In this thesis we present cloud-scale ALMA observations of two local mergers, NGC 3256 and NGC 4038/9 (the "Antennae"), in CO J=2-1. Through a pixel-based analysis of NGC 3256 we measure molecular-gas properties and compare to nearby spiral galaxies from the PHANGS-ALMA survey. NGC 3256 exhibits high mass surface densities, velocity dispersions, peak brightness temperatures, virial parameters, and internal turbulent pressures. High surface densities are expected to accompany its high star-formation rate, and high brightness temperatures may indicate warmer gas, heated by the vigorous star formation. Large virial parameters and internal pressures imply the molecular gas is not bound by self-gravity, but we explore how material external to clouds could alter this. We argue the molecular gas in NGC 3256 is smoother than in nearby spiral galaxies down to 55 pc. We also perform a cloud analysis of our NGC 3256 observations, identifying 185 clouds, and find similar results to the pixel analysis. We calculate additional cloud properties including eccentricity, CO luminosity, CO-estimated mass, virial mass, size-linewidth coefficient, and free-fall time. Properties in NGC 3256 are extreme compared to clouds from PHANGS-ALMA, including slightly larger clouds and shorter free-fall times. Cloud eccentricities in NGC 3256 are similar to those in PHANGS-ALMA galaxies, possibly indicating similar average cloud dynamical states. The shape of the cloud mass function in NGC 3256 is similar to many PHANGS-ALMA galaxies. Finally, we analyse our NGC 4038/9 observations using the same pixel methods as used in NGC 3256. NGC 4038/9 also harbours extreme molecular-gas properties and potentially smoother emission compared to spiral galaxies, but not as extreme as NGC 3256. We find the most-massive spiral galaxies have central molecular-gas properties similar to the mergers. Virial parameters in NGC 4038/9 are similar to many spiral galaxies, making it quite different from NGC 3256, potentially due to their different merger stages. Comparison of the overlap region of NGC 4038/9 in CO (2-1) to CO (3-2) shows general agreement. / Thesis / Doctor of Philosophy (PhD)