The normal distribution is a commonly seen distribution in nature, education, and business. Data that are mounded or bell shaped are easily found across various fields of study. Although there is high utility with the normal distribution; often the full range can not be observed. The truncated normal distribution accounts for the inability to observe the full range and allows for inferring back to the original population. Depending on the amount of truncation, the truncated normal has several distinct shapes. A simulation study evaluating the performance of the maximum likelihood estimators and method of moment estimators is conducted and a comparison of performance is made. The α Likelihood Ratio Test (LRT) is derived for testing the null hypothesis of equal population means for truncated normal data. A simulation study evaluating the power of the LRT to detect absolute standardized differences between the two population means with small sample size was conducted and the power curves were approximated. Another simulation study evaluating the power of the LRT to detect absolute differences for testing the hypothesis with large unequal sample sizes was conducted. The α LRT was extended to a k population hypothesis test for equal population means. A simulation study examining the power of the k population LRT for detecting absolute standardized differences when one of the population means is different than the others was conducted and the power curve approximated. Stat~221 is the largest introductory statistics course at BYU serving about 4,500 students a year. Every section of Stat 221 shares common homework assignments and tests. This controls for confounding when making comparisons between sections. Historically grades have been thought to be bell shaped, but with grade inflation and other factors, the upper tail is lost because of the truncation at 100. It is reasonable to assume that grades follow a truncated normal distribution. Inference using the final grades should be done recognizing the truncation. Performance of the different Stat 221 sections was evaluated using the LRTs derived.

The focus of this work is the development of testing procedures for the existence of change-points in parametric hazard models of various types. Hazard functions and the related survival functions are common units of analysis for survival and reliability modeling. We develop a methodology to test for the alternative of a two-piece hazard against a simpler one-piece hazard. The location of the change is unknown and the tests are irregular due to the presence of the change-point only under the alternative hypothesis. Our approach is to consider the profile log-likelihood ratio test statistic as a process with respect to the unknown change-point. We then derive its limiting process and find the supremum distribution of the limiting process to obtain critical values for the test statistic. We first reexamine existing work based on Taylor Series expansions for abrupt changes in exponential data. We generalize these results to include Weibull data with known shape parameter. We then develop new tests for two-piece continuous hazard functions using local asymptotic normality (LAN). Finally we generalize our earlier results for abrupt changes to include covariate information using the LAN techniques. While we focus on the cases of no censoring, simple right censoring, and censoring generated by staggered-entry; our derivations reveal that our framework should apply to much broader censoring scenarios. / Ph. D.

A semeadora manual é uma ferramenta que, ainda nos dias de hoje, exerce um papel importante em diversos países do mundo que praticam a agricultura familiar e de conservação. Sua utilização é de grande importância devido a minimização do distúrbio do solo, exigências de trabalho no campo, maior produtividade sustentável entre outros fatores. De modo a avaliar e/ou comparar as semeadoras manuais existentes no mercado, diversos trabalhos têm sido realizados, porém considerando somente medidas de posição e dispersão. Neste trabalho é utilizada, como alternativa, uma metodologia para a comparação dos desempenhos das semeadoras manuais. Neste caso, estimou-se as probabilidades associadas a cada categoria de resposta e testou-se a hipótese de que essas probabilidades não variam para as semeadoras quando comparadas duas a duas, utilizando o teste da razão das verossimilhanças e o fator de Bayes nos paradigmas clássico e bayesiano, respectivamente. Por fim, as semeadoras foram agrupadas considerando, como medida de distância, a medida de divergência J-divergência na análise de agrupamento. Como ilustração da metodologia apresentada, são considerados os dados para a comparação de quinze semeadoras manuais de diferentes fabricantes analisados por Molin, Menegatti e Gimenez (2001) em que as semeadoras foram reguladas para depositarem exatamente duas sementes por golpe. Inicialmente, na abordagem clássica, foram comparadas as semeadoras que não possuíam valores nulos nas categorias de resposta, sendo as semeadoras 3, 8 e 14 as que apresentaram melhores comportamentos. Posteriormente, todas as semeadoras foram comparadas duas a duas, agrupando-se as categorias e adicionando as contantes 0,5 ou 1 à cada categoria de resposta. Ao agrupar categorias foi difícil a tomada de conclusões pelo teste da razão de verossimilhanças, evidenciando somente o fato da semeadora 15 ser diferente das demais. Adicionando 0,5 ou 1 à cada categoria não obteve-se, aparentemente, a formação de grupos distintos, como a semeadora 1 pelo teste diferiu das demais e apresentou maior frequência no depósito de duas sementes, o exigido pelo experimento agronômico, foi a recomendada neste trabalho. Na abordagem bayesiana, utilizou-se o fator de Bayes para comparar as semeadoras duas a duas, no entanto as conclusões foram semelhantes às obtidas na abordagem clássica. Finalmente, na análise de agrupamento foi possível uma melhor visualização dos grupos de semeadoras semelhantes entre si em ambas as abordagens, reafirmando os resultados obtidos anteriormente. / The manual planter is a tool that today still has an important role in several countries around the world, which practices family and conservation agriculture. The use of it has importance due to minimizing soil disturbance, labor requirements in the field, most sustainable productivity and other factors. In order to analyze and/or compare the commercial manual planters, several studies have been conducted, but considering only position and dispersion measures. This work presents an alternatively method for comparing the performance of manual planters. In this case, the probabilities associated with each category of response has estimated and the hypothesis that these probabilities not vary for planters when compared in pairs evaluated using the likelihood ratio test and Bayes factor in the classical and bayesian paradigms, respectively. Finally, the planters were grouped considering as a measure of distance, the divergence measure J-divergence in the cluster analysis. As an illustration of this methodology, the data from fifteen manual planters adjusted to deposit exactly two seeds per hit of different manufacturers analyzed by Molin, Menegatti and Gimenez (2001) were considered. Initially, in the classical approach, the planters without zero values in response categories were compared and the planters 3, 8 and 14 presents the better behavior. After, all the planters were compared in pairs, grouping categories and adding the constants 0,5 or 1 for each response category. Grouping categories was difficult making conclusions by the likelihood ratio test, only highlighting the fact that the planter 15 is different from others. Adding 0,5 or 1 for each category, apparently not obtained the formation of different groups, such as planter 1 which by the test differed from the others and presented more frequently the deposit of two seeds, required by agronomic experiment and recommended in this work. In the Bayesian approach, the Bayes factor was used to compare the planters in pairs, but the findings were similar to those obtained in the classical approach. Finally, the cluster analysis allowed a better idea of similar planters groups with each other in the both approaches, confirming the results obtained previously.

Current status data are usually obtained with a failure time variable T which is diffcult observed but can be determined to lie below or above a random monitoring time or inspection time t. In this work we consider bivariate current status data ${t,delta_1,delta_2}$ and assume we have some prior information of the bivariate failure time variables T1 and T2. Our main goal is to find an optimal inspection time for testing the relationship between T1 and T2.

The design of clinical trials is one of the important problems in medical statistics. Its main purpose is to determine the methodology and the sample size required of a testing study to examine the safety and efficacy of drugs. It is also a part of the Food and Drug Administration approval process. In this thesis, we first study the comparison of the efficacy of drugs in clinical trials. We focus on the two-sample comparison of proportions to investigate testing strategies based on two-stage design. The properties and advantages of the procedures from the proposed testing designs are demonstrated by numerical results, where comparison with the classical method is made under the same sample size. A real example discussed in Cardenal et al. (1999) is provided to explain how the methods may be used in practice. Some figures are also presented to illustrate the pattern changes of the power functions of these methods. In addition, the proposed procedure is also compared with the Pocock (1997) and O¡¦Brien and Fleming (1979) tests based on the standardized statistics. In the second part of this work, the operating room scheduling problem is considered, which is also important in medical studies. The national health insurance system has been conducted more than ten years in Taiwan. The Bureau of National Health Insurance continues to improve the national health insurance system and try to establish a reasonable fee ratio for people in different income ranges. In accordance to the adjustment of the national health insurance system, hospitals must pay more attention to control the running cost. One of the major hospital's revenues is generated by its surgery center operations. In order to maintain financial balance, effective operating room management is necessary. For this topic, this study focuses on the model fitting of operating times and operating room scheduling. Log-normal and mixture log-normal distributions are identified to be acceptable statistically in describing these operating times. The procedure is illustrated through analysis of thirteen operations performed in the gynecology department of a major teaching hospital in southern Taiwan. The best fitting distributions are used to evaluate performances of some operating combinations on daily schedule, which occurred in real data. The fitted distributions are selected through certain information criteria and bootstrapping the log-likelihood ratio test. Moreover, we also classify the operations into three different categories as well as three stages for each operation. Then based on the classification, a strategy of efficient scheduling is proposed. The benefits of rescheduling based on the proposed strategy are compared with the original scheduling observed.

This thesis investigates particular topics in advanced motion control of two distinct mechanical systems: human-like motion control of redundant robot manipulators and advanced sensing and control for energy-efficient operation of electromagnetic devices. Control of robot manipulators for human-like motions has been one of challenging topics in robot control for over half a century. The first part of this thesis considers methods that exploits robot manipulators??? degrees of freedom for such purposes. Jacobian transpose control law is investigated as one of the well-known controllers and sufficient conditions for its universal convergence are derived by using concepts of ???stability on a manifold??? and ???transferability to a sub-manifold???. Firstly, a modification on this method is proposed to enhance the rectilinear trajectory of the robot end-effector. Secondly, an abridged Jacobian controller is proposed that exploits passive control of joints to reduce the attended degrees of freedom of the system. Finally, the application of minimally-attended controller for human-like motion is introduced. Electromagnetic (EM) access control systems are one of growing electronic systems which are used in applications where conventional mechanical locks may not guarantee the expected safety of the peripheral doors of buildings. In the second part of this thesis, an intelligent EM unit is introduced which recruits the selfsensing capability of the original EM block for detection purposes. The proposed EM device optimizes its energy consumption through a control strategy which regulates the supply to the system upon detection of any eminent disturbance. Therefore, it draws a very small current when the full power is not needed. The performance of the proposed control strategy was evaluated based on a standard safety requirement for EM locking mechanisms. For a particular EM model, the proposed method is verified to realize a 75% reduction in the power consumption.

A semeadora manual é uma ferramenta que, ainda nos dias de hoje, exerce um papel importante em diversos países do mundo que praticam a agricultura familiar e de conservação. Sua utilização é de grande importância devido a minimização do distúrbio do solo, exigências de trabalho no campo, maior produtividade sustentável entre outros fatores. De modo a avaliar e/ou comparar as semeadoras manuais existentes no mercado, diversos trabalhos têm sido realizados, porém considerando somente medidas de posição e dispersão. Neste trabalho é utilizada, como alternativa, uma metodologia para a comparação dos desempenhos das semeadoras manuais. Neste caso, estimou-se as probabilidades associadas a cada categoria de resposta e testou-se a hipótese de que essas probabilidades não variam para as semeadoras quando comparadas duas a duas, utilizando o teste da razão das verossimilhanças e o fator de Bayes nos paradigmas clássico e bayesiano, respectivamente. Por fim, as semeadoras foram agrupadas considerando, como medida de distância, a medida de divergência J-divergência na análise de agrupamento. Como ilustração da metodologia apresentada, são considerados os dados para a comparação de quinze semeadoras manuais de diferentes fabricantes analisados por Molin, Menegatti e Gimenez (2001) em que as semeadoras foram reguladas para depositarem exatamente duas sementes por golpe. Inicialmente, na abordagem clássica, foram comparadas as semeadoras que não possuíam valores nulos nas categorias de resposta, sendo as semeadoras 3, 8 e 14 as que apresentaram melhores comportamentos. Posteriormente, todas as semeadoras foram comparadas duas a duas, agrupando-se as categorias e adicionando as contantes 0,5 ou 1 à cada categoria de resposta. Ao agrupar categorias foi difícil a tomada de conclusões pelo teste da razão de verossimilhanças, evidenciando somente o fato da semeadora 15 ser diferente das demais. Adicionando 0,5 ou 1 à cada categoria não obteve-se, aparentemente, a formação de grupos distintos, como a semeadora 1 pelo teste diferiu das demais e apresentou maior frequência no depósito de duas sementes, o exigido pelo experimento agronômico, foi a recomendada neste trabalho. Na abordagem bayesiana, utilizou-se o fator de Bayes para comparar as semeadoras duas a duas, no entanto as conclusões foram semelhantes às obtidas na abordagem clássica. Finalmente, na análise de agrupamento foi possível uma melhor visualização dos grupos de semeadoras semelhantes entre si em ambas as abordagens, reafirmando os resultados obtidos anteriormente. / The manual planter is a tool that today still has an important role in several countries around the world, which practices family and conservation agriculture. The use of it has importance due to minimizing soil disturbance, labor requirements in the field, most sustainable productivity and other factors. In order to analyze and/or compare the commercial manual planters, several studies have been conducted, but considering only position and dispersion measures. This work presents an alternatively method for comparing the performance of manual planters. In this case, the probabilities associated with each category of response has estimated and the hypothesis that these probabilities not vary for planters when compared in pairs evaluated using the likelihood ratio test and Bayes factor in the classical and bayesian paradigms, respectively. Finally, the planters were grouped considering as a measure of distance, the divergence measure J-divergence in the cluster analysis. As an illustration of this methodology, the data from fifteen manual planters adjusted to deposit exactly two seeds per hit of different manufacturers analyzed by Molin, Menegatti and Gimenez (2001) were considered. Initially, in the classical approach, the planters without zero values in response categories were compared and the planters 3, 8 and 14 presents the better behavior. After, all the planters were compared in pairs, grouping categories and adding the constants 0,5 or 1 for each response category. Grouping categories was difficult making conclusions by the likelihood ratio test, only highlighting the fact that the planter 15 is different from others. Adding 0,5 or 1 for each category, apparently not obtained the formation of different groups, such as planter 1 which by the test differed from the others and presented more frequently the deposit of two seeds, required by agronomic experiment and recommended in this work. In the Bayesian approach, the Bayes factor was used to compare the planters in pairs, but the findings were similar to those obtained in the classical approach. Finally, the cluster analysis allowed a better idea of similar planters groups with each other in the both approaches, confirming the results obtained previously.

No description available.

System testing is very time-consuming and costly, especially for complex high-cost and high-reliability systems. For this reason, the number of failures needed for the developmental phase of system testing should be relatively small in general. To assess the reliability growth of a repairable system, the generalized confidence interval and the modified signed log-likelihood ratio test for the scale parameter of the power-law process are studied concerning incomplete failure data. Specifically, some recorded failure times in the early developmental phase of system testing cannot be observed; this circumstance is essential to establish a warranty period or determine a maintenance phase for repairable systems. For the proposed generalized confidence interval, we have found that this method is not biased estimates which can be seen from the coverage probabilities obtained from this method being close to the nominal level 0.95 for all levels of γ and β. When the performance of the proposed method and the existing method are compared and validated regarding average widths, the simulation results show that the proposed method is superior to another method due to shorter average widths when the predetermined number of failures is small. For the proposed modified signed log-likelihood ratio test, we have found that this test performs well in controlling type I errors for complete failure data, and it has desirable powers for all parameters configurations even for the small number of failures. For incomplete failure data, the proposed modified signed log-likelihood ratio test is preferable to the signed log-likelihood ratio test in most situations in terms of controlling type I errors. Moreover, the proposed test also performs well when the missing ratio is up to 30% and n > 10. In terms of empirical powers, the proposed modified signed log-likelihood ratio test is superior to another test for most situations. In conclusion, it is quite clear that the proposed methods, the generalized confidence interval, and the modified signed log-likelihood ratio test, are practically useful to save business costs and time during the developmental phase of system testing since the only small number of failures is required to test systems, and it yields precise results.

Bien que les champignons soient régulièrement utilisés comme modèle d'étude des systèmes eucaryotes, leurs relations phylogénétiques soulèvent encore des questions controversées. Parmi celles-ci, la classification des zygomycètes reste inconsistante. Ils sont potentiellement paraphylétiques, i.e. regroupent de lignées fongiques non directement affiliées. La position phylogénétique du genre Schizosaccharomyces est aussi controversée: appartient-il aux Taphrinomycotina (précédemment connus comme archiascomycetes) comme prédit par l'analyse de gènes nucléaires, ou est-il plutôt relié aux Saccharomycotina (levures bourgeonnantes) tel que le suggère la phylogénie mitochondriale? Une autre question concerne la position phylogénétique des nucléariides, un groupe d'eucaryotes amiboïdes que l'on suppose étroitement relié aux champignons. Des analyses multi-gènes réalisées antérieurement n'ont pu conclure, étant donné le choix d'un nombre réduit de taxons et l'utilisation de six gènes nucléaires seulement. Nous avons abordé ces questions par le biais d'inférences phylogénétiques et tests statistiques appliqués à des assemblages de données phylogénomiques nucléaires et mitochondriales. D'après nos résultats, les zygomycètes sont paraphylétiques (Chapitre 2) bien que le signal phylogénétique issu du jeu de données mitochondriales disponibles est insuffisant pour résoudre l'ordre de cet embranchement avec une confiance statistique significative. Dans le Chapitre 3, nous montrons à l'aide d'un jeu de données nucléaires important (plus de cent protéines) et avec supports statistiques concluants, que le genre Schizosaccharomyces appartient aux Taphrinomycotina. De plus, nous démontrons que le regroupement conflictuel des Schizosaccharomyces avec les Saccharomycotina, venant des données mitochondriales, est le résultat d'un type d'erreur phylogénétique connu: l'attraction des longues branches (ALB), un artéfact menant au regroupement d'espèces dont le taux d'évolution rapide n'est pas représentatif de leur véritable position dans l'arbre phylogénétique. Dans le Chapitre 4, en utilisant encore un important jeu de données nucléaires, nous démontrons avec support statistique significatif que les nucleariides constituent le groupe lié de plus près aux champignons. Nous confirmons aussi la paraphylie des zygomycètes traditionnels tel que suggéré précédemment, avec support statistique significatif, bien que ne pouvant placer tous les membres du groupe avec confiance. Nos résultats remettent en cause des aspects d'une récente reclassification taxonomique des zygomycètes et de leurs voisins, les chytridiomycètes. Contrer ou minimiser les artéfacts phylogénétiques telle l'attraction des longues branches (ALB) constitue une question récurrente majeure. Dans ce sens, nous avons développé une nouvelle méthode (Chapitre 5) qui identifie et élimine dans une séquence les sites présentant une grande variation du taux d'évolution (sites fortement hétérotaches - sites HH); ces sites sont connus comme contribuant significativement au phénomène d'ALB. Notre méthode est basée sur un test de rapport de vraisemblance (likelihood ratio test, LRT). Deux jeux de données publiés précédemment sont utilisés pour démontrer que le retrait graduel des sites HH chez les espèces à évolution accélérée (sensibles à l'ALB) augmente significativement le support pour la topologie « vraie » attendue, et ce, de façon plus efficace comparée à d'autres méthodes publiées de retrait de sites de séquences. Néanmoins, et de façon générale, la manipulation de données préalable à l'analyse est loin d’être idéale. Les développements futurs devront viser l'intégration de l'identification et la pondération des sites HH au processus d'inférence phylogénétique lui-même. / Despite the popularity of fungi as eukaryotic model systems, several questions on their phylogenetic relationships continue to be controversial. These include the classification of zygomycetes that are potentially paraphyletic, i.e. a combination of several not directly related fungal lineages. The phylogenetic position of Schizosaccharomyces species has also been controversial: do they belong to Taphrinomycotina (previously known as archiascomycetes) as predicted by analyses with nuclear genes, or are they instead related to Saccharomycotina (budding yeast) as in mitochondrial phylogenies? Another question concerns the precise phylogenetic position of nucleariids, a group of amoeboid eukaryotes that are believed to be close relatives of Fungi. Previously conducted multi-gene analyses have been inconclusive, because of limited taxon sampling and the use of only six nuclear genes. We have addressed these issues by assembling phylogenomic nuclear and mitochondrial datasets for phylogenetic inference and statistical testing. According to our results zygomycetes appear to be paraphyletic (Chapter 2), but the phylogenetic signal in the available mitochondrial dataset is insufficient for resolving their branching order with statistical confidence. In Chapter 3 we show with a large nuclear dataset (more than 100 proteins) and conclusive supports that Schizosaccharomyces species are part of Taphrinomycotina. We further demonstrate that the conflicting grouping of Schizosaccharomyces with budding yeasts, obtained with mitochondrial sequences, results from a phylogenetic error known as long-branch attraction (LBA, a common artifact that leads to the regrouping of species with high evolutionary rates irrespective of their true phylogenetic positions). In Chapter 4, using again a large nuclear dataset we demonstrate with significant statistical support that nucleariids are the closest known relatives of Fungi. We also confirm paraphyly of traditional zygomycetes as previously suggested, with significant support, but without placing all members of this group with confidence. Our results question aspects of a recent taxonomical reclassification of zygomycetes and their chytridiomycete neighbors (a group of zoospore-producing Fungi). Overcoming or minimizing phylogenetic artifacts such as LBA has been among our most recurring questions. We have therefore developed a new method (Chapter 5) that identifies and eliminates sequence sites with highly uneven evolutionary rates (highly heterotachous sites, or HH sites) that are known to contribute significantly to LBA. Our method is based on a likelihood ratio test (LRT). Two previously published datasets are used to demonstrate that gradual removal of HH sites in fast-evolving species (suspected for LBA) significantly increases the support for the expected ‘true’ topology, in a more effective way than comparable, published methods of sequence site removal. Yet in general, data manipulation prior to analysis is far from ideal. Future development should aim at integration of HH site identification and weighting into the phylogenetic inference process itself.