Global ETD Search

41	Possible Role of Osteoblasts in Regulating the Initiation of Endochondral Repair Process during Fracture Healing Amani Andabili, Yasha 21 March 2012 (has links) Fracture repair is a regenerative event that involves the precise coordination of a variety of cells for successful healing process. Within the microstructure hierarchy of bone repair, the predominant cells involved include the chondrocytes, osteocytes, osteoblasts, and osteoclasts. Although the role of osteoblasts during fracture healing has been previously shown, their role during the initiation phase of endochondral fracture repair remains unclear. In order to study the role of osteoblasts during fracture repair, we used a transgenic mouse model expressing the herpes simplex virus thymidine kinase gene in early differentiating osteoblasts, which allows conditional ablation of cells in osteoblastic lineage upon treatment with the Gancicolvir drug. Results from this study suggest that not only are osteoblasts required in later stages of fracture repair as the medium for bone synthesis, and osteoclast activation during bone remodelling, but could also be required for the initiation and advancement of the endochondral ossification process. Fracture repair Endochondral Ossification Osteoblast Osteoclast Chondrocyte Herpes simplex virus thymidine kinase Gacnciclovir
42	グリオーマの遺伝子治療若林, 俊彦, 中原, 紀元, 水野, 正明, 梶田, 泰一, 吉田, 純, Wakabayashi, Toshihiko, Nakahara, Norimoto, Kajita, Yasukazu, Mizuno, Masaaki, Yoshida, Jun 08 1900 (has links) No description available. glioma gene therapy clinical trial cytokine
43	Characterization of transport of positron emission tomography tracer 3'-deoxy-3'-fluorothymidine by nucleoside transporters Paproski, Robert Joseph. January 2010 (has links) Thesis (Ph.D.)--University of Alberta, 2009. / A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Doctor of Philosophy, Oncology. Title from pdf file main screen (viewed on January 30, 2010). Includes bibliographical references.
44	Die Bedeutung der Thymidinphosphorylase bei Patienten mit lokal fortgeschrittenem Rektumkarzinom (UICC-Stadium-II/-III) im Kontext einer 5-FU basierten multimodalen Therapie / The significance thymidine phosphorylase has on patients with locally advanced rectal cancer (UICC-Stadium-II/-III) with regard to a 5-FU based multimodal therapy Specking, Matthias 23 June 2014 (has links) No description available. 610 Thymidinphosphorylase Rektumkarzinom 5-Fluorouracil Thymidine phosphorylase 5-Fluorouracil rectal cancer
45	Suicide gene therapy using adenovirus vector for human oral squamous carcinoma cell line In vitro Yamamoto, Noriyuki, Hayashi, Yasushi, Kagami, Hideaki, Fukui, Takafumi, Fukuhara, Hirokazu, Tohnai, Iwai, Ueda, Minoru, Mizuno, Masaaki, Yoshida, Jun 06 1900 (has links) No description available. Squamous Cell Carcinoma Adenovirus Ganciclovir Bystander effect
46	Bacterial enzymes in thymidylate synthesis : molecular characterization of thymidine kinase and thymidylate kinase in Ureaplasma urealyticum and Bacillus anthracis; implications for antibacterial therapy / Carnrot, Cecilia, January 2006 (has links) (PDF) Diss. (sammanfattning) Uppsala : Sveriges lantbruksuniversitet, 2006. / Härtill 5 uppsatser.
47	Caractérisation des mutations du virus Herpès simplex impliquées dans la résistance aux antiviraux Bestman-Smith, Julie. January 1900 (has links) (PDF) Thèse (Ph.D.)--Université Laval, 2004. / Titre de l'écran-titre (visionné le 29 novembre 2004). Bibliogr.
48	An evaluation of the vaccine-vector potential of thymidine kinase-disrupted recombinants of lumpy skin disease virus (South African vaccine) Wallace, David Brian 06 September 2006 (has links) Please read the abstract in the section 00front of this document / Thesis (PhD (Genetics))--University of Pretoria, 2007. / Genetics / unrestricted Vaccine vector Capripoxvirus Lumpy skin disease Poxvirus Thymidine kinase Lacz UCTD
49	X-Ray Crystallographic Studies On Tosyl, Trityl Nucleosides And A 2'-Nucleotide Prahadeeswaran, D 05 1900 (has links) (PDF) No description available. Nucleotides X-ray Crystallography Tosyl Adenosine Trityl Uridine Trityl Thymidine Biophysics
50	Enhancing the sensitivity of the thymidine kinase assay by using DNA repair-deficient human TK6 cells / DNA修復欠損TK6細胞を使った化学物質のDNA毒性の向上を目指した実験評価系の開発 Mahmoud, Abdelghany Ibrahim 23 September 2020 (has links) 京都大学 / 0048 / 新制・課程博士 / 博士(医学) / 甲第22723号 / 医博第4641号 / 新制\|\|医\|\|1045(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授篠原隆司, 教授溝脇尚志, 教授増永慎一郎 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM DNA-damaging agent OECD guideline thymidine kinase assay TK assay TK6 cells 490

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