This master's thesis is focused on modern methods and tools to support managerial decision-making. The first part of this thesis introduces the basic characteristics related to the management and managerial decision-making that are subsequently extended to the area of modeling, simulation, optimization and multi-criteria decision making. It also outlines the relationship between the managerial decision-making tasks. The second part introduces practical examples which show the connection of these areas. Specifically, they are a colony of ants, traveling salesman problem, a tool AnyLogic, analytic hierarchy process and simulation HealthBound. The thesis is further supplemented by an appropriate software tools to support multi-criteria decision making.

This diploma thesis focuses on meta-heuristic algorithms and their ability to solve difficult optimization problems in polynomial time. The thesis describes different kinds of meta-heuristic algorithms such as genetic algorithm, particle swarm optimization or ant colony optimization. The implemented application was written in Java and contains ant colony optimization for capacitated vehicle routing problem and particle swarm optimization which finds the best possible parameters for ant colonies.

First part of the thesis is about literature research of optimization algorithms. Three of the algorithms were implemented and tested, concretely the ant colony algorithm, tabu search and simulated annealing. All three algorithms were implemented to solve the traveling salesman problem. In second part of the thesis the algorithms were tested and compared. In last part the influence of the ant colony parameters was evaluated.

This master thesis deals with image processing of Petri dishes. The first part is about terms and procedures in laboratory practice. The following part is about devices and algorithms for image analysis of Petri dishes. The second part is about draft and implementation of own colony counting application, which was developed in cooperation with the microbiological laboratory. The application is developed for mobile devices running Android OS. The master thesis also includes the design and creation of two lighting units, which uses as an accessory for better results in the analysis of Petri dishes. In conclusion are presented results, compared lighting units and various types of mobile devices, on which the application was tested.

Spanish-Dutch Relations in the New World during the Existence of the West Indische Compagnie Eva Kubátová Abstract This dissertation is dedicated to the Spanish-Dutch relations in the New World during the existence of the first Dutch West India Company (1621-1674). On base of an imagological analysis, this thesis presents elements of mutual relations, reflected in hetero-images, together with self-representation of both analyzed parties (thus self-image) within the ongoing conflict of the Eighty Years' War. The imagological analysis is applied on archival material, chiefly the Dutch pamphlets and Spanish Relaciones de sucesos (which can be translated as "Treatises of Successes"). The result of this thesis is then an analysis of development and changes of mutual images, upon the historical events of the Spanish-Dutch war conflict: thus since the beginnings of the Dutch Revolt, passing through the Twelve Years' Truce, until the signature of the Peace of Westphalia in 1648. A special emphasis is put to the final phase of the Eighty Years' War, in this thesis delimited by the years 1621-1648, which was marked by the official entrance of the West India Company into the Spanish waters of Greater Caribbean. An important watershed in mutual relations is afterwards represented by the Peace of Westphalia, which...

Mediální obraz zahrádkářských kolonií ve vybraných českých denících Abstract Abstract The aim of this thesis is the media presentation of gardening allotments phenomena in Czech Republic. The work is in a connection with a series of thesis published during previous years on Social and Cultural Ecology department of Faculty of Humanities, Charles Univerisity. These thesis were focused on qualitatative case studies research of garden allotments. Aim of this theis is a revelation of garden allotments image, based on processing of czech daily press articles mentioning allotment gardening. First, theoretical, part of the thesis is organized into four chapters: hermeneutics, allotment gardening, media and sustainable development. Each of the chapters provides a context of the main purpose of the work. Methodological anchor and the research and its results itself follow on at the third part of this thesis.

This diploma thesis deals with ant colony optimization for shortest path problems. In the theoretical part it describes Ant Colony Optimization. In the practical part ant colony optimization algorithms are selected for the design and implementation of shortest path problems in the Java.

This work deals with the issue of swarm intelligence as a subdiscipline of artificial intelligence. It describes biological background of the dilemma briefly and presents the principles of searching paths in ant colonies as well. There is also adduced combinatorial optimization and two selected tasks are defined in detail: Travelling Salesman Problem and Quadratic Assignment Problem. The main part of this work consists of description of swarm intelligence methods for solving mentioned problems and evaluation of experiments that were made on these methods. There were tested Ant System, Ant Colony System, Hybrid Ant System and Max-Min Ant System algorithm. Within the work there were also designed and tested my own method Genetic Ant System which enriches the basic Ant System i.a. with development of unit parameters based on genetical principles. The results of described methods were compared together with the ones of classical artificial intelligence within the frame of both solved problems.

This work addresses the history, development and conservation of the Werkbund exhibition estates in Europe. Specifically, these are six housing estates built between 1927-1932 in Stuttgart, Brno, Wroclaw, Zurich, Vienna and Prague as part of exhibitions of modern living. The aim is to compare the development in individual cities and above all their preservation and the way of conservation and restoration. The first chapter deals with the formation of colonies and their differences. In the next part we deal with the fate and the structural changes during the war and the first post-war years until the first colony was declared a monument. The third chapter explains the developments in the 1960s and early 1980s, the beginnings of monument conservation and the first comprehensive renovation of the housing estates. The last chapter focuses on today's housing estates, today's approach to the restoration of functionalist architecture and its pitfalls. In all chapters, we managed to compare the development and to show the specifics of the individual files, which made it possible to specify why the colonies need to be protected, the extent to which they are preserved today, how much they are preserved, and what problems the building regeneration brings. Due to the different status and approach in individual...

(ENGLISH) Hematopoiesis is dependent on the actions of hematopoietic stem cells (HSCs). This process is tightly controlled through a complex array of extrinsic and intrinsic factors. Even though the hematopoiesis seems to be well conserved across the disparate vertebrate animals, erythroid and thrombocytic differentiation have changed during the evolution of mammals. Specifically, adult mammalian red blood cells have the unique feature of being enucleated, and mammalian thrombocytes are not individual cells, but fragments of megakaryocytes, instead. It is likely that these enhancements provided a survival advantage to early mammalian species; however, they also bring up the question of evolutionary origin of these cells that studied using zebrafish (Danio rerio) model. First, it was necessary to generate a toolbox of a recombinant cytokines and optimized culture media that allowed us to manipulate zebrafish hematopoietic cells ex vivo in liquid and clonal cultures. Interestingly, teleost species underwent an extra duplication event during their evolution and as a result, two copies (paralogs) of some of the genes are present in zebrafish. This was also the case for majority of the cytokines from our toolbox and here, we provide functional characterization of these paralogs. Strikingly, our results...