis de mettre au point un nouveau prototype de séparateur.<p><p>This experimental thesis belongs to the field of separative sciences and is based on the SPLITT technique (SPLIT-flow Thin fractionation). The objective is to study the mechanisms that are at the origin of continuous and membraneless separation of micron-size species in mini fluidic separators (Step-SPLITT). Experiments undertaken in laboratory and during parabolic flights revealed the complex coupling of the hydrodynamic effects and the gravitational field influencing the transverse migration of the flowing species. Three-dimensional visualizations performed by digital holography confirmed our results and disclosed unexpected behaviours. The separation capacities of Step-SPLITT made the analysis and the separation of biological and biomimetic species possible. In addition this study in conjunction with a three-dimensional flow modelling enabled us to develop a new prototype of separator. / Doctorat en sciences appliquées / info:eu-repo/semantics/nonPublished
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