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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
81

Optogenetic Inhibition of the mPFC During Delay Discounting

White, Shelby M. 05 1900 (has links)
Indiana University-Purdue University Indianapolis (IUPUI) / Impulsivity, or the tendency to act prematurely without foresight, has been linked to a diverse range of pathological conditions. Foresight refers to the ability to envision future rewards and events (i.e. prospectively sample) and has been associated with decreased impulsivity. One form of impulsivity is measured by the ability to delay gratification and is often studied in the framework of Delay Discounting (DD). DD provides the means to study impulsivity in a number of pathological conditions. However, whether impulsivity precedes the development of pathological states or results from the pathological state itself is not fully understood. This necessitates an understanding of neurobiological mechanisms contributing to decision making in both non-impulsive as well as impulsive populations of individuals. Animal models allow invasive techniques to be used to dissect the neurocircuitry involved in decision making. Given that the decision-making process is an ongoing process rather than an isolated event, optogenetics provide the temporal and spatial specificity necessary for evaluating brain region specific contributions to decision making in DD. In the present study, optogenetics were used to assess the contribution of the medial Prefrontal Cortex (mPFC), a brain region involved in ‘goal-directed’ behavior, in the planning of future choices (i.e. prospective plans) and subsequent measures of impulsivity in an adjusting amount DD procedure. Optogenetic inhibition of mPFC was conducted in Wistar rats during different epochs of a DD task in order to assess how mPFC affects planning behavior in a population of rat not considered to be highly impulsive. Although no direct effects on planning behavior (e.g. consistency) were observed, inhibiting mPFC after a trial has been initiated and directly before a choice was made (Epoch 2) was observed to increase measures of impulsivity in comparison to days where no optogenetic manipulation occurred in a delay-specific manner. This suggests that mPFC differentially contributes to decision making at different delays. A pattern of associations between choice latency, impulsivity, and consistency began to emerge for inactivation occurring in Epoch 2, suggesting that mPFC contributes to some aspect of planning choices during this epoch. Moreover, these results indicate that mPFC is involved in decision making in Wistar Rats. Understanding the direct role that mPFC plays in promoting choices of delayed rewards provides a neurobiological target for treatment aimed at reducing impulsivity in the clinical population.
82

Some aspects of the deglaciation of the Indian House Lake area with particular reference to the former proglacial lakes.

Barnett, David Martin. January 1964 (has links)
No description available.
83

Glacial geomorphology and postglacial uplift between Deception Bay and Cape Weggs. 1967.

Rogerson, Robert J. (Robert James) January 1967 (has links)
No description available.
84

Disturbance dynamics in west central British Columbia: multi-century relationships of fire, western spruce budworm outbreaks and climate

Harvey, Jillian E. 01 May 2017 (has links)
Future climate changes will alter disturbance regimes worldwide with important implications for many ecological and social systems. In west central British Columbia, Canada, fire and insect disturbances have shaped the historic character of Douglas-fir (Pseudotsuga menziesii var. glauca Beissn. Franco) dominated forests. However, since AD 1900 fire suppression and other forest management practices have led to denser forests and conifer encroachment into grasslands. Considering climate changes in interior British Columbia are expected to result in warmer and drier conditions, understanding the influence of climate on forest disturbances is crucial for land managers tasked with both mitigating the effects of disturbance and promoting resilience in forest ecosystems. This research focused on developing multi-century, annually-resolved records of fire and western spruce budworm outbreaks to evaluate: the historic climate conditions related to these disturbances; the influence of grassland proximity on disturbance-climate relationships; and, whether western spruce budworm outbreaks were related to fire activity. At the landscape scale, a detailed study in the Churn Creek Protected Area revealed spatially variable stand structure and fire-climate relationships at a low elevation forest-grassland ecotone over the interval AD 1600 to 1900. This finding suggests the site was characterized by fires of mixed-severity dominated by frequent, low-severity, fires related to positive antecedent moisture conditions punctuated by widespread fires of moderate to high severity related to intervals of persistent drought. At the regional scale, the influence of interannual climate variability and large-scale patterns of climate variability (e.g. El Nino Southern Oscillation) was evaluated using new and existing records of fire history and multiple climate pattern reconstructions. Regional fire activity was shown to be significantly related to interannual climate variability, and no consistent patterns between regional fire years and the individual phases or phase combinations of large-scale patterns of climate variability were detected. The findings suggest that the spatial expression of large-scale climate patterns translates into weak and undetectable terrestrial effects related to fire activity in this region. The influence of grassland proximity on disturbance history was investigated using site-level and regional tree-ring reconstructions of western spruce budworm outbreaks and fire activity based on four sites adjacent to grasslands and four sites not adjacent to grasslands between AD 1600 and 1900 (fire) and AD 1600 and 2009 (western spruce budworm). Fires affecting grassland proximal sites were more frequent than fires occurring in forests not adjacent to grasslands, and the character of western spruce budworm outbreaks was generally consistent among all sites. Fire activity was related to both warm, dry and cool, wet conditions in the fire year and/or year(s) preceding the fire depending on proximity to grasslands, suggesting climate conditions associated with both fine fuel growth and drying are key determinants for fire activity. The initiation of western spruce budworm outbreaks was significantly related to drought and this relationship was enhanced at sites adjacent to grasslands. At the site-level and regional scale, no consistent association was found between the initiation of western spruce budworm outbreaks and fire years indicating the historic interaction between these disturbances is weak or non-existent. / Graduate
85

Optogenetic Inhibition of the mPFC During Delay Discounting

Shelby M White (6615890) 10 June 2019 (has links)
<p> <i>Impulsivity</i>, or the tendency to act prematurely without foresight, has been linked to a diverse range of pathological conditions. Foresight refers to the ability to envision future rewards and events (i.e. prospectively sample) and has been associated with decreased impulsivity. One form of impulsivity is measured by the ability to delay gratification and is often studied in the framework of Delay Discounting (DD). DD provides the means to study impulsivity in a number of pathological conditions. However, whether impulsivity precedes the development of pathological states or results from the pathological state itself is not fully understood. This necessitates an understanding of neurobiological mechanisms contributing to decision making in both non-impulsive as well as impulsive populations of individuals. </p> <p> Animal models allow invasive techniques to be used to dissect the neurocircuitry involved in decision making. Given that the decision-making process is an ongoing process rather than an isolated event, optogenetics provide the temporal and spatial specificity necessary for evaluating brain region specific contributions to decision making in DD. In the present study, optogenetics were used to assess the contribution of the medial Prefrontal Cortex (mPFC), a brain region involved in ‘goal-directed’ behavior, in the planning of future choices (i.e. prospective plans) and subsequent measures of impulsivity in an adjusting amount DD procedure. Optogenetic inhibition of mPFC was conducted in Wistar rats during different epochs of a DD task in order to assess how mPFC affects planning behavior in a population of rat not considered to be highly impulsive. Although no direct effects on planning behavior (e.g. consistency) were observed, inhibiting mPFC after a trial has been initiated and directly before a choice was made (Epoch 2) was observed to increase measures of impulsivity in comparison to days where no optogenetic manipulation occurred in a delay-specific manner. This suggests that mPFC differentially contributes to decision making at different delays. A pattern of associations between choice latency, impulsivity, and consistency began to emerge for inactivation occurring in Epoch 2, suggesting that mPFC contributes to some aspect of planning choices during this epoch. Moreover, these results indicate that mPFC is involved in decision making in Wistar Rats. Understanding the direct role that mPFC plays in promoting choices of delayed rewards provides a neurobiological target for treatment aimed at reducing impulsivity in the clinical population.</p>
86

Panquilma y Cieneguilla en la discusión arqueológica del Horizonte Tardío de la costa central

Marcone, Giancarlo, López-Hurtado, Enrique 10 April 2018 (has links)
Panquilma and Cieneguilla in the Archaeological Discussion of the Late Horizon in the Central CoastIn the context of the initial works at the archaeological site of Panquilma, the authors offer new data for the site together with a brief review of previous work in the Cieneguilla area, where the site is located. This review discusses the geography, the settlement pattern and the ethnohistory of this area with some preliminary concluding remarks. / Aprovechando los trabajos arqueológicos iniciales realizados en el sitio de Panquilma, los autores aportan algunos datos nuevos sobre el sitio y analizan los datos ya existentes para el área de Cieneguilla, lugar donde se encuentra este sitio. Esta rápida revisión intenta abarcar la geografía, el patrón de asentamiento y las fuentes etnohistóricas conocidas, así como ensayar algunas conclusiones preliminares.
87

Dynamics of the British Ice Sheet and prevailing hydrographic conditions for the last 175,000 years : an investigation of marine sediment core MD04-2822 from the Rockall Trough

Hibbert, Fiona Danielle January 2011 (has links)
This study presents a stratigraphic investigation of the marine sediment core MD04-2822 from the Rockall Trough (56° 50.54' N, 11° 22.96' W; 2344 m water depth). This core is currently the only available high resolution record for the calibration of Late Quaternary sedimentary sequences of the British (Hebridean) margin. It therefore offers an unprecedented archive of changing sedimentological and climatological conditions for the last 175,000 years. The high resolution, multi-proxy records have enabled surface and deep water conditions within the Rockall Trough to be reconstructed. In addition, the fluctuating nature of ice-rafted debris (IRD) inputs to the MD04-2822 site allows a first order attempt of BIS dynamics for the entirety of the last glacial period (i.e. from the demise of the last interglacial to the decay of the Devensian/Weichselian ice sheet) as well as the majority of the penultimate (Saalian/MIS 6) glaciation. Sediment core MD04-2822 is ideally located to capture the dynamics of the British Ice Sheet (BIS) via a continuous record of IRD and fine-grained terrigenous inputs. Fundamental to this is the construction of a robust chronology. This was achieved via: the correlation of the benthic δ¹⁸O record to a global δ¹⁸O stack (SPECMAP); the correlation of the surface proxies (% N. pachyderma (sinistral) and XRF Ca) to the Greenland δ¹⁸O and Antarctic methane ice core records; and radiocarbon dating. This chronology was validated using both radiocarbon dating and tephra horizons. An evaluation of the event stratigraphy approach used in the construction of the MD04-2822 chronology is presented. The marine record provides a valuable archive of past ice sheet dynamics as much terrestrial evidence is removed or obscured by subsequent ice sheet oscillations MD04-2822 provides the first evidence for the expansion of the BIS onto the Hebridean Margin during MIS6 (thereby confirming previous long-range seismic correlations). The continuous sedimentation at MD04-2822 enabled the first insights into the early dynamics of the last BIS. Increases in IRD and fine grained terrigenous material delivered to the MD04-2822 at ca. 72 kyr represent the first significant delivery of material from the BIS across the continental shelf to the core site. The BIS would therefore have attained a marine calving margin by this time. A multi-proxy investigation of provenance was undertaken, however unequivocal provenance determinations remain problematic. The location of the core suggest the proximal BIS as the most likely source of terrigenous inputs. The expanded nature of the MD04-2822 sediments during the penultimate deglacial (Termination II) provides the first details of BIS dynamics for this period: the interplay of large inputs of freshwater from the decay of the Saalian (MIS 6) ice sheets (including the BIS) upon the surface and deep water circulation of the North Atlantic is investigated. In addition, sub-orbital climatic variability is documented at this location throughout the last interglacial (MIS 5e) and appears to be an intrinsic feature of both the N.E. Atlantic surface and deep water circulation of the last 175 kyr.
88

Next Generation Wideband Antenna Arrays for Communications and Radio Astrophysics

Kolitsidas, Christos January 2017 (has links)
Wideband, wide-scan antenna arrays are a promising candidate for the future wireless networks and as well as an essential part of experimental radio astrophysics. Understanding the underline physics of the element performance in the array environment is paramount to develop and improve the performance of array systems. The focus of this thesis is to develop novel wideband antenna array technologies and develop new theoretical insights of the fundamental limits of antenna arrays. The developed methodologies have also been extended to include a radio astrophysics application for the global 21cm experiment.   Investigating the fundamental antenna array limits and extracting general performance measures can provide a priori estimates for any application of arrays. In this thesis, a general measure for antenna arrays, the array figure of merit is proposed. This measure couples bandwidth, height from the ground plane and reflection coefficient in a bounded quantity. An extension of the array figure of merit that is able to provide matching, bandwidth and directivity/gain limits is also introduced. The soft Vivaldi array is introduced as a novel wideband, wide-scan angle array technology. Periodic structure loading has been utilized to improve the array's performance and mold the electromagnetic wave behavior to our benefit. The soft condition has been utilized in the same manner as the conventional soft-horn antenna at the Vivaldi element. An integrated matching layer in the form of periodic strip loading is introduced. A single polarized soft Vivaldi array prototype has been developed fabricated and measured. The developed finite array has been loaded with a soft condition in the periphery to mitigate edge effects. The results indicated improved cross-polarization and side-lobe levels. A new class of wideband antenna arrays, the Strongly Coupled Asymmetric Dipole Array (SCADA) was also proposed in this thesis. Exploiting asymmetry in the array element introduces an additional degree of freedom that improves bandwidth and scanning performance. A novel methodology for terminating finite arrays is also proposed. The theory and an experimental antenna array is presented with good agreement between measured and simulated results. An effort to integrate a vertical wide angle matching layer was also addressed and a prototype array with this concept is presented. In the last part of this thesis, a methodology for the detection of the global cosmological 21cm signal from the Epoch of Reionization (EoR) is developed. The main sources of errors in this experiment, the foregrounds and the antenna chromaticity are evaluated. A new algorithmic methodology for extracting the global EoR signal is proposed. The method is based on piecewise polynomial fitting and has successfully been applied and evaluated. An antenna array that is based on the methodologies described in this thesis has been developed and evaluated with the proposed algorithm. / Bredbandiga gruppantenner med stor utstyrningsvinkel är en av de lovande kandidaterna för nästa generations trådlösa kommunikationsnätverk samt en väsentlig del av experimentell radioastrofysik. Att förstå de bakomliggande fysikaliska principerna hos gruppantennens element är avgörande för att kunna utveckla och förbättra prestandan hos ett gruppantennsystem. Denna avhandling är fokuserad på att utveckla nya bredbandstekniker samt nya teoretiska insikter om de grundläggande gränserna för gruppantenner. De här utvecklade metoderna har förutom kommunikationstillämpningar också tillämpats på en radioastrofysik tillämpning i det globala 21cm experimentet. Att undersöka de fundamentala gränserna för gruppantenner och att utröna allmängiltiga mått på deras prestandaegenskaper kan möjliggöra a priori uppskattningar om gruppantenns tillämpbarhet för dess planerade användning. I den här avhandlingen föreslås ett allmänt kvalitetsmått på gruppantenner: gruppantennkvaliten. Detta mått kopplar samman främst bandbredd, reflektionskoefficienten med antennens tjocklek över ett jordplanet. En utvidgning av begreppet gruppantennkvaliten, presenters också i avhandlingen det kopplar samman bandbredd, matchning med antennens direktivitet/förstärkningsfaktor. En Vivaldi-gruppantenn med mjuka ytor introduceras här som en ny sorts bredbandig gruppantenn med stor utstyrningsvinkel. I antennen har en periodisk belastning inkluderats för att förbättra dess egenskaper, och för att forma antennens elektromagnetiska utstrålning till vår fördel. Den mjuka ytan på elementet har används på ett liknande sätt som det välkända korrigerade Vivaldihornets design, och har integrerats direkt i elementets design. Den här utvecklade ändliga gruppantennen har också en mjuk yta på dess yttre delar för att minska kanteffekternas påverkan av antennprestandan. Resultaten indikerade både förbättrad korspolarisations och lägre sidlobsnivåer hos antennen. En ny klass av bredbandiga gruppantenner har utvecklas i denna avhandling, den kallas en Starkt Kopplad Asymmetrisk Dipol-gruppAntennen - SCADA. Genom att utnyttja geometrisk asymmetri i antennelementet introduceras ytterligare en frihetsgrad som möjliggör förbättrad bandbredd och utstyrning. Vidare presenteras här en ny metod för impedansterminering av ändliga gruppantenner. Både SCADA-teorin samt dess verifiering i forma av en experimentell gruppantenn presenteras här. Teori, simulering och experiment visar god överenskommelse, vilket validerar idéerna. En prototyp av ett matchande skikt som stöder stor utstyrbarhet har integrerats med gruppantennprototypen och presenteras i avhandlingen. I den sista delen av avhandling utvecklas också en metod för detektering av den globala kosmologiska 21 cm-signalen från universums rejoniseringsepok - EoR. Huvudkällorna för mätfel i detta experiment utvärderas, de är antennens kromaticiteten och förgrundsstrålningen. En ny algoritmbaserad metod för att extrahera den globala EoR-signalen föreslås. Metoden är baserad på anpassning med multipla polynom och har med framgång tillämpats och utvärderats. En gruppantenn som baseras på de metoder som beskrivs i avhandling har också föreslagits och dess prestanda har utvärderats med den föreslagna metoden. / <p>QC 20171121</p>
89

Characterization of the Red Bluff Landslide, Greater Cascade Landslide Complex, Columbia River Gorge, Washington

Randall, James Robert 11 December 2012 (has links)
Located in the Columbia River Gorge, The Red Bluff Landslide (18.8 km2) is one of four large landslides that make up the Cascade Landslide Complex. In its current form, the Red Bluff Landslide is a post-Missoula Flood feature made up of two components: an active upper lobe (8.6 km2) that is translational, creeping to the south at 25 cm/yr and spreading laterally to the east at 6 cm/yr over a semi-fixed portion (10.2 km2) of the Red Bluff Landslide area that has been "smoothed" by Missoula Floods. The upper active lobe is the landslide debris accumulated since Missoula Flood time (~15,000 yr. BP). Five separate collapse events have been identified and rock failures along the main scarp headwalls continue. Two rock avalanches on the Red Bluff Landslide were mapped. The Old Greenleaf Basin Rock Avalanche is estimated to have occurred 100 to 150 years ago, represents the fifth collapse event on the Red Bluff Landslide, and covers an area of 200,000 m2. It has a volume of 4.2 million m3; its length is 748 m and has a width of 215 m. On January 3, 2008, the Greenleaf Basin Rock Avalanche occurred, flowing over the Old Greenleaf Basin Rock Avalanche, covering an area of 100,000 m2 and deposited a volume of about 375,000 m3. Its length is 730 m with an average depth of 1.22 m. It contributed approximately 0.058% of the total volume and 0.01% of the surface area to the active upper lobe portion of the Red Bluff Landslide. The Greenleaf Basin Rock Avalanche was determined to be insignificant in the movement of the active part of the Red Bluff Landslide during the winter of 2007-2008. The original Cascade Landslide Complex map (Wise, 1961) included the Mosley Lakes Landslide which has now been removed because it lacked the characteristics of a landslide like a scarp. The original complex (35.5 km2) has been renamed the "Greater Cascade Landslide Complex" (43.0 km2), with the addition of the adjacent Stevenson Slide and the elimination of the Mosley Lakes Landslide.
90

Aspekty vyhodnocení měření GNSS / Aspects of GNSS Processing

Puchrik, Lukáš January 2013 (has links)
The thesis deals with processing of epoch-wise GNSS measurements from local geodynamic network Sněžník. Its aim is to evaluate the geodynamics in the area of Králický Sněžník Massif and to assess the capabilities of epoch-wise GNSS measurements to detect the geodynamic movements. Within the thesis the comprehensive processing of all the GNSS measurements observed between years 1997 and 2011 is realized using the reprocessed products of first IGS reprocessing Repro1. Bernese GPS software version 5.0 is used for all the processing.

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