Amostras indeformadas de um solo residual foram coletadas na zona oeste da cidade de São Paulo com o intuito de caracterizar o solo e estudar seu comportamento mecânico. Sua composição mineralógica é apresentada, assim como um estudo microscópico que identifica alguns destes minerais e evidencia sua microestrutura. Desse modo, é discutido como sua mineralogia e microestrutura influenciam em seu comportamento mecânico, estudado por meio de ensaios edométricos e de ensaios triaxiais convencionais de carregamento axial. Analisou-se sua compressibilidade, permeabilidade, seu grau de estruturação, suas relações tensão-deformação e envoltórias de escoamento, de ruptura e de Estados Críticos. O solo foi caracterizado como saprolítico, proveniente de um biotita-gnaisse milonitizado. A partir dos resultados obtidos a respeito do comportamento do solo, três modelos constitutivos escolhidos para estudo foram calibrados: elástico linear, elasto-plástico perfeito (Mohr-Coulomb) e elasto-plástico com endurecimento (Hardening-Soil). Com esta modelagem matemática, foi concebida uma modelagem numérica tridimensional de elementos finitos, a fim de simular a escavação de um túnel e de obter as trajetórias de tensões atuantes ao seu redor devidas a sua escavação. Outros ensaios triaxiais foram executados, desta vez seguindo-se as trajetórias de tensões obtidas numericamente. Os parâmetros elásticos dos três modelos constitutivos foram determinados para cada trajetória de tensões e o maciço envolvente à escavação foi modelado como sendo mecanicamente heterogêneo. Ou seja, limitaram-se zonas ao redor do túnel com diferentes propriedades mecânicas em função da trajetória de tensões atuante. Por fim, são comparados os parâmetros geotécnicos determinados com diferentes trajetórias de tensões, assim como os resultados obtidos com ambas as modelagens numéricas. / Undisturbed samples of a residual soil had been collected from the west zone of São Paulo city, in order to characterize the soil and study its mechanical behaviour. Its mineralogical composition is presented, as well as a microscopic study which identifies some of these minerals and evinces its microstructure. Thus, how the soil mineralogy and microstructure influence its mechanical behaviour is discussed, which was studied by means of oedometer tests and conventional axial loading triaxial tests. One analysed the soil compressibility, permeability, structuring degree, stress-strain relations and yielding, rupture and Critical State envelopes. The soil had been characterized as saprolite, derived from a biotite-gneiss. Based on the results concerning the soil behaviour, three constitutive models were calibrated: linear elastic, elastic perfectly plastic (Mohr-Coulomb), and elastic-plastic with hardening (Hardening Soil). With this mathematical modelling, a three-dimensional numerical model with finite elements was designed, for the purpose of simulating a tunnel excavation and obtaining the stress paths around it due to its excavation. Other triaxial tests were carried out, this time by following the stress paths numerically obtained. The elastic parameters of the three constitutive models had been determined for each stress path and the ground surrounding the excavation had been modelled as a mechanically heterogeneous media. I.e., zones around the tunnel had been limited by its different mechanical properties, as a function of the actual stress path. Finally, the geotechnical parameters determined by different stress paths are compared, as well as the results obtained for both numerical models.

Atualmente, a escavação de túneis rasos em regiões densamente ocupadas requer medidas severas para reduzir riscos e possíveis influências em estruturas próximas. Um importante passo é a previsão dos efeitos da escavação, principalmente no que concerne à geração de recalques. As redes neurais artificiais (RNAs) aparecem como uma nova ferramenta para auxiliar o entendimento desses fenômenos. Isso porque a rede neural possui a capacidade de realizar generalizações, isto é, após a rede aprender características de uma categoria geral de dados baseada em uma série de exemplos daquela categoria, a rede pode apresentar respostas idênticas ou similares às respostas treinadas para entradas não treinadas. Nesse trabalho, realiza-se a aplicação de redes neurais artificiais para os dados das linhas 1 e 2 do metrô de São Paulo, onde se observa a influência de alguns parâmetros e a melhoria significativa de previsão da rede neural devido à utilização de algumas técnicas no tratamento e manuseio dos dados. Dentre as técnicas de tratamento de dados utilizadas destaca-se a adimensionalização dos dados por parâmetros da própria obra garantindo melhor estabilidade à rede e melhor capacidade de previsão. Análises de sensibilidade também são realizadas para contemplar o tipo de influência que cada parâmetro exerceu nos recalques obtidos. / Excavating shallow tunnels in densely occupied areas currently requires strict precautions to reduce risks and possible effects on nearby structures. Being able to predict excavation effects and particularly settlement - related effects is an important step forward in this respect. Artificial neural networks (ANNs) have emerged as a new tool for analyzing geotechnical problem. Longstanding problems have been solved and conventional solutions enhanced as the ability to generate more information grows and the understanding of obscure points is deepened. Neural networks have the ability to make generalizations: once a network has learned the characteristics of a general category of objects based on a series of examples from this category, it can provide identical or similar responses to trained responses for non-trained inputs. This study uses artificial neural networks to analyze data from São Paulo subway line 1 and 2 to observe the effects of certain parameters and notes significantly enhanced neural network predictive ability due to the use of certain data processing techniques. The study also sets out to show that the use of dimensionless data in training may upgrade the predictive ability of the model. Knowledge acquired was applied to further develop use of this technique for tunnel instrumentation.

Made available in DSpace on 2017-07-10T17:31:12Z (GMT). No. of bitstreams: 1 Cleverson_Holocheski.pdf: 3361676 bytes, checksum: 7e3dfcfe4af0abe5639e043c72615586 (MD5) Previous issue date: 2011-08-05 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Whereas erosion is a process that detracts from the soil, reducing its productivity or even making impossible the food production in it, it is worth emphasizing the importance of studies on this topic, especially with explanations and solutions to problems found in areas that are degraded by erosive processes. The installation and evolution of this process depends on a number of factors, all of them related to the pedological cover and the shapes of slopes, such as those linked to the hydrology of the hillside. With emphasis on this type of erosion phenomenon, this work takes as its main objective to recognize the factors correlated with onset and progression of tunnels, particularly those concerning the characteristics of soils and landforms in a hillside of Rio das Pombas, in the city of Guarapuava, South Center of the Paraná State. To this end, the research was developed from a comprehensive pedological system approach, identifying and individualizing the units of soil through surveys, and also monitoring the rainfall and hydrological flows in order to observe the dynamics of subsurface water in that slope. The methodology used in the study was divided into four phases with the first phase was consisted basically of bibliographic content to be worked, then the second part of the research was carried out on field work, and in this phase samples for laboratory analysis were collected; the piezometers for monitoring of subsurface flows were installed and it was also installed the weather station to the collections related to rainfall. In the third phase, the work was focused on laboratory and office, where were then carried out the sizing analysis and also the preparation of cartographic material combined with the tabulation of data for the construction of graphs. The fourth and final phase was the analysis of integrated data, from which, through the analysis the results were achieved. In the case studied, the results indicated that the main factors of installation and maintenance of erosion of those tunnels were that related to the physical properties of pedologic cover, such as the particle size, the shape of the slope and mainly the hydrological conditions. Regarding the evolution of the erosion on that slope, it can be said that the tunnels in the future may finally become a crater, damaging the use of the area. / Considerando que a erosão é um processo que deprecia o solo diminuindo a sua produtividade ou até mesmo impossibilitando a sua produção de alimentos, cabe ressaltar, a importância de estudos sobre essa temática, principalmente, com explicações e soluções para os problemas encontrados em áreas degradadas por processos erosivos. A instalação e evolução da erosão em túneis depende de uma série de fatores, tanto aqueles relativos à cobertura pedológica e as formas das vertentes, como aqueles vinculados à hidrologia da encosta. Com destaque para esse tipo de fenômeno erosivo, o presente trabalho, adota como objetivo principal reconhecer os fatores correlacionados a instalação e evolução de túneis, particularmente, aqueles relativos às características dos solos e das formas de relevo, em uma encosta do Rio das Pombas, Município de Guarapuava, Centro Sul do Estado do Paraná. Para tanto, a pesquisa desenvolveu-se a partir de uma abordagem detalhada do sistema pedológico, identificando e individualizando as unidades de solo através de sondagens e também, monitorando as precipitações e os fluxos hidrológicos, a fim de, observar à dinâmica subsuperficial da água na referida encosta. A metodologia utilizada na pesquisa dividiu-se em quatro fases, sendo que a primeira fase consistiu basicamente no levantamento bibliográfico do conteúdo a ser trabalhado, em seguida na segunda parte da pesquisa realizou-se os trabalhos de campo, sendo que nessa fase foram coletadas as amostras para análises em laboratório; instalados os piezômetros para o monitoramento dos fluxos subsuperficiais e também instalada a estação meteorológica, para as coletas referentes às precipitações. Na terceira fase os trabalhos concentraram-se em laboratório e em gabinete, onde então foram realizadas as análises granulométricas e também a confecção do material cartográfico juntamente com a tabulação dos dados para confecção dos gráficos. Na quarta e última fase ocorreu à análise integrada dos dados, de onde então através dessa análise chegou-se aos resultados da pesquisa. No caso estudado, os resultados apontam que os principais fatores de instalação e manutenção de erosão dos túneis foram àqueles referentes às propriedades físicas da cobertura pedológica, tais como, a composição granulométrica, a forma da encosta e principalmente as condições hidrológicas. No que diz respeito à evolução do processo erosivo na referida encosta, pode-se afirmar que os túneis futuramente poderão chegar a se tornar uma voçoroca, prejudicando utilização da área.

Made available in DSpace on 2017-05-12T14:42:44Z (GMT). No. of bitstreams: 1 Cleverson_Holocheski.pdf: 3361676 bytes, checksum: 7e3dfcfe4af0abe5639e043c72615586 (MD5) Previous issue date: 2011-08-05 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Whereas erosion is a process that detracts from the soil, reducing its productivity or even making impossible the food production in it, it is worth emphasizing the importance of studies on this topic, especially with explanations and solutions to problems found in areas that are degraded by erosive processes. The installation and evolution of this process depends on a number of factors, all of them related to the pedological cover and the shapes of slopes, such as those linked to the hydrology of the hillside. With emphasis on this type of erosion phenomenon, this work takes as its main objective to recognize the factors correlated with onset and progression of tunnels, particularly those concerning the characteristics of soils and landforms in a hillside of Rio das Pombas, in the city of Guarapuava, South Center of the Paraná State. To this end, the research was developed from a comprehensive pedological system approach, identifying and individualizing the units of soil through surveys, and also monitoring the rainfall and hydrological flows in order to observe the dynamics of subsurface water in that slope. The methodology used in the study was divided into four phases with the first phase was consisted basically of bibliographic content to be worked, then the second part of the research was carried out on field work, and in this phase samples for laboratory analysis were collected; the piezometers for monitoring of subsurface flows were installed and it was also installed the weather station to the collections related to rainfall. In the third phase, the work was focused on laboratory and office, where were then carried out the sizing analysis and also the preparation of cartographic material combined with the tabulation of data for the construction of graphs. The fourth and final phase was the analysis of integrated data, from which, through the analysis the results were achieved. In the case studied, the results indicated that the main factors of installation and maintenance of erosion of those tunnels were that related to the physical properties of pedologic cover, such as the particle size, the shape of the slope and mainly the hydrological conditions. Regarding the evolution of the erosion on that slope, it can be said that the tunnels in the future may finally become a crater, damaging the use of the area. / Considerando que a erosão é um processo que deprecia o solo diminuindo a sua produtividade ou até mesmo impossibilitando a sua produção de alimentos, cabe ressaltar, a importância de estudos sobre essa temática, principalmente, com explicações e soluções para os problemas encontrados em áreas degradadas por processos erosivos. A instalação e evolução da erosão em túneis depende de uma série de fatores, tanto aqueles relativos à cobertura pedológica e as formas das vertentes, como aqueles vinculados à hidrologia da encosta. Com destaque para esse tipo de fenômeno erosivo, o presente trabalho, adota como objetivo principal reconhecer os fatores correlacionados a instalação e evolução de túneis, particularmente, aqueles relativos às características dos solos e das formas de relevo, em uma encosta do Rio das Pombas, Município de Guarapuava, Centro Sul do Estado do Paraná. Para tanto, a pesquisa desenvolveu-se a partir de uma abordagem detalhada do sistema pedológico, identificando e individualizando as unidades de solo através de sondagens e também, monitorando as precipitações e os fluxos hidrológicos, a fim de, observar à dinâmica subsuperficial da água na referida encosta. A metodologia utilizada na pesquisa dividiu-se em quatro fases, sendo que a primeira fase consistiu basicamente no levantamento bibliográfico do conteúdo a ser trabalhado, em seguida na segunda parte da pesquisa realizou-se os trabalhos de campo, sendo que nessa fase foram coletadas as amostras para análises em laboratório; instalados os piezômetros para o monitoramento dos fluxos subsuperficiais e também instalada a estação meteorológica, para as coletas referentes às precipitações. Na terceira fase os trabalhos concentraram-se em laboratório e em gabinete, onde então foram realizadas as análises granulométricas e também a confecção do material cartográfico juntamente com a tabulação dos dados para confecção dos gráficos. Na quarta e última fase ocorreu à análise integrada dos dados, de onde então através dessa análise chegou-se aos resultados da pesquisa. No caso estudado, os resultados apontam que os principais fatores de instalação e manutenção de erosão dos túneis foram àqueles referentes às propriedades físicas da cobertura pedológica, tais como, a composição granulométrica, a forma da encosta e principalmente as condições hidrológicas. No que diz respeito à evolução do processo erosivo na referida encosta, pode-se afirmar que os túneis futuramente poderão chegar a se tornar uma voçoroca, prejudicando utilização da área.

The deployment of engineering models and design methods divorced from the effect that mechanised shield tunnelling with tunnel boring machines (TBMs) has on concrete segmental linings (CSLs) can lead to either material waste or structural damage within the tunnel design life. Most research to date on CSL behaviour during construction neglects the sequential ring loading and TBM-lining transverse interactions, which this thesis proved to be key in the short and long term behaviour of CSLs and whose study is essential if the design and maintenance of CSL structures is ever to be optimised. This thesis investigates the longitudinal and transverse behaviour of CSL structures simultaneously backfilled with bicomponent grouts (BGs) during tunnelling, and how this early response influences long term behaviour. The research work is drawn on three pillars that enable cross-validation of conclusions: analytical models, three-dimensional numerical simulations and the interpretation of the Crossrail's Thames tunnel (CTT) field data, which included distributed fibre optic strain (DFOS) data. A theoretical framework ranging from construction loading scenarios to the mechanisms underlying structural damage is described for the future development of limit state design methods. Analytical models of longitudinal behaviour are also proposed. The study of joint geometries, temporary spear bolts and DFOS sensing in CSL construction monitoring is included as ancillary research. The solution developed for a sequential elastic rod subjected to a trilinear temperature profile and in shear interaction with the elastic ground predicts accurately the early tunnel pre-stressing relaxation caused by grout hardening, e.g. ≈50% in the CTT. The proposed sequential elastic beam model, which incorporates the effects of stage-varying net TBM moments, transverse loads and lining pressure gradients within the tunnel unsupported length, estimates satisfactorily the history of tunnel beam response during construction for a realistic expression of the lining stiffness. A potential damage assessment method for the early detection of tunnel sections prone to ring joint damage was proposed. The TBM-lining transverse interaction determines the CSL ring behaviour at the early stages of tunnelling. The ring response resultant from this interaction is irrecoverable and contributes to the long term total deformations and internal forces; in tunnels excavated in grounds with Ko≈1, it becomes the major source of ring distortion. The main transverse actions are the sealing pressures, which are inversely related to the tail clearance, and the transverse load of oblique hydraulic jacks. When the non-bedded rings are eccentric with respect to the shield tail, the ring distortion increases the risk of cracking near the rear corners and spalling at the ram pad interspaces of constrained segments. The ring distortion is directly related to the pressure gradients, the unsupported length and the ring flexibility. When individual segments rotate outwards under the action of transverse ram loads, e.g. the outer springline segment during pronounced TBM steering around a horizontal curve, the localised action of the sealing pressures can result in longitudinal cracking at the intrados of the segment front. This study represents a qualitative leap towards the optimisation of CSL design, shifting the attention of researchers and designers to TBM-lining transverse interactions as the most determinant factor of structural response during construction in CSLs simultaneously backfilled with BGs.

Atualmente, a escavação de túneis rasos em regiões densamente ocupadas requer medidas severas para reduzir riscos e possíveis influências em estruturas próximas. Um importante passo é a previsão dos efeitos da escavação, principalmente no que concerne à geração de recalques. As redes neurais artificiais (RNAs) aparecem como uma nova ferramenta para auxiliar o entendimento desses fenômenos. Isso porque a rede neural possui a capacidade de realizar generalizações, isto é, após a rede aprender características de uma categoria geral de dados baseada em uma série de exemplos daquela categoria, a rede pode apresentar respostas idênticas ou similares às respostas treinadas para entradas não treinadas. Nesse trabalho, realiza-se a aplicação de redes neurais artificiais para os dados das linhas 1 e 2 do metrô de São Paulo, onde se observa a influência de alguns parâmetros e a melhoria significativa de previsão da rede neural devido à utilização de algumas técnicas no tratamento e manuseio dos dados. Dentre as técnicas de tratamento de dados utilizadas destaca-se a adimensionalização dos dados por parâmetros da própria obra garantindo melhor estabilidade à rede e melhor capacidade de previsão. Análises de sensibilidade também são realizadas para contemplar o tipo de influência que cada parâmetro exerceu nos recalques obtidos. / Excavating shallow tunnels in densely occupied areas currently requires strict precautions to reduce risks and possible effects on nearby structures. Being able to predict excavation effects and particularly settlement - related effects is an important step forward in this respect. Artificial neural networks (ANNs) have emerged as a new tool for analyzing geotechnical problem. Longstanding problems have been solved and conventional solutions enhanced as the ability to generate more information grows and the understanding of obscure points is deepened. Neural networks have the ability to make generalizations: once a network has learned the characteristics of a general category of objects based on a series of examples from this category, it can provide identical or similar responses to trained responses for non-trained inputs. This study uses artificial neural networks to analyze data from São Paulo subway line 1 and 2 to observe the effects of certain parameters and notes significantly enhanced neural network predictive ability due to the use of certain data processing techniques. The study also sets out to show that the use of dimensionless data in training may upgrade the predictive ability of the model. Knowledge acquired was applied to further develop use of this technique for tunnel instrumentation.

Le travail de thèse porte sur la conception et le développement d'une technique de modélisation de la propagation d'ondes radioélectriques dans des tunnels non rectilignes de section non droite rencontrés en milieu ferroviaire. Les solutions développées sous forme de modules appelés ≪ plugin ≫, ont été ajoutées au noyau de l'outil de modélisation de la propagation d'ondes, RaPSor, issu des recherches menées par le laboratoire XLIM-SIC de l'Université de Poitiers. Dans ce travail, nous avons montre que les techniques classiques mises en œuvre afin de modéliser la propagation des ondes en tunnel rectiligne infini de section rectangulaire, ne peuvent pas être transposées au cas des tunnels courbes de section courbe. Apres avoir rappelé les différentes méthodes disponibles, nous avons testé une technique de facettisation de la section courbe d'un tunnel rectiligne avec le tracé de rayons existant dans RaPSor, puis avec un lancer de rayons développé et implémenté au cours de la thèse. Les limites de cette technique de facettisation ont été mises en évidence. La deuxième partie du travail représente le cœur du travail de thèse. Nous avons développé une méthode qui se fonde sur une représentation analytique spécifique des surfaces courbes associée à un lancer de rayons et une optimisation originale des trajets reçus. La répartition uniforme des rayons lancés à l'émission repose sur l'utilisation de séquences quasi-aléatoires de Hammersley. Une sphère adaptative est utilisée à la réception. L'optimisation des rayons reçus est réalisée avec la technique de minimisation de Levenberg-Marquardt. Il s'agit de minimiser la distance totale des trajets afin d'approcher les trajets réels au sens de l'Optique Géométrique. L'ensemble des méthodes développées ont été testées et validées par comparaisons avec des résultats de la littérature mais aussi avec des résultats de mesures réalisées par le LEOST et ALSTOM-TIS

Thesis (Ph. D.)--Ohio State University, 2006. / Title from first page of PDF file. Includes bibliographical references (p. 114-120).

No description available.

Carbamoyl phosphate synthetase (CPS) from E. coli catalyzes the formation of carbamoyl phosphate, an intermediate in the biosynthesis of pyrimidine nucleotides and arginine, from glutamine, bicarbonate and two molecules of MgATP. This reaction is catalyzed by three separate active sites that are separated in space by ~100 Å. The transfer of ammonia and carbamate through the two intramolecular tunnels was investigated by molecular dynamics simulations and experimental characterization of mutations within. The presence of an unstable reaction intermediate, carboxyphosphate, was established. A method for studying the synchronization of the two active sites on the large subunit of CPS was developed. The potential of mean force (PMF) calculations along the ammonia and carbamate transfer pathways indicate a low free-energy path for the translocation of ammonia. The highest barrier for ammonia is 7.2 kcal/mol which corresponds to a narrow turning gate surrounded by the side chains of Cys-232, Ala-251, and Ala-314 in the large subunit. A blockage in the passageway was introduced by the triple mutant C232V/A251V/A314V, which was unable to synthesize carbamoyl phosphate. The release of phosphate is necessary for the injection of carbamate into the carbamate tunnel. Two mutants, A23F and G575F, were designed to block the migration of carbamate through carbamate tunnel. The mutants retained only 1.7 percent and 3.8 percent of the catalytic activity for the synthesis of carbamoyl phosphate relative to the wild-type CPS, respectively. Formate can be utilized by CPS in the absence of bicarbonate to form formyl phosphate. This intermediate was observed by 31P, 13C, and 1H NMR. For the three NMR methods a peak corresponding to formyl phosphate was observed at 2.15 ppm (31P) , 162.4 ppm (13C), and 8.39 and 7.94 ppm (1H). The rate of formation of formyl phosphate is 0.025 ± 0.005 s-1. Formamide was not detected in the presence of an ammonia source. Fluorescence anisotropy measurements on the C551A/S171C and C551A/S717C mutants provided insight into a possible mechanism of synchronization between the two active sites on the large subunit. The biggest fluorescence anisotropy change was observed at the N-terminal domain in the presence of AMPPNP and ATP.