Aim of the study was to evaluate the influence of clinical characteristics to the prognosis of disease and effectiveness of postoperative radiotherapy and adjuvant chemotherapy using lomustine, cisplatinum and vincristin in the treatment of children with medulloblastoma.
This study was performed 2000 – 2005 in the Kaunas University of Medicine Hospital, department of children diseases. The data of patients, treated with medulloblastoma in 1994 - 2003, were used in this study. During ten-years period in Lithuania the medulloblastoma was diagnosed for 32 children. Twenty-seven of them were included in this study.
The diagnostic tests made for the patients of the study: preoperative computer tomography or/and magnetic resonance imaging of brain; postoperative control computer tomography of brain; magnetic resonance imaging of spinal cord; bone scintigraphy with radioactive technetium; chest X-ray and ultrasound examination of the abdominal organs
The spread of the disease and size of the residual postoperative tumor separates patients of this study into two: standard and high risk groups.
Patients depending to the standard risk group were treated with radiotherapy alone. Patients included in the high risk group were treated by 2 different treatment methods: patients diagnosed with medulloblastoma between 1994 and 1998 were treated with craniospinal radiotherapy alone, other patients treated between 1999 and 2003 received radiotherapy with adjuvant chemotherapy with lomustine... [to full text]
| Identifer | oai:union.ndltd.org:LABT_ETD/oai:elaba.lt:LT-eLABa-0001:E.02~2006~D_20060925_214203-42383 |
| Date | 25 September 2006 |
| Creators | Rutkauskienė, Giedrė |
| Contributors | Bojarskas, Jurgis, Griciūtė, Liudvika Laima, Kaltenis, Petras, Griniūtė, Rasa, Kupčinskas, Limas, Juozaiytė, Elona, Usonis, Vytautas, Kaunas University of Medicine |
| Publisher | Lithuanian Academic Libraries Network (LABT), Kaunas University of Medicine |
| Source Sets | Lithuanian ETD submission system |
| Language | Lithuanian |
| Detected Language | English |
| Type | Doctoral thesis |
| Format | application/pdf |
| Source | http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2006~D_20060925_214203-42383 |
| Rights | Unrestricted |
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