This thesis investigates the feasibility of using the non-invasive biomedical signal of oxygen saturation, or SpO₂ , to diagnose a sleep disorder known as Obstructive Sleep Apnoea Hypopnoea Syndrome (OSAHS). Epidemiologically, OSAHS is the most common condition investigated by sleep clinics. In a patient suspected of having the disorder, the upper airway is obstructed during sleep and a cessation in respiration results. An apnoea is defined as a temporary cessation of breathing. Similarly, a hypopnoea is defined as any reduction in breathing (i.e., less severe than an apnoea). The work has three main objectives; the first being to establish automated evaluation procedures for methods of quantifying apnoeic activity from the SpO₂ signal, the second being to accurately identify apnoeic and normal activity on a minute-by-minute basis, the third being to create a Respiratory Disturbance Index (RDI) based on the analysis which is comparable to the gold-standard Apnoea Hypopnoea Index (AHI) derived by experts. The detection of apnoeic activity is determined using three separate analyses: time domain, frequency domain, and autoregressive modelling with an incorporated amplitude criterion. A training dataset is utilised for algorithm development, and an independent dataset is employed for testing . All three methods result in comparable overall classification accuracies of: 81.2% (time domain), 82.1% (frequency domain), and 80.0% (autoregressive modelling with amplitude). In addition, particular attention is given to the resultant sensitivity, specificity, and accuracy values partitioned according to patient category; i.e., patients with OSAHS may be divided into normal, mild, moderate and severe. Lastly, a simple RDI is computed based on the automated analyses; i.e., the number of apnoeic segments detected divided by the total number of segments used. A comparison between computed RDI and AHI values for the test database show correlation values above 0.8. In conclusion, this thesis shows that through the automated analysis of the SpO₂ signal, OSAHS severity in patients suspected of having the disorder can be quantified. The AR-modelling with an incorporated amplitude criterion, in particular, shows the most promise for further work in this area.

Abstract The quantitation of the variability in cardiovascular signals provides information about the autonomic neural regulation of the heart and the circulatory system. Several factors have an indirect effect on these signals as well as artifacts and several types of noise are contained in the recorded signal. The dynamics of RR and QT interval time series have also been analyzed in order to predict a risk of adverse cardiac events and to diagnose them. An ambulatory measurement setting is an important and demanding condition for the recording and analysis of these signals. Sophisticated and robust signal analysis schemes are thus increasingly needed. In this thesis, essential points related to ambulatory data acquisition and analysis of cardiovascular signals are discussed including the accuracy and reproducibility of the variability measurement. The origin of artifacts in RR interval time series is discussed, and consequently their effects and possible correction procedures are concidered. The time series including intervals differing from a normal sinus rhythm which sometimes carry important information, but may not be as such suitable for an analysis performed by all approaches. A significant variation in the results in either intra- or intersubject analysis is unavoidable and should be kept in mind when interpreting the results. In addition to heart rate variability (HRV) measurement using RR intervals, the dy- namics of ventricular repolarization duration (VRD) is considered using the invasively obtained action potential duration (APD) and different estimates for a QT interval taken from a surface electrocardiogram (ECG). Estimating the low quantity of the VRD vari- ability involves obviously potential errors and more strict requirements. In this study, the accuracy of VRD measurement was improved by a better time resolution obtained through interpolating the ECG. Furthermore, RTmax interval was chosen as the best QT interval estimate using simulated noise tests. A computer program was developed for the time interval measurement from ambulatory ECGs. This thesis reviews the most commonly used analysis methods for cardiovascular vari- ability signals including time and frequency domain approaches. The estimation of the power spectrum is presented on the approach using an autoregressive model (AR) of time series, and a method for estimating the powers and the spectra of components is also presented. Time-frequency and time-variant spectral analysis schemes with applica- tions to HRV analysis are presented. As a novel approach, wavelet and wavelet packet transforms and the theory of signal denoising with several principles for the threshold selection is examined. The wavelet packet based noise removal approach made use of an optimized signal decomposition scheme called best tree structure. Wavelet and wavelet packet transforms are further used to test their effciency in removing simulated noise from the ECG. The power spectrum analysis is examined by means of wavelet transforms, which are then applied to estimate the nonstationary RR interval variability. Chaotic modelling is discussed with important questions related to HRV analysis.ciency in removing simulated noise from the ECG. The power spectrum analysis is examined by means of wavelet transforms, which are then applied to estimate the nonstationary RR interval variability. Chaotic modelling is discussed with important questions related to HRV analysis.

No description available.

Atualmente, a exigência da indústria na construção de estruturas complexas é consequência da acirrada concorrência, principalmente, entre empresas dos segmentos rodoviários. Com o auxílio de ferramentas computacionais, baseadas no Método de Elementos Finitos, é possível dimensionar essas estruturas submetidas a solicitações aleatórias variando no tempo. Nesse caso, é comum a realização de simulações dinâmicas no domínio do tempo que se empregue um modelo de Elementos Finitos de placa ou viga e, assim, obter as tensões nos locais críticos de interesse. Porém, análises no domínio do tempo capturam tensões e deformações com boa precisão, mas costumam ser caras computacionalmente. Na maioria dos casos estudados, a vida em fadiga é fundamental para prever falhas estruturais de elevadas proporções, como o colapso da viga principal da estrutura chassi de um implemento rodoviário. Diante disso, são de interesse tecnológico e industrial as análises no domínio da frequência, a fim de diminuir o custo computacional de simulação dinâmica independente do modelo de Elementos Finitos. Com esse propósito, o presente trabalho propõe uma comparação entre metodologias capazes em estimar a vida em fadiga no domínio do tempo e da frequência, de um caso simples e um segundo caso, mais complexo, que é o da indústria. Os diferentes modelos de Elementos Finitos e métodos de cálculos da vida em fadiga no domínio da frequência são comparados e discutidos, usando-se como referência o método clássico de cálculo da vida em fadiga, domínio do tempo. A metodologia leva em conta os diferentes Elementos Finitos empregados, as simplificações dos modelos estruturais usados e potenciais restrições cinemáticas aplicadas ao modelo. A comparação é feita com a ajuda de ferramentas comerciais que executam as análises modais, harmônicas, transientes, espectrais e rotinas de cálculos. Assim, o analista pode selecionar malhas com quantidade viável de graus de liberdade tornando possível as simulações dinâmicas e, além disso, prever a vida em fadiga no domínio do tempo para modelos simples e complexos. A partir dos resultados, verificou-se que as análises de estimativa da vida em fadiga no domínio da frequência, para modelos complexos, ainda não apresentam resultados confiáveis e, assim, são sugeridas recomendações. / Currently, the industry demand for the construction of complex structures is a consequence of the fierce competition, mainly between companies from semi-trailers segments. With the support of computational tools, based on the Finite Element Method, it is possible to size these structures submitted to random requests varying in time. In this case, it is common to perform dynamic simulations in the time domain to use a Finite Element model of plate or beam and thus obtain the stresses at the critical sites of interest. However, time domain analyses capture tensions and deformations with good accuracy, but they are often computationally expensive. In most of the studied cases, fatigue life is fundamental to predict structural failures of high proportions, such as main beam collapse of the chassis structure of a semi-trailer. Therefore, the semi-trailer industry segments is interested in the frequency domain, in order to reduce the computational cost of dynamic simulation no matter of the Finite Element model. With this purpose, the present work proposes a comparison between methodologies which are able to estimate the fatigue life in time domain and frequency, of a simple and second case, more complex, that of the industry. The different Finite Element models and methods of calculating fatigue life in frequency domain are compared and discussed using the classic time domain fatigue life calculation method as reference. The methodology takes into account the different Finite Elements are used, the simplifications of the structural models used and potential kinematic constraints applied to the model. The comparison is made with not only the following analyses: modal, harmonic, transient, spectral, but also computational routines. Thus, the analyst can select meshes with a viable amount of degrees of freedom making dynamic simulations possible, in addition, to its predict the fatigue life in time domain for simple and complex models. Based on the results, it was verified that the fatigue life estimates in frequency domain, for complex models, do not present reliable results yet. Therefore, recommendations are suggested.

Atualmente, a exigência da indústria na construção de estruturas complexas é consequência da acirrada concorrência, principalmente, entre empresas dos segmentos rodoviários. Com o auxílio de ferramentas computacionais, baseadas no Método de Elementos Finitos, é possível dimensionar essas estruturas submetidas a solicitações aleatórias variando no tempo. Nesse caso, é comum a realização de simulações dinâmicas no domínio do tempo que se empregue um modelo de Elementos Finitos de placa ou viga e, assim, obter as tensões nos locais críticos de interesse. Porém, análises no domínio do tempo capturam tensões e deformações com boa precisão, mas costumam ser caras computacionalmente. Na maioria dos casos estudados, a vida em fadiga é fundamental para prever falhas estruturais de elevadas proporções, como o colapso da viga principal da estrutura chassi de um implemento rodoviário. Diante disso, são de interesse tecnológico e industrial as análises no domínio da frequência, a fim de diminuir o custo computacional de simulação dinâmica independente do modelo de Elementos Finitos. Com esse propósito, o presente trabalho propõe uma comparação entre metodologias capazes em estimar a vida em fadiga no domínio do tempo e da frequência, de um caso simples e um segundo caso, mais complexo, que é o da indústria. Os diferentes modelos de Elementos Finitos e métodos de cálculos da vida em fadiga no domínio da frequência são comparados e discutidos, usando-se como referência o método clássico de cálculo da vida em fadiga, domínio do tempo. A metodologia leva em conta os diferentes Elementos Finitos empregados, as simplificações dos modelos estruturais usados e potenciais restrições cinemáticas aplicadas ao modelo. A comparação é feita com a ajuda de ferramentas comerciais que executam as análises modais, harmônicas, transientes, espectrais e rotinas de cálculos. Assim, o analista pode selecionar malhas com quantidade viável de graus de liberdade tornando possível as simulações dinâmicas e, além disso, prever a vida em fadiga no domínio do tempo para modelos simples e complexos. A partir dos resultados, verificou-se que as análises de estimativa da vida em fadiga no domínio da frequência, para modelos complexos, ainda não apresentam resultados confiáveis e, assim, são sugeridas recomendações. / Currently, the industry demand for the construction of complex structures is a consequence of the fierce competition, mainly between companies from semi-trailers segments. With the support of computational tools, based on the Finite Element Method, it is possible to size these structures submitted to random requests varying in time. In this case, it is common to perform dynamic simulations in the time domain to use a Finite Element model of plate or beam and thus obtain the stresses at the critical sites of interest. However, time domain analyses capture tensions and deformations with good accuracy, but they are often computationally expensive. In most of the studied cases, fatigue life is fundamental to predict structural failures of high proportions, such as main beam collapse of the chassis structure of a semi-trailer. Therefore, the semi-trailer industry segments is interested in the frequency domain, in order to reduce the computational cost of dynamic simulation no matter of the Finite Element model. With this purpose, the present work proposes a comparison between methodologies which are able to estimate the fatigue life in time domain and frequency, of a simple and second case, more complex, that of the industry. The different Finite Element models and methods of calculating fatigue life in frequency domain are compared and discussed using the classic time domain fatigue life calculation method as reference. The methodology takes into account the different Finite Elements are used, the simplifications of the structural models used and potential kinematic constraints applied to the model. The comparison is made with not only the following analyses: modal, harmonic, transient, spectral, but also computational routines. Thus, the analyst can select meshes with a viable amount of degrees of freedom making dynamic simulations possible, in addition, to its predict the fatigue life in time domain for simple and complex models. Based on the results, it was verified that the fatigue life estimates in frequency domain, for complex models, do not present reliable results yet. Therefore, recommendations are suggested.

Atualmente, a exigência da indústria na construção de estruturas complexas é consequência da acirrada concorrência, principalmente, entre empresas dos segmentos rodoviários. Com o auxílio de ferramentas computacionais, baseadas no Método de Elementos Finitos, é possível dimensionar essas estruturas submetidas a solicitações aleatórias variando no tempo. Nesse caso, é comum a realização de simulações dinâmicas no domínio do tempo que se empregue um modelo de Elementos Finitos de placa ou viga e, assim, obter as tensões nos locais críticos de interesse. Porém, análises no domínio do tempo capturam tensões e deformações com boa precisão, mas costumam ser caras computacionalmente. Na maioria dos casos estudados, a vida em fadiga é fundamental para prever falhas estruturais de elevadas proporções, como o colapso da viga principal da estrutura chassi de um implemento rodoviário. Diante disso, são de interesse tecnológico e industrial as análises no domínio da frequência, a fim de diminuir o custo computacional de simulação dinâmica independente do modelo de Elementos Finitos. Com esse propósito, o presente trabalho propõe uma comparação entre metodologias capazes em estimar a vida em fadiga no domínio do tempo e da frequência, de um caso simples e um segundo caso, mais complexo, que é o da indústria. Os diferentes modelos de Elementos Finitos e métodos de cálculos da vida em fadiga no domínio da frequência são comparados e discutidos, usando-se como referência o método clássico de cálculo da vida em fadiga, domínio do tempo. A metodologia leva em conta os diferentes Elementos Finitos empregados, as simplificações dos modelos estruturais usados e potenciais restrições cinemáticas aplicadas ao modelo. A comparação é feita com a ajuda de ferramentas comerciais que executam as análises modais, harmônicas, transientes, espectrais e rotinas de cálculos. Assim, o analista pode selecionar malhas com quantidade viável de graus de liberdade tornando possível as simulações dinâmicas e, além disso, prever a vida em fadiga no domínio do tempo para modelos simples e complexos. A partir dos resultados, verificou-se que as análises de estimativa da vida em fadiga no domínio da frequência, para modelos complexos, ainda não apresentam resultados confiáveis e, assim, são sugeridas recomendações. / Currently, the industry demand for the construction of complex structures is a consequence of the fierce competition, mainly between companies from semi-trailers segments. With the support of computational tools, based on the Finite Element Method, it is possible to size these structures submitted to random requests varying in time. In this case, it is common to perform dynamic simulations in the time domain to use a Finite Element model of plate or beam and thus obtain the stresses at the critical sites of interest. However, time domain analyses capture tensions and deformations with good accuracy, but they are often computationally expensive. In most of the studied cases, fatigue life is fundamental to predict structural failures of high proportions, such as main beam collapse of the chassis structure of a semi-trailer. Therefore, the semi-trailer industry segments is interested in the frequency domain, in order to reduce the computational cost of dynamic simulation no matter of the Finite Element model. With this purpose, the present work proposes a comparison between methodologies which are able to estimate the fatigue life in time domain and frequency, of a simple and second case, more complex, that of the industry. The different Finite Element models and methods of calculating fatigue life in frequency domain are compared and discussed using the classic time domain fatigue life calculation method as reference. The methodology takes into account the different Finite Elements are used, the simplifications of the structural models used and potential kinematic constraints applied to the model. The comparison is made with not only the following analyses: modal, harmonic, transient, spectral, but also computational routines. Thus, the analyst can select meshes with a viable amount of degrees of freedom making dynamic simulations possible, in addition, to its predict the fatigue life in time domain for simple and complex models. Based on the results, it was verified that the fatigue life estimates in frequency domain, for complex models, do not present reliable results yet. Therefore, recommendations are suggested.

Ces travaux de recherche portent sur la problématique CEM (Compatibilité Electromagnétique) en électronique de puissance. Cette étude s'intéresse particulièrement à la modélisation HF (haute fréquence) des convertisseurs d'énergie dans le but d'étudier la propagation des perturbations conduites vers le réseau avec ou sans l’utilisation du RSIL (Réseau Stabilisateur d'Impédance de Ligne). Une première partie présente les outils de modélisation des sources de perturbation dans les convertisseurs statiques.La seconde partie est consacrée à la modélisation HF d'un système d'entraînement à vitesse variable. L'onduleur de tension triphasé est représenté par trois générateurs équivalents afin de reconstituer le découpage des tensions de sortie. Un modèle HF du câble blindé de 4 conducteurs tenant compte de la dissymétrie est ensuite proposé. Les résultats de simulation ont été validés par des relevés expérimentaux. La comparaison montre qu'il est possible de modéliser correctement le comportement HF du dispositif jusqu'à 20MHz.Une troisième partie porte sur la propagation des perturbations conduites vers le réseau sans RSIL. Il a fallu pour cela déterminer et modéliser l'impédance du réseau. L'influence du pont redresseur à diodes sur la propagation des perturbations de mode commun a ensuite été étudiée. Les résultats de simulation montrent que l'impact de ces perturbations sur la tension réseau est prépondérant lorsque le pont redresseur est à l'état bloqué. Les résultats expérimentaux ont permis de valider cette étude. Ce travail se termine par une étude préliminaire sur l'association de deux convertisseurs connectés localement à une même source d'énergie / These research works focus on EMC (Electromagnetic Compatibility) in power electronics systems. Specifically, the study focuses on HF (high frequency) modeling of the power converters in order to study the conducted emissions toward the power grids with or without the use of an LISN (Line Impedance Stabilisation Network). The first part presents the modeling tools of the electromagnetic emissions sources in power converters.The second part describes the HF modeling method of an adjustable speed drive (ASD) that will be used to estimate the conducted emissions. In a first part, a behavioural model of PWM inverter is proposed as an EMI noise source. Then, a model of the shielded 4-wire energy cable that taking into account of the dissymmetry structure is proposed and validated in the frequency domain for two different lengths. The comparison of measurement and simulation results of conducted emissions (with LISN) shows the good compromise between the simulation duration and accuracy of the results.A third part is dedicated to the propagation of conducted emissions toward the power grid without using a LISN. The first stage consists in proposing a model impedance of the network impedance. The influence of the bridge rectifier diodes on the propagation paths of common mode disturbances has been studied in the second step. The simulation results show that the impact of these disturbances on the network voltage is more important when the bridge rectifier is normally off-state. The experimental results have validated this study. This work concludes with a preliminary study on the association of two converters connected locally to a single energy source

<p>Дисертација истражује најприхватљивије методе мерења стабилности фреквенције у<br />фреквенцијском домену, односно мерење вредности величине &bdquo;фазни шум&ldquo;, приликом<br />процеса еталонирања мерне опреме. Када се говори о мерној опреми која је предмет<br />еталонирања, дисертација је, пре свега, окренута ка еталонирању врхунских<br />комерцијалних стандарда (еталона) фреквенције. Приказана истраживања су била основ<br />за покретање и реализацију истраживачко-развојног пројекта у оквиру Министарства<br />одбране, који је имао за циљ оспособљавање метролошке лабораторије Техничког<br />опитног центра Војске Србије за потпуно еталонирање мерне опреме из области<br />времена и фреквенције. Различите методе мерења подразумевају и различите мерне<br />могућности, као и врло широк спектар еталонске и мерне опреме која се користи при<br />њиховој реализацији. У дисертацији се приказују различити начини мерења фазног шума<br />и описују методе реализоване на основу доступне мерне опреме. Како се ради о<br />методама упоредне анализе референтног и мереног сигнала, посебно критична позиција<br />је одабир референце, односно референтног еталона. Истраживање је довело до<br />закључака којима је предложен метод мерења потребне и довољне мерне несигурности<br />као и начин реализације изабране методе, односно одабир еталонске мерне опреме. У<br />циљу увођења мерне методе у употребу, извршена су и приказана мерења на<br />различитим типовима и врстама мерне опреме. Валидација методе је остварена<br />билатералним поређењем са Дирекцијом за мере и драгоцене метале, Група за време,<br />фреквенцију и дистрибуцију времена. Да је могуће реализовати методу мерења фазног<br />шума приликом еталонирања најквалитетнијих осцилатора је постављена хипотеза<br />дисертације, која је истраживањем доказана и практично спроведена. Крајњи резултат<br />истраживања је довео до увођења признате методе еталонирања фазног шума, први пут</p> / <p>Disertacija istražuje najprihvatljivije metode merenja stabilnosti frekvencije u<br />frekvencijskom domenu, odnosno merenje vrednosti veličine &bdquo;fazni šum&ldquo;, prilikom<br />procesa etaloniranja merne opreme. Kada se govori o mernoj opremi koja je predmet<br />etaloniranja, disertacija je, pre svega, okrenuta ka etaloniranju vrhunskih<br />komercijalnih standarda (etalona) frekvencije. Prikazana istraživanja su bila osnov<br />za pokretanje i realizaciju istraživačko-razvojnog projekta u okviru Ministarstva<br />odbrane, koji je imao za cilj osposobljavanje metrološke laboratorije Tehničkog<br />opitnog centra Vojske Srbije za potpuno etaloniranje merne opreme iz oblasti<br />vremena i frekvencije. Različite metode merenja podrazumevaju i različite merne<br />mogućnosti, kao i vrlo širok spektar etalonske i merne opreme koja se koristi pri<br />njihovoj realizaciji. U disertaciji se prikazuju različiti načini merenja faznog šuma<br />i opisuju metode realizovane na osnovu dostupne merne opreme. Kako se radi o<br />metodama uporedne analize referentnog i merenog signala, posebno kritična pozicija<br />je odabir reference, odnosno referentnog etalona. Istraživanje je dovelo do<br />zaključaka kojima je predložen metod merenja potrebne i dovoljne merne nesigurnosti<br />kao i način realizacije izabrane metode, odnosno odabir etalonske merne opreme. U<br />cilju uvođenja merne metode u upotrebu, izvršena su i prikazana merenja na<br />različitim tipovima i vrstama merne opreme. Validacija metode je ostvarena<br />bilateralnim poređenjem sa Direkcijom za mere i dragocene metale, Grupa za vreme,<br />frekvenciju i distribuciju vremena. Da je moguće realizovati metodu merenja faznog<br />šuma prilikom etaloniranja najkvalitetnijih oscilatora je postavljena hipoteza<br />disertacije, koja je istraživanjem dokazana i praktično sprovedena. Krajnji rezultat<br />istraživanja je doveo do uvođenja priznate metode etaloniranja faznog šuma, prvi put</p> / <p>The dissertation examines the most acceptable methods for measuring the frequency stability<br />in the frequency domain, that is, measuring the value of the &quot;phase noise&quot;, during the process<br />of measuring equipment calibration. When it comes to measuring equipment as a subject of<br />calibration, the dissertation is, first of all, oriented towards the calibration of the highest<br />commercial frequency standards. The presented researches were the basis for initiation and<br />realization of the research and development project within the Ministry of Defense, which was<br />aimed at training the metrology laboratory of the Technical Test Center of the Serbian Army<br />for complete calibration of measuring equipment in the area of time and frequency. Different<br />measurement methods also involve different measurement possibilities, as well as a very wide<br />range of calibration and measuring equipment used in their realization. Different methods of<br />measuring phase noise are described in the dissertation and they describe realized methods<br />based on available measuring equipment. As for methods of comparative analysis of the<br />reference and measured signal, a particularly critical position is the selection of the reference,<br />that is, the reference oscillator. The research led to conclusions suggesting the method of<br />measuring the necessary and sufficient measurement uncertainty, as well as the method of<br />realization of the chosen method, i.e. selection of the standard measuring equipment. In order<br />to put the measurement method into practice, measurements were performed on different<br />types of measuring equipment. Validation of the method was achieved by bilateral<br />comparison with the Directorate of Measures and Precious Metals, Group for time, frequency<br />and time dissemination. The possibility to realize the method of phase noise measurement<br />during the calibration of the highest quality oscillators is a hypothesis of the dissertation that<br />has been set up, and has been proven and practically carried out by the research. The final<br />result of the research led to the introduction of a recognized calibration method of the phase<br />noise, for the first time in the Republic of Serbia.</p>

In automatic speech recognition systems (ASRs), training is a critical phase to the system?s success. Communication media, either analog (such as analog landline phones) or digital (VoIP) distort the speaker?s speech signal often in very complex ways: linear distortion occurs in all channels, either in the magnitude or phase spectrum. Non-linear but time-invariant distortion will always appear in all real systems. In digital systems we also have network effects which will produce packet losses and delays and repeated packets. Finally, one cannot really assert what path a signal will take, and so having error or distortion in between is almost a certainty. The channel introduces an acoustical mismatch between the speaker's signal and the trained data in the ASR, which results in poor recognition performance. The approach so far, has been to try to undo the havoc produced by the channels, i.e. compensate for the channel's behavior. In this thesis, we try to characterize the effects of different transmission media and use that as an inexpensive and repeatable way to train ASR systems.