Previous studies raise debates on which factors significantly affect the economic growth in different countries in Sub-Saharan Africa. Therefore, the purpose of our study is to examine and analyze how the selected macroeconomic factors can have different effects on economic growth in Sub-Saharan Africa. To concretize this, a panel data and regression analysis have been applied to 36 countries in Sub-Saharan Africa during the period of 2006-2019. The thesis is composed of data over corruption index, foreign direct investment (FDI), GDP per capita growth, population growth, education, economic freedom, and socioeconomic indicators such as political rights. To investigate these factors various macroeconomics theories have been applied, such as the Solow, Romer and Kremerian model, which explains the impact of population growth andeducation on economic growth. Moreover, the Electric Paradigm (OLI), the Institutional theory and some previous studies have been used to explain the effect of corruption, FDI, economic freedom, and political rights on economic growth. A linear regression model was made in the econometric panel data analysis to investigate the selected factors. The result of this study shows that population growth and economic freedom have a significant impact on economic growth. Other factors, however, were statistically nonsignificant.