Neste trabalho estudamos a interação feixe-plasma aplicando a teoria de turbulência fraca. Primeiramente fazemos uma introdução `a teoria cinética de plasmas, estudando aspectos fundamentais como: a abordagem estatística das equações do plasma, o tratamento a ser dado `as funções de correlação que aparecem nessa abordagem, e o sistema de equações de Vlasov-Maxwell. Em seguida estudamos a aproximação de Vlasov e a solução do sistema de Vlasov- Maxwell na aproximação linear, enfocando a descrição de ondas no plasma e o amortecimento de Landau. Ao longo desse desenvolvimento fazemos uma apresentação relativamente detalhada dos procedimentos introduzidos por Landau ao tratar o sistema Vlasov-Maxwell como um problema de valor inicial, incluindo uma discussão sobre a resolução de integrais no plano complexo, com polos no denominador, e a solução da relação de dispersão para encontrar os modos normais de oscilação no plasma. Apresentamos também uma breve revisão a respeito da aproximação quase-linear do sistema de Vlasov- Maxwell, na qual abordamos a obtenção da equação quase-linear de difusão no espaço das velocidades para partículas e estudamos suas propriedades de conservação. Nesse contexto da teoria quase-linear, apresentamos uma revisão a respeito da evolução temporal do amortecimento de Landau no caso de distribuição de velocidades Maxwelliana e da instabilidade que pode ocorrer no caso de uma função distribuição com um feixe de partículas. Depois dessa introdução `a aproximação linear e `a teoria quase-linear, abordamos a teoria de turbulência fraca num plasma não magnetizado, incluindo interações não lineares entre ondas e partículas. O formalismo apresentado inclui efeitos como emissão espontânea e induzida, decaimento e espalhamento de ondas. O sistema de equações acopladas da teoria de turbulência fraca é então reduzido a uma aplicação a um sistema considerando duas dimensões, depois reescrito em termos de coordenadas polares e adaptado para solução numérica. Apresentamos então uma descrição do código numérico desenvolvido usando linguagem Fortran, abordando um plasma com elétrons descritos por uma função distribuição Maxwelliana com um feixe tênue, e íons descritos por uma função distribuição Maxwelliana. Finalmente, comparamos nossos resultados com outros obtidos por outros autores em trabalhos anteriores, desenvolvidos usando coordenadas cartesianas, avaliando nosso trabalho. Por último, discutimos algumas perspectivas para o desenvolvimento futuro do trabalho. / In the present work we study the beam-plasma interaction using the weak turbulence theory. We start with an introduction to the kinetic theory of plasmas, studying fundamental features, like the statistical approach to the plasma equations, the procedures to be employed to deal with the correlation functions appearing in the statistical approach, and the system of Vlasov-Maxwell equations. In the sequence we discuss the Vlasov approximation and the solution of the Vlasov- Maxwell system in the linear approximation, emphasizing the description of waves in the plasma and the Landau damping. Along the development we present a relatively detailed description of the procedures introduced by Landau to treat the Vlasov-Maxwell system as an initial value problem, including a discussion about the resolution of integrals in the complex plane, with poles in the denominator, and the solution of the dispersion relation to find the normal mode of oscillations in the plasma. We also present a short review about the quasilinear approximation of the Vlasov-Maxwell system, in which we discuss the derivation of the quasilinear diffusion equation in the space of particle velocities, and study its properties of conservation. In the context of the quasilinear theory, we present a short review about the time evolution of the Landau damping in the case of Maxwellian velocity distribution, and about the instability which can occur in the case of a distribution function with a beam of particles. After the introduction to the linear approximation and to the quasilinear theory, we present the equations of weak turbulence theory for a unmagnetized plasma, including non-linear interactions between waves and particles. The formalism which is presented includes effects and spontaneous and induced emission, decay and scattering of waves. The system of coupled equations of the weak turbulence theory is then reduced to application to a bi-dimensional case, and then re-written in terms of polar coordinates and adapted to numerical solution. We then present a description of the numerical code developed using Fortran language, suitable to describe a plasma with electrons described by a Maxwellian distribution function with a tenuous beam, and ions described by a Maxwellian distribution. Finally, we compare our results with results obtained by other authors in previous works, developed using cartesian coordinates, as a validation of our work. Lastly we discuss some perspectives for future developments.

Orientadores: Peter Jurgen Tatsch, Stanislav A. Moshkalyov / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica e de Computação / Made available in DSpace on 2018-08-11T19:17:46Z (GMT). No. of bitstreams: 1 Besseler_Edmilson_M.pdf: 3143419 bytes, checksum: 2715af82a31f1728537a14b1764455a6 (MD5) Previous issue date: 2008 / Resumo: Esta dissertação apresenta as etapas do trabalho de construção de um Reator ICP destinado a processos de micro fabricação, mais precisamente, destinado a corrosões profundas de Silício a taxas de corrosões elevadas. O modelamento e as caracterizações do reator ICP foram feitas através de um protótipo e depois aplicadas a um equipamento da LAM Research que funcionava em modo RIE. Este foi adaptado para trabalhar em modo ICP, de acordo com os parâmetros obtidos no protótipo. Para isso, foi necessário a instalação do Equipamento e fornecer toda a infra-estrutura que este necessitava para seu funcionamento. Foram desenvolvidos casadores de impedância para ligação dos geradores de RF à bobina do ICP e do eletrodo de polarização da amostra, controladores de fluxo de gases, chaveadores manuais para válvulas pneumáticas, sistemas de refrigeração e tubulação de vácuo. O plasma foi caracterizado e alguns processos foram realizados com o intuído de mostrar o comportamento com relação à variação de parâmetros como pressão, potência, polarização da amostra, fluxo de gases, tempo de processo, área da lâmina exposta ao plasma e também o comportamento de diferentes tipos de máscaras. O Equipamento também foi preparado para que seja possível a comutação de gases, que futuramente será automática, de modo que se possa realizar corrosões e polimerizações consecutivas, como ocorre em processos Bosch. / Abstract: This dissertation shows the steps to building an ICP Reactor dedicated to micro fabrication process, further to deep etching of Silicon on high rates. The modeling and characterization of ICP Reactor has been done in a prototype and after applied on an RIE equipment from LAM Research, that was adapted to work in ICP mode like the prototype. To do it was necessary equipment installation and give it the infra structure needed to it works. A network matching was developed to connect the RF generator to ICP coil and to the electrode of wafer polarization, such as gas flow controllers, manual switches for pneumatic valves, cooling systems and vacuum pipes. The plasma was characterized and some processes has been realized in order to show the trends against some parameters variation as pressure, power, sample polarization (bias), gas flow, process time, wafer area exposed to the plasma and also the behavior of different kind of masks. The equipment is ready to switch some gases, which will be automatic in the future, to corrosion and polymerization consecutive process as at a Bosch process. / Mestrado / Eletrônica, Microeletrônica e Optoeletrônica / Mestre em Engenharia Elétrica

The diploma thesis is focused on the study of low-temperature plasma by methods of computational physics, namely particle modelling. The solution focuses on the time- effective execution of simulations, which is concerned, among the other things, with the use of parallelization techniques aimed at maximize shortening of the calculation time. The Langmuir probe was chosen as the most common representative of the probe diagnostics. The main goal of this work was to observe plasma interaction with the embedded solid. Current research on plasma modelling intensively explores dynamic phenomena such as wave propagation or turbulence and instability. For this reason, much of the work is devoted to the dynamics in electropositive and electronegative plasma.

L’objection générale de ces travaux est de comprendre les mécanismes d’interaction de molécules d’intérêt avec les membranes afin de faciliter la synthèse de molécules plus efficaces contre leurs cibles tout en étant moins toxique pour l’Homme. Dans la première partie de ces travaux, nous avons étudié les interactions entre ces modèles membranaires et les polyènes antifongiques, connus pour interagir avec les stérols des membranes plasmiques. Nous nous sommes particulièrement intéressés à la Nystatine et à l’Amphotéricine B, deux molécules de structure chimique très proche et actuellement utilisées dans l’industrie pharmaceutique. L’utilisation de différents modèles membranaires et de techniques adaptées a montré que la PhosphatidylEthanolamine avait très vraisemblablement un rôle primordial dans le mécanisme d’interaction de ces molécules avec les membranes. Dans la deuxième partie de ces travaux, nous nous sommes intéressés à l’inhibition de la formation du cristal d’hémozoïne formé lors de la croissance du parasite responsable du paludisme. Ce cristal est formé d’hématine, hautement toxique pour le parasite. L’hématine et l’inhibition de la formation de l’hémozoïne constituent une cible moléculaire idéale pour combattre cette maladie. La chloroquine, la méfoquine et de nouveaux inhibiteurs dérivés de la méfloquine ont été utilisés. L’étude de l’inhibition de la formation du cristal s’est faite en utilisant des monocouches de Langmuir, servant ainsi de biocapteurs. Ces travaux ont montré que l’énantiomérie, mais aussi la lipophilicité des nouveaux composés antipaludiques sont des paramètres importants en vue de la synthèse de molécules plus efficaces. / The main purpose of this work is to better understand the mechanisms of interaction between pharmaceutical relevant molecules and model membranes in order to facilitate the synthesis of new molecules, more efficient against their molecular target and less toxic for Humans. In the first part, we studied the interactions occuring between these models and antifungal polyene molecules. It has been reported that these molecules interacted preferentially with sterols. We specifically focused on Nystatin and Amphotericin B, two polyenes with a very similar chemical structure and presently used as a treatment against fungi and molds. Using different kind of model membranes, we showed PhosphatidylEthanolamine could have a very important role in the mechanism of action of these molecules. In the second part of this work, we studied the inhibition of the formation of a cristal called « hemozoïn », which is growing during the life cycle of the parasite responsible of malaria. This cristal is made of hematin, a toxic by-product of the degradation of hemoglobin, the main source of amino-acids for the parasite. Hematin and the inhibition of the growth of this cristal is a ideal molecular target to combat malaria. Chloroquine, mefloquine and new mefloquine-derivatives were studied. The study of the inhibition of the formation of the cristal was done using Langmuir monolayers as a biosensor. We showed that stereochemistry, but also lipophilicity of these compounds, are important parameters for the synthesis of more efficient antimalarial molecules.

Au cours de ce travail, nous nous sommes intéressés à l’élaboration de cristaux photoniques colloïdaux d’architecture contrôlée afin d’étudier leur effet sur les spectres de photoluminescence de luminophores. Notre stratégie a été d’incorporer les émetteurs au sein des particules de silice composant les cristaux colloïdaux de façon à les répartir de manière homogène dans l’ensemble des matériaux. Nous présentons la synthèse des précurseurs minéraux et l’élaboration de cristaux colloïdaux d’épaisseur contrôlée à la couche près grâce à la technique de Langmuir-Blodgett. Ces structures sont caractérisées par une bande interdite qui affecte la propagation de la lumière. L’insertion d’une couche de particules de diamètre différent dans un cristal colloïdal induit l’apparition d’une bande passante au sein de la bande interdite. Nous avons ainsi étudié l’influence de la structure de cristaux avec et sans défaut(s) sur les spectres d’émission de différents luminophores. Nous avons observé une inhibition et une exaltation locale de la lumière émise dans les zones spectrales correspondant respectivement aux bandes stoppante et passante. Nous avons également observé des modifications réversibles des spectres de photoluminescence des émetteurs, lorsque ceux-ci sont incorporés au sein de cristaux colloïdaux dont les propriétés optiques peuvent être modulées via l’application d’un stimulus extérieur. / During this work, we were interested in the elaboration of colloidal photonic crystals with a controlled architecture to study their effect on the photoluminescence spectra of emitters. Our strategy was to incorporate the emitters within the silica particles composing the colloidal crystals in order to distribute them homogeneously in the samples. We present the synthesis of the mineral precursors and the elaboration of colloidal crystals whose thickness is controlled at the layer level thanks to the Langmuir-Blodgett technique. These structures are characterized by a band gap which affects the light propagation. Insertion of a monolayer of particles with a different size as a planar defect within a colloidal crystal leads to the formation of a pass band in the band gap. We thus studied the effect of the structure of crystals with or without planar defect(s) on the emission spectra of different emitters. We observed local inhibition and exaltation of the emission in the spectral region corresponding to the stop band and the pass band, respectively. We have also observed reversible modulations of the photoluminescence spectra of the emitters when these ones were incorporated in colloidal crystals whose optical properties can be tuned by an external stimulus.

Cette thèse s’inscrit dans le cadre des études portant sur la toxicité des nanoparticules (NPs). Leurs propriétés physico-chimiques confèrent aux NPs la capacité de pénétrer dans les cellules en traversant la membrane plasmique. La compréhension de l’interaction NPs-membrane est donc cruciale. La structure complexe des membranes nous a imposé d’étudier l’interaction NPs-membrane à l’aide de films lipidiques plans (monocouches et bicouches) utilisés comme modèles membranaires simplifiés, déposés sur des surfaces nanostructurées par le dépôt préalable de NPs de silice (4 à 100 nm de diamètre) ou transférés à partir de monocouches étalées sur une suspension de NPs. Deux méthodes complémentaires ont été utilisées, la microscopie de force atomique (AFM) et la microscopie de fluorescence. Après une première phase d’optimisation des protocoles expérimentaux (choix des lipides, conditions de préparation des surfaces nanostructurées et des films), l’AFM a d’abord révélé l’oxydation des films monocouches constitués de lipides insaturés, se traduisant par la formation de domaines surélevés par rapport à la phase lipidique intacte. Dans le cas des films de lipides présentant une transition de phase de type liquide expansé/liquide condensé, la présence des NPs (le plus souvent sous forme d’agrégats) semble favoriser la transition vers la phase condensée, les NPs étant situés soit au coeur soit en lisière des domaines condensés.Dans le cas des bicouches, l’étude par AFM en milieu liquide montre des comportements tribologiques différents des agrégats de NPs, suggérant deux organisations possibles de la bicouche lipidique, recouvrant les NPs ou formant des pores autour d’elles. / The subject of this thesis fits into the large field of the toxicity of nanoparticles (NPs). Thanks to their physico-chemical properties, NPs are able to enter cells through the plasma membrane. Understanding the NPs-membrane interaction is thus very important. Membranes being complex structures, we chose to study this interaction using planar lipid films (monolayers and bilayers) as simplified membrane models, either deposited on nanostructured surfaces prepared by the prior deposition of silica NPs or transferred from monolayers spread on a subphase containing NPs (4-100 nm in diameter). Two complementary methods were used, atomic force microscopy (AFM) and fluorescence microscopy.After a first part devoted to the optimization of the experimental procedure (choice of lipids, design of nanostructured surfaces and films), AFM first revealed the oxidation of transferred monolayers made of unsaturated lipids, leading to the formation of domains raised above the intact lipid phase. In the case of films made of lipids characterized by a liquid expanded/liquid condensed phase transition, the presence of NPs (usually organized in aggregates) seems to favor the transition to the condensed phase, NPs being either embedded in condensed domains or at their edges.The final phase of this work was devoted to the study of NPs / bilayer interaction by AFM in liquid medium. The study shows different tribological behavior of NPs aggregates, suggesting two possible organizations of the lipid bilayer, covering the NPs or forming holes around them.

The ball-pen probe is a relatively new diagnostic method, that has been designed for direct measurement of plasma potential in magnetized plasmas. Nowadays, it is routinely used at several high-temperature plasma devices in Europe and it has been tested also in conditions of low-temperature plasma, which are substantially different from that of high-temperature plasma. The measurements performed so far showed, that ball-pen probe could be used also in low-temperature plasma. However, more measurements were needed to prove the applicability of ball-pen probe. Therefore, the main aim of this work is to compare the method of ball-pen probe with simultaneous measurements using Langmuir and emissive probe. Measurements were performed in DC discharge of cylindrical magnetron at various discharge conditions and radial positions of probes. Powered by TCPDF (www.tcpdf.org)

Amino acid phenylalanine plays a key role in numerous biological processes and is also involved in amyloid fibril diseases. The aim of the thesis is to deepen our understanding of its behavior and partitioning at interfaces, and to investigate its clustering. Classical atomistic molecular dynamics simulations were performed for phenylalanine and three other aromatic molecules which chemical structure is derived from it - phenylglycine, phenylacetic acid and tyrosine. Molecules are simulated at both water-air and at water-DPPC-air interfaces. Phenylalanine, phenylglycine and phenylacetic acid demonstrate surface activity at the water-air interface, whereas tyrosine is not surface active. All molecules interact with the lipid monolayer at the water-DPPC-air interface but only phenylalanine penetrates deep into the monolayer. Formation of transient clusters is observed in the interfacial regions, mostly for phenylalanine. Powered by TCPDF (www.tcpdf.org)

The aim of the thesis is to examine plasma-wall interaction using computer modeling. Tokamak- relevant plasma conditions are simulated using the particle-in-cell model family SPICE working in three or two dimensions. SPICE model was upgraded with a parallel Poisson equation solver and a heat equation solver module. Plasma simulation aimed at synthetic Langmuir probe measurements were performed. First set considered a flush-mounted probe and the effect of variable magnetic field angle was studied with aim to compare existing probe data evaluation techniques and assess their operational space, in which the plasma parameters estimation via fit to the current-voltage characteristic is accurate. Second simulation set studied a protruding probe pin. Effective collecting area of such probe was investigated with intentions of density measurement collection. This area was found to be influenced by a combination of two factors. First, the density dampening inside the magnetic pre-sheath of the probe head, and the second, the extension of the area caused by Larmor rotation. A comparison with experimental results obtained at COMPASS tokamak was was performed, confirming these results. Keywords Langmuir probe, simulation, particle-in-cell, tokamak, Poisson equation, COMPASS 1

The subject of the master thesis is the extension of the measurement of plasma para- meters by the Langmuir probe in a system with a planar magnetron and a hollow cathode operating in pulse mode. The main tasks are to modify the measuring circuit to increase the maximum probe current and to put the USB oscilloscope into operation for data collection with higher resolution and higher sampling rate. Furthermore, the function of the entire device will be verified using test circuits and also by measuring the probe characteristics in discharges in a system with a magnetron and a hollow cathode in both continuous and pulse mode. 1