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Previous issue date: 2015-01-26 / Introdu??o: Obesos apresentam altera??es na fun??o pulmonar e na mec?nica
respirat?ria, entretanto, pouco se sabe em rela??o ? preval?ncia de piora da fun??o
respirat?ria quando ? considerado o aumento da adiposidade central ou perif?rica ou
obesidade geral. Objetivos: Analisar a associa??o entre fatores antropom?tricos de
adiposidade e a diminui??o da fun??o pulmonar em obesos. Materiais e M?todos:
Foram eleg?veis para o estudo indiv?duos obesos (IMC?30kg/m2
) em pr?-operat?rio de
cirurgia bari?trica e encaminhados pelo Ambulat?rio de Tratamento da Obesidade e
Doen?as Relacionadas, localizado no Hospital Universit?rio Onofre Lopes (HUOL), no
per?odo de outubro de 2005 e julho de 2014. A avalia??o incluiu informa??es clinicas e
aferi??o das medidas antropom?trica (?ndice de massa corporal (IMC), ?ndice de
adiposidade corporal (IAC) e circunfer?ncias de cintura (CC) e pesco?o (CP)) e
espirom?tricas. A preval?ncia e a an?lise por Regress?o de Poisson foi realizada
considerando as seguintes vari?veis desfecho: Capacidade Vital For?ada (CVF),
Volume Expirat?rio For?ado no primeiro segundo (VEF1) e Ventila??o Volunt?ria
M?xima (VVM), como vari?veis preditoras, se considerou: IMC, IAC, CC e CP e como
vari?veis de controle: idade, g?nero, hist?ria de tabagismo e comorbidades (diabetes
melitus, dislipidemia e hipertens?o arterial). Para a an?lise estat?stica foi utilizado
software Statistical Package for Social Science (SPSS - vers?o 20.0). Resultados:
Foram analisados 384 indiv?duos, 75% mulheres, com m?dia de IMC: 46,6 (?8,7) Kg/m2
,
de IAC: 49,26 (?9,48) %, de CC:130,84 (?16,23) cm e de CP: 42,3 (?4,6) cm. A maior
preval?ncia de CVF e VEF1 < 80% foi observada nos indiv?duos com CP acima de 42
cm, seguido daqueles com IMC acima de 45 Kg/m2
. A an?lise multivariada por
regress?o de Poisson, mostrou como fatores de risco associados ? CVF <80%, as
vari?veis: CP acima de 42 cm (odds ratio (OR) 2,41) e IMC acima de 45Kg/m2
(OR
1,71). J? para VEF1 <80% do predito, todas as vari?veis preditoras se mostraram
associadas, sendo a maior OR apresentada pela CP (3,40). A VVM n?o mostrou
associa??o com nenhuma vari?vel estudada. Conclus?o: Indiv?duos com CP acima de
42 cm apresentaram maior preval?ncia de redu??o da fun??o pulmonar e a CP foi a
medida que apresentou maior associa??o com a fun??o pulmonar reduzida nos obesos. / Introduction: Obesity shows changes in pulmonary function and respiratory
mechanics, however, little is known regarding the prevalence of worsening respiratory
function when considering the increase in central or peripheral adiposity or general
obesity. Objectives: To analyze the association between anthropometric adiposity and
decreased lung function in obese. Materials and Methods: Patients eligible for this
study obese individuals (IMC?30kg/m2) in pre-bariatric surgery and referred for
Treatment Clinic of Obesity and Related Diseases, located at the University Hospital
Onofre Lopes (HUOL), from October 2005 and July 2014. The evaluation included
clinical information and measurement of anthropometric measures (body mass index
(BMI), body fat index (BFI) and waist circumference (WC) and neck (NC)) and
spirometric. The prevalence and analysis by Poisson regression was performed
considering the following outcome variables: forced vital capacity (FVC), forced
expiratory volume in one second (FEV1) and Maximum Voluntary Ventilation (MVV)
and as predictor variables were considered: BMI, IAC, WC and NC and as control
variables: age, gender, smoking history and comorbidities (diabetes mellitus,
dyslipidemia and hypertension). Statistical analysis was performed using Statistical
Package for Social Sciences software (SPSS - version 20.0). Results: We analyzed 384
individuals, 75% women, mean BMI: 46.6 (? 8.7) kg/m2, IAC: 49.26 (? 9.48)%, WC:
130.84 (? 16.23) cm and NC: 42.3 (? 4.6) cm. The higher prevalence of FVC and FEV1
<80% was observed in individuals with NC above 42 cm, followed those with a BMI
above 45 kg/m2. Multivariate analysis using Poisson regression showed as risk factors
associated with FVC <80%, the variables: NC above 42 cm (odds ratio (OR) 2.41) and
BMI over 45Kg/m2 (OR 1.71 ). As for FEV1 <80% predicted, all predictor variables
were associated, with the largest odds presented by the NC (3.40). MVVV was not
associated with any studied varaible. Conclusion: Individuals with NC above 42 cm
had higher prevalence of reduced lung function and the NC was the measure with the
highest association with reduced lung function in obese.
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/20183 |
| Date | 26 January 2015 |
| Creators | Corte, Renata Cristina |
| Contributors | 44456042400, http://lattes.cnpq.br/4056770607573210, Guerra, Ricardo Oliveira, 39643069400, http://lattes.cnpq.br/4265185619165890, Campos, Shirley Lima, 00780302427, http://lattes.cnpq.br/3095741580780287, Bruno, Selma Sousa |
| Publisher | Universidade Federal do Rio Grande do Norte, PROGRAMA DE P?S-GRADUA??O EM FISIOTERAPIA, UFRN, Brasil |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Source | reponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN |
| Rights | info:eu-repo/semantics/openAccess |
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