The past century has seen striking changes in family formation in Ireland. Family dynamics are fundamental aspects of social change, but they have been neglected by social research in Ireland since the 1970s. This thesis draws on already available national data to study movements into marriage and parenthood in detail and thereby improve our understanding of family dynamics. The research focuses, in the main, on the 1926 to 1991 census period; a period characterised by the transition from high rates of nonmarriage and large family sizes to more standard European levels. The study primarily addresses the class dimension of family formation. Social class remains a strong predictor of marriage and fertility patterns. The study first maps the long-standing trend of higher rates of non-marriage and higher rates of marital fertility in the poorer sections of Irish society. The fertility levels of the class categories experiencing economic marginalisation have remained high so that the burden of dependency is heaviest among working class and farming families. Fertility decline was, however, evident in all socio-economic groups. Secondly, the thesis provides the first serious examination of quantitative evidence to assess the hypothesis that high rates of marital fertility act as a marriage deterrent. Despite the availability of more effective fertility controls, marriage plans continue to be influenced by the size of the prospective family. The results highlight the importance of economic resources as a prerequisite to marriage. Economic rationality is not, however, the only driving force. Thirdly, the thesis investigates the degree to which changes in family formation were related to changes in the composition of Irish society. A standardisation exercise isolating the effects of population structure revealed that class compositional changes cannot account for changes in male fertility rates over the course of the twentieth century but, were important in understanding declining rates of celibacy.

Infertility affects ~20% of couples in Europe and in 50% of cases the problem lies with the male. The development of assisted reproductive technologies (ART) such as in vitro fertilisation (IVF) and intra-cytoplasmic spermatozoa injection (ICSI) has allowed some couples to overcome male-factor infertility. However concerns remain over the increasing use of ART as elevated levels of DNA damage in sperm from infertile men have been reported and a link between DNA damage in sperm and early embryonic failure has been demonstrated. DNA damage in sperm, caused by oxidative stress may also be passed on from father to child resulting in an increased incidence of childhood cancer. This has led to fears that the use of damaged sperm in ART could contribute to early embryonic failure and/or birth defects. The studies described in this thesis used mouse models to investigate the relationship between DNA integrity in male germ cells and male fertility. This was achieved by studying both the effects of targeted ablation of genes involved in DNA repair and the impact of scrotal heat stress on testicular function and sperm DNA integrity. Three lines of transgenic mice with deletions in genes involved in genomic integrity (Ercc1, Msh2 and p53) were studied. All three genes are expressed in the testis. These studies confirmed and extended studies on Ercc1 knockout (-/-) mice showing reduced germ cell complement, increased apopotosis, an increased percentage of damaged sperm and demonstrated for the first time that depletion of Ercc1 results in an increased incidence of unrepaired double strand DNA breaks (DSB) in pachytene spermatocytes. The persistence of DSBs in spermatocytes and abnormal sperm chromatin structure confirmed that the repair functions of Ercc1 are essential for normal germ cell maturation. In the p53-/- mice these studies showed for the first time that there was an increase in DSBs in spermatocytes and an increase in numbers of sperm with damaged DNA. The level of apoptosis was also increased in the testes suggesting that caspase-3 mediated apoptosis is not entirely p53 dependent as been previously suggested. These studies demonstrated for the first time that targeted ablation of Msh2 compromises germ cell complement and as in the Ercc1-/- this resulted in gaps in the seminiferous epithelium consistent with clonal loss of germ cells. Consistent with a role for MSH2 in mismatch repair no DSBs were detected in spermatocytes from Msh2-/-. Testicular function is temperature dependant and due to their location in the scrotum testes are normally kept between 2ºC and 8ºC below core body temperature. In mice transient scrotal heat stress (30 minutes at 38°C, 40°C and 42°C) disrupted testicular function. Analysis of sperm and testis parameters revealed that stress at 38°C was sufficient to have subtle effects on epididymal function but the higher temperatures had additional consequences for testicular function which resulted in DNA damage in spermatocytes, germ cells loss and increased apoptosis. Further studies into the pathways of apoptosis demonstrated that the mitochondrial/intrinsic pathway plays a role in heat stress response. The fertility of males was altered in those heated to 42°C resulting in reduced pregnancy rate and litter size. Given that the paternal genome is reported to be required for the development of extraembryonic tissues and this will influence growth of the embryo, it was interesting to note an increase in resorption sites in pregnancies using 40°C males. IVF was used to demonstrate that embryos formed using sperm from males stressed at 42°C were compromised between the 4-cell and blastocyst stage suggesting that though sperm with DNA damage are still capable of fertilisation, the paternal DNA was introducing genomic instability to the embryo and having fatal effects on development. These studies have also shown that one possible underlying cause of the disturbance in testicular function is hypoxia, as a marked increase in Hif1 alpha (a marker of hypoxia) mRNA and relocalisation of the protein was observed in the testis. In conclusion, DNA damage in the male germ line caused either by induced stress, or by targeted ablation of DNA repair genes, can disrupt testicular architecture, function and therefore the fertility of mice. These data have demonstrated that deletion of Ercc1, Msh2 and p53 can have differential but overlapping affects on germ cell function and sperm production and that increased scrotal temperature can cause subfertility in male mice. This study has provided further confirmation of possible male-mediated effects on embryo survival and these findings should be taken into consideration when using sperm from infertile men in IVF/ICSI treatments where the normal quality control processes involved in fertilisation are bypassed.

Soil organic matter (SOM) models simplify the complex turnover dynamics of organic matter in soils. Stabilization mechanisms are currently thought to play a dominant role in SOM turnover but they are not explicitly accounted for in most SOM models. One study addresses the implementation of an approach to account for the stabilization mechanism of physical protection in the SOC model RothC using 13C abundance measurements in conjunction with soil size fractionation data. SOM models are increasingly used to support policy decisions on carbon (C) mitigation and credibility of model predictions move into the focus of research. A site scale, Monte Carlo based model uncertainty analysis of a SOM model was carried out. One of the major results was that uncertainty and factor importance depend on the combination of external drivers. A different approach was used with the SOM ECOSSE model to estimate uncertainties in soil organic carbon (SOC) stock changes of mineral and organic soils in Scotland. The average statistical model error from site scale evaluation was transferred to regional scale uncertainty to give an indication of the uncertainty in national scale predictions. National scale simulations were carried out subsequently to quantify SOC stock changes differentiating between organic and mineral soils and land use change types. Organic soils turned out to be most vulnerable to SOC losses in the last decades. The final study of this thesis emplyed the RothC model to simulate possible futures of global SOC stock changes under land use change and ten different climate scenarios. Land use change turned out to be of minor importance. The regionally balance between soil C inputs and decomposition leads to a diverse map of regional C gains and losses with different degrees of certainty.

Differentiation of marital and reproductive behavior in East Kazakhstan Abstract This study primarily addresses nuptiality and fertility patterns among youth in East Kazakhstan region. The data are obtained from censuses, vital statistics and survey "Marital and reproductive behavior of young women in Ust-Kamenogorsk". The survey data collection has been supported by Center of International programs of Kazakhstan "Bolashak" and Charles University in Prague. The aim of the thesis is to study marital and reproductive behavior in East Kazakhstan region, in particular, differentials by sex, age, nationality and place of residence. Nuptiality and fertility rates have increased in the region during the study period. Hence, the impact of external socio-economic factors on marital and reproductive behavior of population was analyzed. Keywords: Nuptiality, Marriage, Divorce, Fertility, Kazakhstan, East Kazakhstan region, Ust- Kamenogorsk, Youth

Master of Science / Department of Animal Sciences and Industry / Jeffrey S. Stevenson / The objectives were to evaluate the effects of equine chorionic gonadotropin (eCG) administration on preovulatory follicle diameter, serum estradiol and progesterone concentration, corpus luteum (CL) diameter, estrual activity, and pregnancy rate. Lactating dairy cows were submitted to a Presynch-Ovsynch timed artificial insemination (TAI) protocol. Cows (n = 121) in a single herd were treated with 2 injections of prostaglandin F2α (PGF) 14 d apart (Presynch), with the second injection administered 11 d before the onset of a timed AI protocol (Ovsynch; injection of GnRH 7 d before and 56 h after PGF2α, with TAI administered 16 to 18 h after the second GnRH injection). Cows were assigned randomly to receive either saline or 400 IU eCG concurrent with the PGF2α injection of the Ovsynch protocol (d 0). Blood samples were collected during the study to monitor serum changes in progesterone and estradiol to determine if eCG would facilitate increased estrual activity, improved ovulatory response to GnRH, and enhanced post-ovulatory luteal function. Administration of eCG tended to increase the number of CL and on d 9 and 16 after PGF2α, corresponding to d 6 and 13 post-ovulation. Volume of the post-eCG treatment luteal tissue was increased only on d 16. Timed AI pregnancy rates did not differ between eCG (36.9%) and control cows (41.8%). We concluded that use of eCG provided no profertility advantages to dairy cattle when programmed for a timed insemination at first service.

faculty of Humanities School of Social sciences 0411881k muanzu@yahoo.fr / Previous studies on fertility in South Africa have mostly focused on the analysis of fertility trends, levels and differentials at the national level and have argued that socioeconomic development affects the national fertility level. This study examines the fertility levels in South Africa informal settlements with a view of examining whether there is any fertility variation between national and informal settlements. Data from the South Africa 2001 Census 10 per cent sample were used. Three levels of analysis were conducted. One examines fertility differentials. Two, multiple regression technique was applied to identify important socioeconomic factors of fertility in South African informal settlements and finally direct and indirect estimation of fertility was done. There is no difference in fertility levels between national and informal settlements. Fertility of 3 children per woman, in informal settlements is close to the national figure of 2.9. It is also shown that there is an inverse relationship between fertility and education and income, in South Africa informal settlements. Multivariate analysis shows that only about 6% of the variation in the dependent variable can be explained by the socioeconomic factors considered in the study. Fertility in the informal settlements was highest amongst women with higher education, among married women, and among those unemployed. In addition, the fertility of Christian women, and those women dwelling in households without radio and television was high. It is found that there is no difference between fertility levels at the national and informal settlements levels.

Lai Tak Chi. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2000. / Includes bibliographical references (leaves 69-72). / Abstracts in English and Chinese. / Acknowledgments --- p.ii / English Abstract --- p.iii / Chinese Abstract --- p.iv / Table of Contents --- p.v / List of Tables --- p.vii / List of Figures --- p.viii / List of Appendices --- p.ix / Chapter Chapter 1. --- Introduction --- p.1 / Chapter Chapter 2. --- Literature Reviews --- p.8 / Chapter 2.1 --- Theoretical Approach of Household Fertility Decision --- p.8 / Chapter 2.2 --- Modeling of Household Fertility Decision --- p.17 / Chapter 2.2a. --- Linear Regression Model --- p.17 / Chapter 2.2b. --- Count Data Models --- p.18 / Chapter 2.2c. --- Goodness of Fit --- p.23 / Chapter 2.3 --- Summary and Limitations --- p.25 / Chapter Chapter 3. --- Data Sources and Limitations --- p.26 / Chapter 3.1 --- Data Sources of the Cross-Section Analysis --- p.26 / Chapter 3.2 --- Data Sources of the Time-Series Analysis --- p.26 / Chapter 3.3 --- Data Limitations of the Cross-Section Analysis --- p.27 / Chapter 3.4 --- Data Limitations of the Time-Series Analysis --- p.27 / Chapter Chapter 4. --- Decision of Birth --- p.29 / Chapter 4.1 --- Variable Definitions and Explanations --- p.29 / Chapter 4.2 --- Statistical Framework --- p.33 / Chapter 4.3 --- Results and Explanations for the Regression of the Decision of Birth --- p.33 / Chapter 4.4 --- Summary --- p.36 / Chapter Chapter 5. --- Fertility Behavior --- p.38 / Chapter 5.1 --- Variable Definitions and Explanations --- p.38 / Chapter 5.2 --- Statistical Framework --- p.40 / Chapter 5.3 --- Empirical Results --- p.42 / Chapter 5.4 --- Summary --- p.54 / Chapter Chapter 6. --- Time Series Analysis --- p.56 / Chapter Chapter 7. --- Conclusions --- p.63 / Appendices --- p.65 / Bibliography --- p.69

The anticipated risk of job loss and material insecurity are related to fertility postponement in the same way as unemployment is. Given the sequential nature of fertility and occupational decisions, unfavorable working conditions should be resolved before having children, and result in an increase in people's assignment of importance to paid work when developing their childbearing plans. We aim to demonstrate this link, focusing on perceived employment and material insecurity, the importance assigned to paid work in forming fertility intentions, the construction of fertility intentions, and their realization. Using two waves of the Austrian Generations and Gender Survey, we apply probit regressions to analyze gender variations in the associations between uncertainty conditions, the importance of paid work, fertility intentions and behavior. Results reveal that work and related benefi ts become salient when they are insecure, and that material insecurity among men discourages childbearing. For women, we find support for the hypothesis that the anticipated risk of job loss inhibits the realization of fertility intentions - intentions which are less likely to be constructed under such conditions from the onset of family planning processes.

Vita. / Digitized by Kansas Correctional Industries

In the context of population ageing and its consequences for future welfare state support, the issue of low fertility in Europe has become very topical over the past two decades. The role of policy and gender equality in explaining fertility behaviour has gained a prominent position in the literature and even today represents two streams that are believed to be important predictors of the current fertility outcomes in Europe. When building arguments regarding the policy effects on fertility behaviour, authors often implicitly assume that everyone living in a given country is entitled to support from particular statutory policy and/or that each individual is entitled to the same amount of support. However, although everyone of reproductive age is likely to make a decision about having children, the policy support does not mean the same thing for each one of them. Instead the set of rules on eligibility conditions clearly states who is entitled to welfare state support and how extensive this support is going to be. These rules consequently mediate the impact a child is going to have on an individual’s circumstances and therefore may influence the decision of whether or when to start a family and how big this family is going to be. The issue of within-country variation in the distribution of entitlements to policy support has been largely ignored in the comparative welfare state literature and has not been sufficiently acknowledged in fertility research. By focusing on the birth-related leave schemes in Europe, this thesis aims to address this gap. It does so by linking the individual-level survey data from EU-SILC with legislative rules from 27 European countries. Such an approach allows the identification of individuals that would be entitled to birth-related leave and compares how their socio-economic situation would change if they were to have a child. Apart from that the thesis is set into a wider context of contemporary fertility research that examines the role of gender issues in fertility behaviour. As such the thesis is particularly interested in the distribution of entitlements to birth-related leave between men and women and in the analyses pays special attention to the policy designs that strengthen traditional gender roles and whether they are associated with fertility behaviour.