Thesis (M.S.)--Tsing Hua University, 1960. / Research done at the University of Michigan.

An open question in contemporary neuroscience is how neuromodulators coregulate multiple conductances to maintain functional neuronal activity. Neuromodulators enact changes to properties of biophysical characteristics, such as the maximal conductance or voltage of half-activation of an ionic current, which determine the type and properties of neuronal activity. We apply dynamical systems theory to study the changes to neuronal activity that arise from neuromodulation. Neuromulators can act on multiple targets within a cell. The coregulation of mulitple ionic currents extends the scope of dynamic control on neuronal activity. Different aspects of neuronal activity can be independently controlled by different currents. The coregulation of multiple ionic currents provides precise control over the temporal characteristics of neuronal activity. Compensatory changes in multiple ionic currents could be used to avoid dangerous dynamics or maintain some aspect of neuronal activity. The coregulation of multiple ionic currents can be used as bifurcation control to ensure robust dynamics or expand the range of coexisting regimes. Multiple ionic currents could be involved in increasing the range of dynamic control over neuronal activity. The coregulation of multiple ionic currents in neuromodulation expands the range over which biophysical parameters support functional activity.

Failure of Alloy 600 steam generator tubing in Pressurised Water Reactors (PWRs) has prompted the investigation of alloy 690 as an alternative material. Six commercially produced tubes and ten experimentally produced alloys have been examined with varying amounts of carbon, aluminium and titanium. Alloy compositions have been selected to investigate the individual and combined effects of these elements on the microstructure and corrosion behaviour in the environments of corrosion tests and simulated PWR conditions. Alloys were subjected to simulated mill annealing treatments at varied temperatures. Microstructural characterisation using optical and electron microscopy has demonstrated the effects of composition and thermal treatment in controlling grain size and carbide precipitation together with the interdependence between these structural details. Stress corrosion resistance of selected alloy 690 tubes has been examined with samples in an autoclave at fixed temperatures with environments based on pure water, sodium hydroxide and sodium hydroxide + sodium sulphate solutions. Susceptibility to intergranular attack has been related to aluminium contents of the alloy and to thermal treatments given. Results suggest a decreased resistance to IGA when aluminium is increased. Thermal treatments given to the samples appear not to be very significant to the amounts of IGA. The compositions and heat treatments used in the corrosion study were further examined on a dedicated scanning transmission electron microscope in order to correlate the effects of, chromium depletion, nickel enrichment and impurity segregation at grain boundaries, with corrosion characteristics. These results have shown the effect of varying the special thermal treatment temperature and time on the degree of enrichment / depletion / segregation and the corrosion resistance of the alloy. The mechanism of protection afforded by the special thermal treatment can thus be elucidated.

Cognition, the topic of this dissertation, is a music market arcade for Gallo Records that will act as a platform for aspiring South African musicians. The concept of the musician and the status of the musician in society varies from culture to culture. Thus the topic will explore the social implications music has on different cultures by addressing diversion in a social context. Music will therefore act as generator by merging culture and creating an awareness and common ground by acting as the universal medium. In doing so,the musician will indirectly compose a South African identity by means of public performance. / Dissertation (MArch(Prof))--University of Pretoria, 2008. / Architecture / unrestricted

No description available.

Optical microlasers have been used in different engineering fields and for sensing various applications. They have been used in biomedical fields in applications such as for detecting protein biomarkers for cancer and for measuring biomechanical properties. The goal of this work is to propose a microfluidic-based fabrication method for fabricating optical polymer based microlasers, which has advantages, over current methods, such us the fabrication time, the contained cost, and the reproducibility of the microlaser's size. The microfluidic setup consisted of microfluidic pumps and a flow focusing droplet generator chip made of polydimethylsiloxane (PDMS). Parameters such as the flow rate (Q) and the pressure (P) of both continuous and dispersed phases are taken into account for determining the microlaser's size and a MATLAB imaging tool is used to reduce the microlaser's diameter estimation. In addition, two applications are discussed: i) electric field measurements via resonator doped with Di-Anepps-4 voltage sensitive dye, and ii) strain measurements in a 3D printed bone-like structure to mimic biomedical implantable sensors.

In conventional centralized power systems, power is generated mostly by large synchronous generators (SGs), where the frequency of the grid depends on the rotational frequency of the prime mover. If there are any sudden changes in the load, the rotor inertia property restrains the changes in frequency and keeps the system stable. During transient periods, rotor kinetic energy of the rotor is injected into the grid to balance power supply between generation and load. With the recent high penetration of renewable energy sources (RES), the power grid is undergoing structural changes with an increased inverter-based distributed generation. Since inverter based power sources do not have inertia as conventional synchronous machines (SM), high penetration of inverters may cause instability and sharp voltage fluctuations in the grid. If inverter based power sources could be configured as regular SM by introducing virtual inertia and damping property, many of the problems, such as frequency regulation, islanded operation, and parallel operation of inverter-based DGs will be resolved. This thesis investigates mathematical modeling and control of VSG’s to emulate the inertia and damping property of SMs. Simulation results are presented on the modeling and closed-loop performance of VSGs for an island microgrid. / Electrical and Computer Engineering

Ultra-Wideband (UWB) technologies are at the forefront of wireless communications, offering the possibility to provide extremely high data rate wireless solutions. In addition to high data rate applications, UWB technologies also offer an extremely low cost alternative for many low data rate systems. In this thesis, we describe the design of a CMOS pulse generator for impulse based UWB systems. The structure of our pulse generator is based on the topology of a single tap CMOS power amplifier. By increasing the number of taps on a CMOS power amplifier, it is possible to generate sub-nanosecond pulses with a desired shape. A power saving scheme that significantly reduces the power consumed at low data rates is also described. The versatility of our design lies in the ability to support dynamically varying output power levels and center frequencies. Our pulse generator design is extended to a rectified cosine generator, necessary for a multiband approach. The performance of our pulse generators is estimated through simulation with a target technology of TSMC 0.18 µm CMOS at a supply voltage of 1.8 V. The simulation results indicate that our pulse generator produces high fidelity Gaussian monocycle pulses with a pulse width of approximately 160 ps and a peak output power of more than 10 mW. We believe that our design of a CMOS pulse generator for UWB systems is a feasible option for many applications in which power and cost are most important. / Master of Science

No / The conventional summation generator (SG) has been broken in the past using a number of different methods. Recently, a modified SG was proposed by Lee and Moon to increase the resistance of such generators against these attacks. However, this paper shows that even the modified generator is still vulnerable to correlation attacks.

The thesis reports the results of comprehensive studies carried out to explore the impact of midpoint FACTS Controllers (STATCOM and SVC) on the generator distance phase backup protection in order to identify important issues that protection engineers need to consider when designing and setting a generator protection system. In addition, practical, feasible and simple solutions to mitigate the adverse impact of midpoint FACTS Controllers on the generator distance phase backup protection are explored. The results of these studies show that midpoint FACTS Controllers have an adverse effect on the generator distance phase backup protection. This adverse effect, which can be in the form of underreach, overreach or a time delay, varies according to the fault type, fault location and generator loading. Moreover, it has been found that the adverse effect of the midpoint FACTS Controllers extends to affect the coordination between the generator distance phase backup protection and the generator steady-state overexcited capability limit. The Support Vector Machines classification technique is proposed as a replacement for the existing generator distance phase backup protection relay in order to alleviate potential problems. It has been demonstrated that this technique is a very promising solution, as it is fast, reliable and has a high performance efficiency. This will result in enhancing the coordination between the generator phase backup protection and the generator steady-state overexcited capability limit in the presence of midpoint FACTS Controllers. The thesis also presents the results of investigations carried out to explore the impact of the generator distance phase backup protection relay on the generator overexcitation thermal capability. The results of these investigations reveal that with the relay settings according to the current standards, the generator is over-protected and the generator distance phase backup protection relay restricts the generator overexcitation thermal capability during system disturbances. This restriction does not allow the supply of the maximum reactive power of the generating unit during such events. The restriction on the generator overexcitation thermal capability caused by the generator distance phase backup protection relay highlights the necessity to revise the relay settings. The proposed solution in this thesis is to reduce the generator distance phase backup protection relay reach in order to provide secure performance during system disturbances.