Global ETD Search

41	Experience of adjuvant treatment among postmenopausal women with breast cancer : health - related quality of life, symptom experience, stressful events and coping strategies / Browall, Maria, January 2008 (has links) Diss. (sammanfattning) Göteborg : Göteborgs universitet, 2008. / Härtill 4 uppsatser.
42	Genetic determinants of postmenopausal breast and endometrial cancer / Kristjana Einarsdóttir, January 2007 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 4 uppsatser.
43	Genetic susceptibility to breast and endometrial cancer / Wedrén, Sara, January 2004 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2004. / Härtill 5 uppsatser.
44	The effect of sex hormones on hemostasis and cardiovascular riskfactors in postmenopausal women / Pripp, Ulla, January 2004 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2004. / Härtill 5 uppsatser.
45	Testosterone treatment in women : aspects on sexuality, well-being and metabolism / Flöter Rådestad, Angelique, January 2004 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2004. / Härtill 5 uppsatser.
46	Acupuncture : the effects on muscle blood flow and aspects of treatment in the clinical context / Sandberg, Margareta, January 2004 (has links) (PDF) Diss. (sammanfattning) Linköping : Linköpings universitet, 2004. / Härtill 6 uppsatser.
47	Mammographic breast density and postmenopausal hormone therapy / Lundström, Eva, January 2005 (has links) Diss. (sammanfattning) Stockholm : Karol. inst., 2005. / Härtill 5 uppsatser.
48	Effects of testosterone treatment on metabolism and endometrium in postmenopausal women / Zang, Hong, January 2007 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 4 uppsatser.
49	Hormone-related dietary factors and estrogen/progesterone-receptor defined postmenopausal breast cancer / Suzuki, Reiko, January 2006 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2006. / Härtill 4 uppsatser.
50	Estudo da via Wnt no endométrio normal e no câncer de endométrio, em mulheres após a menopausa / The role of Wnt pathway in the normal endometrium and in the endometrial cancer the post menopause women Menezes, Marina de Pádua Nogueira [UNIFESP] 29 June 2011 (has links) (PDF) Made available in DSpace on 2015-07-22T20:50:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-06-29. Added 1 bitstream(s) on 2015-08-11T03:26:07Z : No. of bitstreams: 1 Publico-12659.pdf: 1883382 bytes, checksum: 33bb0f719078a000b15563f9e2debf90 (MD5) / A familia de genes Wnt esta envolvida na carcinogenese de diversos tecidos e na embriogenese. Para avaliar as vias Wnt canonica e nao-canonica no endometrio atrofico e no cancer de endometrio, avaliamos a expressao imuno-histoquimica do Wnt1, Frizzled-1 (FZD1), Wnt5a, Frizzled-5 (FZD5) e ƒÀ-catenina. O tecido endometrial foi retirado de pecas cirurgicas de pacientes operadas entre 1995 e 2005 na Escola Paulista de Medicina . UNIFESP e foram divididas em dois grupos: grupo A, endometrio atrofico (n=15) e grupo B, adenocarcinoma de endometrio (n=45). A imunorreacao do Wnt1, FZD1, Wnt5a, FZD5 and ƒÀ-catenina foi analisada em escores em cada grupo, individualmente. A expressao do Wnt1, FZD1 e Wnt5a nao teve associacao significante entre os grupos. Associacao significante foi observada entre os grupos para a expressao do FZD5 (p = 0,001). A proporcao do FZD5 positivo foi significativamente maior no grupo A (80,0%) comparado ao grupo B (31,1%). Analisando a curva de sobrevida para o FZD5 no grupo B, nao encontramos associacao significante entre as mulheres positivas e negativas. A expressao da scatenina nao foi significante, sendo a expressao para os grupos A e B 100% e 95.6%, respectivamente (p = 1,000). FZD5 tem menor expressao no adenocarcinoma de endometrio tipo I quando comparado ao endometrio atrofico. / The Wnt family is involved in tumorigenesis of several tissues as well in embriogenesis. In order to analize the canonical and noncanonical Wnt pathway in atrophic endometrium and endometrial adenocarcinoma, we evaluated the immunohistochemical expression of Wnt1, Frizzled-1 (FZD1), Wnt5a, Frizzled-5 (FZD5) and ƒÀ-catenin. Endometrial specimens were obtained from surgeries performed between 1995 and 2005 and the patients were divided in two groups: Group A, atrophic endometrium (N = 15); Group B, endometrial adenocarcinoma (N = 45). Immunoreactivity for Wnt1, FZD1, Wnt5a, FZD5 and ƒÀ-catenin was scored for each group. For the expression of Wnt1, FZD1 and Wnt5a, no significant association was observed between the groups. A significant association was observed between the groups for the FZD5 expression (p = 0.001). The proportion of FZD5 positive women was significantly higher for group A (80.0%) compared to group B (31.1%). Regarding the survival curve for FZD5 at group B, we found no significant association between positive and negative women. No significant association was observed between s-catenin expression and the patient group since the expression for groups A and B were 100% and 95.6%, respectively (p = 1.000). FZD5 is downregulated in type I endometrial adenocarcinoma when compared to atrophic endometrium. / TEDE / BV UNIFESP: Teses e dissertações Endométrio Mulheres Proteinas Wnt Pós-menopausa Neoplasias do endométrio Endometrium Postmenopause Wnt Proteins Women Endometrial neoplasms

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