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Efeito das fito-hemaglutininas de feijões (Phaseolus vulgaris L.) sobre a mucosa intestinal / Effects of phytohemagglutinins from phaseolus beans (P. vulgaris L.) on intestinal mucosa

Não consta resumo na publicação / Biological and immunological properties of phytohemagglutins from two brazilian varieties of beans (Phaseolus vulgaris) were studied. Through immunoprecipitation in agar gel, immuoenzymatic assays (ELISA) and eletrophoretic behavior after affinity chromatography purification it was shown that the lectins are similar. Both lectins when given to rats are toxic. They reduce growth and intestinal dissacharidase activity. They also able to smooth the \"microvillous\" of the enterocyte and to induce the appearance of autophagosomes in the enterocyte citoplasm. All this modification result in a reduced rate of carbohydrates absorption either in \"vitro\" or \"in vivo\".

Identiferoai:union.ndltd.org:IBICT/oai:teses.usp.br:tde-25032008-123623
Date21 December 1982
CreatorsJorge Mancini Filho
ContributorsFranco Maria Lajolo, Rebeca Carlota de Angelis, Joao Baptista Domingues, Paul Qualifik, Nelson de Souza
PublisherUniversidade de São Paulo, Ciência dos Alimentos, USP, BR
Source SetsIBICT Brazilian ETDs
LanguagePortuguese
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis
Sourcereponame:Biblioteca Digital de Teses e Dissertações da USP, instname:Universidade de São Paulo, instacron:USP
Rightsinfo:eu-repo/semantics/openAccess

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