<p>Den vård som har starkast evidens vid behandling av tvångssyndrom, Obsessive Compulsive Disorder (OCD), är kognitiv beteendeterapi (KBT), innehållande exponering och responsprevention. Idag är tillgången till denna vård begränsad främst på grund av för få behandlare. Tidigare forskning pekar på att personer med OCD kan bli hjälpta av mindre terapeutintensiva behandlingar. Att leverera vård stegvis med ökande behandlingsintensitet; Stepped Care, kan vara ett sätt att öka tillgängligheten av KBT. Denna pilotstudie har undersökt Stepped Care för OCD i form av tre steg, på Ångestenheten, Karolinska Universitetssjukhuset. Det primära syftet har varit att bidra till kunskapsinsamlingen kring Stepped Care vid OCD. Sammanlagt 19 vuxna patienter ingår i pilotstudien. 8 blev förbättrade efter självhjälp, 5 efter gruppbehandling, 2 efter individualterapi samt 4 bortfall. Av dessa behöll 7 av självhjälps-, 3 av grupp- och ingen av individualpatienterna sina framsteg vid en uppföljning 12 veckor efter avslutad behandling. Totalt tog behandlingen 244 terapeuttimmar i anspråk, vilket är mer än en halvering mot traditionell individualbehandling. Resultaten tyder på att Stepped Care är ett intressant alternativ för att effektivisera och öka tillgängligheten av vård för OCD-patienter.</p>

Den vård som har starkast evidens vid behandling av tvångssyndrom, Obsessive Compulsive Disorder (OCD), är kognitiv beteendeterapi (KBT), innehållande exponering och responsprevention. Idag är tillgången till denna vård begränsad främst på grund av för få behandlare. Tidigare forskning pekar på att personer med OCD kan bli hjälpta av mindre terapeutintensiva behandlingar. Att leverera vård stegvis med ökande behandlingsintensitet; Stepped Care, kan vara ett sätt att öka tillgängligheten av KBT. Denna pilotstudie har undersökt Stepped Care för OCD i form av tre steg, på Ångestenheten, Karolinska Universitetssjukhuset. Det primära syftet har varit att bidra till kunskapsinsamlingen kring Stepped Care vid OCD. Sammanlagt 19 vuxna patienter ingår i pilotstudien. 8 blev förbättrade efter självhjälp, 5 efter gruppbehandling, 2 efter individualterapi samt 4 bortfall. Av dessa behöll 7 av självhjälps-, 3 av grupp- och ingen av individualpatienterna sina framsteg vid en uppföljning 12 veckor efter avslutad behandling. Totalt tog behandlingen 244 terapeuttimmar i anspråk, vilket är mer än en halvering mot traditionell individualbehandling. Resultaten tyder på att Stepped Care är ett intressant alternativ för att effektivisera och öka tillgängligheten av vård för OCD-patienter.

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Sleep is essential for survival but a significant minority of the adult population are dissatisfied with their sleep, and 6-10% meet the criteria for insomnia disorder, characterised by difficulties falling asleep at bedtime, waking up in the middle of the night or too early in the morning, and daytime symptoms. Cognitive behavioural therapy for insomnia (CBT-I), an evidence-based sleep-focused intervention, has been suggested as the treatment of choice for chronic insomnia. However, access to specialised sleep therapists is sparse, and a service delivery model based on the principles of ‘stepped care’ has been proposed. Even though CBT-I is shown to be effective, there is a need to continue the development of cognitive behavioural treatments for insomnia. As a complement to traditional interventions, the potential value of acceptance, that is, to make an active choice of openness towards psychological experiences, has been recognized. However, it has not yet been systematically investigated, and specific instruments for studying acceptance in insomnia are lacking. The present thesis is based on three studies: Study I showed that manual-guided CBT for insomnia delivered by ordinary primary care personnel has a significant effect on perceived insomnia severity, sleep onset latency and wake time after sleep onset. Study II demonstrated that non-responders in Study I reported shorter sleep time at baseline than did responders, a notion that may help select patients for this type of low-end intervention in a stepped care treatment approach. Study III aimed to develop a new assessment instrument for studying acceptance of insomnia, the Sleep Problem Acceptance Questionnaire (SPAQ), resulting in an eight-item questionnaire with two factors; the first being Activity Engagement, persisting with normal activities even when sleep is unsatisfactory, and the second involving Willingness, avoiding fighting and trying to control sleep problems. In conclusion, the present thesis demonstrates that it is feasible to treat patients with insomnia using CBT-I administrated by ordinary primary care personnel in general practice, and that those with relatively longer initial sleep duration benefit most from treatment, enabling allocation to relevant treatment intensity. In addition, acceptance of sleep difficulties may be quantified using the SPAQ.

Postpartum Depression (PPD) occurs in 10-20% of new mothers. PPD can lead to serious health risks to both the mother and infant, increase the risk of complications during birth, and cause lasting effects on the development and wellbeing of the child. Many mothers suffering from PPD do not receive treatment due to fear of being stigmatized, lack of education, or not being able to access mental health services. High prevalence of PPD, along with the negative and lasting effects it can cause point to the importance of developing an effective and feasible method of assessing and treating this disorder. A pediatric primary care office may be an opportune setting to screen for PPD since mothers often accompany their children to regularly scheduled well child visits. While some studies have examined PPD screening within the pediatric primary care setting, few have explored the addition of an on-site Behavioral Health Consultant to provide brief interventions for depressed mothers as part of a stepped care model. The primary aim of the current study is assess the feasibility of implementing a stepped care protocol that assesses PPD and provides brief interventions and referrals for depressed mothers within a pediatric primary care clinic. The protocol consists of several phases including: 1) distribution of the Edinburgh Postpartum Depression Screener to every mother arriving for a well child visit during the first six months of their child’s life; 2) appropriate documentation in the clinic’s electronic health record (EHR) of the Edinburgh score and resulting plan of action; 3) a brief same day intervention by the on-site Behavioral Health Consultant and referral to outside provider, if applicable; and 4) phone call follow up with the mother and referred provider, if applicable. Research assistants will monitor the EHR to determine the clinic’s fidelity to the protocol (e.g., if the Edinburgh is being administered properly). Data will also be collected from the EHR to determine if a correlation exists between Edinburgh scores and number of Emergency Room visits made by the child, immunizations administered to the child, and number of well child checks the child attended. Data collected throughout the month of March showing the Edinburgh uptake, consistency with protocol, and any correlation between Edinburgh scores and other variables will be presented.

<p>Egentlig depression är en folksjukdom, men i dagsläget är kognitiv beteendeterapi, som fått mest stöd i depressionsforskning, en bristvara. Därav finns ett behov av att med begränsade resurser kunna hjälpa så många patienter som möjligt och då är Internetbaserad självhjälpsbehandling i ett alternativ vid mild till måttlig depression. Denna behandlingsform kan dock inte hjälpa alla, varför de som inte svarat på den inledande behandlingen som ett andra steg bör erbjudas mer intensiv och individualiserad vård; så kallad. stepped care. Vid depression uppvisar vissa patienter sudden gains, det vill säga relativt stora, snabba och stabila minskningar av symptom, som ofta bibehålls på lång sikt.</p><p>Syftet med studien var att undersöka effekten av stepped care vid mild till måttlig depression, vinna ökade kunskaper om sudden gains samt se om överlappningar mellan sudden gains och stepped care fanns.</p><p>85 deltagare inkluderades i studien, varav 69 randomiserades till Internetbaserad självhjälpsbehandling eller live gruppbehandling. Övriga deltagare utgjorde en preferensgrupp där de själva valt Internetbehandling. Båda behandlingsalternativen utgick från samma KBT-baserade behandlingsmoduler, som administrerades under åtta veckor samtidigt som veckovisa självskattningar med MADRS-S hämtades in. Efter avslutad behandling bedömdes vilka deltagare, bland dem som fått Internetbehandling, som var i behov av fortsatt vård och därmed skulle erbjudas ytterligare åtta sessioner med telefonterapi.</p><p>Efter de första åtta veckorna var 70 % av samtliga deltagare utan diagnos och 40 % av deltagarna hade uppvisat sudden gains. Endast 22 % visade sig vid eftermätningen behöva gå vidare till telefonterapi, varav 60 % tackade ja och 40 % fullföljde. Efter avslutad telefonterapi var 75 % av dessa deltagare utan diagnos. En begränsning med studien är att den endast är partiellt randomiserad. Slutsatsen är att den Internetbaserade självhjälpsbehandlingen var så effektiv att få deltagare behövde ytterligare vård i stepped care. De deltagare som uppvisade sudden gains mådde bättre än övriga vid behandlingens slut och fortsatte att må bättre vid enmånadsuppföljning.</p>

Egentlig depression är en folksjukdom, men i dagsläget är kognitiv beteendeterapi, som fått mest stöd i depressionsforskning, en bristvara. Därav finns ett behov av att med begränsade resurser kunna hjälpa så många patienter som möjligt och då är Internetbaserad självhjälpsbehandling i ett alternativ vid mild till måttlig depression. Denna behandlingsform kan dock inte hjälpa alla, varför de som inte svarat på den inledande behandlingen som ett andra steg bör erbjudas mer intensiv och individualiserad vård; så kallad. stepped care. Vid depression uppvisar vissa patienter sudden gains, det vill säga relativt stora, snabba och stabila minskningar av symptom, som ofta bibehålls på lång sikt. Syftet med studien var att undersöka effekten av stepped care vid mild till måttlig depression, vinna ökade kunskaper om sudden gains samt se om överlappningar mellan sudden gains och stepped care fanns. 85 deltagare inkluderades i studien, varav 69 randomiserades till Internetbaserad självhjälpsbehandling eller live gruppbehandling. Övriga deltagare utgjorde en preferensgrupp där de själva valt Internetbehandling. Båda behandlingsalternativen utgick från samma KBT-baserade behandlingsmoduler, som administrerades under åtta veckor samtidigt som veckovisa självskattningar med MADRS-S hämtades in. Efter avslutad behandling bedömdes vilka deltagare, bland dem som fått Internetbehandling, som var i behov av fortsatt vård och därmed skulle erbjudas ytterligare åtta sessioner med telefonterapi. Efter de första åtta veckorna var 70 % av samtliga deltagare utan diagnos och 40 % av deltagarna hade uppvisat sudden gains. Endast 22 % visade sig vid eftermätningen behöva gå vidare till telefonterapi, varav 60 % tackade ja och 40 % fullföljde. Efter avslutad telefonterapi var 75 % av dessa deltagare utan diagnos. En begränsning med studien är att den endast är partiellt randomiserad. Slutsatsen är att den Internetbaserade självhjälpsbehandlingen var så effektiv att få deltagare behövde ytterligare vård i stepped care. De deltagare som uppvisade sudden gains mådde bättre än övriga vid behandlingens slut och fortsatte att må bättre vid enmånadsuppföljning.

Stepped care is designed to provide mental health treatment in the most effective and efficient way. It aims to provide patients with low intensity interventions in the first instance and only move onto high intensity treatments if outcome is not 'successful'. However, there is a paucity of research about how health professionals make decisions about treatment and the experiences of patients within this decision-making process. Using a multi-method approach, this study aimed to explore health professional and patient decision-making in stepped care for anxiety and depression. 24 health professional interviews from three stepped care sites were conducted, which included the completion of an active information search (AIS) think-aloud task. In addition, 14 patients were interviewed about their experiences of decision-making whilst being managed within stepped care model. Qualitative interview data was analysed using the principles of Framework analysis, while some of the data collected in the AIS think-aloud task lent itself to quantitative analysis.This study revealed that three core tensions exist when making decisions within the stepped care model. These are 1. The notion of standardisation of outcomes versus the individual needs of patients; 2. The public health orientation of stepped care versus the therapeutic orientation of health professionals and; 3. The rhetoric about patient choices versus the realities of shared decision-making in a resource-limited system.The complexity of decision-making within the stepped care model was highlighted. The success of stepped care relies on ensuring that there is an adequate workforce to deliver the intended interventions, where this is not present health professionals are faced with difficult decisions and it is clear that those most affected are the less-experienced frontline workers. Scarcity of resources impacts heavily upon the decisions that are made. This can have a substantial impact upon variability in treatment decisions and on the ability to allow for patient choice to be incorporated. Decisions that are made for a patient are influenced by the need to provide them with the treatment that they want (which may not be regarded as what they need within the stepped care model nor necessarily by the health professional) and the capacity of the service. The problem that exists with primary care mental health is that the current demands exceed capacity. Optimal patient care is, in part, traded off by the need to meet the demands of the service. Improving the flexibility of the service may be one solution to the problem and adopting a stratified/stepped care approach might help to resolve some of the tensions and help to relieve some of the capacity issues.

Introduction: Research has shown that Postpartum Depression (PPD) occurs in 10-20% of new mothers. Symptoms of PPD include excessive sadness, increased anxiety, guilt, and possible suicidal ideation. PPD can increase a mother’s risk for health and psychological dysfunction including future psychiatric illnesses, substance abuse, and decrease her adaptive functioning. PDD can also have negative implications on child safety practices and a child’s psychosocial and developmental wellbeing. Treatments for PPD, such as medication and psychotherapy, have been shown to be effective at reducing the number and severity of a mother’s symptoms, and generally improving their lives and the lives of their families. Unfortunately, many mothers do not receive treatment due to fears of stigma, inadequate screening practices and an inability to access care. Thus, early detection and improved access to care is critical and literature suggests formal screening practices increases the rate of detection. Pediatrician’s offices serve as ideal locations to screen mothers and connect them to appropriate services because of frequent contact with the mother. Methods: Recognizing this public health concern, the American Academy of Pediatrics developed PPD screening guidelines. ETSU Pediatrics, a local pediatric primary care clinic, adhered to these guidelines, assembled an interdisciplinary health care team, and developed a stepped care protocol to not only screen all new mothers but connect them with immediate, onsite behavioral health services. The protocol consisted of four distinct phases: 1) distribution of the Edinburgh Postnatal Depression Scale (EPDS), an evidence- based tool screening for depression in new mothers, to every mother of infants 0 to 6 months at their well- child visit; 2) appropriate documentation of the EPDS score and plan of action noted within the electronic medical record (EHR); 3) brief behavioral health intervention conducted by the on-site behavioral health consultant, and/or referral to outside provider; 4) phone call follow up with mother and referred provider. The aim of the study is to evaluate components of intervention feasibility based upon the RE-AIM framework (Reach, Effectiveness, Adoption, Implementation, and Maintenance), which stems from the Dissemination and Implementation Science field. This particular project extends past previous pilot studies to include EHR chart review from an entire year and evaluates the protocol’s feasibility by examining Adoption and Maintenance domains. Results: Results were collected from EHR and billing records of all patients, 0 to 6 months of age, seen at the clinic from February 26, 2014 to February 25, 2015 (n = 755) for their well-child visit (n = 2,459). Adoption will examine feasibility by noting the percentage of mothers who were administered the EPDS as well as the general trend in administration across the year. Maintenance will examine feasibility from a financial perspective and reveal the amount of reimbursement accrued by billing for the EPDS. Conclusions: The anticipated results will have implications on the