1. INTRODUCTION
Ovarian cancer is now the most common gynaecological cancer and the fourth
the most common cancer among women in Lithuania. Referring to the
epidemiological research ovarian cancer has the tendency to become more
common: in 1990 there were 345 new cases of ovarian cancer and in 2004 -
already 406 new cases. In 2004 ovarian cancer morbidity was 22.2/100 000 of
inhabitants in Lithuania. Ovarian cancer is in the fifth position in the
structure of death to cancer.Since there are no specific early symptoms and
effective diagnostics of ovarian cancer so even 70 percent of diagnosed
cases were stages III or IV. After the cytoreduction surgery and adjuvant
chemotherapy with cysplatin / cyclophosphamide (CP) the survival among stage
III cases was 10-20 percent and among stage IV cases not even 10 percent. In
the structure of death to cancer ovarian cancer is in the sixth position -
16.1/100 000 of women. Since there is no effective prevention so the only
way to prolong survival of patients is to optimise the treatment.
It has been set that the optimal cytoreduction surgery could be performed
only for about 50 percent of patients with stages III or IV ovarian cancer.
As an alternative to conventional surgery for this group of patients the
neoadjuvant chemotherapy - medical cytoreduction was applied. It could lead
to the optimal conditions for cytoreduction surgery and further to
prolongation of the survival. Referring to the literature the influence of
neoadjuvant... [to full text]
| Identifer | oai:union.ndltd.org:LABT_ETD/oai:elaba.lt:LT-eLABa-0001:E.02~2005~D_20060106_093644-15138 |
| Date | 06 January 2006 |
| Creators | Simavičius, Andrius |
| Contributors | Petrauskienė, Jadvyga, Švedas, Eimantas, Didžiapetrienė, Janina, Kurtinaitis, Juozas, Pundzius, Juozas, Griciūtė, Laima, Liudvika, Nadišauskienė, Rūta Jolanta, Kaunas University of Medicine |
| Publisher | Lithuanian Academic Libraries Network (LABT), Kaunas University of Medicine |
| Source Sets | Lithuanian ETD submission system |
| Language | Lithuanian |
| Detected Language | English |
| Type | Doctoral thesis |
| Format | application/pdf |
| Source | http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2005~D_20060106_093644-15138 |
| Rights | Unrestricted |
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