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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Gasdermins: A Lattice Network of Cell Death Effectors

Zhou, Bowen 23 May 2022 (has links)
No description available.
2

DEFINING EOSINOPHIL INFLAMMASOME SIGNALING DEPENDENT AND GASDERMIN DRIVEN IL-1β RELEASE

Diaz Aponte, Jose Enrique January 2022 (has links)
No description available.
3

Inflammatory Pathways in the Macrophage Response to Orthopaedic Wear Particles

Fort, Brian P. January 2020 (has links)
No description available.
4

Active Gasdermin D Forms Plasma Membrane Pores and Disrupts Intracellular Compartments to Execute Pyroptotic Death in Macrophages During Canonical Inflammasome Activation

Russo, Hana 07 September 2017 (has links)
No description available.
5

Cell Death Pathways Drive Necroinflammation during Acute Kidney Injury

Mässenhausen, Anne von, Tonnus, Wulf, Linkermann, Andreas 04 August 2020 (has links)
Renal tubules represent an intercellular unit and function as a syncytium. When acute tubular necrosis was first visualized to occur through a process of synchronized regulated necrosis (SRN) in handpicked primary renal tubules, it became obvious that SRN actually promotes nephron loss. This realization adds to our current understanding of acute kidney injury (AKI)-chronic kidney disease (CKD) transition and argues for the prevention of AKI episodes to prevent CKD progression. Because SRN is triggered by necroptosis and executed by ferroptosis, 2 recently identified signaling pathways of regulated necrosis, a combination therapy employing necrostatins and ferrostatins may be beneficial for protection against nephron loss. Clinical trials in AKI and during the process of kidney transplantation are now required to prevent SRN. Additionally, necrotic cell death drives autoimmunity and necroinflammation and therefore represents a therapeutic target even for the prevention of antibody-mediated rejection of allografts years after the transplantation process.
6

Non-Pyroptotic Gasdermin-B (GSDMB) Regulates Epithelial Restitution and Repair, and is Increased in Inflammatory Bowel Disease

Rana, Nitish 23 May 2022 (has links)
No description available.

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