281 |
Different cis-regulatory DNA elements mediate developmental stage- andtissue-specific expression of the human COL2A1 gene in transgenicmiceLeung, Kai-hung, 梁啓雄 January 1998 (has links)
published_or_final_version / Biochemistry / Doctoral / Doctor of Philosophy
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282 |
Evolution and dynamics of transcription factors and gene expression patternsCharoensawan, Varodom January 2011 (has links)
No description available.
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283 |
Regulation of starvation-induced gene expression in Saccharomyces cerevisiaeQuan, Zhenzhen January 2012 (has links)
No description available.
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284 |
Investigating the molecular mechanism of thiostrepton inhibition of FOXM1 activityHegde, Nagaratna Shridhar January 2012 (has links)
No description available.
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285 |
Prediction of gene expression in embryonic structures of Drosophila melanogasterSamsonova, Anastasia A. January 2006 (has links)
No description available.
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286 |
Single cell gene expression profiling of human epidermal keratinocytesTan, Wei Min January 2011 (has links)
No description available.
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287 |
Targeted degradation of RNA by RNase H using stable DNA hairpin oligomers and a study on the effect of temperature and divalent cations on RNA conformational statesLi, Jing 12 1900 (has links)
No description available.
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288 |
Genetic analysis of the cellular control of [PSI] prionZink, Amy Darlene 12 1900 (has links)
No description available.
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289 |
Underexpression of paternal genes in sea urchin interspecies hybrid embryosConlon, Ronald A. January 1985 (has links)
No description available.
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290 |
The role of the 5 ́untranslated region in gene expression of ornithine aminotransferaseMacDonald, Heather R. (Heather Ruth) January 1995 (has links)
Ornithine-$ delta$-biaminotransferase (OAT) is a mitochondrial matrix a enzyme which catalyzes the reversible conversion of ornithine to glutamic semialdehyde. In the retinoblastoma cell line Y79, the 5$ sp prime$ UTR of the OAT mRNA is alternatively-spliced. Previous work has shown that the two alternatively-spliced 5$ sp prime$ UTR are translated with different efficiencies. / The alternatively-spliced 5$ sp prime$ UTRs were isolated and subcloned. Expression vectors were constructed containing each of the OAT 5$ sp prime$ UTRs and the human growth hormone as a reporter gene. Transient transfection expression analysis in COS-1 cells confirmed that the 5$ sp prime$ UTRs conferred differential expression on the reporter gene. The shorter 5$ sp prime$ UTR was expressed at a level 3-fold higher than that of the longer 5$ sp prime$ UTR. / RNA mobility shift assays were performed to determine whether a transacting factor was interacting with one of the alternatively-spliced 5$ sp prime$ UTRs. A binding activity was detected that bound to the longer, exon 2-containing 5$ sp prime$ UTR with a significantly higher affinity than the shorter 5$ sp prime$ UTR. Competition studies demonstrated that this binding activity was specific for the longer 5$ sp prime$ UTR.
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