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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

A morphometric assessment of pre-neoplastic and neoplastic conditions in the gastrointestinal system

Hamilton, Peter William January 1989 (has links)
No description available.
2

Neuroendocrine regulation of gastric endocrine cell function

Higham, Andrew Damian January 1998 (has links)
No description available.
3

Relationship between Interstitia and Prognosis of Gastric Carcinoma

KONDO, TATSUHEI, KOBAYASHI, FUMIHIRO, HASEGAWA, YASUHISA, KOJIMA, TAKASHI, YAMAMURA, YOSHITAKA, TERABE, KEISUKE, KAMEI, HIDEO 01 1900 (has links)
No description available.
4

Die perioperative Chemotherapie des lokal fortgeschrittenen Magenkarzinoms nach Göttinger Erfahrung / Perioperative chemotherapy of locally advanced gastric carcinoma based on the experiences of Göttingen medical school

Röper, Dierck-Henrik 20 June 2012 (has links)
No description available.
5

Die Entwicklung von Immunoproteomics-Methoden am Beispiel der Identifizierung Magenkarzinom-assoziierter Helicobacter pylori Antigene

Krah, Alexander 20 December 2004 (has links)
Das magenbesiedelnde Bakterium Helicobacter pylori gehört zu den am weitesten verbreiteten Infektionserregern. Obwohl die Infektion meist lebenslang symptomlos verläuft, kann H. pylori bei einigen Menschen schwere Erkrankungen bis hin zum Magenkarzinom verursachen. Ziele dieser Arbeit waren Magenkarzinom-assoziierte Antigene für einen diagnostischen Test zu finden und Methoden zur Untersuchung von Spotkompositionen mittels MALDI-TOF/TOF Massenspektrometrie zu entwickeln. Im ersten Teil der Promotion wurden die Antigenerkennungsmuster von 30 Magenadenokarzinom- mit 30 Ulkus duodeni-Patienten mithilfe hochauflösender zweidimensionaler Immunoblots von H. pylori Lysat verglichen. Diese fokussierte Gegenüberstellung eignet sich gut für diese Fragestellung, da beide Erkrankungen von diesem Bakterium verursacht werden, aber nur sehr selten gemeinsam auftreten. Durch univariate statistische Analysen wurden 14 Magenkarzinom korrelierte Spots gefunden (p / The stomach-colonizing bacterium Helicobacter pylori is one of the most widespread infectious agents. Although infection mostly persists unnoticed, it may cause serious diseases like gastric carcinoma. Aims of this project were to find gastric carcinoma-associated antigens for a diagnostic test and to develop methods to analyze spot compositions using MALDI-TOF/TOF mass spectrometry. In the first part of this project antigen recognition patterns of 30 gastric carcinoma- and 30 duodenal ulcer- patients were compared using high-resolution two-dimensional immunoblots of H. pylori lysate. This focused comparison lent itself to this question because both diseases are caused by the bacterium but rarely occur conjointly. Utilizing univariate statistical tests 14 gastric carcinoma-associated spots were found (p
6

Optimalizace metodiky pro stanovení volné nádorové DNA v plazmě a její klinické využití u pacientů s karcinomy kolorekta, plic a slinivky břišní / Optimization of proces for detection of free tumor DNA in plasma and its clinical utility for colorectal cancer, lung cancer and pancreatic cancer patients

Belšánová, Barbora January 2017 (has links)
In current days, examination of circulating tumor DNA (ctDNA) finds new use across different cancers. It is directed at tumor-derived short fragments of DNA present in peripheral blood of patiens (mainly in advanced stages). Due to its minimal invasivity, almost 100 % specificity and relatively high sensitivity in stage IV patients, this approch found its main potential clinical utility especially in early detection of disease relapse or progression after tumor resection (i.e. post-operative follow-up), prediction and monitoring of therapy response and estimation of prognosis. As a result of minute levels of ctDNA on a high background of other non-tumor DNA fragments present in plasma, a suitable method exhibiting highest sensitivity is the key for proper detection of this marker. The approach is predominantly based on initial identification of a mutation in tumor tissue and its subsequent detection in plasma. The present work is aimed at optimization of ctDNA isolation and method of its detection based on PCR amplification followed by heteroduplex analysis by denaturing capillary electrophoresis (DCE) to achieve highest sensitivity for detection of mutated fraction in plasma sample. I have applied the optimized protocol to examine ctDNA in three types of cancers, namely colorectal cancer (122...

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