A curcumina possui uma grande variedade de propriedades benéficas para a saúde humana. Devido a este fato, a indústria alimentícia tem aumentado a aplicação deste bioativo como aromatizante, conservante e aditivo para substituição dos corantes amarelos artificiais. No entanto, incorporar a curcumina em formulações alimentícias pode ser problemático porque sua molécula hidrofóbica tem baixa solubilidade em água e é muito sensível à luz. Os métodos de encapsulação em nanoemulsões podem tornar viável a proteção do curcuminoide, bem como permitir sua dispersibilidade em água. O objetivo do presente trabalho de Mestrado foi produzir nanoemulsões encapsulando curcumina pelo método do ponto de inversão da emulsão (EIP, emulsion inversion point), determinando parâmetros de operação que viabilizem um futuro escalonamento do processo e incorporação das dispersões em sorvete de massa sabor abacaxi. Os parâmetros de produção foram ajustados como: tipo e concentração de tensoativo (razão SOR), concentração de óleo de soja, tipo e concentração de cosolvente, tipo de impelidor/ velocidade de agitação e vazão de entrada da fase aquosa. As porcentagens de curcumina encapsulada foram 0,03, 0,07 e 0,10%. Dentre estas, a concentração de 0,07% foi a mais viável para a aplicação no sorvete de massa sabor abacaxi, por apresentar melhor distribuição de tamanho de gotícula (diâmetro hidrodinâmico), não apresentar variação significativa de oxidação lipídica, boa manutenção da curcumina encapsulada (70%) e, consequentemente, a sua cor, apresentando maior estabilidade do parâmetro TCD por um período de 60 dias. Os testes reológicos não mostraram mudança na estrutura de nanoemulsões com a encapsulação de curcumina. Das formulações testadas para sorvete de abacaxi contendo curcumina, a formulação usando nanoemulsões substituindo 50% da mistura comercial (B) teve uma maior aceitação de cor, sabor e aroma, sendo compatível com a formulação comercial (A). Esta formulação (B) e aquela com substituição completa da mistura comercial (C) apresentaram uma maior estabilidade quanto à manutenção da cor durante o período do estudo. Os testes reológicos não mostraram diferença estrutural entre as formulações testadas para sorvete de abacaxi. Indicando que não houve influência nas características estruturais do sorvete contendo nanoemulsão com curcumina encapsulada. / Curcumin has several beneficial properties and the food industry has been trying to increase the use of curcumin as flavoring, conservant or as a replacer of artificial yellow dyes. However, incorporating curcumin can be difficult due to its hydrophobicity and low water solubility, as well as high sensitivity to light. Encapsulation in nanoemulsions can be an interesting technological alternative to encapsulate and protect the curcuminoid. The objective of this study was to produce nanoemulsions encapsulating curcumin by the low-energy method EIP (emulsion inversion point), determining operating parameters that enable a future escalation of the process and incorporation of dispersions in pineapple ice cream. The production parameters were adjusted as: type and concentration of surfactante, soybean oil concentration, type and concentration of cosolvent, impeller type/speed stirring and flow of the aqueous phase. The percentages of encapsulated curcumin were 0.03, 0.07 and 0.10%. The concentration of 0.07% was the most viable for application in pineapple ice cream, for presenting better distribution of droplet size (hydrodynamic diameter), do not presente of significant changes in lipid oxidation, good maintenance of encapsulated curcumin (70%) and therefore its color, with greater stability of the TCD parameter for a period of 60 days. The rheological tests showed no change in the nanoemulsions structure with encapsulating curcumin. Among the formulations tested for pineapple ice cream incorporating encapsulated curcumin, the formulation using nanoemulsions replacing 50% of the commercial mixture (B) had a better acceptance of color, flavor and aroma and it is compatible with the commercial formulation (A). This formulation (B) and that with complete replacement of the commercial mixture (C) had a higher stability and maintenance of color during the storage period. The rheological tests showed no structural difference between the formulations tested for pineapple ice cream, indicating no influence on the structural characteristics of the ice cream containing nanoemulsion with encapsulated curcumin.

This thesis presents a wireless communication system for intra-satellite communication based on Bluetooth Low Energy technology, which can have many benefits regarding the design and operation of satellites. The proposed design based on the nRF53832 chip from Nordic Semiconductor is described, followed by the results of several tests regarding the most important design criteria for its application in small satellites. The tested aspects include the power consumption of the wireless module in different operation modes, which is sufficiently low for the application even in small satellites. Signal strength measurements for various output power settings and obstacles show that reliable communication is possible in a satellite mockup. No packet error was detected, and latencies of less than 30 ms combined with achievable data rates between 200 and 700 kbps should be sufficient for most CubeSat satellites. Additionally, details are given to successfully integrate the chip with existing satellite subsystems. A code library is provided to simplify the communication between the modules, and a concept of a redundant system is established to increase the reliability for critical satellite subsystems. The overall assessment of the technology suggests that the presented system is suitable for in-orbit deployment with the Aalto-3 satellite (currently being developed at Aalto University), which will provide further validation of the technology.

In this thesis three studies of the geometric structure of the (110) surface of single crystal rutile TiO2 are presented. Firstly, quantitative low energy electron diffraction (LEED-IV) data acquired from TiO2(110)(1x1) are reanalysed to confirm the integrity of the previously reported optimized geometries by performing structural optimisation as a function of depth into the selvedge. The second study addresses the geometry of the x-linked (1x2) reconstruction of the same surface. Again, LEED-IV data are analysed to quantitatively determine the surface structure. Part of this effort involved substantial development of the code (SATLEED) employed for simulating the experimental data, to allow simultaneous optimisation of more than one surface termination. In contrast to recent scanning probe work, the analysis indicates that the surface consists of two differently relaxed Ti2O3 added rows. The last study concerns ab initio calculations of the structure of benzoate on TiO2(110)(1x1). Of particular interest is the impact of surface coverage on the orientation of the benzene ring. It is predicted that the benzene ring twists and tilts away from high symmetry with increasing coverage due to adsorbate-adsorbate interactions. No evidence is found to support the formation of benzoate dimers or trimers, as was concluded in earlier experimental work.

This diplomate thesis will have two parts, theoretical and practical. The first part of this diplomate thesis contains short analyse of consumption and prices of energy which we need on heating. In the next part will be described ecological (low -- energy) housing in general, which would have protect the environment. The second part will be about charkteristics and criterias, fundamental elements of low -- energy housing and main aims of low -- energy housing. The following part of this thesis will contain information about energy balance of houses, concretely which heat gains and losses exit. For construction of these buildings is very important building -- energy conception of building and technical arrangement of houses. The last part will be about the contemporary trend of ecological building -- up in the Czech Republic. This thesis will continel in practical part, on research of the Czech market. Concretely market research from the look of consumers, what is their demand, what lead them to build low -- energy houses, who is the typical consumer, etc. Further from the look of designer and building societies. The method will be questionnaire inqeury. Purpose of this diplomate thesis will be to valorize the situation about low -- energy housing on the Czech market.

Coarse-grained fabrics are comprised of multi-bit configurable logic blocks and configurable interconnect. This work is focused on area and energy optimization techniques for coarse-grained reconfigurable fabric architectures. In this work, a variety of design techniques have been explored to improve the utilization of computational resources and increase energy savings. This includes splitting, folding, multi-level vertical interconnect. In addition to this, I have also studied fully connected homogeneous and heterogeneous architectures, and 3D architecture. I have also examined some of the hybrid strategies of computation unit’s arrangements. In order to perform energy and area analysis, I selected a set of signal and image processing benchmarks from MediaBench suite. I implemented various fabric architectures on 90nm ASIC process from Synopsys. Results show area improvement with energy savings as compared to baseline architecture.

abstract: Wearable technology has brought in a rapid shift in the areas of healthcare and lifestyle management. The recent development and usage of wearable devices like smart watches has created significant impact in areas like fitness management, exercise tracking, sleep quality assessment and early diagnosis of diseases like asthma, sleep apnea etc. This thesis is dedicated to the development of wearable systems and algorithms to fulfill unmet needs in the area of cardiorespiratory monitoring. First, a pneumotach based flow sensing technique has been developed and integrated into a face mask for respiratory profile tracking. Algorithms have been developed to convert the pressure profile into respiratory flow rate profile. Gyroscope-based correction is used to remove motion artifacts that arise from daily activities. By using Principal Component Analysis, the follow-up work established a unique respiratory signature for each subject based on the flow profile and lung parameters computed using the wearable mask system. Next, wristwatch devices to track transcutaneous gases like oxygen (TcO2) and carbon dioxide (TcCO2), and oximetry (SpO2) have been developed. Two chemical sensing approaches have been explored. In the first approach, miniaturized low-cost commercial sensors have been integrated into the wristwatch for transcutaneous gas sensing. In the second approach, CMOS camera-based colorimetric sensors are integrated into the wristwatch, where a part of camera frame is used for photoplethysmography while the remaining part tracks the optical signal from colorimetric sensors. Finally, the wireless connectivity using Bluetooth Low Energy (BLE) in wearable systems has been explored and a data transmission protocol between wearables and host for reliable transfer has been developed. To improve the transmission reliability, the host is designed to use queue-based re-request routine to notify the wearable device of the missing packets that should be re-transmitted. This approach avoids the issue of host dependent packet losses and ensures that all the necessary information is received. The works in this thesis have provided technical solutions to address challenges in wearable technologies, ranging from chemical sensing, flow sensing, data analysis, to wireless data transmission. These works have demonstrated transformation of traditional bench-top medical equipment into non-invasive, unobtrusive, ergonomic & stand-alone healthcare devices. / Dissertation/Thesis / Doctoral Dissertation Electrical Engineering 2020

京都大学 / 新制・課程博士 / 博士(理学) / 甲第22998号 / 理博第4675号 / 新制||理||1670(附属図書館) / 京都大学大学院理学研究科物理学・宇宙物理学専攻 / (主査)准教授 金田 佳子, 教授 萩野 浩一, 教授 田中 貴浩 / 学位規則第4条第1項該当 / Doctor of Science / Kyoto University / DFAM

This diploma thesis examines the economics of use of technologies linked with low-energy, passive, and active house construction which is presently very often a topic of interest. The goal of the thesis is to evaluate economic effectivity of additional investment into construction materials leading to reduction of heating requirements of the evaluated family house. Furthermore, economics of the use of advanced technologies of ventilation, different heat sources and photovoltaic power plant are assessed. The result is a complex evaluation of different alternatives of the house which makes this thesis helpful in answering the question whether these additional investments will pay off.

Diplomová práce se zabývá vytvořením modelu, který by umožnil lepší interpretaci hloubkových profilů měřených metodou LEIS. Obtížnost interpretace těchto profilů je dána vysokým podílem vícenásobně odražených projektilů v meřených spektrech. Tyto projektily nepřináší užitečnou informaci z dané hloubky. Naproti tomu jednonásobně odražené projektily nesou přesnější informaci o složení a tloušťce vrstev. V této práci vytvořený model se snaží určit příspěvek jednonásobně odražených částic k celkovému tvaru spektra a na základě něj i hloubkový profil vzorku.

The threshold potentials were determined for the excitation energy necessary for low energy electrons to induce chemical reactions of carbon monoxide, and of nitric oxide adsorbed on a gold surface. The reactions were studied as a function of temperature (100 °C to 200 °C) and pressure (1.83 x 10-5 to 6.40 x 10-4 torr). The electron source was a thorium oxide coated iridium filament which was heated by a current between 1A and 3A to keep thermal distribution of the electrons to less than 0.4 ev. The reaction surface was a polycrystalline evaporated film prepared by subliming gold onto a stainless steel mesh support. Mass analysis was done by quadrupole mass spectrometry in a flow system. The general results of the research is that a technique has been developed to study the products of reactions of excited state atoms or molecules on metal surfaces. The electron-impact excitation method is an alternative to photochemical and other methods.