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1	Pyridinium Bisretinoids: Synthesis and Photoactivated Cytotoxicity Gao, Junping 19 December 2007 (has links) (PDF) This thesis discusses pyridinium bisretinoid compounds (PBRs), which were prepared for two purposes: 1) to use them as standards for detection of novel fluorophores in human RPE cells, which may be involved in age-related macular degeneration (AMD), and 2) to use them in the development of a targeted and triggered drug delivery system for cancer therapy. We prepared a selection of PBRs using a one-pot biomimetic method; synthesis, mechanisms for formation, and characterization of these compounds is described. We also explored the photoreactivity of three novel PBR compounds and found that these PBRs form oxidation products under blue-light irradiation. The photoinduced cytotoxity of A2P and A2EE was examined in HL-60 cells. Results from this work suggest that the PBRs presented have the potential to be involved in AMD and to be developed into a targeted and triggered drug delivery system for cancer therapy. pyridinium bisretinoid age-related macular degeneration AMD blue-light irradiation cytotoxicity Biochemistry Chemistry
2	Photocatalytic nanocomposites for degradation of organic pollutants in water under visible light Malefane, Mope Edwin 11 1900 (has links) Heterojunctions were generated between tungsten trioxide and tetraphenyl porphyrin with reduced graphene oxide or exfoliated graphite support for mineralisation of acid blue 25 dye under visible light radiation. Moreover, degradation of pharmaceuticals was conducted using p-n heterojunctions between WO3 and Co3O4 and a direct Z-scheme heterojunction between BiOI and Co3O4 prepared using in-situ method and solvothermal self-assembly method respectively. The synthesized materials were characterised using Raman, FTIR, SEM/EDS, TEM, XRD, TGA, BET, UV-Vis and PL techniques. UV-Vis, TOC and HPLC-QTOF-MS were used to study the degradation efficiency and pathway. Scavenger trapping experiments were conducted to propose the charge transfer mechanisms. The highest degradation efficiency (99 %) was achieved for the dye and the pharmaceuticals using visible light. The mineralisation ability of the fabricated nanomaterials was pH dependent with acidic conditions favouring the removal of the dye (pH 5) while alkaline conditions favoured the mineralisation of pharmaceuticals (pH 10 – 11). / Civil and Chemical Engineering Heterojunctions Metal oxide semiconductors Synergy Proposed charge transfer Total organic carbon Visible light irradiation Photocatalysis Dyes Pharmaceuticals Batch reactor set-up
3	Photoreactivity and Enhanced Toughness and Stability in Polysaccharide-Based Materials Using Metal Ion Coordination Haddad, Carina 29 August 2022 (has links) No description available. Chemistry Polymer Chemistry Polymers Biopolymer polysaccharide film material hydrogel chitosan pectin carrageenan alginate agarose vanadium iron iron oxides metal coordination photochemistry photoreaction photoreactivity light irradiation mechanical properties curcumin micelles.

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