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Previous issue date: 2012-09-14 / Introduction: Lesions hypoxic-ischemic pathologies can cause a higher or lesser degree, depending on when they occur. In postnatal insults, is the common occurrence of scarring, characterizing ulegyria and/or cysts porencephalic (U/PC).Objectives: To associate the location, extent and severity of brain injury in the spectrum U/PC, with characteristics of epilepsy, motor abnormalities and their impact on activities of daily living (ADLs).Methods: We evaluated 21 patients (15 men and 6 women, aged between 15 and 39 years, mean 25.66 SD 7.12) with epilepsy and brain injury by U/PC attending the epilepsy clinic of the Neurology Service S?o Lucas Hospital of the Catholic University of RS. All patients underwent MRI, EEG, motor and functional assessment.Results: Fifteen patients (71%) presented U, 2 (9.8%) PC and 4 (19.2%) U + PC. All EEGs were abnormal, with a predominance of slowing multilobar (66.6%) and multilobar discharges (71%). The vast number of patients (47.6%) had a combination of simple partial seizures (SPS), complex (CPS), evolving to secondarily generalized (GTS). Decreased balance and difficulty in performing activities of daily living were common to 21 patients.Conclusion: motor abnormalities resulting from brain damage, coupled with the occurrence of seizures impact the functional capacity of patients with U/PC / Introdu??o: Les?es hip?xico-isqu?micos (HI) podem causar patologias em maior ou menor grau, dependendo do momento em que estes ocorrem. Em insultos p?s-natais, ? comum a ocorr?ncia de les?es cicatriciais, caracterizando ulegiria e/ou cistos porencef?licos (U/CP).Objetivos: associar a localiza??o, extens?o e gravidade da les?o cerebral no espectro U/CP, com caracter?sticas da epilepsia, das altera??es motoras e do impacto destas em atividades de vida di?ria (AVD).M?todos: Foram avaliados 21 pacientes (15 homens e 6 mulheres, com idades entre 15 e 39 anos, m?dia de 25,66; DP = 7,12) com epilepsia e les?o cerebral por U/CP que frequentavam o ambulat?rio de epilepsia do Servi?o de Neurologia do Hospital S?o Lucas da Pontif?cia Universidade Cat?lica do RS (PUCRS). Todos realizaram RNM, EEG, avalia??o motora e funcional.Resultados: Quinze pacientes (71%) apresentaram U, dois (9,8%) CP e quatro (19,2%) U + CP. Todos os EEGs estavam alterados, com predom?nio de lentifica??o multilobar (66,6%) e descargas multilobares (71%). A maioria dos pacientes (47,6%) apresentou combina??o de crise parcial simples (CPS) e complexa (CPC), evoluindo para secundariamente generalizada (CSG). Equil?brio diminu?do e dificuldades na realiza??o de atividades de vida di?ria foram comuns aos 21 pacientes.Conclus?o: altera??es motoras, advindas de les?es cerebrais, somadas a ocorr?ncia de crises epil?pticas impactam na capacidade funcional de pacientes com U/CP
| Identifer | oai:union.ndltd.org:IBICT/oai:tede2.pucrs.br:tede/1710 |
| Date | 14 September 2012 |
| Creators | Grave, Magali Teresinha Quevedo |
| Contributors | Palmini, Andr? Luis Fernandes |
| Publisher | Pontif?cia Universidade Cat?lica do Rio Grande do Sul, Programa de P?s-Gradua??o em Medicina e Ci?ncias da Sa?de, PUCRS, BR, Faculdade de Medicina |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da PUC_RS, instname:Pontifícia Universidade Católica do Rio Grande do Sul, instacron:PUC_RS |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 7620745074616285884, 500, 600, -8624664729441623247 |
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