Alterações do ritmo biológico no transtorno de humor bipolar

Description

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Previous issue date: 2013-09-27 / Objectives:
The
aim
of
this
report
is
to
evaluate
biological
rhythm
disruption
in
a
case-­‐
control
study
nested
in
a
population-­‐based
cross-­‐section
of
people
aged
18
to
24
years
old.
Methods:
Caseness
was
confirmed
with
the
Structured
Clinical
Interview
for
DSM-­‐IV
(SCID).
The
Biological
Rhythm
Interview
Assessment
in
Neuropsychiatry
(BRIAN)
was
used
to
measure
biological
rhythm.
The
severity
of
depressive
symptoms
was
measured
with
the
Hamilton
Depression
Rating
Scale
(HDRS),
and
to
assess
the
intensity
of
manic
symptoms
we
utilized
the
Young
Mania
Rating
Scale
(YMRS).
The
Linear
Regression
was
elaborated
to
account
for
potential
confounders.
Results:
The
sample
consisted
of
231
subjects.
Of
these,
94
were
control
subjects,
82
had
major
depression
and
55
had
bipolar
disorder
(33
type
I
and
22
type
II).
Irregular
biological
rhythm
was
associated
with
a
diagnosis
of
bipolar
disorder
(40.40±9.78;
p<0.001)
and
major
depression
(36.39±9.22;
p>0.001)
when
compared
with
healthy
controls
(27.67±6.88).
Furthermore,
the
severity
of
depression
symptoms
was
highly
correlated
with
the
total
BRIAN
scores
(r=0.592;
p>0.001).
Discussion:
This
population-­‐based
study
further
reinforces
the
notion
that
bipolar
disorder
and
major
depression
are
associated
with
impairment
in
biological
rhythm. / .

Links & Downloads

1. Faria, Augusto Duarte. Alterações do ritmo biológico no transtorno de humor bipolar. 2013. 63 f. Tese( Programa de Pos-Graduacao em Saude Comportamento) - Universidade Catolica de Pelotas, Pelotas.
2. http://tede.ucpel.edu.br:8080/jspui/handle/tede/496

Tags

MEDICINA::PSIQUIATRIA#

#-9186845475228762774#

#600

Additional Fields

Identifer	oai:union.ndltd.org:IBICT/oai:tede.ucpel.edu.br:tede/496
Date	27 September 2013
Creators	Faria, Augusto Duarte
Contributors	Jansen, Karen, Silva, Ricardo Azevedo da, Souza, Luciano Dias Mattos de, Magalhães, Pedro Vieira da Silva, Carvalho, Hudson Cristiano Wander de
Publisher	Universidade Catolica de Pelotas, Programa de Pos-Graduacao em Saude Comportamento#, #-1990782970254042025#, #600, UCPel, Brasil, Centro de Ciencias da Saude#, #-7432574962795991241#, #600
Source Sets	IBICT Brazilian ETDs
Language	Portuguese
Detected Language	English
Type	info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis
Format	application/pdf
Source	reponame:Biblioteca Digital de Teses e Dissertações do UCpel, instname:Universidade Católica de Pelotas, instacron:UCPEL
Rights	info:eu-repo/semantics/openAccess