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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 11 to 20 of 304 (0.022 seconds)Spelling suggestions: "subject:"tumour.""
| 11 |
The clinical perspective on malignancies in renal transplanted patientsHellström, Vivan January 2016 (has links)
Post-transplant malignancies cause significant morbidity and mortality. In this thesis we investigated malignancies in renal transplanted patients from a clinical viewpoint. The use of regional tumour registries considerably improved identification of pre- and post-transplant malignancies, which are generally underreported in transplant registries. Despite previously adequate cancer treatments with favourable prognosis, patients with pre-transplant malignancies showed higher incidence of post-transplant cancer and reduced survival compared to a 1:3 ratio matched control group of patients without a previous cancer from the Collaborative Transplant Study in Europe. A careful oncological surveillance pre-transplant and post-transplant is recommended. A multidisciplinary team evaluated the immunosuppressive and oncological treatment in a clinical prospective observational study of 120 renal transplanted patients with post-transplant malignancies. In two-thirds of the patients immunosuppression was possible to change to mTOR inhibitors with anti-tumour effects. Oncological treatment was adjusted in 50% of patients with solid or haematological tumours. MDT assessments are essential for optimizing treatment of post-transplant malignancies. Number of previous cutaneous squamous cell carcinoma (SCC) posed the most significant risk variable in predicting subsequent SCCs during a two-years study of 73 transplanted patients with at least one SCC. Incidence of transplant-derived tumours is 5 times higher than anticipated. Three of eleven cancers in urinary tract and two of four cancers in the transplants were transplant-derived. Five of eleven cancers of the urinary tract were BK-virus positive. Allograft immune response against these tumours offer new options for cancer treatment such as immunomodulatory or anti-viral treatment in combination with modified immunosuppression.
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| 12 |
Investigations of putative tumour suppressor loci in human malignancyBruce, Christopher Kenneth January 2001 (has links)
No description available.
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| 13 |
The role of transcription factor AP-1 and gelatinases in oral carcinogenesis and their regulation by transforming growth factor betaRobinson, Conrad Maxwell January 1999 (has links)
No description available.
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| 14 |
A study of childhood rhabdomyosarcoma with respect to diagnosis, prognosis and histogenesisDias, Peter Bento Ernest January 1989 (has links)
No description available.
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| 15 |
Evaluation of mechanisms underlying the proliferative and invasive behaviour of gliomaKoochekpour, Shahriar January 1996 (has links)
No description available.
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| 16 |
Cell lineage analysis of the liver and the intestinal epithelium of the mouseO'Sullivan, John F. January 1990 (has links)
No description available.
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| 17 |
Proton nuclear magnetic resonance studies of human glioma cell linesFlorian, Catarina Ligia January 1996 (has links)
No description available.
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| 18 |
Transcriptional regulation by Brn 3 POU domain containing transcription factorsDennis, Jonathan Hancock January 2001 (has links)
No description available.
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| 19 |
Defective mismatch repair and DNA damage sensing in human cellsO'Driscoll, Mark John January 1999 (has links)
No description available.
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| 20 |
Monoclonal antibodies for the study of colorectal and other carcinomasMakin, Carol Audrey January 1985 (has links)
No description available.
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