Made available in DSpace on 2018-08-01T23:40:37Z (GMT). No. of bitstreams: 1 tese_9080_Celia_Bubach_versao_final.pdf: 1644535 bytes, checksum: dd7a0dff0eb4859006b68f2adfaded57 (MD5) Previous issue date: 2015-07-15 / O objetivo desse estudo foi investigar o processo de mudança no sistema de controle gerencial (SCG), analisando a alteração das práticas de controle gerencial na estrutura desse sistema, sob a ótica da teoria institucional. A questão de pesquisa é: como ocorre o processo de mudança no SCG em uma organização industrial brasileira? Para tanto, optou-se por uma abordagem qualitativa do tipo descritiva, num estudo de caso único, utilizando como métodos de coleta de dados entrevistas individuais não estruturadas e semiestruturadas com 11 gestores e usuários do SCG, observação não participante e levantamento documental. A coleta dos dados ocorreu entre agosto/2014 e março/2015. Como método de análise e interpretação de dados foram utilizados elementos da análise do discurso (AD). Os principais referenciais teóricos foram os trabalhos de Meyer e Rowan (1977), Dimaggio e Powel (1983, 1991, 2007), Scott (1995, 2008a, 2008b) e Machado-da-Silva e Vizeu (2007) sobre a teoria institucional; Huy (2001), Beekman, Chenhall e Euske (2007) e Machado-da-Silva, Fonseca e Crubellate (2010) referente ao processo de mudança; e Malmi e Brown (2008) e Simons (1995) referente ao SCG; destacando a aplicação empírica dos modelos teóricos de Malmi e Brown (2008), Simons (1995) e Huy (2001). Na análise dos dados, foi identificado o desenho e o uso do SCG, relatando como está transcorrendo a alteração de suas práticas de controle gerencial, identificando os fatores de estímulo e resistência à institucionalização dessas práticas e quais os atores organizacionais que estão atuando como agentes da mudança. Por fim, foram identificados os aspectos discursivos recorrentes que permeiam o discurso da empresa pesquisada, alinhados ao processo de mudança no SCG. Como contribuições, foi demonstrada a influência dos fatores isomórficos na escolha das práticas de controle gerencial, a evidência de que o SCG é socialmente construído, as implicações da centralização do poder e da ausência de estratégias para o SCG, evidências de que o processo de mudança no SCG não é meramente mecânico ou automatizado e ainda, que o discurso da mudança pode permear a organização sem que a ação seja concretizada, revelando um descompasso entre o discurso e a ação.

This thesis deals with the relation between structure and resistance to failure by the mechanism of slow crack growth (SCG) in HDPE. In the theoretical part there are summarized previously acquired knowledge about the production of PE and about the relation between structure and resistance to failure by the SCG mechanism. In the experimental part, three samples of HDPE with the same melt index MI and the same content of copolymer 1- hexene were synthesized by using three chromium catalysts commonly used for polymerization in industry. There samples were analyzed by GPC-IR-MALS and TREF in order to determine the distribution of side chain branches. The results were discussed with respect to the time to failure FNCT.

Serotoninergic type 3 receptors (5HT3Rs) are members of the Cys-loop family of ligand-gated ion channels (LGIC), which includes nicotinic ACh, glycine, GABA-A and GABA-C receptors. All members of this family are widely expressed in the central and peripheral nervous systems, where they mostly participate in fast synaptic transmission. Activation of 5HT3Rs on vagal sensory nerve endings affect respiration, circulation, emesis and nociception; and in the central nervous system they are implicated in anxiety, depression, and drug dependence. In contrast, the function of 5HT3Rs in sympathetic neurons has not been fully determined. We discovered that 5HT3Rs interact with nicotinic acetylcholine receptors (nAChRs), the main drivers of the fast cholinergic autonomic synapse, through cross-talk mechanisms. We examined cross-talk by the patch-clamp technique on cultured mouse superior cervical ganglia (SCG) neurons. Co-stimulation of 5HT3Rs and nAChRs resulted in the generation of a combined current that was smaller than arithmetically predicted if the receptors did not interact with one another. This interaction, which we quantified as mean peak amplitude and mean ionic charge, was dependent on activation of 5HT3Rs and nAChRs, and independent of metabotropic receptors, Ca2+ entry and Ca2+ second messenger pathways, and of the direct action of 5HT on nAChRs. Preliminary data using an antibody targeted to the M3-M4 linker region of the 5HT3A subunit revealed that 5HT3Rs and nAChRs possibly cross-talk through physical interactions. These results revealed a potential role of the 5HT3R in the regulation of sympathetic synaptic transmission through cross-talk inhibition of nAChRs.

The theoretical part of the thesis deals with the summary of material properties and testing parameters that influence SCG process. The experimental part is aimed on the comparison of different condition effects on the process of FNCT and PENT. Chosen temperatures for PENT were 70; 80 and 90 °C and the applied nominal stress 2,0; 2,4 and 2,8 MPa. In the case of FNCT the chosen temperatures were the same and the ligamental stress was 4 MPa for all used environments which were: water, Arkopal N110 solution and Dehyton PL solution. In addition, several experiments were measuered under applied nominal stresses 3; 4; 5; 6; 8 a 10 MPa and at 80 °C in Arkopal N110 solution. The morphology of crack surfaces was studied afterwards. The obtained data were used for evaluaion by a five parameter equation.

No description available.

Denna projektrapport är avsedd att vara ett hjälpmedel för SiCell, en del av SciLifeLab Uppsala som ska bli Europas första plattform för enkelcellgenomik till hösten 2013. SiCell har bett projektgruppen om undersökningar gällande ett Laboratory Information Management System, LIMS. På svenska ett datahanteringsystem för laboratorier. Ett sådant system skulle kunna effektivisera SiCells verksamhet. Undersökningarna har resulterat i en kravspecifikation som ett LIMS för SiCell ska uppfylla och en sammanställning av tillgängliga mjukvaror som bäst uppfyller dessa krav. Screensaver, MISO och Gnomex är de tre gratisprogram med öppen källkod som hamnade högst upp i listan. Inget av dem uppfyller alla krav men med modifieringar av programmerare tros detta vara möjligt. SiCell bad också om lägre prioriterade undersökningar av några av de metoder som används inom plattformen. Cellysering, Alternativa amplifieringsmetoder och transkriptomik har undersökts av projektgruppen. Detta resulterade i en sammanställning av vilka alternativ som finns och vad som är under utveckling inom respektive område.

The intent of this thesis is to lay groundwork for examining the relationship between seismocardiography (SCG) and phonocardiography (PCG). Both are methods of measuring and describing heart mechanical function. SCG is described as chest vibrations while the heart beats, and PCG is described as acoustic chest surface signal believed to represent the heart valves opening or closing. SCG and PCG have both been used separately in clinical and research settings, but there is currently no clear comparison between the two. Therefore, there has been no way at the present to understand how one signal might inform the other. This study is an effort to fill that gap. SCG and PCG sensors were placed on subjects’ chests while sensor output was simultaneously recorded. The magnitudes of the signals and their trends were then compared against each other to see their similarities and differences. The comparisons demonstrated similar trends between the two sensor types, supporting the hypothesis that there is a relationship between the two that requires further research and insight.

No description available.

This paper examines an overview of the economic and environmental aspects of Underground Coal Gasification (UCG) as a viable option to the above ground Surface Coal Gasification (SCG). In addition, some highlights, hurdles and opportunities from early investment to successful commercial application of some worldwide UCG projects will be discussed. Global energy demands have prompted continual crude oil consumption at an astronomical pace. As such, the most advanced economies are looking for local and bountiful resources to challenge crude oil's dependence for which coal provides the best alternative so far. In the U.S, the Department of Energy (DOE), the National Energy Transportation Laboratory (NETL) along with the Lawrence Livermore National Laboratory (LLNL) continue to support pilot programs that develop improved methods for clean coal technologies to produce coal derived fuels competitive with crude oil fuels at about $30 per barrel. Lignite, the softest of the four types of coal, is the best candidate for underground coal gasification due to its abundance, high volatility and water to carbon content in its rock formation. The biggest challenge of modern humans is to find a balance of energy consumption, availability of resources, production costs and environmental conservation. Additionally, UCG has environmental benefits that include mitigating CO₂ emissions through Carbon Capture and Storage (CCS) and reduced overall surface pollutants, making it the preferred choice over SCG. / text

Didelė dalis širdies susirgimų diagnostinių kriterijų gaunama registruojant ir analizuojant kardiosignalus, kurie atspindi tiek elektrinės širdies veiklos sutrikimus (EKG), tiek ir hemodinaminės bei mechaninės veiklos pokyčius, t.y. impedanskardiograma (IKG) ir seismokardiograma (SKG). Dar daugiau, efektyvus širdies susirgimų diagnostikos problemų sprendimas yra naujų kardiosignalų analizės technologijų kūrimas. Jau kelis dešimtmečius Furjė transformacija taikoma EKG dažnumų analizei, tuo tarpu kai IKG ir SKG dažnio charakteristikų vertinimui šis metodas nebuvo naudojamas. Darbo tikslas buvo pritaikyti Furjė analizę įvertinant bei palyginant tris sinchroniškai užregistruotus kardiosignalus, nes jie atspindi elektrinės širdies, hemodinaminės bei mechaninės širdies veiklos pokyčius geriau nei vienas EKG signalas. Kitas darbo tikslas buvo pritaikyti Furjė analizę įvertinant bei palyginant trijų sinchroniškai užregistruotų signalų - EKG, IKG ir SKG dažnio charakteristikas ir koherenciją bei klasifikuoti dvi grupes - "sveikas" ir "ligonis". Rezultatai rodo, kad koherencijos vertinimas ir spektrinė analizė gali būti naudinga gali būti naudingas širdies kraujagyslių bei plaučių sistemų ligų diagnostikai. / A big part of heart disease diagnostics criteria is collected by registration and analysis of cardio signals that reflect the disturbances of the electric heart activity – electrocardiogram (EСG), changes of hemodynamic - impedance cardiograms (IСG) and mechanic activity - seismocardiogram (SСG). ECG analysis is generally applying in clinic practice, but usually in visual way only. Due to the development of the technologies, the bigger amount of data could be stored and more exact analysis of information could be carried out. Therefore, a solution of problem of effective diagnostics of heart diseases is the creation of new technologies for analysis of cardio signals. Previously Fourier series were applied to frequency analysis of ECG, but this method was not applied for estimation of ICG and SCG frequency characteristics. In this thesis the frequency analysis method was applied to three cardio signals, because they reflect the electrical and mechanical work of the human heart better as entirely ECG signal. The main aim of this work was to adapt Fourier transformation to assessing and comparing some characteristics of hereinbefore signals, such as coherence and classify two searching groups - “healthy” and “sick”. Results showed that rating of coherence and spectral analysis could be useful for rightly analyzing and classifying the searching groups.