This thesis is about an inovative program in teaching English language called EATS. The goal was to find out the effectivness of this program on the basis of repeated observations, didactic testing and interview. In the theoretical part the position of English language in the curricular documents is discussed. Then there is the description of the communicative approach to the language learning which is very useful in nowadays globalised society.The important role of the native speaker is emphasized because he brings the authentic element into the education process and gives pupils good language model. Also the early education in foreign languages is part of this work. Integrated language learning is described on the ilustration of CLIL and its alternative which could be called "language preparation". The aim was to show an example of a good practice which could inspire someone.

Cardiovascular pharmaceuticals are among the most prescribed drugs. As a result of the high consumption, these pharmaceuticals have been frequently detected in waste and surface waters. Verapamil, diltiazem and atenolol are very important representatives of cardiovascular pharmaceuticals; therefore, the present research focused on their acute and sub-chronic effects, bioconcentration, half-life time and metabolism in fish. Moreover, unified protocol for the quantitative assessment of histopathological alterations on the heart ventricle and coronary blood vessels employing heart index calculation was developed with the aim to better assess histopathological changes in fish heart which is one of the targets of cardiovascular pharmaceuticals and other chemicals. The effects caused by high concentrations of the studied substances, verapamil, diltiazem and atenolol, in fish can be considered similar to the therapeutic effects and side effects that are found in humans. The acute exposure to verapamil at the human therapeutic plasma level reduced the heart rate in common carp embryos and larvae. In addition, the acute and chronic exposure to this substance caused peripheral edema and gastrointestinal haemorrhage in carp. Similarly, the histological changes in heart and the blood vessels of the liver in diltiazem exposed rainbow trout suggested vasodilatation similar to the pharmacological effect of diltiazem in the human body. In rainbow trout sub-chronically exposed to atenolol at a human therapeutic blood plasma concentration, histopathological changes in the cardiovascular system were found. The bioconcentration of verapamil, diltiazem and atenolol in fish can be classified as low. Bioconcentration factor (BCF) of verapamil in whole body homogenates of common carp ranged between 6.6 and 16.6. The BCF of diltiazem was also relatively low (0.5-194) in analysed tissues of trout, following the order kidney liver muscle blood plasma. BCF of atenolol in rainbow trout tissues was the lowest among the tested substances (BCF = 0.002-0.27), following the order of liver > kidney > muscle. In the blood plasma, the concentration of atenolol was below the limit of quantification. Verapamil showed a longer half-life time (10.6 days) in fish compared to the human body, indicating the slow rate of biotransformation and/or elimination of verapamil in fish. Estimated half-life times of diltiazem in liver (1.5 h) and kidney (6.2 h) were in the same order of magnitudes as those determined for the human blood plasma. The half-life time of atenolol in trout was not studied, because of its very low bioconcentration. In diltiazem exposed rainbow trout, 8 groups of metabolites of diltiazem with 17 different isoforms were identified using liquid chromatography/high resolution mass spectrometry method. Diltiazem was found to undergo a biotransformation involving desmethylation, desacethylation and hydroxylation in fish. These results showed that diltiazem was metabolised in fish in a similar way like in the human body by desmethylation and desacethylation. On the other hand, hydroxylation, which was involved to a minor extent, seemed to be species specific. Verapamil had no effect on early life stages of common carp at the environmentally relevant concentration after one month lasting exposure. On the other hand, atenolol and diltiazem in environmentally realistic concentrations caused after 42-day exposure some physiological changes in rainbow trout. Namely, atenolol affected haematological and biochemical parameters of the blood in exposed rainbow trout and diltiazem caused changes in the activity of antioxidant enzymes in trout liver and gills. These data indicated that atenolol and diltiazem, when present in the aquatic environment, could be a source of sub-lethal detrimental effects in fish.

The scope of this dissertation focuses on issues related to the quality of life of children suffering with spinal muscular atrophy (SMA) and their carers and the associated social impact on families affected by this progressive and incurable disease. It describes ethical aspects of help to families with SMA and serious decisions in relation to the need to connect to artificial ventilation. Spinal Muscular Atrophy - SMA is a motoneuron disease i.e. disease of neurons, which are responsible for conscious movements of muscles e.g. running, head movement and swallowing. The prevalence is approximately 1 newborn for 6000 live births and approximately 1 person of 40 people is the carrier of the disease. SMA affects all the bone muscles i.e. proximal muscles are often affected the most. Everyone affected is in some point in life, depending on stage and type, reliant on mechanical or electrical wheelchair, in many cases also on artificial ventilation and permanent 24hr care. Families affected by this illness accept the fact of this progressive and incurable illness differently, this dissertation reflects upon such different perceptions on quality of life of the affected children, the carers. It forms a contribution in building a foundation for organising multi-discipline teams of experts with sole purpose of therapeutical interventions, to support the child and his/hers family. The World Health Organization (WHO) defines palliative care as "improving quality of life of patients facing life-threatening illnesses, and their families, through the prevention and relief of suffering by early identification and treatment of pain and other problems, whether physical, psychological, social or spiritual." Palliative care prepares families for these situations and should be provided along with whatever treatment options families choose. This dissertation is a comprehensive information base to support children affected by SMA and their families in early care in Czech Republic and in the process of inclusive educational integration into mainstream society.

The thesis deals with a topical and at the same time controversial isssue in the pre- shool education - the very early foreign language learning. The aim of the thesis is to outline the conditions of English language learning in pre-school facilities in the Czech Republic (more precisely in Prague) and analyse and compare selected methods used for teaching English. The thesis consists of the theoretical and the practical part. The theoretical part focuses on early language learning in the Czech and European context, on curriculum conditions and teachers' qualification in the Czech Republic and on the individual particularities of a pre-school child in relation to the early language acquisition. The summary will offer various opinions and results of researches in the field of early foreing language learning in the pre-school age. The aim of the practical part is to compare two methods for teaching English and survey the present conditions of English learning in selected pre-school facilities in Prague. The research will focus on the methods and their evaluation, on the pre-school facilities' experience with teaching English and on the contributions and disputable questions rising from the early English language learning from the point of view of the directors, parents and and speacialist in the...

Master thesis titled Parents' reaction to a birth of a child with a disability deals with the process of coping with a birth of a disabled child and strategies that can help the family. In the first chapter, the function of a family and roles of parents in comparison with families with disabled children were defined. Reactions of parents when a disabled child is born in comparison with reactions of other social groups is discussed in second chapter. Third chapter focuses on factors which can help the parents to cope with the aforementioned situation. The last fourth chapter then depicts five families that shared their individual stories. The thesis also describes specific phases of dealing with difficult life situations including children born with disabilities. The thesis aims to analyse how parents reacted to birth of disabled child and which factors helped them to accept this reality. A research method in the form of an interview has been used. A confirmation of the hypothesis and thus achieving the thesis goal has been achieved be means of evaluation of answers from five respondents. The results have shown that such a childbirth is an unexpected situation for the parents, followed by a shock. The parents also have negative experience with doctors when delivering the diagnosis. Specific...

This case study based on a fieldwork carried out in a Day-Care Center tries to describe the process of the transition from mothering to wider society which is represented by a classroom of preschool children. Within this process we can note and describe specific ways of parent's, teacher's and especially children's actions. These activities are repeatedly produced. The point of departure is the Hirschfeld's article "Why Don't Anthropologists like Children?" (Hirschfeld, 2002) and his affirmation that children are active participants within process of accepting of social regulations and values and that they create their own culture, "children culture". This study ilustrates that the process of the transition from mothering to wider society is in the first place the process of the separation of child and mother. Within this process we note the function of the "object transitional" that compensate the absence of mother. And we can also observe how the group of pupils is formed and how their group identity is created. This group is situated in a specific place and time. And we observe that all individual actions concerning child are "embodied"- it's because we talk about an "experience that involve the whole person, including the body" (Abu-Lughold, Lutz, 1990 cit. in Ben-Ari, 1998: 138).

The aim of this research is to explore the influence of magnetic field on early somatic embryos (ESEs) of spruce and pine. The magnetic field is gradual. This is important for the experiment, each cluster of ESE was exposed to magnetic field of different intensity. The resulting report of this experiment consists of the comparison between various methods of image analysis and the difference in growth of ESEs due to different exposure to magnetic field and surrounding temperature. Enclosed is a proposal of ESE size computing algorithm from a given image.

The thesis is focused on the current possibilities of day care for children under three years and a deeper analysis of educational programmes supporting the development of children aged between two and three years in the capital city of Prague. The theoretical part summarizes the child care options in this age group, in terms of past and current offers in the Czech Republic, and covers the system of early intervention in selected European countries. With regard to the research objective, the work focuses on the child's needs, specific developmental areas and related educational programs that promote the development of the child's personality. For research, qualitative and quantitative methods are used - the methods of observation and questionnaires. The research is an analysis of the availability of interactive programmes for children, but also the potential of teachers to participate in the preparation, implementation and content of the programmes with regard to their experience and knowledge gained in working with young children. The research shows quite a wide selection of Czech and foreign programmes that aim to provide incentives for children to develop their abilities, skills and interests and enable the first steps toward socialization and adaptation to the new environment. The content of...

Introduction: The arrival of a child with multiple disabilities (MD) in a family is a difficult situation. Increased stress of parents of (MD) is often related to the non-fulfillment of the needs, leads to frustration and deprivation that can result in serious health problems. The aim is the subjectively defined and described life with a child (MD), focusing on the needs of these parents resulting from the daily care of the child. Aim: Identify, describe and analyze the needs of parents of children with MD at an early age. Methods: Qualitative approach using the biographical narrative method. The research design is a case study. Methodological triangulation: three methods of collecting data: biographical curve, in-depth interview, Cantril's ladder. Results: all cases were compared with each other. 12 parents' needs were identified. The Cantril's ladder method found significantly unmet needs: Need for rest and Need for medical care. Conclusion: The main contribution of the work is to understand the individuality and needs of parents of children with multiple disabilities, as a possibility to provide purposefully individualized early intervention, to streamline the process of planning, implementation and evaluation of provided care and thus contribute to the quality of life of the whole family.

The diploma thesis is focused on the support of early intervention in the inclusion of a visually impaired child into kindergarten. The work describes the development of a child with visual impairment at an early age. It also focuses on early care providing support to families with children with visual or combined disabilities, pre-school education and the support from a special education center. The aim of the work was to find out what is important for the parents of a visually impaired child when choosing a kindergarten, whether the inclusion is in accordance with the legislation and whether a multidisciplinary team participates in the support. As part of the research survey, qualitative research, aimed at monitoring family support for the inclusion of a visually impaired child in kindergarten by early care, was carried out. The results show that for families when choosing a kindergarten, it is most important to obtain information about the possibilities of including a child. Early intervention provides families with important information not only about the possibilities of inclusion, but also about the use of counseling services of a special pedagogical center. The choice of kindergarten is up to the parents, who take into account different aspects when choosing. An important indicator is the...