The purpose of this thesis was to study the outcome of Single Event Multilevel Surgery (SEMLS) on the gait pattern known as crouch gait in children with spastic diplegic cerebral palsy. The term “crouch gait” in the literature has been defined by many authors to mean a flexed knee coupled with many different combinations of posture at the ankle. Consequently it was necessary to provide a robust definition of crouch gait before the outcome study could proceed. Crouch gait was defined in the context of a classification of sagittal gait patterns in spastic diplegia. In the cross-sectional study on the classification of sagittal gait patterns, 187 children with spastic diplegia were categorised according to visual recognition of their gait pattern and sagittal plane kinematic data. Six gait patterns in spastic diplegia were identified, one of which was crouch gait. A pattern of increasing age, severity and biomechanical incompetency in maintaining an extended posture was seen across the gait patterns and crouch gait appeared to be the “end” gait pattern. A longitudinal study documented how the identified gait patterns evolved over time. Thirty-four children were followed for more than one year and the results indicated that the stability of the gait pattern was variable. The reliability of the classification was found to be acceptable. (For complete abstract open document)

A relação entre a anatomia mandibular e a ocorrência de fratura indesejada de mandíbula na osteotomia sagital é alvo de estudos. A literatura mostra a existência de diferentes conformações anatômicas da mandíbula, porém não há estudos nessa área direcionados a indivíduos com fissura labiopalatina. Também não há na literatura estudos que mostrem as diferenças morfológicas da mandíbula relacionadas a secção transversal entre primeiro e segundo molar e sua relação com implicações na cirurgia ortognática. O objetivo do presente estudo foi avaliar a morfologia da região entre primeiro e segundo molar inferior e classificar a prevalência dos tipos mandibulares dentro de cada grupo. Foram realizadas análises e medições das reformatações das tomografias da região de molares, bilateralmente, de indivíduos Classe III, com fissura labiopalatina unilateral (Grupo FLP) submetidos à cirurgia ortognática para recuo mandibular no Hospital de Reabilitação de Anomalias Craniofaciais e de indivíduos Classe III, sem fissura (Grupo Controle) do banco de dados do Departamento de Cirurgia e Estomatologia da Faculdade de Odontologia de Bauru. Foram realizadas duas medidas lineares e uma medida angular. As hemimandíbulas foram classificadas segundo a profundidade da fossa mandibular em: Tipo a - 0 e 1mm; Tipo b - 1,1 e 2mm; Tipo c - 2,1 e 3mm; Tipo d - maior que 3,1mm. Foram analisadas 200 hemimandíbulas no Grupo FLP e 100 no Grupo Controle. Os resultados mostraram que não houve diferença entre os grupos quanto a classificação das mandíbulas segunda a profundidade da fossa, sendo o grupo b o mais prevalente, mas houve diferença em relação a angulação e a altura da mandíbula . Também foi notada uma relação entre a altura da mandíbula e a sua angulação em ambos os grupos. Assim, pode ser observada a grande variação morfológica dessa região, tanto para o grupo com fissura labiopalatina, quanto para o grupo controle. / The relationship between a mandibular anatomy and an occurrence of an undesirable jaw fracture in a sagittal osteotomy is the subject of the studies. The literature shows an existence of different anatomical conformations of the mandible, but there are no studies on the area directed to individuals with cleft lip and palate. There are not in the literature, studies that show a prevalence of mandibular types and the relation of these anatomical variations with orthognathic surgery implications. The objective of the present study was evaluate the morphology of the region between the first and second lower molars and analyze the prevalence of mandibular types within each sample group. Analyzes and measurements of the CT scans were performed bilaterally on Class III patients with unilateral cleft lip and palate (CLP Group) submitted to orthognathic surgery for mandibular retreatment at the Hospital for Rehabilitation of Craniofacial Anomalies and Class III individuals, without Fissure (Control Group) of the database of the Department of Stomatology of the Faculty of Dentistry of Bauru. Two linear measurements and one angular measurement were performed. The half of mandibles were classified according to the depth of the mandibular fossa in: Type a - 0 and 1mm; Type b - 1.1 and 2mm; Type c - 2.1 and 3 mm; Type d - greater than 3.1mm. Two hundred half of mandibles were analyzed in the CLP Group and 100 in the Control Group. The results showed that there was no difference between the groups regarding the classification of the mandibles according to the depth of the fossa, being group b the most prevalent, but there was difference in relation to the angulation and the height of the mandible. It was also noted a relationship between the height of the mandible and its angulation in both groups. Thus, the great anatomical variation of this region can be observed, both for the group with fissure and for the group without fissure.

Title: Influence of gait in high heels on posture, and division of pressure on the contact area level of the feet and the floor Objective: The aim of the dissertation was to verify how walking in high-heeled shoes influences the time and pressure parameters of the step cycle and posture during slow and very slow walking in low experienced wearers. Methods: The research study was an empirical, comparative intra-individual study. Pedar-X® measuring inserts (Novel, Munich, Germany) were used to measure the distribution of plantar pressures and to evaluate time parameters while walking on a conveyor belt at v1 = 0.97 ms-1 and v2 = 0.56 ms-1 in straight shoes and high-heeled shoes. SonoSens Monitor Analyzer® (Gefremed, Chemnitz, Germany) was used to assess posture. The research group consisted of thirty healthy women wearing high-heeled shoes occasionally (age: 21.8 ± 2.09 years, weight: 55.7 ± 4.05 kg, height: 1.66 ± 0.03 m). Anova test and paired t-test were used for statistical analysis, and the Cohen coefficient d was used to calculate material significance. Results: Significant differences in time and plantar pressure variables were found when walking in high-heeled shoes compared to straight footwear. For both types of footwear, walking speed only affected time variables, but not dynamic...

Title: Influence of gait in high heels on posture, and division of pressure on the contact area level of the feet and the floor. Objective: The aim of the dissertation was to confirm how walking in high-heeled shoes influences the time and pressure parameters of the step cycle and posture during slow and very slow walking in low experienced wearers. Methods: The research study was an empirical, comparative intra-individual study. Pedar-X® measuring inserts (Novel, Munich, Germany) were used to measure the distribution of plantar pressures and to evaluate time parameters while walking on a conveyor belt at v1 = 0.97 ms-1 and v2 = 0.56 ms-1 in straight shoes and high-heeled shoes. SonoSens Monitor Analyzer® (Gefremed, Chemnitz, Germany) was used to assess posture. The research group consisted of thirty healthy women wearing high-heeled shoes occasionally (age: 21.8 ± 2.09 years, weight: 55.7 ± 4.05 kg, height: 1.66 ± 0.03 m). Anova test and paired t-test were used for statistical analysis, and the Cohen coefficient d was used to calculate material significance. Results: Significant differences in time and plantar pressure variables were found when walking in high-heeled shoes compared to straight footwear. For both types of footwear, walking speed only affected time variables, but not dynamic...

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Introduction : La scaphocéphalie est la craniosynostose monosuturaire la plus commune (1/2000). Celle-ci est causée par la fusion prématurée de la suture sagittale. Une chirurgie corrective de la voûte crânienne peut être effectuée dans la première année de vie de l’enfant. Il n’existe actuellement aucune donnée précise dans la littérature scientifique étudiant l’occlusion chez les patients scaphocéphales, ainsi que les impacts potentiels de la chirurgie de la voûte crânienne sur celle-ci. Objectifs : L’objectif primaire de cette étude est de décrire et comparer la malocclusion dento-squelettique d’un groupe de patients scaphocéphales à une population pédiatrique normale. L’objectif secondaire est d’évaluer la différence au niveau de l’occlusion entre un sous-groupe de patients scaphocéphales ayant eu une chirurgie corrective de la voûte crânienne et un sous-groupe ne l’ayant pas eu. Méthodologie : Quatre-vingt-onze patients scaphocéphales (2-11 ans; 71 garçons) de la banque de données de la Clinique de Craniofacial du CHU Ste-Justine ont formé le groupe expérimental. Tous les patients ont eu un examen orthodontique complet et ont été suivis. Parmi ceux-ci, quarante-quatre avaient eu une chirurgie corrective de la voûte crânienne et quarante-sept n’en avaient pas eu, mais étaient suivis régulièrement à la clinique. Trente-huit (33 garçons; 17 opérés) de ces patients ont eu des radiographies céphalométriques latérales et parmi ceux-ci, un certain nombre ont reçus des suivis de croissance radiologiques. Résultats : Les valeurs cliniques de la classification dentaire, ainsi que la mesure du surplomb horizontal, ont indiqué une augmentation de la prévalence de malocclusions de classe II chez les enfants scaphocéphales. Par contre, les valeurs céphalométriques indicatrices de malocclusion squelettique de classe II (ex. : N-A perp HP, N-B perp HP, N-Pog perp HP, Wits, N-A-Pog) sont demeurées dans les limites de la normale. Certaines valeurs céphalométriques présentent une différence statistiquement significative entre les patients opérés et non opérés (ANS-PNS t2, p=0.025; /1-FH t2, p=0.028), mais ces variations individuelles ne sont pas reliées à la scaphocéphalie. Conclusion : Les enfants scaphocéphales présentent cliniquement davantage de malocclusions de classe II que les enfants normaux. Par contre, les valeurs radiologiques antéro-postérieures et transverses demeurent dans les limites de la normale. La chirurgie corrective de la voûte crânienne n’affecte également pas l’occlusion chez ces patients. / Introduction: Scaphocephaly, the most common unisutural craniosynostosis (1/2000), results from a premature fusion of the sagittal suture. Usually, cranial vault corrective surgery is performed during the first year of life. There is currently no scientific data regarding occlusion of scaphocephalic patients, or the potential effect of craniovault surgery on the occlusion. Objectives: The primary objective of this study is to describe occlusion in scaphocephalic patients and to compare with a general pediatric population matched for age and gender. The second objective is to compare the difference in occlusion of surgically treated scaphocephalic subgroup versus unoperated scaphocephalic subgroup. Methods: Ninety-one scaphocephalic patients (2-11 y.o.; 71 boys) from the craniofacial clinic of CHU Ste-Justine’s database formed our experimental group. All patients received an orthodontic assessment and were followed up. Among them, forty-four underwent craniovault surgery while forty-seven remained unoperated. Thirty-eight (33 boys; 17 operated) had lateral cephalometric radiographies, some of whom also had cephalometric growth follow-ups. Results: Clinical values for dental classification and overjet indicate an increased prevalence of class II malocclusions in scaphocephalic patients. However, cephalometric values indicative of skeletal class II malocclusions (i.e. N-A perp HP, N-B perp HP, N-Pog perp HP, Wits, N-A-Pog) remained within normal limits. Some cephalometric values present statistically significant differences between operated and unoperated patients (ANS-PNS t2, p=0.025; /1-FH t2, p=0.028), but these are individual variations not related to scaphocephaly. Conclusion: Scaphocephalic patients clinically present more class II malocclusions when compared with normal children. Radiographic values remain however within normal limits for both antero-posterior and transverse dimensions. Corrective craniovault surgery does not affect occlusion in these patients.

Le cerveau humain est une structure anatomique à symétrie bilatérale : il existe un plan, appelé plan médian sagittal, par rapport auquel il est (approximativement) symétrique. Certaines structures ou aires cérébrales sont pourtant systématiquement asymétriques. L'étude de ces asymétries et de leurs anomalies est d'un intérêt majeur pour la compréhension de certaines pathologies comme la schizophrénie. Dans cette thèse, nous présentons une méthode permettant de quantifier ces déviations locales par rapport à une symétrie bilatérale parfaite et d'en effectuer une analyse statistique dans des populations de sujets. En raison du positionnement arbitraire de la tête dans l'appareil d'acquisition, le plan médian sagittal est rarement situé au centre des images médicales tridimensionnelles anatomiques (IRM, scanner) ou fonctionnelles (TESP, TEP). Nous proposons une définition objective de ce plan, fondée sur un critère mathématique robuste de type moindres carrés tamisés. Ensuite, après calcul et réalignement du plan médian sagittal, nous montrons comment obtenir en chaque point de l'image un vecteur caractéristique de l'asymétrie de la structure anatomique sous-jacente. Ce champ d'asymétrie est obtenu au moyen d'un outil de recalage non-rigide, qui est également utilisé pour fusionner dans un référentiel géométrique commun les champs calculés sur une population d'individus. Des techniques statistiques classiques (de type test de Hotteling) permettent alors d'étudier l'asymétrie d'une population ou de comparer l'asymétrie entre deux populations. Un problème spécifique aux IRM est celui des variations lentes des intensités de l'image, induites par les interactions du sujet avec le champ magnétique, et qui ne reflétent pas les propriétés physiques des tissus sous-jacents. La structure géométrique de ce champ de biais est elle-même asymétrique, et perturbe substantiellement le calcul de l'asymétrie anatomique. Nous proposons différents algorithmes pour corriger ce biais, fondés sur des modélisations mathématiques du processus d'acquisition de l'image.

Introduction : La scaphocéphalie est la craniosynostose monosuturaire la plus commune (1/2000). Celle-ci est causée par la fusion prématurée de la suture sagittale. Une chirurgie corrective de la voûte crânienne peut être effectuée dans la première année de vie de l’enfant. Il n’existe actuellement aucune donnée précise dans la littérature scientifique étudiant l’occlusion chez les patients scaphocéphales, ainsi que les impacts potentiels de la chirurgie de la voûte crânienne sur celle-ci. Objectifs : L’objectif primaire de cette étude est de décrire et comparer la malocclusion dento-squelettique d’un groupe de patients scaphocéphales à une population pédiatrique normale. L’objectif secondaire est d’évaluer la différence au niveau de l’occlusion entre un sous-groupe de patients scaphocéphales ayant eu une chirurgie corrective de la voûte crânienne et un sous-groupe ne l’ayant pas eu. Méthodologie : Quatre-vingt-onze patients scaphocéphales (2-11 ans; 71 garçons) de la banque de données de la Clinique de Craniofacial du CHU Ste-Justine ont formé le groupe expérimental. Tous les patients ont eu un examen orthodontique complet et ont été suivis. Parmi ceux-ci, quarante-quatre avaient eu une chirurgie corrective de la voûte crânienne et quarante-sept n’en avaient pas eu, mais étaient suivis régulièrement à la clinique. Trente-huit (33 garçons; 17 opérés) de ces patients ont eu des radiographies céphalométriques latérales et parmi ceux-ci, un certain nombre ont reçus des suivis de croissance radiologiques. Résultats : Les valeurs cliniques de la classification dentaire, ainsi que la mesure du surplomb horizontal, ont indiqué une augmentation de la prévalence de malocclusions de classe II chez les enfants scaphocéphales. Par contre, les valeurs céphalométriques indicatrices de malocclusion squelettique de classe II (ex. : N-A perp HP, N-B perp HP, N-Pog perp HP, Wits, N-A-Pog) sont demeurées dans les limites de la normale. Certaines valeurs céphalométriques présentent une différence statistiquement significative entre les patients opérés et non opérés (ANS-PNS t2, p=0.025; /1-FH t2, p=0.028), mais ces variations individuelles ne sont pas reliées à la scaphocéphalie. Conclusion : Les enfants scaphocéphales présentent cliniquement davantage de malocclusions de classe II que les enfants normaux. Par contre, les valeurs radiologiques antéro-postérieures et transverses demeurent dans les limites de la normale. La chirurgie corrective de la voûte crânienne n’affecte également pas l’occlusion chez ces patients. / Introduction: Scaphocephaly, the most common unisutural craniosynostosis (1/2000), results from a premature fusion of the sagittal suture. Usually, cranial vault corrective surgery is performed during the first year of life. There is currently no scientific data regarding occlusion of scaphocephalic patients, or the potential effect of craniovault surgery on the occlusion. Objectives: The primary objective of this study is to describe occlusion in scaphocephalic patients and to compare with a general pediatric population matched for age and gender. The second objective is to compare the difference in occlusion of surgically treated scaphocephalic subgroup versus unoperated scaphocephalic subgroup. Methods: Ninety-one scaphocephalic patients (2-11 y.o.; 71 boys) from the craniofacial clinic of CHU Ste-Justine’s database formed our experimental group. All patients received an orthodontic assessment and were followed up. Among them, forty-four underwent craniovault surgery while forty-seven remained unoperated. Thirty-eight (33 boys; 17 operated) had lateral cephalometric radiographies, some of whom also had cephalometric growth follow-ups. Results: Clinical values for dental classification and overjet indicate an increased prevalence of class II malocclusions in scaphocephalic patients. However, cephalometric values indicative of skeletal class II malocclusions (i.e. N-A perp HP, N-B perp HP, N-Pog perp HP, Wits, N-A-Pog) remained within normal limits. Some cephalometric values present statistically significant differences between operated and unoperated patients (ANS-PNS t2, p=0.025; /1-FH t2, p=0.028), but these are individual variations not related to scaphocephaly. Conclusion: Scaphocephalic patients clinically present more class II malocclusions when compared with normal children. Radiographic values remain however within normal limits for both antero-posterior and transverse dimensions. Corrective craniovault surgery does not affect occlusion in these patients.

Orientador: Marisa Aparecida Cabrini Gabrielli / Resumo: Este estudo avaliou o padrão da separação da osteotomia sagital do ramo mandibular, sob o aspecto lingual e a influência da espessura óssea correlacionando a esse padrão. Para tanto, foram selecionadas tomografias pré e pós-operatórias de 31 pacientes com deformidade dento-esquelética facial que haviam sido submetidos a tratamento ortodôntico-cirúrgico para correção de deformidade facial dento-esquelética. As tomografias foram analisadas utilizando o software Dolphin 3D 11.8. Foram avaliadas 62 osteotomias sagitais do ramo mandibular (OSRM). Nos exames tomográficos pré-operatórios foram consideradas 4 medidas de espessura no sentido vestíbulo lingual, em áreas pré determinadas da osteotomia: Região A - 1,5mm acima da língula mandibular, Região B - 1mm distante da borda anterior de ramo (Região A e B na altura da osteotomia medial), Região C - 5mm distalmente ao segundo molar e 5mm a partir da borda superior (região retromolar) Região D - região de entre as raízes distal e mesial do 1º e 2º molares inferiores, distando 5 mm da base inferior da mandíbula. Nos exames pós-operatórios, foi analisado o padrão de fratura gerada, classificado em padrão I, II, III ou IV, conforme classificação de Plooij et al. Os dados coletados foram analisados pelo teste estatístico de Kruskal-Wallis seguido do pós-teste de Dunn. Foram encontradas 35 fraturas com padrão tipo I; 01 fratura padrão tipo II; 19 do padrão tipo III e 07 fraturas de padrão tipo IV. O padrão I obteve as maiores médias de es... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: This study evaluates the split pattern after sagittal split ramus osteotomy and its correlation with the bone thickness. Pre and postoperative computed tomographies of 31 patients submitted to orthognathic surgery for corrections of dentofacial deformities were used in the study. Dicom images were analyzed using the software Dolphin 3D 11.8. In the preoperative tomographies 4 thickness measurements were considered: A - 1.5 mm above the lingula. B - 1mm from the anterior border of the ramus (A and B points at the height of the medial osteotomy cut). C - 5mm distally to the second molar and 5mm from the upper border of the mandible (retromolar region) D - In the region between the mesial and distal roots of the first and second mandibular molars. In the postoperative tomographies the exams were analyzed and classified according to the fracture pattern described in the literature, where I (true Hunsuk), II (posterior cortical of the branch), III (through the mandibular canal) and IV (bad split). The data were analyzed by the Kruskal-Wallis test followed by the Dunn post-test. Results showed 35 type I fractures, 01 type II fracture, 19 type III fractures and 07 type IV fractures. Type I presented the highest thickness average values for the four considered measurements, whereas type IV presented the lowest values for all measurements. The variable bone thickness was statistically significant only for point A, when the types I and IV were compared. Results allowed to conclude that... (Complete abstract click electronic access below) / Mestre

Orientador: Marisa Aparecida Cabrini Gabrielli / Resumo: Considerando a variável anatomia como um possível fator de risco para o desenvolvimento de fraturas indesejadas após a osteotomia sagital do ramo mandibular (OSRM), este estudo avaliou a influência da espessura óssea sob o padrão de fratura entre os seguimentos proximal (contendo o côndilo) e distal (contendo o processo alveolar) após a OSRM. Para tanto, foram selecionadas tomografias pré e pós-operatórias de 31 pacientes (62 OSRM) com deformidade dento-esquelética-facial com tratamento ortodôntico-cirúrgico prévio. As tomografias foram analisadas utilizando o software Dolphin 3D 11.8. Nos exames pré-operatórios considerou-se 4 medidas da espessura óssea no sentido vestíbulo-lingual, em áreas pré determinadas da OSRM: Região A - 1,5 milímetros (mm) acima da língula mandibular, Região B - 1mm distante da borda anterior de ramo (Região A e B na altura da osteotomia medial), Região C - 5mm distalmente ao segundo molar e 5mm a partir da borda superior (região retromolar) Região D - região de entre as raízes distal e mesial do 1º e 2º molares inferiores, distando 6 mm da base inferior da mandíbula. Nos exames pós-operatórios, analisou-se o padrão de fratura gerado, classificando-o em I (Hunsuck verdadeiro), II (cortical posterior), III (através do canal mandibular) ou IV(fratura indesejada), conforme classificação de Plooij et al. Após teste de normalidade, os dados foram analisados pelo teste estatístico não paramétrico de Kruskal-Wallis seguido do pós-teste de Dunn. Encontrou-se... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Considering the variable anatomy as a possible risk factor for the development of undesirable fractures after bilateral sagittal split osteotomy (BSSO). This study evaluates the split pattern after BSSO and its correlation with the bone thickness. Pre and postoperative computed tomographies of 31 patients (62 BSSO) submitted to orthognathic surgery for corrections of dentofacial deformities were used in the study. Dicom images were analyzed using the software Dolphin 3D 11.8. In the preoperative tomographies 4 thickness measurements were considered: A - 1.5 milimeter (mm) above the lingula. B - 1mm from the anterior border of the ramus (A and B points at the height of the medial osteotomy cut). C - 5mm distally to the second molar and 5mm from the upper border of the mandible (retromolar region) D - In the region between the mesial and distal roots of the first and second mandibular molars. In the postoperative tomographies the exams were analyzed and classified according to the fracture pattern described in the literature, where I (true Hunsuk), II (posterior cortical of the branch), III (through the mandibular canal) and IV (bad split). The data were analyzed by the Kruskal-Wallis test followed by the Dunn post-test. Results showed 35 type I fractures, 01 type II fracture, 19 type III fractures and 07 type IV fractures. Type I presented the highest thickness average values for the four considered measurements, whereas type IV presented the lowest values for all measurements... (Complete abstract click electronic access below) / Mestre