Spelling suggestions: "subject:"thermoset monkey""
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Imaging brain activity in conscious monkeys following oral MDMA ("Ecstasy").Harder, Josie A., Brevard, M.E., Ferris, C.F., Meyer, J.S. January 2006 (has links)
No / Recreational use of 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy") poses worldwide potential health problems. Clinical studies show that repeated exposure to low oral doses of MDMA has toxic effects on the brain, altering cognitive and psychosocial behavior. Functional magnetic resonance imaging in conscious marmoset monkeys was used to evaluate the sensitivity of the brain to an oral dose of MDMA (1 mg/kg). Following MDMA administration, the midbrain raphe nuclei and substantia nigra, major sources of serotonin and dopamine, were activated as were the hippocampus, hypothalamus and amygdala. The corticostriatal circuit of dorsal thalamus, sensorimotor cortex and basal ganglia showed a robust, coherent activation pattern. Two key reward areas, the nucleus accumbens and prefrontal cortex, and most other cortical regions showed little activation. The visual cortex, however, showed intense activation without applied visual stimuli. These data identify brain areas and functional circuits sensitive to a recreational dose of MDMA, some of which may be vulnerable to long-term intermittent exposure to this drug.
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Embryonic and foetal germ cell development in the marmoset monkey: comparative in situ and cell culture studiesWolff, Eva 15 October 2018 (has links)
No description available.
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Feasibility of combined upper and lower gastrointestinal endoscopic biopsy in the common marmoset (Callithrix jacchus) to evaluate gastrointestinal diseasesHeilmann, Romy M., McIntosh, Jenny, Acke, Els, Reitemeier, Susanne, Pfannkuche, Helga, Erdmann, Sabrina, Roedler, Frauke S., Einspanier, Almuth 27 July 2023 (has links)
Background: Chronic gastroenteropathies, including gluten sensitivity and marmoset
wasting syndrome, frequently occur in captive colonies of common marmosets
(Callithrix jacchus). Early identification and diagnosis of affected animals are desirable.
Endoscopic examination of the colon in marmosets is described, but the small
intestine can harbor significant mucosal lesions not representing those in the colon.
Evaluating the small intestine currently requires invasive surgical biopsies due to the
small patient size, carrying a risk of severe complications.
Methods: Endoscopic intubation and multisite biopsy of the duodenum/proximal jejunum
are demonstrated in 10 marmosets under general anesthesia.
Results: Esophagogastroduodenoscopy with colonoscopy efficiently aid in examining
the gastrointestinal tract and obtaining an antemortem histologic diagnosis in marmosets
with chronic gastrointestinal signs.
Conclusions: This minimally invasive technique is feasible in marmosets. Future investigations
into the pathogenesis of chronic gastroenteropathies will benefit from these
data, leading to improved animal welfare and better individual and colony health
management.
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Feasibility of combined upper and lower gastrointestinal endoscopic biopsy in the common marmoset (Callithrix jacchus) to evaluate gastrointestinal diseasesHeilmann, Romy M., McIntosh, Jenny, Acke, Els, Reitemeier, Susanne, Pfannkuche, Helga Pfannkuche, Erdmann, Sabrina, Roedler, Frauke S., Einspanier, Almuth 28 August 2023 (has links)
Background: Chronic gastroenteropathies, including gluten sensitivity and marmoset
wasting syndrome, frequently occur in captive colonies of common marmosets
(Callithrix jacchus). Early identification and diagnosis of affected animals are desirable.
Endoscopic examination of the colon in marmosets is described, but the small
intestine can harbor significant mucosal lesions not representing those in the colon.
Evaluating the small intestine currently requires invasive surgical biopsies due to the
small patient size, carrying a risk of severe complications.
Methods: Endoscopic intubation and multisite biopsy of the duodenum/proximal jejunum
are demonstrated in 10 marmosets under general anesthesia.
Results: Esophagogastroduodenoscopy with colonoscopy efficiently aid in examining
the gastrointestinal tract and obtaining an antemortem histologic diagnosis in marmosets
with chronic gastrointestinal signs.
Conclusions: This minimally invasive technique is feasible in marmosets. Future investigations
into the pathogenesis of chronic gastroenteropathies will benefit from these
data, leading to improved animal welfare and better individual and colony health
management
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Non-human primate iPS cells for cell replacement therapies and human cardiovascular disease modelingRodriguez Polo, Ignacio 29 October 2019 (has links)
No description available.
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