This thesis deals with the examination of damper characteristics and influence of individual parameters on vehicle handling, primarily with the use of computer program Matlab Simulink.

In her diploma thesis, the author deals with the Quarter-life crisis and the experience that Czech Millenials have with this phenomenon. Given that Quarter-life crisis is a relatively new concept that has not yet been greatly explored by academics, the author devotes a part of the thesis to a detailed account of the knowledge on this phenomenon that is currently available, with a considerable part coming from popular psychology and popular science books. The theoretical part of the thesis further describes the social change that enabled the emergence of a new period in psychological development - the "emerging adulthood" and the associated Quarter-life crisis, its development as a concept and academic recognition. The work further describes the generation of Millenialls currently associated with this crisis and their characteristics making them susceptible to experience this crisis. The practical part is a qualitative research on the experiences of Czech Millenials, who are going through or have gone through this crisis. The research results are analysed with an consideration of the specifics of the Czech environment and unique factors that can influence the experience with this phenomenon.

The goal of this diploma thesis is to evaluate the actual performance and actual status of American western breeds in Czech Republic. The statistical analysis is based on data from the Central register of horses, breeders associations and on the results of one of the accredited discipline by ČJF and FEI, reining. The results were collected between the years 2013 and 2015 from ČJFs archive. The analysis uses the GLM, dependent variables were points earned in the competition and placement in the competition, the effects were breed of the horse, age of the horse, year of the competition, level of the competition, the rider and the equestrian association. Also in the case of signification effect was Scheffes and Tukey-B multiple comparison test used. Through the analysis of data mentioned above it was found that the amount of bred western horses in Czech Republic has an increased trend, also their efficiency in reining competitions improves. The most popular breed of western horses bred in Czech Republic is American Quarter horse which is also in reining represented most often, followed by American Paint horse and Appaloosa.

Linear weirs are a common hydraulic structure that have been used for centuries with many different applications. One characteristic of weirs that is particularly useful is the head-discharge relationship where the discharge over the weir is directly related to the upstream water depth above the crest. In general, the head-discharge relationship for a weir is determined experimentally in laboratories using geometrically similar models. Due to space, time, money, and discharge capacity limitations at water laboratories, creating full scale models is not always a feasible option when determining head-discharge relationships for large prototype weirs. It is typically more cost effective to create a scale model than to build a full scale model or conduct tests on the prototype. Because of this fact, physical modeling has been one the most important tools in determining head-discharge relationships for weirs. However, as the physical size of the model decreases, size scale effects associated with surface tension and viscosity forces can significantly affect the results from the physical model and cause the results to differ from what would actually occur at the prototype scale. Therefore, it is important to understand what affects surface tension and viscosity forces have on the head-discharge relationship for different size weirs and when those effects are no longer negligible. The purpose of this research was to evaluate size scale effects for linear weirs. Weirs models of three different crest shapes (flat-top, quarter-round, and half-round) were constructed and tested at four different geometrically similar sizes [weir heights (P) = 24-, 12-, 6-, and 3-in]. This was done in order to evaluate how size scale effects affect the head-discharge relationship as model size decreases for different crest shapes. Discharge coefficients were calculated for relative upstream head values ranging from 0.01 ≤ Ht/P ≤ 2.0 for vented and non-vented conditions. Nappe aeration behavior was documented and compared to determine where differences in the nappe trajectory occurred as a result of scale effects. Comparisons were made with data from others researchers to determine if the recommendations for minimum head limits were similar to the results from this study. This study examined the errors in the discharge coefficient associated with size scale effects and suggested limits to avoidance depending on model scale and crest shape.

No description available.

Hereditary Equine Regional Derma Asthenia (HERDA) is a painful disfiguring autosomal recessive skin disorder of Quarter Horse lineages. Affected horses cannot be ridden and most are humanely destroyed. Five years following homozygosity mapping of a putative causal mutation responsible for HERDA, it remains unclear how this mutation causes the HERDA syndrome. HERDA horses have a missense mutation in peptidyl-prolyl cis-trans isomerase B (PPIB) which encodes cyclophilin B (CYPB) and alters folding and post-translational modifications of fibrillar collagen. Loss of function mutations in CYPB recognized in other species classically present as the debilitating bone disease, severe to lethal osteogenesis imperfect (OI). Objectives of this study were to develop a novel method for cryogenic clamping of tendons and ligaments of high tensile strength and validate its performance by ultimate tensile strength testing of normal equine deep digital flexor tendon. This validated method was then used to compare tendon and ligament of HERDA vs. control horses along with great vessels and skin. We hypothesized that all tissues of high fibrillar collagen content would have altered tensile properties due to the CYPB mutation affecting fibrous connective tissue globally within HERDA horses. Based on previous studies in our laboratory identifying reduced hydroxylysine content and altered collagen crosslink ratios in the skin of HERDA affected animals that implicate lysyl hydroxylase-1 (LH1) dysfunction, we hypothesized that the HERDA PPIB mutation modified an interaction between CYPB and LH1, interfering with hydroxylysine synthesis and its availability for collagen crosslink formation. In addition, we hypothesized that mutant CYPB may also lead to modifications of other known CYPB protein complexes, such as the CYPB, prolyl-3 hydroxylase-1 (P3H1) and cartilage associated protein (CRTAP) triplex. Goals of this study were to investigate the tensile properties of tissues with high fibrillar collagen content from HERDA homozygotes, to elucidate the mechanistic relationship of the HERDA CYPB mutation to the clinical disease, and to provide evidence to substantiate a heterozygote phenotype in HERDA which could be useful to explaining the correlation between lineages that carry the HERDA allele and performance outcomes in the discipline of western cutting competition.

The project seeks to return the importance Koláčkova square within the town. Modifying a own recovery gives the required city-forming element. Also, the function of the new buildings will increase usage of center. Information center, library, reading room, cafe and rooms for rent and housing for people over 50 years of creating polyfunctional buildings. Suitably elected ratio of built and unbuilt space adds the square of appropriate scale.

The main subject matter of this thesis is to design a renewal strategy and revitalization of the Jewish quarter in Třebíč. Even though it has recently been filed on a prestigeous list of UNESCO heritage sites and the town has seen significant effort in the direction of its renewal, this quarter still has some drawbacks. One of the problems observed is the inadequate technical condition of considerable number of buildings, while other is the insufficient usage of public areas. One can still notice the stigma of a socially excluded and a dangerous district. These traits are most evident in the immediate vicinity of the Subak’s factory. Main goal of this work is to coin an identity change of this site and transform it into an attractive and safe place, unique for its history and atmosphere – a quarter suitable for long-term residence as well as short-term visit. In achieving these goals, methods of tactical urbanism have been employed in the form of public space intervention and then a long-term visions are proposed in the form of the design of new functions at the site and a reconstruction of the formerly torn down historical buildings. A very important aspect of the proposed solution is the preservation of the historical urbanistic structure of the quarter and a respect for contemporary requirements laid on modern functions of a residential area at the same time.

PURPOSE/BACKGROUND: Muscle fatigue is related to a decline in force output and proprioception. These can ultimately have an adverse effect on neuromuscular control and functional performance. Local muscle fatigue has been shown to have adverse consequences on dynamic standing balance; however, much less is known regarding the relationship between distant fatigue and dynamic standing. The purpose of this study was to investigate the effects of upper body fatigue on dynamic standing balance. It was hypothesized that distant fatigue in upper body musculature would show a significant decrease in dynamic standing balance as assessed by the Lower Quarter Y-Balance Test (YBT-LQ). METHODS: TWENTY HEALTHY INDIVIDUALS (AGE: 25.0 ± 3.42 years, height: 172.72 ± 13.11 cm, mass: 71.36 ± 13.50 kg) participated in this study. A kayak ergometer was used to implement a fatigue protocol for the upper body. The protocol consisted of a graded intensity session ranging from 50% to 90% of maximum effort lasting ten minutes in duration (2 minutes each at 50% 60%, 70%, 80%, and 90%). The anterior (ANT), posteromedial (PM), and posterolateral (PL) reach directions were normalized to leg length and measured on the YBT-LQ before and after the fatigue protocol for each participant. A fourth value termed overall balance was calculated as the sum of the furthest reach distance of the three directions. Blood lactate analysis taken before and immediately after the fatigue protocol was used to quantify fatigue. Multiple paired t-tests were performed for pre-fatigue and post-fatigue balance assessment. A Bonferroni correction was applied to set the significance value ≤0.0125 a priori. Effect size was calculated using the effect size index. RESULTS: Blood lactate values immediately following the fatigue protocol had an average concentration of 6.15 millimoles (pre: 2.3, post: 8.4). The ANT reach direction (ρ = 0.004) and the calculated overall balance (ρ = 0.011) significantly decreased post-fatigue in the dominant lower extremity. No significant differences were found for the PM (ρ = 0.017) or PL (ρ = 0.021) directions. The ANT reach direction (0.64) and overall balance (0.44) also showed a moderate effect size based on the effect size index. CONCLUSIONS: ANT and overall dynamic standing balance were negatively affected after completing the upper body fatigue protocol. The findings of this research demonstrate that upper body fatigue has adverse effects on dynamic standing balance, as measured by performance on the YBT-LQ. Significant and clinically relevant differences were noted in ANT and overall dynamic standing balance. CLINICAL RELEVANCE: Physical therapists should be aware of the adverse influence distant fatigue may exhibit on neuromuscular control in muscles not actively involved in the fatiguing exercise. The balance deficits noted may indicate an increased risk of injury with muscle fatigue in muscles not directly contributing to standing balance. LEVEL OF EVIDENCE: 3b, Case-control study.

This study explores the linguistic characteristics of the Arabic dialect spoken in Ḥayy ə-s-səryān, also known as the ‘Syriac Quarter’ in Aleppo city, within the context of the city's diverse demographic makeup. The Aleppo dialect, a Levantine dialect spoken by various religious and social groups, is used by Christians and Muslims as their everyday language. The Jewish population, historically present in Syria, gradually left the city in the twentieth century. The Aleppo dialect among Christians and Muslims is classified into different types, considering factors like origin and migration. Previous studies by Sabouni and Behnstedt have examined the Muslim and Christian varieties, respectively, but Sabouni did not consider the Christian variety of the dialect and Behnstedt had limited focus on the Syriac Quarter dialect. This research aims to address this gap by analyzing and comparing various dialectal varieties in Aleppo, with a particular emphasis on the Syriac Quarter variety. In addition, the thesis examines the substratum of Aramaic in the dialect of Aleppo. The methodology involves the researcher's recordings of individuals from Aleppo's original Christian and Syriac Quarters. Transcriptions from scholars like Sabouni and Behnstedt were also utilized, with modifications for consistency. The researcher, a native speaker of the Aleppo dialect born in the Syriac Quarter, conducted interviews with individuals from both communities. Christians and Muslims in old town Aleppo initially shared linguistic similarities, residing in common quarters like al-Jallum. Over time, Christians moved to new areas, leading to separate residential zones. An Aramean group migrated from present-day Urfa (historical Edessa/Urhoy) in the early 20th century. The Edessan Syriacs arrived in Aleppo in 1924 and settled in the district that later became known as the Syriac Quarter, experiencing a multilingual environment. They adopted colloquial Arabic influenced by Syriac, Armenian and Turkish.  This research discusses the evolving linguistic landscape in Aleppo due to migrations and cultural interactions. The study explores linguistic variations in the Aleppo dialect, shedding light on the influences shaping its diverse forms.