The projected retirement home is located in the cadaster of the town Velká Bíteš. The building is designed with respect of resident's needs of retirement age. It is a four-storey building without basement. There are designed external doctor's offices on the first floor. There are lounge with library and technical facilities on the first floor as well. Besides that, we can find accomodation spaces from second up to fourth floor. The structural system is a longitudinal wall and ceilings are made by monolithic reinforced concrete. The roof is shed. The building is detached with built chambers

Subject of the solution master´s thesis is new domestic building. It is two floors building made out of construction system Porotherm with monolithic ferronconcrete ceilings and shed roof. First floor has two versions.In first version is four studio flats. Second version on the first floor is used for accommodation disabled people and there are three apartments and one unit with facilities for carers. Second floor is used for accommodation two smaller families and there are two apartments with entrance from gallerie. Building is located in straight terrain in the development area of new houses in Žatec in area Kamenný vrch.

Diploma thesis is focused on the preparation of the implementation of the University Centre in Zlín. The work includes building technology study and subsequent construction technology project. In this thesis, the aim was to determine the time, financial and material demands of the project, choose the optimum process of construction, ensure BOZP, make the proposal buildingsite for the individual stages, the calculation of costs of site preparation and select adequate mechanical the assembly. It was drafted fire assessments of buildings.

The aim of the Diploma Thesis is a multifuncional building design. The Design Documentation deals with a four-storey multifunctional building. This multifunctional building is separately standing building. The building is designed as a newly constructed four-storey multifuncional building, without basement. The strucural system is desinged in a walled technology of POROTHERM system. Ceilings are made of prestressed concrete ceiling panels. The roof is shed, made of asphalt felts. The house will be founded on monolithic concrete continuous footing strips.

The diploma thesis deals with the design of a kindergarten on a particular building site in the village of Netin. The aim is to create a functional layout suitable for everyday use. It is a two-floor construction without a cellar which can accommodate 40 pre-school children. The building has been designed using the construction software system KM BETA and is sheltered with a flat roof on the one-floor part and with a shed roof on the two-floor part.

The diploma thesis deals with the design of a winery with accommodation facilities. The whole area consists of the main building, a building for storage of garden equipment and wooden cabins for lodging during summer time. The diploma thesis is mostly focused on the design of the main building with the winemaking facilities, five rooms on the second floor and technical background. All buildings in the area are appropriately placed considering the cardinal points and they are logically connected with each other by means of roads. The main building is fully provided with cellars where the largest part of the production and the sampling and presentation rooms are found. The shape of the floor plan displays a shape of the letter “u” with two above-ground floors. The whole second above-ground floor is created as a relaxation zone for the guests. Each room has its private balcony with a nice view of the neighbouring vineyards. The roofing is implemented by the flat roof with extensive vegetation and wooden roof trusses, fitting into the surrounding landscape.

This thesis describes the design of the recreation grounds, which consists of a main building of a restaurant and six holiday cottages. The plot is also a tennis court. The restaurant is a two-storey building without a basement. All the cottages are single storey and cellar. Restaurants device is designed for a maximum capacity of 70 people. Total capacity of the entire complex is 30 beds. The restaurant is focused on the northern part of the land and buildings of six holiday cottages on the south side. Restaurant is designed as a brick structure with a contact insulating system. Partitions are designed as plasterboard. The ceiling is designed as a monolithic reinforced concrete slab. Part of the roof is designed as a pitch roof truss recognized. The largest area of flat roof occupies roof vegetation. Part of the restaurant is walk-terrace. The cottages are designed masonry with contact insulating system. Partitions are designed as plasterboard. Roofs are designed as counter recognized truss. The thesis contains drawings and technical documentation and it is composed as an implementation project.

The subject of my thesis is the design of new mountain hotel based on wood, which is located at the top of Little Maple, cadastral area Trinec-Tyra, the city of Trinec, Frydek-Mistek level documentation for construction. The building has a partial basement, with three floors. The supporting system consists of three structural systems. The structural system consists of basement formwork, the first floor is made of ceramic blocks heluz, second and third floor is designed as a timber frame panel. Roof structure is made up of lattice wood trusses and gabled aisle. Proposal mountain hotel respects the territorial plan of Trinec. Furthermore, emphasis is placed on the layout, including ensuring the design to the static, architectural, energy savings and safety in the use of the building.

A rutina é empregada como antioxidante e na prevenção da fragilidade capilar. Pode ser veiculada em emulsões tópicas adequadas para atingir o local de ação. Estudos de penetração in vitro através da pele humana seria a situação ideal, entretanto, há dificuldades de sua obtenção e manutenção de sua viabilidade. Entre os demais modelos de membrana, a muda de pele de cobra apresenta-se como estrato córneo puro, fornecendo barreira similar ao humano e é obtida sem a morte do animal. Os objetivos desta pesquisa foram: (1) desenvolver e avaliar a estabilidade de emulsões cosméticas, contendo rutina e promotores de penetração cutânea, tais como, uréia (U), isopropanol (IP) e propilenoglicol (PG); (2) avaliar a liberação da referida substância ativa das emulsões e; (3) avaliar a penetração e a retenção cutânea in vitro da rutina da formulação de melhor desempenho. Emulsões foram desenvolvidas com rutina a 5,0% p/p e U, IP e PG, associados ou não e em proporções distintas, segundo planejamento fatorial com dois níveis com ponto central. Quantificou-se a rutina das emulsões por espectrofotometria a 361,0 nm, método previamente validado. A liberação da rutina nas formulações foi realizada em células de difusão vertical com membrana de acetato de celulose e água destilada e álcool etílico absoluto 99,5% (1:1), como fluido receptor. O experimento foi conduzido em um período de seis horas, a 37,0 ±. 0,5 °C e agitação constante de 300 rpm.>f. emulsão de melhor desempenho quanto à liberação foi estudada quanto à estabilidade (Testes de Estabilidade Acelerada). Para o estudo de penetração e retenção cutânea da rutina dessa formulação foi utilizada muda de pele de cobra de Crotalus durissus. Empregou-se o método espectrofotométrico validado a 410,0 nm para a quantificação da rutina após liberação, penetração e retenção cutânea. Todas as emulsões foram consideradas adequadas após desenvolvimento das formulações. A uréia (isolada e em associação com IP e PG) e o isopropanol (isolado e em associação com PG) influenciaram negativamente a liberação da rutina das emulsões em diversos parâmetros. A rutina liberada e acumulada da formulação contendo PG a 5,0% p/p possuiu valor de 648,80 ±. 53,01 &#181g/cm2. Fora do esperado, a preparação contendo o número maior de promotores (U 5,0% p/p, IP 5,0% p/p e PG 5,0% p/p) resultou em liberação de menor magnitude igual a 419,76 ±. 17,98 &#181g/cm2. A presença do PG apresentou-se mais eficiente na liberação da rutina, mas não na sua penetração através da muda de pele de C. durissus, retendo 0,931 ± 0,0391 µg de rutina/mg de muda de pele de cobra. Nas condições de armazenamento a 25,0 ±2,0 °C; 5,0 ±0,5 °C e 45,0 ±. 0,5 °C, a emulsão com PG e rutina apresentou-se quimicamente estável durante 30 dias. De acordo com os resultados, a emulsão contendo PG apresentou liberação mais expressiva da rutina, no entanto, não ocorreu a penetração cutânea, mas apenas sua retenção no estrato córneo de C. durissus. A preparação manteve-se estável em todas as condições de armazenamento. / Rutin is employed as antioxidant and to prevent the capillary fragility and, when incorporated in cosmetic emulsions, it must target the action site. In vitro cutaneous penetration studies through human skin is the ideal situation, however, there are difficulties to obtain and to maintain this tissue viability. Among the membrane models, the shed snake skin presents itself as pure stratum corneum, providing barrier function similar to human and it is obtained without the animal sacrifica. The objectives of this research were: (1) development and stability evaluation of cosmetic emulsions containing rutin and penetration enhancers, as urea (U), isopropanol (IP) and propylene glycol (PG); (2) release evaluation of the mentioned active substance from the emulsions and; (3) evaluation of rutin in vitro cutaneous penetration and retention from the emulsion of the best performance. Emulsions were developed with rutin 5.0% w/wand U, IP and PG, associated or not according to factorial design with two levels and central point. Active substance on the formulations was quantified by a validated spectrophotometric method at 361.0 nm. Rutin release from emulsions was performed in vertical diffusion cells with cellulose acetate membrane and distilled water and ethanol 99.5% (1:1), as receptor fluid. The experiment was conducted for six hours, at 37.0 ± 0.5 °c with constant stirring of 300 rpm. Formulation with best profile of rutin release had its stability studied by the Accelerated Stability Assays. Rutin cutaneous penetration and retention from the mentioned emulsion was performed with shed snake skin from Crotalus durissus. Spectrophotometry at 410.0 nm, previously validated, determined the active substance after release and cutaneous penetration/retention. Ali emulsions were considered apparently stables after development. Urea (isolated and associated with IP and PG) and isopropanol (isolated and associated with PG) have influenced negatively the rutin release in several parameters. Emulsion with PG 5.0% w/w presented rutin released and accumulated equal to 648.80 ± 53.01 µg/cm2. Unexpectedly, the formulation containing all enhancers (U 5.0% w/w, IP 5.0% w/w and PG 5.0% w/w) has decreased the amount released of the active substance (419.76 ± 17.98 µg/cm2). Emulsion with PG presented more adequate for rutin release, but PG did not provide rutin cutaneous penetration through C. durissus skin, retaining 0.931 ± 0.0391 &$181;g rutin/mg shed snake skin. The referred formulation was chemically stable for 30 days after they have been stored at 25.0 ± 2.0 °c, 5.0 ± 0.5 °c and 45.0 ± 0.5 °C. In conclusion, emulsion with PG provided rutin release more expressively, although, it has not been verified the active cutaneous penetration, but only its retention on the Crotalus durissus stratum corneum. Formulation was stable in all storage conditions.

This practicum is a reference for vertical gardeners in cold climates. Winnipeg, Manitoba is explored, however findings may be applied to other cities in similar climates. First, the history of vertical gardening is discussed, then the types of vertical gardens currently on the market are described. These can be classified into two categories: soil bearing or non-soil bearing. Most designs are modular pre-planted systems that can be attached to any wall, as long as it satisfies the structural requirements recommended by the manufacturer. The benefits of vertical gardening have been shown to be rather extensive, covering a wide range of areas. Aesthetic improvement, reduction of the Urban Heat Island (UHI) effect, improvement of air quality, stormwater absorption, noise reduction, native habitat integration, reduction of heating and cooling costs for buildings, food production, marketing, and biophilia are all benefits explored in detail. Difficulties associated with vertical gardening are discussed, specifically the lack of knowledge and awareness of vertical gardens, lack of empirical evidence (or missing details in existing research), overall cost and lack of financial incentives, lack of industry codes, and various associated risks. Design framework exists within microclimate conditions unique to vertical gardens, as well as neighbourhood and regional (micro)climates. Theories relating to the study of green walls covered include the human ecosystem model, urban reconciliation ecology, habitat templating, the urban cliff hypothesis, and wall ecology. Suitable habitat templates identified for vertical gardens in Winnipeg are cliffs, sand dunes, alvars, mixed grass prairie and prairie potholes. Design parameters to be followed for vertical garden design in Winnipeg are to ensure that lightweight materials are used, to provide insulation to protect plants from sudden temperature changes, to choose plants that grow in the region and are adapted to grow in areas with limited soil, increased wind, varying degrees of sunlight (depending on orientation), and increased pollution and salt spray depending on location. / October 2015