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Higher-order functional languages and intensional logicRondogiannis, Panagiotis 10 April 2015 (has links)
Graduate
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Protein side-chain placement using CLPSwain, Martin T. January 2001 (has links)
Constraint logic programming (CLP) techniques can be used in protein side-chain placement, an important sub-task in comparative modelling. In a simple formulation values for domain variables represent rotamer side-chain conformations, and constraints represent atomic clashes. These constraints can be visualised using a "rotamer contact map", and observations made with this visualisation tool have been used to develop a strategy that overcomes limitations present in CLP caused by over-constrained residues. Null rotamers provide a mechanism that can automatically identify over-constrained residues. The use of null rotamers makes possible an iterative modelling strategy where, at each iteration, a CLP program is generated automatically; each program representing successively tighter packing constraints corresponding to larger atomic radii. Different CLP enumeration heuristics have been evaluated for use with this side-chain placement method, and it has been tested with several different rotamer libraries; a backbone-dependent rotamer library, when used with first-fail enumeration heuristics, was shown to be the most successful. Side-chain conformations predicted by this CLP method compare favourably against those predicted using other side-chain placement methods. The CLP method has been applied to two modelling problems. The first involved building models of class II MHC molecules in order to increase the utility of a peptide threading program. This program uses an allele's known or modelled 3D structure with a heuristic scoring function to predict peptides that are likely to bind to it - thus using CLP to model class II MHC alleles increases the program's utility. The second application used the CLP method to build structures of ribosome inactivating proteins (RIPs). These models were built using CLP together with comparative modelling approaches, and a model of bouganin, a recently identified wild RIF protein, has been built to help design engineered therapeutic proteins.
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A message driven or-parallel logic architectureDelgado Rannauro, Sergio A. January 1989 (has links)
No description available.
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A methodology and a tool for the formalisation and representation of 'common sense' (naive physical) knowledgeCunningham, J. January 1985 (has links)
No description available.
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Integrity constraints in deductive databasesDas, Subrata Kumar January 1990 (has links)
No description available.
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Implementation of committed choice logic languages on shared memory multiprocessorsCrammond, James Alexander January 1988 (has links)
No description available.
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Coupled resolution engines for programming knowledge based systems in logicTaylor, Hamish January 1989 (has links)
No description available.
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Prolog and expert systemsDavies, Peter Leslie January 1987 (has links)
The first part of the thesis provides an introduction to the logic programming language Prolog and some areas of current research. The use of compilation to make Prolog faster and more efficient is studied and a modified representation for complex structures is presented. Two programming tools are also presented. The second part of the thesis focuses on one problem which arises when implementing an Expert System using Prolog. A practical three-valued Prolog implementation is described. An interpreter accepts three-valued formulae and converts these into a Prolog representation. Formulae are in clausal form which allows disjunctive conclusions to rules. True and false formulae are stated explicitly and therefore the interpreter is able to perform useful consistency checks when information is added to the data base.
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Sequentialization of logic programs /Treitel, Richard James. January 1900 (has links)
Thesis (Ph. D.)--Stanford University, 1986. / "September 1986." "This work was partially supported by the Office of Naval Research under contracts number N00014-81-K-0303 and N00014-81-K-0004, by the National Institutes of Health under grant number 5P41 RR 00785, and by the Defense Advanced Research Projects Agency under contract number N00039-86-C-0033"--P. vi. Bibliography: p. 160-167.
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Towards next generation logic programming systems /Bansal, Ajay, January 2007 (has links)
Thesis (Ph.D.)--University of Texas at Dallas, 2007. / Includes vita. Includes bibliographical references (leaves 105-110)
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