The main purpose of this thesis is to combine modified GML algorithm with 2-D simulated annealing for estimation of signal arrival time in the UWB systems.In a dense multipath environment, the generalized maximum-likelihood (GML) algorithm can be used for the time-of-arrival (TOA) estimation. Nevertheless, the GML algorithm usually takes a long period of time, and sometimes fails to converge. Hence, a modified GML (MGML) algorithm is investigated. Two threshold parameters need to be determined in using the estimation algorithm. One threshold is to decide the arrival time range of estimated path, and the other, an amplitude threshold, is to judge whether the estimated path is true. Generally, the decision rule of thresholds may be based on the minimum error probability, which is defined as the sum of false alarm probability and miss probability. To mitigate the effects from noise and dense multipath interference, and to reduce the computational complexity of the algorithm, a method of threshold settings based on the minimum root mean square error (RMSE) criteria is discussed. In this scheme, the RMSE value for each candidate threshold pair in an appropriate region is computed. Constructing an accurate RMSE table and performing a full-scale grid search of adequate threshold settings can be very time-consuming. A 2-D simulated annealing process is adopted for finding the best pair of thresholds for use in the modified GML algorithm. The simulated annealing, different from the gradient descent, can avoid trapping into a local minimum in finding the best threshold pair. The resulting threshold pair makes the modified GML algorithm become more efficient in estimating the signal arrival time with an automatic search manner. Simulation results show that the proposed scheme can achieve better performance than the grid search approaches in UWB environments.

Univ. der Bundeswehr, Diss.--München, 2003.

This thesis proposes a new spatial multivariate count model to jointly analyze the traffic crash-related counts of pedestrians and bicyclists by injury severity. The modeling framework is applied to predict injury counts at a Census tract level, based on crash data from Manhattan, New York. The results highlight the need to use a multivariate modeling system for the analysis of injury counts by road-user type and injury severity level, while also accommodating spatial dependence effects in injury counts. / text

In biomedical research and lifetime data analysis, the comparison of two hazard functions usually plays an important role in practice. In this thesis, we consider the standard independent two-sample framework under right censoring. We construct efficient and useful confidence intervals for the ratio and difference of two hazard functions using smoothed empirical likelihood methods. The empirical log-likelihood ratio is derived and its asymptotic distribution is a chi-squared distribution. Furthermore, the proposed method can be applied to medical diagnosis research. Simulation studies show that the proposed EL confidence intervals have better performance in terms of coverage accuracy and average length than the traditional normal approximation method. Finally, our methods are illustrated with real clinical trial data. It is concluded that the empirical likelihood methods provide better inferential outcomes.

Ausgehend vom klassischen linearen Modell werden Regressionsmethoden für Datenstrukturen dargestellt, bei denen die Standardannahmen (Unabhängigkeit, normalverteilte Fehler und konstante Varianz) nicht erfüllt sind. Läßt man die Responsevariable aus einer Exponentialfamilie zu, so erhält man die Klasse generalisierter linearer Modelle (GLM) . Dies erlaubt, den Erwartungswert von verschiedensten stetigen und diskreten Responsevariablen (z .B. Anteile, Häufigkeiten, etc.) über eine fixe Kovariatenstruktur zu modellieren. Hebt man zusatzlich die Notwendigkeit auf, eine Verteilung aus Exponentialfamilien spezifizieren zu müssen, erhält man Quasi-Likelihood Modelle, bei denen nur mehr eine Beziehung zwischen Erwartungswert und Varianz festgelegt werden muß. Die Berücksichtigung einer Korrelationsstruktur führt zu verallgemeinerten Schätzgleichungen, d.h. es können auch Longitudinaldaten ohne besondere Verteilungsannahmen analysiert werden. Ziel der Arbeit ist es, diese Methoden und ihre statistischen Eigenschaften vorzustellen und anhand eines Beispiels (Überdispersion bei wiederholt gemessenen binomialen Anteilen) ihre Bedeutung in der biometrischen Praxis zu illustrieren. (Autorenref.) / Series: Forschungsberichte / Institut für Statistik

In parametrized continuous state-space models, one can obtain estimates of the likelihood of the data for fixed parameters via the Sequential Monte Carlo methodology. Unfortunately, even if the likelihood is continuous in the parameters, the estimates produced by practical particle filters are not, even when common random numbers are used for each filter. This is because the same resampling step which drastically reduces the variance of the estimates also introduces discontinuities in the particles that are selected across filters when the parameters change. When the state variables are univariate, a method exists that gives an estimator of the log-likelihood that is continuous in the parameters. We present a non-trivial generalization of this method using tree-based o(N²) (and as low as O(N log N)) resampling schemes that induce significant correlation amongst the selected particles across filters. In turn, this reduces the variance of the difference between the likelihood evaluated for different values of the parameters and the resulting estimator is considerably smoother than naively running the filters with common random numbers. Importantly, in practice our methods require only a change to the resample operation in the SMC framework without the addition of any extra parameters and can therefore be used for any application in which particle filters are already used. In addition, excepting the optional use of interpolation in the schemes, there are no regularity conditions for their use although certain conditions make them more advantageous. In this thesis, we first introduce the relevant aspects of the SMC methodology to the task of likelihood estimation in continuous state-space models and present an overview of work related to the task of smooth likelihood estimation. Following this, we introduce theoretically correct resampling schemes that cannot be implemented and the practical tree-based resampling schemes that were developed instead. After presenting the performance of our schemes in various applications, we show that two of the schemes are asymptotically consistent with the theoretically correct but unimplementable methods introduced earlier. Finally, we conclude the thesis with a discussion.

The mean residual life (MRL) function is an important function in survival analysis, actuarial science, economics and other social sciences and reliability for characterizing lifetime. Different methods have been proposed for doing inference on the MRL but their coverage probabilities for small sample sizes are not good enough. In this thesis we apply the empirical likelihood method and carry out a simulation study of the MRL function using different statistical distributions. The simulation study does a comparison of the empirical likelihood method and the normal approximation method. The comparisons are based on the average lengths of confidence intervals and coverage probabilities. We also did comparisons based on median lengths of confidence intervals for the MRL. We found that the empirical likelihood method gives better coverage probability and shorter confidence intervals than the normal approximation method for almost all the distributions that we considered. Applying the two methods to real data we also found that the empirical likelihood method gives thinner pointwise confidence bands.

Diagnostic testing is essential to distinguish non-diseased individuals from diseased individuals. More accurate tests lead to improved treatment and thus reduce medical mistakes. The sensitivity and specificity are two important measurements for the diagnostic accuracy of a diagnostic test. When the test results are continuous, it is of interest to construct a confidence interval for the sensitivity at a fixed level of specificity for the test. In this thesis, we propose three empirical likelihood intervals for the sensitivity. Simulation studies are conducted to compare the empirical likelihood based confidence intervals with the existing normal approximation based confidence interval. Our studies show that the new intervals had better coverage probability than the normal approximation based interval in most simulation settings.

In biomedical research and lifetime data analysis, the comparison of two hazard functions usually plays an important role in practice. In this thesis, we consider the standard independent two-sample framework under right censoring. We construct efficient and useful confidence intervals for the ratio and difference of two hazard functions using smoothed empirical likelihood methods. The empirical log-likelihood ratio is derived and its asymptotic distribution is a chi-squared distribution. Furthermore, the proposed method can be applied to medical diagnosis research. Simulation studies show that the proposed EL confidence intervals have better performance in terms of coverage accuracy and average length than the traditional normal approximation method. Finally, our methods are illustrated with real clinical trial data. It is concluded that the empirical likelihood methods provide better inferential outcomes.

In this thesis, we study two independent samples under right censoring. Using a smoothed empirical likelihood method, we investigate the difference of quantiles in the two samples and construct the pointwise confidence intervals from it as well. The empirical log-likelihood ratio is proposed and its asymptotic limit is shown as a chi-squared distribution. In the simulation studies, in terms of coverage accuracy and average length of confidence intervals, we compare the empirical likelihood and the normal approximation method. It is concluded that the empirical likelihood method has a better performance. At last, a real clinical trial data is used for the purpose of illustration. Numerical examples to illustrate the efficacy of the method are presented.