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According to the biopsychosocial model of bulimia, neurobiological mechanisms called endophenotypes cause eating disordered behavior. Impulsivity has been identified as a possible endophenotype for bulimia nervosa, and individuals with bulimia who present with multiple forms of impulsive behavior are known to have worse prognoses. Executive dysfunction in impulse control purportedly manifests as behavioral under-regulation in binge-purge episodes. Neuropsychological assessments were used to analyze the relationship between impulsivity and symptoms of bulimia. Twenty-eight inpatient adolescent and young adult women with bulimia completed the D-KEFS Color Word Task, which is a version of the Stroop that contains four trials including the classic Stroop and a switching Stroop, as well as the age appropriate versions of the BRIEF rating scale and a Type-T Survey of thrill-seeking. Performance on these measures was correlated with measures of bulimia symptoms, including the EDI-3, EDE-Q, and variables of illness severity. Delay of gratification was assessed by offering subjects a choice of compensation that was either immediate and smaller or delayed and larger. Mixed results were found. The sample did not differ from the D-KEFS normative sample on total number of errors or on speed of task completion for the switching Stroop, and the sample demonstrated faster performance than the normative sample on the classic Stroop. However, a tendency to favor speed over accuracy of performance was identified. On the BRIEF rating scales, the sample self-reported significantly higher rates of executive dysfunction compared to the normative data. Additionally, some variables of impulsivity, including greater frequency of errors on cognitive tasks and self-reported deficits of executive functioning, were significantly correlated with variables of bulimia symptom severity, including self-reported bulimia symptomatology on the EDI-3 and frequency of bingeing and purgeing. Risk-taking was also found to be correlated with symptoms of bulimia. Differences were found between subjects who chose the immediate prize versus those who chose the delayed prize, including differences in cognitive task performance and symptom severity. Differences were also found for subjects with a comorbid disorder of impulse control, including bipolar disorders and substance abuse. In conclusion, a unilateral deficit of impulse control was not found to be characteristic of this sample; however, a multi-impulsive cohort was identified as having deficits of cognitive impulse control. / School Psychology

Yes / We report that performance on neuropsychological tests used in the diagnosis of dementia can be influenced by external factors such as time of day (TOD) and caffeine. This study investigates TOD effects on cognitive performance in the elderly. The optimal TOD at which an individual is at their maximal arousal alters with age and in the elderly typically occurs in the morning. Neuropsychological test scores from healthy elderly participants were analysed to determine whether TOD affected performance. Interactions between caffeine and TOD were also investigated. Across two data sets that were analysed, significant TOD effects were noted for Pattern Comparison Speed (PCS), Letter Comparison Speed (LCS), Trail Making Test Part A, Mini Mental State Examination (MMSE) and the Graded Naming Test (GNT), revealing a decline in test scores as TOD increases. Significant interactions between TOD, age and the PCS, LCS and Trail Making part A were noted in data set one. In data set two, where caffeine intake had been controlled for, significant interactions between caffeine, TOD and scores on the MMSE and GNT were found. The TOD and caffeine effects highlight the need to control for these external factors when scoring the assessments. This conclusion has implications for the clinical procedure of diagnosis and treatment of dementia and Alzheimer’s.

The present study investigated the neuropsychological predictors of auditory/verbal and visual/written arithmetic performance in a large sample of children with learning disorders. In addition, the efficacy of a cognitive based arithmetic problem solving model (Dinnel, Glover, & Halpain, in press; Dinnel, Glover, & Ronning, 1984) in accounting for neuropsychological functioning in arithmetic performance was considered. Subjects were from a small midwestern school district, and were identified as learning disabled in accord with state (i.e., Rule S-1) and federal guidelines (i.e., PL-94-142). Specifically, subjects' scores on the Halstead-Reitan Neuropsychological Battery (HRNB) (Reitan, 1969) for older children and the Wechsler Intelligence Scale for Children-Revised (WISC-R) (Wechsler, 1974) were used to predict performance on the Wide Range Achievement Test (WRAT) Arithmetic subtest, and WISC-R Arithmetic subtest. Analyses were conducted with criterion measures considered separately and as a composite. In an attempt to examine the utility of the Dinnel et al., (in press; 1984) model, a simple index was formed using the criterion measures. This index was then predicted using the HRNB and WISC-R variables. Neuropsychological variables were found to account for some 31%, and 36% of the variability in visual/written and auditory/verbal arithmetic performance, respectively. However, neuropsychological variables accounted for some 87% of the shared variance when arithmetic measures were considered as a linear composite. Neuropsychological variables predicted a mere 12% of the variability associated with the index designed to test the Dinnel et al. (in press; 1984) arithmetic problem solving model. These data offered some support to Dinnel and others' (Dinnel et al., in press; 1984) formulations accounting for arithmetic performance under visual/stimulus conditions. However, the present findings indicated a more complex neuropsychological underpinning for overall arithmetic problem solving. Moreover, the neuropsychological constructs predicting arithmetic scores varied as a function of the stimulus/performance modes required for problem solving.Auditory-verbal attention and short-term memory, remote verbal memory, symbolic language integration, mental flexibility, and nonverbal abstract reasoning were the common neuropsychological constructs underpinning both auditory/verbal and visual/written arithmetic performance. Verbal facility, verbal abstract reasoning, nonverbal short term memory, and nonverbal concrete concept formation were uniquely implicated in auditory/verbal arithmetic performance. Visual/written arithmetic performance was uniquely related to nonverbal attention and intermediate nonverbal memory functions. In overview, it would seem that neuropsychological measures would be clinically useful in identifying deficits underlying poor arithmetic performance. / Department of Educational Psychology

Thesis (Ph. D.)--Illinois State University, 2001. / Title from title page screen, viewed March 14, 2006. Dissertation Committee: Mark E. Swerdlik (chair), David L. Wodrich (co-chair), Valeri Farmer-Dougan, Alvin House. Includes bibliographical references (leaves [106]-117) and abstract. Also available in print.

Thesis (M.Soc.Sc. Psychology)--University of Waikato, 2006. / Includes bibliographical references (leaves 58-69)

This dissertation focuses on available means of the assessment of cognitive functions in neurological patients in the Czech environment. The main goal was to verify the psychometric qualities and usability of the Czech version of the Neuropsychological Assessment Battery (NAB). NAB is a test battery that assesses attention, language, memory, and spatial and executive functions. The theoretical part of the dissertation introduces the basic cognitive functions and diagnostic tools for their assessment; the next chapter focuses on NAB and especially its psychometric characteristics. Third chapter describes specific diseases (epilepsy and psychogenic seizures), their manifestations and impact on cognition. Empirical part included participation in the adaptation of NAB to the Czech language. During the research, a group of healthy volunteers (n = 116) and patients from the Epilepsy Monitoring Unit (n = 60) were tested by the NAB Screening Module. To verify the convergent validity of NAB-SM we administered Repeatable Battery for the Assessment of Neuropsychological Status (including an Effort Index) to a part of the sample. Based on the results, we can conclude that NAB-SM appears to be a suitable method for the assessment of cognitive functions in patients with psychogenic non-epileptic seizures. The...

The research entails the early identification of neuropsychological learning disabilities in grade 1 learners. The researcher used the definition, criteria and characteristics of the DSM-IV for the identification of neuropsychological learning disabilities. The section of Learning Disabilities or Disorders includes Reading Disorders, Mathematic Disorder, Disorder of Written Expression and Learning Disorder Not Otherwise Specified. Learning Disabilities are diagnosed when the learner’s achievement on individually administrated, standardized tests in reading, mathematics or written expression is substantially below that expected for age, schooling and the level of intelligence. The learning problems, such as unsatisfied reading, mathematical or writing skills, significantly interfere with the learner’s academic achievement. Mathematic Disorder and Disorder of Written Expression most commonly occur as early as in the beginning or first grade, when formal reading instruction usually begin. Neuropsychological learning disabilities have a negative influence on the learner’s scholastic achievement, social development and emotional functioning. The research is focused on the grade 1 learners only. There is no differentiation regarding gender. In the literature study, the researcher observed five important components regarding neuropsychological learning disabilities, namely:- -- Definition, criteria and characteristics; -- Classification; -- Causes; -- The localization of the cortical areas of the brain associated with neuropsychological abilities; and -- The Neurofeedback. The Neurofeedback is based on the tenents that brain electrical activity reflects mental status and that the activity can be trained. The researcher also observed in the literature study certain risk factors regarding neuropsyhological learning disabilities, namely phonological awareness, analysis, synthesis, word recognition and syntax. The researcher considered these components in conjunction with the compilation of the neuropsychological test battery. The researcher could determine the follow findings with the assistance of the neuropsychological test battery:- -- The developmental delays which are present. -- The brain areas in which the cognitive abilities, associated with the developmental delays, are located. -- The limited functioning of brain wave activities which are associated with the cognitive abilities and developmental delays. -- The early idenitification of neuropsychological learning disabilities in grade 1 learners. The researcher found that the Neurofeedback programme is a useful contribution for the early identification of neuropsychological learning disabilities in grade 1 learners. / Thesis (PhD (Learning Support, Guidance and Counselling))--University of Pretoria, 2006. / Educational Psychology / unrestricted