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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
141

Article VI: Assistance and Protection against Biological and Toxin Weapons

Pearson, Graham S., Sims, N.A. January 2000 (has links)
Yes
142

Effects of Federal Grant Money on Economic Measures in the Community

Miller, Andrea L 01 January 2016 (has links)
With the concentration of poverty increasing throughout the United States (Kneebone, 2014) there has been a recent emphasis on mixed-income housing as a means to alleviate this issue. By creating housing in one area with pricing for different income levels it is assumed that the burden imposed by concentrated poverty will be lowered. Many years and many dollars later however, the results of mixed-income housing projects on low-income residents seem to be mixed – while some projects have found success, others seem to suggest that it has little to no effect. The federal program HOPE VI is one example of efforts to increase the availability of mixed-income housing. It is the purpose of this study to decipher whether the administration of HOPE VI federal grant money has had an effect on certain economic outcomes within the selected metropolitan areas.
143

A PHOTOLUMINESCENCE SCALING STUDY OF CdSe/ZnSe SELF ASSEMBLED QUANTUM DOTS

JONES, ROBERT A. 03 December 2001 (has links)
No description available.
144

STUDIES IN THE ARCHAEOLOGY OF HELLENISTIC PONTUS: THE SETTLEMENTS, MONUMENTS, AND COINAGE OF MITHRADATES VI AND HIS PREDECESSORS

Arikan Erciyas, Deniz Burcu 11 October 2001 (has links)
No description available.
145

The Role of Type VI Collagen In Cardiac Remodeling Following Myocardial Infarction In Mice.

Luther, Daniel J. 12 August 2013 (has links)
No description available.
146

Cr(VI) reduction by Fe(II)-dissolved organic matter complexes and the characterization of pore water dissolved organic matter from a coastal wetland in the Laurentian Great Lakes

Agrawal, Sheela G. January 2008 (has links)
No description available.
147

Characterization of Novel Type VI Effectors of Acidovorax citrulli and Their Applicability to Biological Control of Plant Diseases

Wang, Kunru 31 March 2022 (has links)
Bacterial secretion systems have been playing essential roles in modulating the microbiota of most ecological niches. Among a variety of secretion systems, the Type VI Secretion System (T6SS), a nanomachine widely distributed in Gram-negative bacteria, is gaining increasing attention due to its involvement in microbe-microbe and microbe-host interactions through secreting toxins into host cells, microbial competitors, and the extracellular milieu. Most secreted toxins, also known as T6SS effectors, have bacteriostatic effects upon delivery into competing bacteria, and therefore bacteria with potent T6SS may acquire competition advantage and represent promising biological control agents (BCAs). The main body of this dissertation will focus on the characterization of the T6SS of a phytopathogen, Acidovorax citrulli (strain AAC00-1), and the secreted T6 effectors, and will also discuss the possible application of AAC00-1 as a BCA. The seed-borne, gram-negative A. citrulli is able to cause bacterial fruit blotch (BFB) disease and then result in devastating decrease in yields of important cucurbits including watermelon, melon, squash and cucumber. Our inter-microbial competition assays demonstrate that AAC00-1 contains an active T6SS and presents a dramatic antimicrobial activity against a variety of microbes, including Gram-negative bacteria, Gram-positive bacteria, and yeast, dependent upon its T6SS. A group of novel non-enzymatic effectors, Hyde1 proteins, delivered into prey cells through the T6SS, are responsible for this broad-spectrum antimicrobial activity. Expressing Hyde1 or its N-terminal transmembrane domain shows significant toxicity in both E. coli and AAC00-1, and the toxicity of Hyde1 can be counteracted by its immunity protein, Hyde2. A non-pathogenic AAC00-1 strain suppresses the growth of multiple deleterious phytopathogens in planta and protects plant host. Transgenic plants expressing either full-length Hyde1 or its transmembrane domain demonstrate improved resistance against both bacterial and oomycete pathogens. Altogether, we characterize the T6SS killing of AAC00-1, identify the determinant effectors and discuss the application of both AAC00-1 and its T6SS effector in plant disease management. Additionally, in order to develop molecular tools better serving our T6SS-related studies, we successfully generate a series of salicylic acid (SA)-inducible vectors, functioning in A. citrulli, that can be used for inducible gene expression, protein purification and other applications. The core regulatory component that we employ, is a transcriptional regulator, Sal7AR-V295F, due to its responsiveness to salicylate. By cloning this fragment to a broad-host-range plasmid, in this study, we establish multiple SA-inducible vectors that may be used in most Gram-negative bacteria. When using the E. coli strain C41(DE3) as the expression host, protein purification can be conducted routinely, upon the addition of affinity tags to our vectors, such as the maltose-binding protein (MBP) tag. Combining the modified vectors with the robust NanoLuc binary Technology (NanoBiT), we are able to devise a novel bacteria two-hybrid system as an effective method to detect protein-protein interaction. Two complementary fragments of the NanoLuc protein, LgBiT and SmBiT, with extremely low affinity, are fused to potential interactors, and they will be brought into proximity and reconstitute NanoLuc bioluminescence upon the occurrence of interaction. This system is used in our T6SS study to validate the interaction between Hyde1 toxin and its cognate immunity protein. Another fragment, HiBiT, which automatically interacts with LgBiT and reconstitutes NanoLuc, is cloned to the SA-inducible vector as well, enabling us to generate a split-NanoLuc-based method, for the purpose of detecting secretion of tagged T6 toxins into the prey bacterial cells expressing LgBiT. Overall, our SA-inducible vectors and their further modifications enrich the molecular tool repertoire for T6SS-related studies. / Doctor of Philosophy / Effective crop disease management is critical for agricultural production. Chemical spray has been practiced as one major approach to control plant diseases for more than a decade. However, increase of pesticide application could threaten public health and the environment. Biological control has been considered as one of the effective and environmental-friendly alternative approaches for disease control. In this dissertation, we identify that, Acidovorax citrulli (strain AAC00-1), a Gram-negative pathogen causing bacterial fruit blotch (BFB) disease in Cucurbitaceae, could be a potential biological control agent (BCA), because it carries an active Type VI Secretion System (T6SS), and the T6SS has been shown to contribute to the protective effects of many plant-associated BCAs. T6S is believed to mediate inter-bacterial competition through secreting toxins into microbial competitors. Most secreted toxins, also known as T6SS effectors, have bacteriostatic effects upon delivery into competing bacteria, and therefore bacteria with potent T6SS may acquire competition advantage and represent promising BCAs. We demonstrate that AAC00-1 suppresses the growth of multiple phytopathogens, depending upon its T6SS. Expressing ten out of eleven microbial toxins, encoded by Hyde1 genes, in E. coli shows significant toxicity. The wild type AAC00-1 strain inhibits the growth of multiple Arabidopsis leaf bacterial isolates, while an AAC00-1 Hyde1 mutant loses this capacity. The antimicrobial activity of AAC00-1 is proven to be broad-spectrum since this strain also shows inhibitory effect on the growth of Gram-positive bacteria and yeast. In planta disease assay suggests that a non-pathogenic AAC00-1 mutant defective in Type III secretion system (T3SS) maintains its capacity to suppress disease symptoms and pathogen growth on plants infected with different phytopathogens. Our study demonstrates the viability of the employment of non-pathogenic A. citrulli as an effective BCA in plant disease management.
148

The role of type VI secretion systems in the competitive ability of Escherichia coli strain D12

Cekol, Ana January 2024 (has links)
No description available.
149

Évaluation herméneutique des traductions du mot àpoevokoïtal en 1 Co 6,9 / Évaluation herméneutique des traductions du mot ἀρσενοκοῑται en 1 Co 6,9 / Évaluation herméneutique des traductions du mot arsenokoitaï en 1 Co 6,9

Doyon, François 01 October 2024 (has links)
La présente étude examine les difficultés de traduction et d'interprétation du mot grec ἀρσενοκοῖται (*arsenokoitaï*) qu'on trouve dans les versets 1 Co 6,9 et 1 Tm 1,10 du Nouveau Testament de la Bible. Par l'analyse du contexte historique et littéraire du mot, l'étude de l'homosexualité en contextes grec, romain et hébraïque ainsi que sa représentation dans diverses traductions de la Bible, nous remettons en question les interprétations courantes qui associent ἀρσενοκοῖται à l'homosexualité, à la sodomie ou à la pédérastie. L'usage spécifique de ce mot dans le Nouveau Testament est difficile à déterminer, car il semble être un néologisme paulinien. De plus, sa traduction par *homosexual* dans certaines éditions actuelles de la Bible peut contribuer à la discrimination et aux violences envers la communauté LGB. La présente étude suggère une approche plus rigoureuse de la traduction du mot afin de respecter les complexités sémantiques et contextuelles et d'éviter la stigmatisation de personnes vulnérables. / This study examines the translation and interpretation challenges of the Greek word ἀρσενοκοῖται (*arsenokoitai*) found in the New Testament of the Bible, verses 1 Cor 6:9 and 1 Tim 1:10. By analyzing the historical and literary context of this word, a study of homosexuality in Greek, Roman and Hebrew contexts as well as its representation in various translations of the Bible, we challenge common interpretations that associate ἀρσενοκοῖται with homosexuality, sodomy or pederasty. The specific use of this word in the New Testament is difficult to determine, as it appears to be a neologism created by Paul. Furthermore, its translation as *homosexual* in some current editions of the Bible may contribute to discrimination and violence against the LGB community. This study suggests a more rigorous approach to the translation of this word by considering semantic and contextual complexities in order to avoid stigmatizing vulnerable people.
150

Energieffektivisering av sjöfarten : En studie om att implementera obligatoriska riktlinjer / Making shipping energy efficient : A study regarding implementing mandatory guidelines

Falk, David, Niklasson, Markus January 2014 (has links)
Vi lever i en värld av klimatförändringar där det ständigt söks efter lösningar för att minska utsläppen av växthusgaser. IMO har infört SEEMP:en med målet att reducera utsläppen från världshandelsflottan och därmed öka dess energieffektivitet. Med denna bakgrund har syftet varit att undersöka hur svenska tankrederier implementerat och tillämpat SEEMP:en samt kartlägga åsikter kring den. En kvalitativ metod har använts för att på djupet undersöka rederiernas tillvägagångssätt. Undersökningen omfattar fyra semistrukturerade intervjuer med totalt sex personer ifrån två rederier där både ombord- och landanställda finns representerade. Resultatet visade att rederierna implementerat SEEMP:en efter IMO:s riktlinjer, i samråd med sitt klassningssällskap, där rederierna också har försökt ta tillvara möjligheten att energieffektivisera sin organisation. Båda rederierna såg positivt på införandet av SEEMP:en och menade att den borde införts tidigare. Det framkommer dock faktorer som anses motverka SEEMP:ens fulla potential, bland annat att strukturen i branschen måste ändras för att kunna applicera SEEMP:en fullt ut. / We live in a world of climate change where finding a solution to reducing the emission of GHG is a continuous pursuit. To reduce the emission from global shipping IMO has adopted the SEEMP consequently making the shipping industry more energy efficient. With this in mind the purpose of this study has been to review the implementation and usage of the SEEMP among Swedish shipping companies trading oil. Furthermore, the views of the involved parties with regard to the SEEMP were also investigated. In order to deeply analyze the companies´ approach to the SEEMP a qualitative research method has been used. The study consists of four semi-structured interviews with sex persons from two shipping companies including both onshore and ship-based personnel. The result shows that the implementation has been carried out in consultation with their own classification societies and with the IMO guidelines in mind. They have also tried to take the opportunity to make their organization more energy efficient. Both companies welcomed the adoption of the SEEMP and were of the opinion that it shouldhave been introduced at an earlier stage. However, some barriers to the SEEMP have been found, for example the operational structure of the shipping industry.

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