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Previous issue date: 2012-01-27 / Objectives : The objective of this study was to determine the frequency, type, and severity of cerebral lesions detected by transfontanellar ultrasonography in newborns exposed to crack during gestation.Materials and methods : This was a retrospective study, involving a review of the medical records of children born to crack-using mothers who were subjected to transfontanellar ultrasonography during their first days of life.Results : Transfontanellar ultrasonography revealed abnormalities in 45/129 newborns examined (34.9%). The changes detected were: subependymal cysts in 24 infants (18.6%), lenticulostriate vasculopathy in 18 infants (14%), subependymal hemorrhage in 9 infants (7%) and choroid plexus cysts in 9 infants (7%).Conclusion : All of the abnormalities found by ultrasound examination were discrete and likely without clinical significance for the babies. However, prospective studies, with a long period of tracking, are needed to determine whether there are consequences on the neurodevelopment of children with prenatal exposure to crack that appear at a later date. / Objetivos : Determinar a freq??ncia, o tipo e a severidade de les?es cerebrais detectadas por ultrassonografia transfontanelar em rec?m-nascidos expostos ao crack durante a gesta??o.Materiais e m?todos : Este foi um estudo retrospectivo, envolvendo revis?o dos prontu?rios m?dicos de rec?m-nascidos filhos de m?es usu?rias de crack, que realizaram ultrassonografia transfontanelar nos seus primeiros dias de vida.Resultados : A ultrassonografia transfontanelar revelou anormalidades em 45/129 rec?m-nascidos examinados (34,9%). As altera??es detectadas foram: cistos subependim?rios em 24 rec?m-nascidos (18,6%), vasculopatia lenticuloestriada em 18 (14%), hemorragias subependim?rias em 9 (7%) e cistos no plexo cor?ide em 9 (7%).Conclus?o : As anormalidades ultrassonogr?ficas encontradas podem ser consideradas discretas e normalmente n?o possuem significado cl?nico para os lactentes. Por?m, estudos prospectivos, com longo seguimento, s?o necess?rios para determinar se existem consequ?ncias tardias no neurodesenvolvimento de crian?as expostas pr?-natalmente ao crack.
| Identifer | oai:union.ndltd.org:IBICT/oai:tede2.pucrs.br:tede/1392 |
| Date | 27 January 2012 |
| Creators | Lucca, Juliane |
| Contributors | Baldisserotto, Matteo |
| Publisher | Pontif?cia Universidade Cat?lica do Rio Grande do Sul, Programa de P?s-Gradua??o em Medicina/Pediatria e Sa?de da Crian?a, PUCRS, BR, Faculdade de Medicina |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da PUC_RS, instname:Pontifícia Universidade Católica do Rio Grande do Sul, instacron:PUC_RS |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 3098206005268432148, 500, 600, -8624664729441623247 |
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