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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
241

The miR-51 family of miRNAs is required for the maintenance of pharyngeal attachment in Caenorhabditis elegans

Shaw, William Robert January 2010 (has links)
No description available.
242

Statistical analysis of small RNA high-throughput sequencing data

Woolford, Julie Ruth January 2012 (has links)
No description available.
243

Computational studies on the biogenesis and function of small non-coding RNAs

Bartonicek, Nenad January 2013 (has links)
No description available.
244

Analysis of novel mutants affecting RNA localisation during Drosophila oogenesis

Wheatley, Lucy Eleanor January 2011 (has links)
No description available.
245

A role for the microRNA-210 in the immune system

Schwierzeck, Vera Isabelle January 2011 (has links)
No description available.
246

RNA interference to study host factors required for human immunodeficiency virus-1 replication

Lee, Natasha Chun Yi January 2012 (has links)
No description available.
247

A comparison of chloroplast ribosomal RNA nucleotide sequences of tobacco

Vacek, Ann Elizabeth Treece, 1951- January 1977 (has links)
No description available.
248

Accuracy of TransferRNA Selection in Protein synthesis / Accuracy of TransferRNA Selection in Protein synthesis

Bhutia, Pema choden January 2011 (has links)
ACCURACY OF TRANSFER RNA SELECTION IN PROTEIN SY The ribosome is a rapid magnificent molecular machine that plays an important role in proteinsynthesis and it consists of RNA and protein. The 70S bacterial ribosome comprises twosubunits, 30S and 50S. The 30S small subunit of the bacterial ribosome contains a protein calledS12, encoded by the rpsL gene. The function of this S12 protein is to help arrange the mRNAcorrectly to the ribosome and to interact with transfer RNA (tRNA) to initiate translation.Mutations in the rpsL gene generate phenotypes like resistance, dependence or pseudodependenceto the antibiotic streptomycin in bacteria. It is believed that mutations in the rpsLgene can increase the accuracy of tRNA selection in protein synthesis.The ribosome conducts the selection of tRNA in two steps: the initial selection and theproofreading step. During these multiple steps, the ribosome chooses the cognate aminoacyltRNAsin a ternary complex with EF-Tu and GTP and accommodates in the A site of ribosome.Therefore, the accuracy of the ribosome in selection of cognate aminoacyl-tRNA is crucial for the production of functional polypeptide sequences. Here, three different Escherichia coli strains; wild type MG1655, streptomycin restrictive (SmR) strain res222, and a streptomycin pseudo-dependent (SmP) strain w3110 are used, for studying the accuracy of tRNA selection inprotein synthesis. The mutant SmR shows hyper-accurate phenotype, which means, it has lowerpeptide bond formation efficiency and higher accuracy than the wild type. SmP shows pseudodependentto streptomycin phenotype which means it has higher peptide bond formation efficiency in the presence of antibiotic streptomycin. I have estimated the accuracy of tRNA selection in protein synthesis with enzyme kinetics. The kinetics data of these experiments display that mutant streptomycin restrictive is hyper-accurate and lower peptide bond formation efficiency than the wild type. SmP for the near cognate reaction in presence of antibiotic streptomycin has higher peptide bond formation efficiency than the SmP in absence of antibiotic streptomycin. SmP in presence antibiotic streptomycin has lower accuracy than the SmP in absence of antibiotic streptomycin.
249

A kinetic study of the interaction of T7 RNA polymerase with its natural promoters

Clarke, Jane 05 1900 (has links)
No description available.
250

Genetic studies of self-splicing RNAs in bacteriophage T4

Deyoung, Katherine Leigh 12 1900 (has links)
No description available.

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