The prospect of the work presented in this thesis has been to engineer Cre recombinase to recognize and recombine a sequence from an HIV-1 Long Terminal Repeat (LTR), characterize the recombination proficiency of the evolved recombinase in mammalian cells and explore the potential of the recombinase for a novel antiretroviral strategy.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa.de:swb:14-1169028775210-26417 |
| Date | 17 January 2007 |
| Creators | Sarkar, Indrani |
| Contributors | Technische Universität Dresden, Biologie, Dr. Frank Buchholz, Dr. Frank Buchholz, Prof. Dr. Francis Stewart, Prof. Dr. Joachim Hauber |
| Publisher | Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | doc-type:doctoralThesis |
| Format | application/pdf |
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