The submitted publications relate to research on the epidemiology and control of diseases of importance in developing countries, and fall into two main classes. The first consists of research on methodological issues in statistics and epidemiology arising in the course of the field research. The second consists of substantive epidemiological research carried out in collaboration with scientists in developing countries over twenty years. The methodological research includes work on methods for assessing whether the change in a measured value depends on its initial value; alternative measures of diarrhoea morbidity; design issues in vaccine trials; use of the case-control study design to investigate risk factors for severe malaria; the development and validation of verbal autopsy instruments to diagnose cause of death in countries with inadequate vital resignation; studies of the bias resulting from poor methodological quality in randomised controlled trials; and use of attributable fraction methods to estimate the proportion of febrile episodes attributable to malaria and to evaluate alternative malaria case definitions. Design issues in cluster-randomised trials, particularly in the context of HIV intervention trials in developing countries, are also discussed. Among many publications on HIV infection is a key paper discussing the interaction of HIV and other sexually-transmitted disease (STDs). This argued the need for randomised trials of the impact of STD control on the HIV epidemic, and led to the first such trial in Mwanza Region, Tanzania. The Mwanza trial showed that improved STD treatment services resulted in a 40% reduction in HIV incidence in the general population, and that the intervention was highly cost-effective. This was the first randomised trial anywhere in the world to demonstrate the impact of prevention measures on HIV incidence in the general population. Other papers explore risk factors for HIV-1, HIV-2 and other STDs in a range of settings, the interaction of HIV and tuberculosis, the natural history of HIV infection, simulation models of HIV and other STDs, and the use of <i>Herpes simplex</i> virus type 2 infection as a marker of sexual risk behaviour in rural Africa.

My diploma thesis called "The Meander publishing house" characterizes this publishing house in the context of the current state of the book market and children's reading. There is a paradoxical situation in the Czech Republic. Although literary production of books for children and young people increases a lot in recent years, recent readership surveys show a significant decline in reading habits. There are several institutions in the Czech Republic trying to enforce the motivation to read and to support high-quality children's publishing. The Meander publishing house is annually involved in encouraging children to read through the festival called "Děti, čtete?" (Children, do you read?). The Meander publishing house offers the quality outstanding books which resulted in increasing of the literacy level of the Czech Republic. The publishing house is connected with the name Petr Nikl, an author, artist, theater artist and musician. He is a well-rounded Czech artist and thus he is considered to be one of the most significant personalities of Czech culture. Nikl is also very popular with readership for his literary activities in the field of nonsense prose and poetry. Powered by TCPDF (www.tcpdf.org)

Abstract Since the collapse of the Soviet Union Russia has undergone a number of reforms towards developing market economy. Accounting has encountered dramatic changes over the last two decades. Despite attractive investment opportunities in Russia, investors are often faced with uncertainty, which makes it very important to explore the quality of accounting information published in Russia. The purpose of this thesis is to investigate the quality of published accounting information in Russia. The thesis consists of four essays, each of them addressing the question of the quality of accounting information published in Russia by incorporating the specific Russian institutional environment. Special attention is paid to the role of International Financial Accounting Standards (IFRS) and foreign investors. The quality of published accounting information is conceptualized by such accounting constructs as conservatism, earnings management and value relevance. This first essay investigates the earnings quality of both listed and non-listed Russian firms and explores whether foreign ownership affects the quality of earnings published by non-listed Russian firms. The second essay examines whether emphasis on international investors is associated with the adoption of or intention to adopt IFRS in Russian firms. The third essay addresses the question of IFRS and Russian Accounting Standards (RAS) accounting quality by using the methodology proposed by Barth et al. (2008) and by value relevance constructs of accounting quality. The fourth essay investigates the value relevance of firms’ integral environmental impact, i.e. a proxy for environmental performance, following the stream of non-financial information value relevance in accounting research. This thesis provides evidence that the quality of published accounting information published in Russia depends on many factors, the most influential of these being listing on the stock exchange, IFRS and foreign investors. The results of the thesis demonstrate that the institutional characteristics of the country shape accounting numbers and influence the incentives of those preparing financial statements. The findings of the thesis include information valuable for regulators and investors.

Magister Scientiae - MSc / The completion of the Human Genome Project, a remarkable feat by any measure, has provided over three billion bases of reference nucleotides for comparative studies. The next, and perhaps more challenging step is to analyse sequence variation and relate this information to important phenotypes. Most human sequence variations are characterized by structural complexity and, are hence, associated with abnormal functional dynamics. This thesis covers the assembly of a computational platform for verifying these variations, based on accurate, published, experimental data. / South Africa

This thesis explores the growing relationship between the realms of academic knowledge production, scholarly publishing and the capitalist marketplace. Beginning with an early formulation of the goals of the modern university as understood by Immanuel Kant, I examine the extent to which these ideals, which I refer to as academic liberalism, are inadequate to account for academic practices today. Despite several theoretical attempts to justify the autonomy of academic practice, I demonstrate how a contemporary account of academic practice must reconsider it s socio-economic situation. I follow a sociology of knowledge methodology to examine the extent to which our current political economic situation leads to economic crises in academia. Among the more significant of these crises, I argue, is the “crisis of consumption” for academic libraries. In this crisis lies one of the connections of scholarship to the logic and practices of contemporary capitalism. With the loss of academic knowledge's primary consumer, a chain reaction is set off throughout the system of scholarly production where scholarly publishers must scramble for new markets in order to maintain their already modest print runs. Through interviews and institutional ethnographic data, I demonstrate the extent to which the consumer is considered as a factor in the publication of scholarly knowledge. An engagement of scholarship with consumer culture also brings about many significant changes for the academic author. Using the cultural Marxist theories of Jean Baudrillard and Pierre Bourdieu, I examine how publishing in consumer culture leads to a variety of forms of commodification for the academic author. Ultimately, I demonstrate that economic forces penetrate the very practices that are traditionally thought to exist outside of economic determination. / Arts, Faculty of / Anthropology, Department of / Graduate

There are many different doorways into the world of book publishing and it can be challenging, but there are choices that can make it easier. Aspiring publishers often have a hard time breaking into this world because they have no guide. This thesis will be a guide to traversing the different avenues into the world of publishing. Prospective publishers, editors, and writers will be provided with a landscape of what it’s like to work in book publishing. It will also cover the two different ways that people become publishers, an overview of the basic requirements that publishing houses look for in potential employees, and the basic process of what publishers do.

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No description available.

"In view of his success in making notable contributions to the literature of America, this writer wondered as to why Carey, apparently an important contributor of his age, had received so little credit among the historians of American culture. This perplexity gave rise to this paper in which his contributions as an editor, publisher, and bookseller are being examined. In so doing his position among his contemporaries is being studied to ascertain his proper place among the leaders in the periodical world, and to discover when writers to whom he gave a helping hand lived through the years, why Carey, who encouraged them, published their works even though financial returns were very uncertain, and introduced them to the American public, fails to receive proper recognition"--Introduction. / Typescript. / "August, 1952." / "Submitted to the Graduate Council of Florida State University in partial fulfillment of the requirements for the degree of Master of Arts." / Advisor: Robert G. Clapp, Professor Directing Paper. / Includes bibliographical references (leaves 42-43).

With the increasingly high speed of the Internet and its wide spread usage, the current Internet architecture exhibits some problems. The publish/subscribe paradigm has been developed to support one of the most common patterns of communication. It makes “information” the center of communication and removes the “location-identity split” (i.e., that objects are at specific locations to which you must communicate with to access the object). In this thesis project a publish/subscribe network is built and then used in the design, implementation, and evaluation of a publish/subscribe proxy for today’s HTTP based communication. By using this proxy users are able to use their existing web browser to send both HTTP requests and Publish/Subscribe Internet Routing Paradigm (PSIRP) requests. A publish/subscribe overlay is responsible for maintaining PSIRP contents. The proxy enables web browser clients to benefit from the publish/subscribe network, without requiring them to change their behavior or even be aware of the fact that the content that they want to access is being provided via the publish/subscribe overlay. The use of the overlay enables a user’s request to be satisfied by any copy of the content, potentially decreasing latency, reducing backbone network traffic, and reducing the load on the original content server. One of the aims of this thesis is to make more PSIRP content available, this is done by introducing a proxy who handles both HTTP and PSIRP requests, but having received content as a result of an HTTP response it publishes this data as PSIRP accessible content. The purpose is to foster the introduction and spread of content based access. / Med allt högre Internetshastighet och dess utbredda användning, uppvisar den aktuella Internet-arkitekturen vissa problem. Publicera / prenumerera paradigm har utvecklats för att stödja en av de vanligaste mönstren för kommunikation. Det gör att "information" blir centrum av kommunikation och tar bort "plats-identitet split" (dvs att objekten är på specifika platser som du måste kommunicera med för att komma åt objektet). i detta examensarbete byggs ett publicera / prenumerera nätverk och sedan används i utformningen, genomförandet, och utvärdering av en publicera / prenumerera proxy för dagens HTTP-baserad kommunikation. Genom att använda denna proxy kan användare kan använda sin befintliga webbläsare för att skicka både HTTP-förfrågningar och publicera / Prenumerera Internet Routing Paradigm (PSIRP) begäran. En publicera / prenumerera överlagring är ansvarig för att upprätthålla innehåll av PSIRP. Fullmakten gör det möjligt för klienter av webbläsare att dra nytta av publicera / prenumerera nätverket, utan att kräva dem att ändra sitt beteende eller ens vara medvetna om det faktum att det innehållet som de vill komma åt tillhandahålls via publicera / prenumerera överlägg. Användningen av överlägget kan en användare begäran som skall uppfyllas av en kopia av innehållet, eventuellt minskande latens, vilket minskar trafiken stamnät, och minska belastningen på det ursprungliga innehållet servern. Ett av syftena med denna uppsats är att göra mer PSIRP innehåll tillgängligt och detta görs genom att införa en proxy som hanterar både HTTP och PSIRP förfrågningar, men har fått innehåll som en följd av en HTTP-svar offentliggörs denna data som PSIRP tillgängligt innehåll. Syftet är att främja införandet och innehållbaserade åtkomsten.