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Scientific knowledge is constructed and communicated through a range of forms in addition to verbal language. Maps, graphs, charts, diagrams, formulae, models, and drawings are just some of the ways in which science concepts can be represented. Representational competence—an aspect of visual literacy that focuses on the ability to interpret, transform, and produce visual representations—is a key component of science literacy and an essential part of science reading and writing. To date, however, most research has examined learning from representations rather than learning with representations. This dissertation consisted of three distinct projects that were related by a common focus on learning from visual representations as an important aspect of scientific literacy. The first project was the development of an exploratory framework that is proposed for use in investigations of students constructing and interpreting multimedia texts. The exploratory framework, which integrates cognition, metacognition, semiotics, and systemic functional linguistics, could eventually result in a model that might be used to guide classroom practice, leading to improved visual literacy, better comprehension of science concepts, and enhanced science literacy because it emphasizes distinct aspects of learning with representations that can be addressed though explicit instruction. The second project was a metasynthesis of the research that was previously conducted as part of the Explicit Literacy Instruction Embedded in Middle School Science project (Pacific CRYSTAL, http://www.educ.uvic.ca/pacificcrystal). Five overarching themes emerged from this case-to-case synthesis: the engaging and effective nature of multimedia genres, opportunities for differentiated instruction using multimodal strategies, opportunities for assessment, an emphasis on visual representations, and the robustness of some multimodal literacy strategies across content areas. The third project was a mixed-methods verification study that was conducted to refine and validate the theoretical framework. This study examined middle school students’ representational competence and focused on students’ creation of visual representations such as labelled diagrams, a form of representation commonly found in science information texts and textbooks. An analysis of the 31 Grade 6 participants’ representations and semistructured interviews revealed five themes, each of which supports one or more dimensions of the exploratory framework: participants’ use of color, participants’ choice of representation (form and function), participants’ method of planning for representing, participants’ knowledge of conventions, and participants’ selection of information to represent. Together, the results of these three projects highlight the need for further research on learning with rather than learning from representations. / Graduate

Thesis (M.F.A.)--Boston University / PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you. / 2031-01-01

The aim of this thesis is to critique two approaches to explaining the relation between representational and phenomenal content. The first approach, representationism, holds that phenomenal content is entirely constituted by intentional or representational content. The second approach, phenomenism, holds that phenomenal content is not entirely constituted by intentional or representational content. There is something ’more’ to phenomenal content than just intentional content. Two types of consideration are considered in order to evaluate these two approaches as follows: The first, considers two ’metaphysical speculations’, inverted spectra and inverted earth: The second, considers causal and explanatory implications of adopting either of these two approaches. Inverted spectrums and inverted earth provide prima facie grounds for rejecting representationism(Block, 1990, 1996; Shoemaker; 199 1); however, it will be demonstrated that both ‘speculations’ do not demonstrate representationism to fail. This thesis will argue that existing responses to inverted earth, for example, Lalor (1999), Lycan (1996), and Tye (1994, 1995b, 1998b) are inadequate. However, it provides a new response to inverted earth on behalf of the wide representationist. Narrow content representationism, which holds that phenomenal contents are functions that map contexts onto contents, will be demonstrated to fail. Doubt is also cast upon teleological approaches to phenomenal content. Causal and explanatory constraints present a problem to both wide representationism and phenomenism. Wide representationalist theories have traditionally faced a challenge from attempting to explain how relational properties can be casually relevant (Fodor, 1987). These problems apply also to representationist theories of phenomenal content. Two current proponents of wide causation are considered, Wilson (1997) and Yablo (1997); their accounts are found to be problematic. Phenomenism either faces a troublesome ‘explanatory gap’ or a problematic commitment to type-type physicalist identity theories. Finally a proposed future direction for these two theories is suggested.

It was 12:51pm on Tuesday the 22nd of February when a 6.2 magnitude earthquake struck the Canterbury region in New Zealand’s South Island. This earthquake devastatingly took the lives of 185 people and caused widespread damage across Christchurch and the Canterbury region. Since the February earthquake there has been 15,832 quakes in the Canterbury region. The impact of the earthquakes has resulted in ongoing social, material and political change which has shaped how everyday life is experienced. While the Christchurch earthquakes have been investigated in relation to a number of different angles and agendas, to date there has been a notable absence on how older people in Christchurch are experiencing post-disaster recovery. This PhD research attends to this omission and by drawing upon geographical scholarship on disasters and ageing to better understand the everyday experiences of post-disaster recovery for older people. This thesis identifies a lack of geographical attention to the emotional, affective and embodied experience of disaster. In response to this the thesis draws upon qualitative material collected from a six months fieldwork period to better understand the ways in which everyday life is lived out in an environment which has been social and materially altered. This thesis identifies three main interrelated themes which are productive for advancing understandings of how older people are situated in a post-disaster context. The first is that the concepts of emotion, affect and embodiment matter as they help inform how disasters are experienced and negotiated and the implication this has on various social and spatial relations. The second is that the disruption of the disaster to everyday places has implications on senses of belonging which is illustrated in highly temporal and affective dimensions. The third theme highlights the importance of recognising mundane and everyday practices as a means of coping and persisting with ongoing impacts of the disaster. This thesis argues that older people should not be seen as passive or homogenous agents in a disaster context but, in fact, are experiencing highly emotional impacts of disaster.

Gene expression analysis has evolved as an extensive toolfor elucidation of various biological and molecular eventsoccurring in different organisms. A variety of techniques andsoftware tools have been developed to enable easier and morerapid means of exploring the genetic information. A moreeffective approach than exploring the whole content of genesexpressed under certain conditions is to study fingerprintassays or to use subtracted cDNA libraries to identify onlydifferentially expressed genes. The objective for the work in this thesis has been toexplore differentially expressed genes in atherosclerosis. Thiswas done by applying and modifying a protocol for thesubtractive approach RDA (Representational Difference Analysis)in different model systems. Initially, the molecular effects of an anti-atheroscleroticdrug candidate were elucidated. In addition, two alternativeapproaches to identify differentially expressed genes obtainedafter iterative rounds of RDA subtraction cycles wereevaluated. This revealed that in most cases, the shotgunapproach in which the obtained gene fragments are clonedwithout any prior selection has clear advantages compared tothe more commonly used selection strategy, whereby distinctbands are excised after gel electrophoresis. A key process in the atherosclerotic plaque initiation isthe phenotypic change of macrophages into foam cells, which canbe triggered in a model system by using macrophages exposed tooxidised LDL. To investigate the genes expressed in thisprocess, the RDA technique was combined with microarrayanalysis, which allows for selectivity and sensitivity throughRDA, as well as rapid high-throughput analysis usingmicroarrays. The combination of these techniques enablessignificant differences in gene expression to be detected, evenfor weakly expressed genes and the results to be reliablyvalidated in a high throughput manner. Finally, investigation of the focal nature ofatherosclerotic lesions and gene expression profiling werestudied using in vivo aortic tissues from ApoE-/- and LDLR -/-mice. The study was based on a comparison between localisationsthat are likely, and others that are unlikely, to developatherosclerotic plaques, and the RDA technique was employed toexplore differential gene expression. <b>Keywords:</b>Representational Difference Analysis,atherosclerosis, gene expression profiling

<p>Gene expression analysis has evolved as an extensive toolfor elucidation of various biological and molecular eventsoccurring in different organisms. A variety of techniques andsoftware tools have been developed to enable easier and morerapid means of exploring the genetic information. A moreeffective approach than exploring the whole content of genesexpressed under certain conditions is to study fingerprintassays or to use subtracted cDNA libraries to identify onlydifferentially expressed genes.</p><p>The objective for the work in this thesis has been toexplore differentially expressed genes in atherosclerosis. Thiswas done by applying and modifying a protocol for thesubtractive approach RDA (Representational Difference Analysis)in different model systems.</p><p>Initially, the molecular effects of an anti-atheroscleroticdrug candidate were elucidated. In addition, two alternativeapproaches to identify differentially expressed genes obtainedafter iterative rounds of RDA subtraction cycles wereevaluated. This revealed that in most cases, the shotgunapproach in which the obtained gene fragments are clonedwithout any prior selection has clear advantages compared tothe more commonly used selection strategy, whereby distinctbands are excised after gel electrophoresis.</p><p>A key process in the atherosclerotic plaque initiation isthe phenotypic change of macrophages into foam cells, which canbe triggered in a model system by using macrophages exposed tooxidised LDL. To investigate the genes expressed in thisprocess, the RDA technique was combined with microarrayanalysis, which allows for selectivity and sensitivity throughRDA, as well as rapid high-throughput analysis usingmicroarrays. The combination of these techniques enablessignificant differences in gene expression to be detected, evenfor weakly expressed genes and the results to be reliablyvalidated in a high throughput manner.</p><p>Finally, investigation of the focal nature ofatherosclerotic lesions and gene expression profiling werestudied using in vivo aortic tissues from ApoE-/- and LDLR -/-mice. The study was based on a comparison between localisationsthat are likely, and others that are unlikely, to developatherosclerotic plaques, and the RDA technique was employed toexplore differential gene expression.</p><p><b>Keywords:</b>Representational Difference Analysis,atherosclerosis, gene expression profiling</p>

It is not uncommon to hear people speak of their worlds coming undone during traumatic events of existential crisis or catastrophe. Yet, human geographers have largely neglected to attend to the phenomenal nature of this unbounded sense of 'unworlding' disintegration, as well as the wild material forces, agencies and passions at loose in the world that carry the unlimited potential to wreck the integrity of our worlds. This dissertation dedicates itself to critically thinking through the human experience of suffering to live through, confront and respond to unworlding disasters of sense that are materially capable of disrupting the functional and relational composition of our worlds. More concretely, in this dissertation I explore unworlding disasters of sense through the specific experiences of agoraphobic sufferers. While social scientists, including human geographers, have long been interested in what is sociologically, spatially and clinically exceptional about agoraphobia as a static predicament of being spatially bounded due to fear of public space, little to no consideration has been given to how agoraphobia primitively and phenomenally manifests itself as an eventful disordering of sense that unsettles not just one's situated place in the world, but the entire relational order of the world itself. By critically attending to agoraphobia as an eventful disordering of sense that improperly deforms the structure of a human world, I seek to develop new ways to account for affective disasters of unworlding that carry the potential to overturn a proper sense of the world. Furthermore, I also speculate on the finite human ability to affirmatively respond to, make sense of, and impose limits on unworlding disasters that exceed one's subjective ability to grasp, yet improperly and materially affect the entire scope of one's lifeworld. In terms of its greater contribution to the discipline of geography, in this dissertation I strive to develop new understandings about the human condition of being in an eventful, material world that infinitely exceeds our ability to subjectively control or understand. By doing so, this dissertation aims to reaffirm the humanistic perspective as a theoretically valid and ethically critical way of practicing geography after the non-representational turn. / text

Η παρούσα διπλωματική εργασία εκπονήθηκε στα πλαίσια του Μεταπτυχιακού Προγράμματος Σπουδών του Παιδαγωγικού Τμήματος Δημοτικής Εκπαίδευσης του Πανεπιστημίου Πατρών και έθεσε ως κεντρικό ζήτημα τη διερεύνηση της ικανότητας που διαθέτουν οι υποψήφιοι μελλοντικοί εκπαιδευτικοί της πρωτοβάθμιας εκπαίδευσης, ως προς τη χρήση των αναπαραστάσεων και ειδικότερα τη χρήση των αναπαραστάσεων στην επίλυση προβλημάτων με κλάσματα. / This paper has been prepared within the Graduate Program of the Department of Education of the University of Patras and has os main issue to investigate the representational competence of pre-service teachers, and particularly the use of representations to solve problems with fractions.

abstract: Geography, and the social sciences more broadly, have long operated within what is arguably a paradigm of the visual. Expanding the reach of geographical consideration into the realm of the aural, though in no way leaving behind the visual, opens the discipline to new areas of human and cultural geography invisible in ocular-centric approaches. At its broadest level, my argument in this dissertation is that music can no longer be simply an object of geographical research. Re-conceptualized and re-theorized in a geographical context to take into account its very real, active, and more-than-representational presence in social life, music provides actual routes to geographic knowledge of the world. I start by constructing a theoretical framework and methodological approach for studying music beyond representation. Based on these theoretical and methodological arguments, I present four narratives that unfold at the intersections of race and music in the northeast Brazilian city of Salvador. From the favelas of Rio de Janeiro to the troubled neighborhood of the Pelourinho, from the manic tempos of samba to the laid back grooves of samba-reggae, and in the year-round competition between the oppressive forces of ordinary time and the fleeting possibility of carnival, music emerges as a creative societal force with affects and effects far beyond the realm of representation. Together, these narratives exemplify the importance of expanding geographical considerations beyond a strictly visual framework. These narratives contribute to the musicalization of the discipline of geography. / Dissertation/Thesis / Ph.D. Geography 2011