Thèse doctorat : Chimie : Paris 12 : 2003. / Version électronique uniquement consultable au sein de l'Université Paris 12 (Intranet). Titre provenant de l'écran-titre. Notes bibliogr.

Thesis (M.S. in enviromental engineering)--Washington State University, December 2009. / Title from PDF title page (viewed on Jan. 28, 2010). "Department of Civil and Environmental Engineering." Includes bibliographical references (p. 27-31).

Thesis (M.S.)--Oregon State University, 2010. / Printout. Includes bibliographical references (leaves 78-85). Also available on the World Wide Web.

Thesis (Ph. D.)--Ohio State University, 2003. / Title from first page of PDF file. Document formatted into pages; contains xvii, 171 p.; also includes graphics (some col.). Includes abstract and vita. Advisor: Claudia Turro, Dept.of Chemistry. Includes bibliographical references (p. 168-171).

Thesis (Ph. D.)--University of Hong Kong, 1978.

Thesis (Ph. D.)--Ohio State University, 2003. / Title from first page of PDF file. Document formatted into pages; contains xiii, 155 p.: ill (some col.). Includes abstract and vita. Advisor: Tammy Bray, Nutrition Program. Includes bibliographical references (p. 139-155).

Ethanol is a widely used drug, yet an understanding of its sites and mechanisms of action remains incomplete. Among the protein targets of ethanol are glycine receptors (GlyRs). In addition to ethanol, zinc also modulates GlyR function. Although the individual effects of zinc and alcohols on GlyR function have been well studied, the combined effects of these agents have not been thoroughly examined. This project investigated the effects of zinc on alcohol action at the glycine receptor (GlyR). In Aim 1, the effects of zinc on ethanol modulation of GlyR function were tested and characterized in three GlyR [alpha] subunits ([alpha]1-3). Aim 2 explored a site of action for the augmenting effects of zinc on ethanol action at the GlyR. Mutant D80A GlyRs, which lack a zinc binding site (D80), were constructed and allowed us determine if this zinc binding site is important for the zinc/ethanol interactions that were observed in Aim 1. The effects of ethanol were reduced in mutant D80A GlyRs compared to wild type (WT). In addition, manipulating zinc levels in our buffers either by adding or chelating zinc did not change the magnitude of ethanol enhancement of mutant D80A GlyRs as it did in WT GlyRs suggesting that the D80 position is important for zinc modulation of ethanol action. Finally, Aim 3 extended the findings from Aims 1 and 2 by evaluating the effects of a GlyR point-mutation on alcohol consumption and other behavioral tests in mice. Glra1(D80A) knock-in mice provided an animal model for behavioral studies of zinc/ethanol interactions at the GlyR and showed decreased alcohol consumption and preference compared to their WT littermates. In addition, D80A KI mice had increased startle responses compared to their WT littermates. Other behavioral tests were also conducted including tests of ethanol motor incoordination and strychnine induced convulsions; there were no differences detected between KI and WT mice in these assays. Overall, our findings demonstrate that zinc is critical in determining the effects of ethanol at GlyRs and suggest that zinc signaling at the D80 position may be important for mediating the behavioral effects of ethanol action at GlyRs. / text

published_or_final_version / Physics / Doctoral / Doctor of Philosophy

As a wide band gap semiconductor, Zinc Oxide (ZnO) has recently attracted considerable attention due to its wide applicability. Transition metal (TM) doped ZnO is one of the most intensive research field in the last decade because of its possible application in spintronics devices. The Co-implanted ZnO has been considered as one of the most promising candidate in the field of diluted magnetic semiconductor (DMS). In this study, the magnetic and structural properties of Co-implanted ZnO single crystal were investigated. ZnO single crystals were implanted with 100 keV-Co ions at 300K with a fluence of 1014cm-2and subsequently annealed at 750oC and 900oC respectively. The samples were studied by secondary ion mass spectrometry, X-ray diffraction, photoluminescence, X-ray photoemission spectroscopy and vibrating sample magnetometer. The as-implanted sample seemed to be phase pure while the spinel secondary phase ZnCo2O4 was present in 750oC and 900oC samples showed trace ofCo3O4,Zn0.52Co2.48O4 and metallic Co cluster. All the samples exhibited ferromagnetism at room temperature in low field region, and the magnetic moment was found to decrease and increase after the heat treatment. In high field region, typical paramagnetism was the dominating magnetic property. More than one ferromagnetic mechanism is involved to explain the experimental results. / published_or_final_version / Physics / Master / Master of Philosophy

At the start of this project, the possible choices of metal soaps had already been narrowed to include some of the zinc soaps used in this project. These zinc soaps are mixtures of zinc stearate and zinc palmitate of varying ratios purchased from a supplier. Zinc soap was chosen as result of its common use in various industries as a lubricant and mold release, which implied potential benefits in an electrophotographic printing system. These potential benefits include, but are not limited to, a more efficient transfer from a photoconductive drum and protection of the drum from mechanical and chemical degradation. Nanoindentation of these soaps was implemented in an effort to characterize each soap mixture and compare how the soap types differed from one another. Each sample was indented under a variety of different maximum loads and at different holding times to observe effects on the modulus, hardness, and, creep. The mechanical properties measured were then used to help distinguish differences between each type and provide an insight as to how or why one mixture may be preferable over another. The data could be utilized in conjunction with further testing to be used in a simulation of an interface of interest.