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Previous issue date: 2014-03-14 / INTRODUCTION: Oral cancer is a public health problem in Brazil and around the world. Its etiology is multifactorial, tobacco and alcohol are the most important risk factors; in addition, solar radiation, HPV, diet and social conditions has been listed as risk factors for the development of this neoplasm. OBJECTIVE: This research aims to know the association between factors such as: age, sex, skin color, occupation, marital status, level of education, place of residence, use of tobacco, alcohol consumption and oral cancer in subjects attended in Reference Center for Oral Lesions, of the Brazil?s Northeast since 2002 to 2012. METHODOLOGY: This study is a case control study. The cases were formed by all population of subjects attended in this Center, with histopatologycal diagnose of oral squamous cell carcinoma, that it corresponds 127 individuals. The control group was consisted of 254 individuals from the same reference center where cases were recruited with other diseases, but without oral cancer or premalignant lesions. It considered two controls for each case. Cases and controls were adjusted by sex and age. After collecting the data it was performed univariate analysis, after the bivariate analysis (Chi Square test of Pearson) to determine the association between the dependent variable (oral cancer) and the independent variables; odds ratios (OR) and confidence interval of 95% were calculated. Finally, in the multivariate analysis was used hierarchical model with logistic regression to evaluate the interrelationships between the independent variables and oral cancer, considering the blocks of distal and proximal variables. RESULTS: The results showed that consuming more than 20 cigarettes per day [OR = 6.64; CI =2.07-21.32], high intake alcohol [OR= 3.25; CI =1.03-10.22] and the synergistic use of tobacco and alcohol [OR = 9.65; CI= 1.57-59.08] are the most important risk factors for oral cancer. CONCLUSION: The associated factors for oral cancer were smoking and drinking. Socio-demographic factors were not associated with oral cancer after adjustment for smoking and alcohol consumption. / INTRODU??O: O c?ncer de boca ? um problema de sa?de p?blica no Brasil e no mundo. Sua etiologia ? multifatorial, sendo o tabaco e o ?lcool os fatores de risco mais importantes; al?m destes, a radia??o solar, o HPV, a dieta e as condi??es sociais t?m sido elencados como fatores de risco para o desenvolvimento dessa neoplasia. OBJETIVO: Este estudo objetiva conhecer a associa??o entre fatores como: idade, sexo, cor da pele, ocupa??o, situa??o conjugal, n?vel de escolaridade, local de resid?ncia, tabagismo, etilismo e o c?ncer de boca em indiv?duos atendidos em um Centro de Refer?ncia de Les?es Bucais do Nordeste do Brasil de 2002 a 2012. METODOLOGIA: Esse ? um estudo de caso-controle. O grupo caso foi formado por toda a popula??o de indiv?duos com diagn?stico histopatol?gico de carcinoma de c?lulas escamosas de boca, que corresponde a 127 indiv?duos. O grupo controle foi composto por 254 indiv?duos do mesmo centro de refer?ncia em que os casos foram recrutados, com outras doen?as que n?o c?ncer de boca ou les?es potencialmente malignas. Considerou-se dois controles para cada caso. Casos e controles foram ajustados segundo sexo e idade. Ap?s a coleta dos dados, foram realizadas as an?lises univariada e bivariada (teste Qui Quadrado de Pearson) para verificar a associa??o entre a vari?vel dependente (c?ncer de boca) e as vari?veis independentes; foram calculadas a odds ratio (OR) e o intervalo de confian?a a 95%. Por fim, na an?lise multivariada, foi utilizado o modelo hierarquizado com regress?o log?stica para avaliar as inter-rela??es entre as vari?veis independentes e o c?ncer de boca, considerando-se os blocos de vari?veis distais e proximais. RESULTADOS: Os resultados mostraram que o consumo de mais de 20 cigarros por dia [OR= 6,64; IC= 2,07-21,32], a alta ingest?o de bebida alco?lica [OR= 3,25; IC= 1,03-10,22] e o consumo sin?rgico de tabaco e ?lcool [OR=9,65; IC= 1,57-59,08] s?o os fatores de risco mais importantes para o c?ncer de boca. CONCLUS?O: Os fatores associados para o c?ncer de boca foram tabagismo e etilismo. Fatores s?cio-demogr?ficos n?o apresentaram associa??o com o c?ncer de boca, ap?s ajuste para tabagismo e etilismo.
| Identifer | oai:union.ndltd.org:IBICT/oai:tede2.uefs.br:8080:tede/117 |
| Date | 14 March 2014 |
| Creators | Andrade, Jarielle Oliveira Mascarenhas |
| Contributors | Oliveira, M?rcio Campos |
| Publisher | Universidade Estadual de Feira de Santana, Mestrado Acad?mico em Sa?de Coletiva, UEFS, Brasil, DEPARTAMENTO DE SA?DE |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da UEFS, instname:Universidade Estadual de Feira de Santana, instacron:UEFS |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | -121975901865722803, 600, 600, 600, 8549511740116106200, -317746863433440698 |
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