Structural and diffusion imaging patterns that can be evaluated using MRI in patients with cognitive deficits are the central theme of the proposed work. First, the clinical and neuroimaging background of dementias has been reviewed in a broader context, with a special focus on Alzheimer's disease (AD) and differential diagnoses. The second part of this thesis contains four consecutive experimental studies. The primary objective of the first two studies was to obtain structural and microstructural information on the neurodegenerative processes characteristic for AD on global and regional levels. For this purpose, several complementary approaches were used and the focus was shifted from grey to white matter (GM/WM). The following two studies focused on the differential context of WM microstructural alterations in normal pressure hydrocephalus (NPH) and distinctive patterns of WM disintegrity in temporal lobe epilepsy (TLE). The most important conclusion of our studies is that structural and diffusion imaging proved to be useful in identifying regionally specific and disproportionate loss of brain volume and microstructure in several pathological processes underlying cognitive deterioration. The use of distinctive morphometric methods yielded complementary information on AD-related atrophy patterns,...

This diploma thesis is focused on composition and processing of cellulose fibers and their usage in cementitious composites. It describes key attributes of cellulose fibers, which has to be acquired for effective use in cement composites. There are stated effects of cellulose fibers on concrete properties, such as workability, physical and mechanic attributes and freeze-thaw resistance. In experimental part is designed a mixture with portion of cellulose fibers. There has been performed various tests to define the effect of cellulose fibers. There was designed experiment to determine its alkali resistance for fibers itself, and possible changes in microstructure of fibers were analyzed by optic and electron scanning microscope.

This doctoral thesis is focused on the possibilities of alkali-activated slag (AAS) shrinkage reduction, which would together with the use of waste sludge from waterglass production contribute to wider practical utilization of this interesting material. Besides the influence on AAS dimensional changes also effect of various factors on workability, setting time and mechanical properties was investigated. Obtained results were supported by the application of instrumental techniques like izotermal calorimetry, mercury intrusion porosimetry, scanning electron microscopy and X-ray diffraction. The results show the possibilities of reduction of AAS drying shrinkage related to its cracking tendency through the combination of increased dose of waterglass and reduced water to slag ratio (w/b), partial replacement of slag by pulverized fly ash or cement by-pass dust and application of organic admixtures, where significant effect on AAS hydration was observed. On the basis of the obtained results concrete mixtures, where the whole activator was replaced by the waste sludge form waterglass production, were designed and optimized in terms of shrinkage, mechanical properties and price. Selected concretes were also tested in semi-operating conditions.

This diploma thesis is focused on building survey and evaluating the state of existing constructions. In theoretical part are described the process of evaluating the state of existing constructions and selected diagnostic methods. The practical part is dealing with performed structural and technical survey of industrial object including evaluation of the strength of concrete and verification of the reinforcement. The last part is focused on a static assessment of selected supporting element of the structure.

The works deals with the possibilities of using non-standard fraction of fine crushed aggregate in route base layers. Goal of my thesis is research of using material from specific location. Theoretical part summarizes basic knowledge regarding bound mixtures and their normative requirements. Practical part of my thesis describes my various mixture design and following testing and determination of design properties by official and experimental tests. The conclusion summarizes the researched outputs and findings, which confirm the future possibilities of using this material in base layers.

This diploma thesis is focused on methodology for sorting of solid fired bricks for reconstruction of historical buildings. The theorethical part of this thesis includes description of production technology of solid fired bricks and diagnostic methods. In practical part there are these methods aplied on the solid fired bricks, which are intended for reconstruction of the bridge in Sedlec. There are monitored changes in structure of solid fired bricks caused by repeated freezing and defrosting. This changes are monitored by resonant frequency method and ultasonic pulse method.

This thesis deals with building survey of bridge register number 43-011 located near Česká. The part of thesis is literary reaserch dealing with system of management and cotrol of road bridges, precast bridge contructions made with DS-C type girgers and about general diagnostical methods. The practical section contains of in situ diagnostical survey and bridge inspection, laboratory evaluation and comparision, load bearing capacity calculation and suggestion of potencional technical precautions.

The aim of this thesis is to evaluate the real condition of reinforced concrete beam bridge located in Brno Jundrov. In order to evaluate this condition, there was made the main bridge inspection. Subsequently, a number of diagnostic methods were used, such as hardness tests, concrete stress strenght, ultrasonic pulse method, including their evaluation. In terms of the main inspection, the condition of construction of the bridge was evaluated as V - bad. We found out that the concrete from which the bridge is built of is in very good condition. The problem, however, is the condition of the reinforcement located on the bridge. Based on its condition there must be expected lifespan within the next 5-10 years.

This diploma thesis is divided into two parts, theoretical and practical. The is a review om the topic of recycled asphalt pavement and recycled concrete and their possible use in road construction in the theoretical part. The individual chapters deal with describing these materials, their production, and their use in construction layers of pavements. In the next chapters the attention is also paid to their problematic features and foreign experience using these materials in pavements. In the practical part, laboratory samples of recycled asphalt pavement and recycled concrete and their mixtures with cement are tested. The main purpose is to verify the applications of these mixtures of recycled asphalt pavement and recycled concrete in the bonded base layers of the pavement. Another purpose is to compare how these mixtures individual properties with different proportions of both components and different amounts of cement will be different. In the end, the two mixtures with the best properties was selected and the modulus of elasticity was experimentally determined for the possibility of replacing the currently used base layers and the economic evaluation of this design was made.

The master thesis focuses on the design of sanitary and gas installations in the particular aparthotel building in Pec pod Sněžkou. It is an aparthotel with two underground and max six above-ground floors incl. a gallery. The upper floors of the towers are used for accommodation. A parking lot and wellness area are situated on the first underground floor. On the second underground floor there is a technical background of the building, shops and a small restaurant for guests. All the roofs and terraces of the aparthotel are made to be green. The calculation part and the project contain the design of the sewerage, water supply, gas pipeline and their connection to the existing engineering networks. The theoretical part deals with increasing the pressure in the indoor plumbing, incl. design of equipment for increasing the pressure in the particular building.