Não consta resumo na publicação / Biological and immunological properties of phytohemagglutins from two brazilian varieties of beans (Phaseolus vulgaris) were studied. Through immunoprecipitation in agar gel, immuoenzymatic assays (ELISA) and eletrophoretic behavior after affinity chromatography purification it was shown that the lectins are similar. Both lectins when given to rats are toxic. They reduce growth and intestinal dissacharidase activity. They also able to smooth the \"microvillous\" of the enterocyte and to induce the appearance of autophagosomes in the enterocyte citoplasm. All this modification result in a reduced rate of carbohydrates absorption either in \"vitro\" or \"in vivo\".
| Identifer | oai:union.ndltd.org:IBICT/oai:teses.usp.br:tde-25032008-123623 |
| Date | 21 December 1982 |
| Creators | Jorge Mancini Filho |
| Contributors | Franco Maria Lajolo, Rebeca Carlota de Angelis, Joao Baptista Domingues, Paul Qualifik, Nelson de Souza |
| Publisher | Universidade de São Paulo, Ciência dos Alimentos, USP, BR |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da USP, instname:Universidade de São Paulo, instacron:USP |
| Rights | info:eu-repo/semantics/openAccess |
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