Inaug.-diss. -- Erlangen. / Includes bibliographical references.

Akademisk avhandling--Uppsala. / Extra t.p., with thesis statement, inserted. Bibliography: p. [224]-238.

Thesis (Ph. D.)--University of Wisconsin, 1967. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliography.

The purpose of this paper was to design a simplified wind tunnel force balance for use in elementary aerodynamics/wind tunnel laboratory courses. The applied loads and moments were determined to be as follows: The design lift force is ± 20 lbs, the design drag force is ± 10 pounds, the design pitching moment is ± 20 inch-pounds. The force balance output accuracy was arbitrarily set at ± 5% since this would be sufficient for preliminary student work. The results of this work are as follows: The force balance is fabricated from a single bar of 2024 aluminum, machines and bent into an "L" shape, the applied forces and moments are sensed by strain gages bonded to machined surfaces on the bar, the output of the strain indicator equipment is transformed into uncorrected forces and moments by a system of three equations, the uncorrected forces and moments are transformed into true forces and moments by a system of force balance interaction equations, the design values for lift, drag, and pitching moment remain the same as originally proposed, the output error in lift is determined to be ± 3.5%, the output error in drag and pitching moment are determined to be ± 10%. The prototype has been in use for several months and its operation has been completely satisfactory.

The primary grain in oat spikelets is larger than the secondary grain. Oat genotypes were grown to determine the effects of planting primary and secondary grains separately on vegetative and reproductive growth. Plants from primary seeds had higher yields than those from secondary seeds. The advantage was associated with earliness of heading. It was concluded that increased seed uniformity would be advantageous. / Reductions in panicle size by removal of all primary grains and some secondary grains indicated that secondary grains have more growth potential than observed in untreated panicles. However, secondary grains in the treated panicles did not achieve weights equalling those of primary grains in the untreated panicles. / Variation in primary:secondary seed weight ratios was found among experiments. The variability was attributed mainly to instability of secondary grain weight. / The inheritance of secondary grain weight and of the primary:secondary seed weight ratio was studied at two locations. For both traits, additive and non-additive genetic effects were evident. Dominant gene action was relatively unimportant, suggesting good potential for improvement through pure-line breeding.

No description available.

Small (48-54 g) and large (58-64 g) or low (≤1.070) and high specific gravity (≥1.080) eggs from broiler breeder flocks were used. The hatching sequence was divided into four periods with 25% of the chicks being hatched in each period. One-half of each group was weighed and returned to the hatcher and the remainder were placed in floor pens. Hatch-held chicks were removed at 21 days, l2 hrs, weighed and placed in floor pens. Effect of two post-hatch holding times (0 and 30 hrs) on bursa and spleen weights were measured through 35 days of age. Hematocrits, heterophil/lymphocyte ratios, plasma proteins and glucose were measured through 11 days of age. Broilers from large vs small eggs were 10% heavier and had lower mortality at 49 days of age. Chicks that were held for extended time in the hatcher had lower body weights throughout the growing period. Held chicks had 1.6% (Exp 1) and 2.1% (Exp 2) lighter body weights at 49 days of age than removed chicks. No effect on body weight was observed for egg specific gravity. Relative bursa and spleen weights were lower in held chicks through 14 days of age. Total plasma protein (TPP) and glucose levels were higher in the held chicks at 1, but lower at 3 days of age. Heterophil/lymphocyte ratios were higher in held females at 3 and 5 days and males at 3 days of age. Females had higher TPP levels through 5 days and hematocrits through 11 days of age. / Master of Science

Orientador: Athanase Billis / Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas / Made available in DSpace on 2018-08-17T23:58:09Z (GMT). No. of bitstreams: 1 Ribeiro_MaisaMomessodeQuintal_D.pdf: 5438814 bytes, checksum: 7ebc71e57ee2f75f13a6adb902af916a (MD5) Previous issue date: 2011 / Resumo: A capacidade de prever os tumores órgão-confinados e a recorrência bioquímica pós-prostatectomia radical é o objetivo principal dos nomogramas pré-terapêuticos. A aferição da extensão tumoral do carcinoma em biópsias transretais aumenta o valor preditivo desses nomogramas. Os objetivos deste trabalho são avaliar características anatomoclínicas dos pacientes submetidos à prostatectomia radical entre 1997 e 2008 no Hospital das Clínicas da Universidade Estadual de Campinas, associando os aspectos morfológicos encontrados nas biópsias transretais com a extensão tumoral final, a situação das margens cirúrgicas, o estádio patológico e a recorrência bioquímica. Nas biópsias, a extensão tumoral foi avaliada através das seguintes formas: 1- Número e percentagem de fragmentos comprometidos por carcinoma; 2- Extensão total e percentual de carcinoma em milímetros de todos os fragmentos e 3- Maior extensão e maior percentual de carcinoma em um único fragmento. A presença de invasão perineural, de formações glomeruloides e de micronódulos colágenos nas biópsias foram associadas a diferentes variáveis clinicopatológicas. Foram incluídas no estudo todas as prostatectomias radicais submetidas inteiramente a exame histológico e estadiadas segundo os critérios da AJCC, 7ª edição. A extensão tumoral nas prostatectomias radicais foi avaliada através do sistema de contagem de pontos. Os valores de PSA ?0,2ng/mL foram considerados como marcadores bioquímicos de progressão tumoral. Para a associação entre variáveis contínuas foi utilizado o teste de Spearman. Para a comparação entre os diferentes métodos de extensão tumoral e o estádio patológico final >T2 e a situação das margens cirúrgicas foi utilizada regressão logística binária. O tempo de sobrevida livre de doença foi estudado usando o produto limite de Kaplan-Meier. Para avaliar o risco de recorrência bioquímica, foram realizadas análises uni e multivariadas, baseadas no modelo de Cox. Foram considerados significantes os valores de p?0,05. Todos os métodos de avaliação da extensão tumoral foram capazes de prever estádio patológico final >T2 e o comprometimento das margens cirúrgicas. Com a exceção da maior extensão e do maior percentual de carcinoma num único fragmento, todos os métodos estiveram associados a um maior risco de recorrência bioquímica. Somente a percentagem de fragmentos com carcinoma (%NFC), a maior extensão tumoral num único fragmento (MFC), o comprimento total da neoplasia em milímetros (ETC) e o percentual de carcinoma em todos os fragmentos (%ETC) mostraram diferença significativa no tempo de recorrência bioquímica pós-prostatectomia radical (Kaplan-Meier). O percentual do comprimento total de carcinoma (%ETC) apresentou maior valor preditivo que as demais aferições em relação ao estádio patológico final >pT2 e à recorrência bioquímica. O número de fragmentos comprometidos por carcinoma apresentou a melhor capacidade preditiva na avaliação do comprometimento das margens cirúrgicas. Em análise multivariada, o modelo que combinou PSA pré-operatório, graduação histológica de Gleason e %ETC mostrou maior capacidade preditiva de estádio patológico >pT2 e risco de recorrência bioquímica. Os micronódulos colágenos, as formações glomeruloides e a infiltração perineural foram achados infrequentes nas biópsias (13,7%, 11,9% e 20,8%, respectivamente). Não houve associação entre a presença de micronódulos colágenos com qualquer variável clínica, patológica ou recorrência tumoral. As formações glomeruloides estiveram diretamente relacionadas com a idade dos pacientes e com a graduação histológica de Gleason, tanto nas biópsias como nas prostatectomias radicais. A invasão perineural esteve diretamente relacionada à doença extraprostática (estádio patológico >T2). Não houve associação entre invasão perineural e recorrência bioquímica pós-cirurgia. Para o anatomopatologista em sua rotina diária é menos morosa e mais prática a simples aferição do número de fragmentos com carcinoma (NFC) e o percentual em relação ao total de fragmentos da amostra (%NFC). Essas aferições, associadas ao PSA pré-operatório e à graduação histológica de Gleason, constituem um modelo preditivo significante do estádio patológico final >T2 / Abstract: The focus of pre therapeutic nomograms is to preview organ-confined prostate cancer and biochemical recurrence. Measuring cancer extent on needle prostatic biopsies enhance the predictive value of nomograms. The objectives of this study were evaluate clinical and pathological characteristics of patients submitted to radical prostatectomy at University of Campinas from 1997 to 2008, correlating the morphological aspects on prostate needle biopsy with final tumoral extent, positive surgical margins, pathological stage and biochemical recurrence. Tumor extent was evaluated on needle biopsies as: 1- Number and percentage of cores with carcinoma; 2- Total length and percentage of cancer in mm in all cores; and, 3- The greatest length and percentage of cancer in a single core. Perineural invasion, collagenous micronodules and glomeruloid structures were also observed and correlated to different clinical and pathological variables. All surgical specimens were whole-mount processed and totally embedded. The pathological stage was defined by AJCC, 7th edition. Tumoral extent was evaluated by a semiquantitative point-count method. Biochemical progression was defined as PSA ?0.2ng/mL. Logistic regression was used to relate the variables to pathological stage>T2 and surgical margins. Spearman test was used to associate continuous variables. Time to biochemical (PSA) progression-free outcome was studied using the Kaplan-Meier product-limit analysis; the comparison between the groups was done using the log-rank test. For the risk of recurrence, univariate and multivariate analyses were based on Cox model. Two-sided P value <0.05 was considered statistically significant. All measurements significantly predicted stage >pT2 and positive surgical margins. With the exception of the greatest length and percentage of cancer in a single core, all other methods were associated with a higher risk for biochemical recurrence. Only percentage of cores with carcinoma, greatest length of tumor in a single core and length and percentage of cancer in all cores significantly showed different time for PSA recurrence (Kaplan-Meier). Percentage of length of carcinoma in all cores was significantly and consistently stronger than other measures in all comparisons and combined to preoperative PSA and Gleason grade in multivariate analysis gained prediction for pathologic stage >T2 and was independent for risk of biochemical recurrence. The number of cores with carcinoma was stronger than other measures to predict positive surgical margins. Collagenous micronodules, glomeruloid structures and perineural invasion were infrequent findings on needle biopsies (13,7%, 11,9% e 20,8%, respectively). Collagenous micronodules were not related to any clinical or pathological variable, as well as tumoral recurrence. Glomeruloid structures were related to age and Gleason grade on needle biopsies and radical prostatectomies. Perineural invasion were directly associated to pathological stage >T2 (extraprostatic disease). There was no association between biochemical recurrence and perineural invasion, even in patients with organ-confined cancer. Percentage of total length of carcinoma in mm in all cores was statistically the strongest predictor of stage >pT2 and biochemical recurrence following radical prostatectomy, however, number and percentage of biopsy cores with cancer (the easiest way to measure tumor extent) are also statistically significant predictors and may be the favorite choice for the great majority of practical pathologists. Combined with preoperative PSA and Gleason grade on biopsy may improve the predictive value for stage >pT2 / Doutorado / Anatomia Patologica / Doutor em Ciências Médicas

京都大学 / 0048 / 新制・論文博士 / 博士(社会健康医学) / 乙第13004号 / 論社医博第8号 / 新制||社医||9(附属図書館) / 32932 / 京都大学大学院医学研究科社会健康医学系専攻 / (主査)教授 中山 健夫, 教授 木原 正博, 教授 黒田 知宏 / 学位規則第4条第2項該当 / Doctor of Public Health / Kyoto University / DFAM

Height, skinfold, and circumference measurements were obtained from 29 normal weight and 17 overweight (>110% of desirable weight for height) healthy pregnant women every four weeks during their second trimester of pregnancy. The mean weight gain and food intake values were not significantly different for both groups. Measurements increased at a greater rate for the normal weight gravidas than for the overweight gravidas in almost every case. For both groups, increases in fat stores were greater in the central sites than in the peripheral sites. No clear relationship between age, prepregnant weight, and weight gain during the second trimester with the birthweight of the baby was found. The infant birthweights of both groups were at an optimal level ( >2500 grams) except for one (born to the mother 151% of her desirable weight for height). The similarity in results for the two groups is greatly due to there not being a large enough difference in prepregnant weights between the two groups. Nevertheless, the results do lend support to a 20 to 30 pound weight gain for an optimal outcome of pregnancy for healthy pregnant women with a wide range of prepregnancy weights. Those women 150% or more of their desirable weight for height may need to gain on the lower end of the spectrum due to their excess endogenous reserves and to possible harm to the fetus with large gains. / Master of Science