Objectifs: Malgré beaucoup de progrès dans la gestion médico-électrique, certains problèmes demeurent et plusieurs patients souffrant d'insuffisance cardiaque sont encore dans l'impasse. Ainsi, les dispositifs d'assistance ventriculaire gauche (LVAD) ont été développés pour réduire les conséquences de l'insuffisance cardiaque et améliorer la qualité de vie. Malgré les avantages évidents, plusieurs complications : thrombo-embolie, infection dû au câble d'alimentation externe, dépendance aux batteries demeurent. L'ICOMS est un nouveau concept de LVAD mélangeant une pompe entièrement intraventriculaire, synchronisé avec le cœur et relié à une batterie interne. Méthodes et résultats : L'intervalle de fonctionnement prévu est un débit de 0.8 to 6.7 10-5 m3/s à une vitesse de rotation de 733 to 942 rad/s, avec des pressions physiologiques. Le point de fonctionnement choisi pour la conception est un débit de 3.3 10-5 m3/s et 10.6 103 Pa . Dans cette étude, Une simulation numérique est réalisée avec des profils de lames différents pour chaque région de fluide étudié. Les performances telles que l'efficacité, la contrainte de cisaillement sont analysée pour vérifier l'efficacité pour les patients atteints d'insuffisance cardiaque. Afin d'obtenir le meilleur résultat avec le logiciel ANSYS, le modèle k-ε turbulent a été appliquée pour obtenir des caractéristiques d'écoulement entre l'entrée et à la sortie de l'évacuateur du redresseur de la pompe. Les résultats numériques montrent une performance acceptable pour les adultes pour délivrer des pressions physiologiques avec une efficacité hydraulique de 10 à 37% ainsi qu'un niveau acceptable de stress de cisaillement maximale le long de la surface de la partie mobile de la pompe. La deuxième partie de l'étude est une étude expérimentale où un prototype a été testé sur banc d'essai. Les résultats ont montré que la pompe pourrait fonctionner et améliorer le débit cardiaque de 1.7 à 6.7 10-5 m3/s. Les résultats in vitro convergent vers les résultats numériques. Pour les tests in vivo, 6 moutons ont été opérés pour l'implantation du LVAD. L'ICOMS a été implanté dans l'apex du ventricule gauche. Plusieurs paramètres hémodynamiques et échocardiographiques ont été stockés dans des conditions normales ou pathologiques. Conclusion: Nous avons montré que l'ICOMS pourrait présenter un effet potentiel pour réduire les conséquences de l'insuffisance cardiaque. De nouvelles expérimentations sont nécessaires pour confirmer notre résultat et optimiser ce nouveau LVAD / Objectives: Despite much progress in medical-electrical management, some problems remain and several heart failure patients are still in a no option solution. In this way, artificial hearts as Left Ventricular Assist Device (LVAD) have been developed. Despite evident benefits, several complications as thromboembolism, driveline infection, batteries dependency remain. ICOMS is a new LVAD concept mixing a fully intraventricular pump, heat rate-synchronized and connected with intracorporeal batteries. Methods and Results : It is expected to deliver 0.8 to 6.7 10-5 m3/s at rotational speeds of 733 to 942 rad/s over physiologic pressures and has a selected design point of 3.3 10-5 m3/s and 10.6 103 Pa . In this study, the axial blood pump with motor connected to impeller has been selected to numerical simulation. This selection is based on axial flow pump with different blade profile for each fluid region and studied on its performance such as efficiency, wall shear stress and considering effective operation for cardiac failure patients. In order to achieve the best result with the ANSYS software, k-ε turbulent model has been applied to obtain the flow characteristics from inducer inlet to straightener outlet of the pump. Numerical results show acceptable performance to deliver physiologic pressures with hydraulic efficiency of 10 to 37 % as well as acceptable maximum shear stress level along the blade tip surface of the impeller. The second part of the study is an experimental investigation where a prototype device was tested in a test bench circulation loop have shown that the pump could operate and improve the cardiac output of 1.7 to 6.7 10-5 m3/s. In vitro results converge to numerical results. For test vivo 6 sheep were operated for the LVAD implantation with the support of cardiopulmonary by-pass. The ICOMS was implanted into the LV apex. Several hemodynamic and echocardiographic parameters were stored as well as in normal or pathological conditions and analyzed. Conclusion: We showed that the ICOMS could present a potential effect in the LV support reducing the heart failure criteria. As evidence, further experimentations are necessary to confirm our result and to optimize this new LVAD

The objective of the present thesis research is to apply state-of-the-art experimental and data analysis techniques to the study of gas-liquid pipe flows, with a focus on conditions occurring in header-feeder systems of nuclear reactors under different accident scenarios. Novel experimental techniques have been proposed for the identification of the flow regime and measurement of the flow rates of both phases in gas-liquid flows. These techniques were automated, non-intrusive and economical, which ensured that their use would be feasible in industrial as well as laboratory settings. Measurements of differential pressure and the gas and liquid flow rates were collected in vertical upwards air-water flow at near-atmospheric pressure. It was demonstrated that the probability density function of the normalized differential pressure was indicative of the flow regime and using non-linear dimensionality reduction (the Elastic Maps Algorithm), it was possible to automate the process of identifying the flow regime from the differential pressure signal. The relationship between the probability density function and the power spectral density of normalized differential pressure with the gas and liquid flow rates in air-water pipe flow was also established and a machine learning algorithm (using Independent Component Analysis and Artificial Neural Networks) was proposed for the estimation of the phase flow rates from these properties. The proposed methods were adapted for use with single and dual conductivity wire-mesh sensors in vertical upwards and downwards air--water flows. A thorough evaluation of the performance and measurement uncertainty of wire-mesh sensors in gas-liquid flows was also performed. Lastly, measurements of the flow distribution in feeder tubes supplied with air-water mixtures by a simplified header model were collected and correlated to the observed flow patterns in the header.

Cette thèse de doctorat porte sur l'étude et la réalisation d'une plateforme de pesage dynamique pour véhicule roulant basée sur un concept d'intégration de la charge. Ce concept est mis en œuvre en vue de pouvoir minimiser la taille et l'encombrement de ce type de dispositif tout en effectuant des pesées présentant des caractéristiques métrologiques acceptables. Nous démontrons tout d'abord au travers de la réalisation d'un prototype et de plusieurs campagnes d'essais, la faisabilité de la méthode utilisée. Nous évaluons dans un deuxième temps les performances présentées par le prototype lors du pesage de véhicules légers roulant jusqu'à des vitesses de 35km/h. Une étude est ensuite menée sur les jauges de déformation piézorésistives et les jauges piézoélectriques réalisées en couches épaisses grâce à des techniques de sérigraphie. Nous caractérisons ces transducteurs avec pour objectif leur utilisation dans des dispositifs de pesage en remplacement des jauges de déformation classiques à filaments métalliques. / This PhD thesis is devoted to the study and implementation of a weigh-in-motion platform for vehicle based on a concept of integration of load. This concept is used to minimize the size of this kind of device while performing weighings with acceptable results. First, we show thanks to a protoype and several test campagns, the feasability of the method used. In a second time, we evaluate the performances of the prototype in terms of precision and repeatability with the dynamic weighing of vehicles at speeds up to 35km/h. A study is finally conducted on thick-film piezoresitive strain gauges and piezoelectric gauges manufacturing by a screen-printing process with cermet and polymer pastes. We characterize these tranducers with the goal of used them as an alternative of conventional foil strain gauges.

Volatile and semi-volatile organic compounds are ubiquitous, and some of them are hazardous. The ability to rapidly detect and identify trace levels of them in air has become increasingly important. The conventional device used today for sampling and concentrating them in air is thermal desorption tubes filled with specific sorbents, which can only collect air samples at flow rates of 100-200 mL/min. In order to detect low concentration (ppt level) VOC compounds, long sampling time (>2 h) and sensitive detection are required. At the same time, portable instrumentation for on-site analysis has been developing rapidly. The somewhat lower performance of portable instruments compared to benchtop systems requires the sampling of even greater sample volume in order to reach the same detection limits. In this study, two high flow rate air sampling devices, i.e., a multi-capillary trap and a concentric packed trap, were developed to sample a large volume of air in a short time period. The multi-capillary trap was constructed by bundling analytical capillary gas chromatography columns together in parallel. As low as single digit ppt detection limits were reached in less than 25 min with this trap, and as high as 8.0 L/min flow rate was sampled. The simple and compact multi-capillary trap could be easily used with a conventional thermal desorption system to perform high flow rate sampling. A concentric packed high flow rate trap was also developed by packing sorbent layers concentrically around an empty tube. The concentric packed trap achieved a high flow rate (>10 L/min) because it had a high surface area and short sorbent bed. Also, its large sorbent amount (>1 g) provided large breakthrough volume (>100 L) required to achieve low detection limits. An equilibrium distribution sampling system was developed by absorbing selected analytes in granular PDMS to provide calibration for on-site instrumentation. Furthermore, a needle trap device was coupled in tandem to both high flow rate air samplers to perform second-stage concentration of VOCs down to the ppt level. Concentration factors of 104 to 105 were achieved within 30 min using both systems, i.e., over 10 to 100 times more sample was collected compared to conventional TD systems.

The aim of the project was to get familiar with the environment of ANSYS CFX, create several models of fans and synchronous machine model in Autodesk inventor, create model of cooling medium flow through the machine with these fans and evaluation of results. Firstly the thesis describes the synchronous machine itself, losses of the machine, the flow of power of synchronous machine and methods of its cooling. Next the thesis describes each kind of heat transfer, laminar and turbulent flow. The thesis also refers of kind of the fans and the program used to calculate the flow Ansys CFX, including the method that Ansys used to calculate. The work describes the individual modification of fans and setting of calculation in ANSYS. Then displays the results of the analysis these fans for different numbers of fan blades and for modification of the fan. Then the thesis analyzes selected modifications due to changing speed. In the last chapter shows the analysis of flow in the machine with three different fans. In particular, there is shown the mass flow rate, pressure and its distribution on areas for evaluation.

Master´s thesis is focused on measurement uncertainty problems, particularly on the uncertainty determination and then on the practical application. The thesis is divided into three parts. A theoretical part deals with issues concerning uncertainties on the theoretical level, transition from the measurement error to the measurement uncertainty. This part also clarifies the basic terms concerning this issues based on “ČSN ISO 5168” standard and another legislative materials. The other part is focused on temperature regulations by thermostatic heads and valves. This part also handles thermostatic heads and valves history, division, generally use and legislative background represented by standard „EN 215“. Practical part follows previous sections. I am determining the measure uncertainty of thermostatic heads and valves flow characteristic determining device. All the results and knowledge obtained are given in the conclusion of the thesis.

The control of non-metallic inclusions is very important for the improvement of performance during the application of tool steel. This present study was performed to see the effect of changing of some process parameters during the vacuum degassing of the melt and how these changing parameters affects the characteristics of inclusions in tool steel. The main parameters that were changed during the vacuum degassing were the change of induction stirring, argon flow rate from both the plug 1 and 2 and different ladle ages for different heat. Electrolytic extraction method was used to observe the morphology and characteristics of inclusions as a 3 dimensional view in tool steel. Four lollipop samples from four different heats were used for the experiment and all the samples were after vacuum (AV) degassing. In this study four different types of inclusions were found and they are classified as type 1, 2, 3 and 4. Of them type 1 inclusion was the major one with mostly spherical shaped. This study shows that among the three parameters, induction stirring has the biggest effect for the total number of inclusions per volume in the sample than the other two parameters Heat 4A showed the lowest number of inclusions per volume comparing with the other heats. The main reason behind this can be said that the induction stirring was the lowest comparing with the other heats with moderate argon flow and ladle age of 12. Extreme value analysis was used in this study to predict the probability of getting largest size inclusions in a certain volume of the metal. For the prediction of the largest inclusion size, both the electrolytic extraction (3D) and cross-sectional (2D) method was used. Later in this study comparison was done to determine the accuracy of both the methods and it is concluded that for the type 1 inclusions electrolytic extraction method shows almost similar trend with cross-sectional method and electrolytic extraction method shows better accuracy for the prediction of largest size inclusions than the cross-sectional method. Electrolytic Extraction method is also applicable for the prediction of largest size inclusions for multiple types of inclusions.

An accurate satellite attitude and orbit control is a key factor for a successful mission. It guarantees for example sun acquisition on solar panels, fine pointing for optimal telescope usage or satellite lifting to reach higher orbits, when required. Furthermore attitude and orbit control is applied to compensate any occurring disturbances within the space environment. The problem tackled in the present thesis is the optimization of thruster commanding to perform spacecraft orbital manoeuvres. The main objective is to develop different algorithms that are suitable for on-board implementation and to compare their performance. For an optimal thruster command distribution the algorithms shall solve linear programming (or optimization) problems, more exact they shall compute thruster on-times to generate desired torques and/or forces, which are requested by the on-board software. In total three different algorithms are developed of which the first one is based on the pseudoinverse of a matrix, the second one is a variation of the Simplex method and the third one is based on Karmarkar’s algorithm, which belongs to the interior-point methods. The last two methods are well known procedures to solve linear programming problems and in theory they have been analyzed before. However this paper proves their practical application and industrial feasibility for orbital manoeuvres of the weather satellites of ESA’s MTG project and their scalability to any number of thrusters on a generic satellite for 6 degrees of freedom manoeuvres. There are 6 MTG satellites and each has 16 one-sided reaction control thrusters, placed at specific positions and pointed towards defined directions. Physical mechanisms limit the thrusters output to minimum on- and off-times. The focus of this thesis will be on the orbital transfer mode, due to the high disturbances that arise during four motor firing sessions at the apogee, executed to reach higher orbits and finally GEO. The firing sessions are performed by a liquid apogee engine and while this engine is in boost mode, the thrusters shall be used for attitude control only. The technique (nominal case) developed by OHB for this maneuver and currently operational uses 4 thrusters only, which are all pointing in the engine’s direction. They are also used to settle the fuel before the engine is turned on. For control the Pseudoinverse method is applied. If one of the 4 thrusters fails, the backup scenario takes place, which includes using 4 totally different thrusters and no fuel settling, due to their unfavorable position with respect to the engine. The initial idea of this work was to develop a controller for 6 thrusters, using only 2 of the 4 nominal case thrusters, to have a better control performance in the backup case. The Pseudoinverse method was developed by OHB before, thus only small changes needed to be applied to work with 6 thrusters. The two other algorithms, based on the Simplex and Karmarkar method, were completely developed from scratch. To analyze their performance several tests were executed. This includes unit tests on a simple computer hardware with different input, Monte Carlo simulations on a cluster to test if the algorithms are suitable for MTG orbital manoeuvres and the application to 12 thrusters, mounted on a generic satellite to generate torques and forces at the same time for 6 degrees of freedom manoeuvres. For each thruster configuration the worst case outputs are shown in so called minimum control authority plots. The performance analysis consists of the maximum and average deviation between requested and generated torque/force, the average computed thruster on-times, the algorithms computation(running) time and iteration steps. For MTG the test results clearly confirm that the usage of 6 thrusters leads to more accurate generated torques and better control authority, than using only 4 thrusters. The Simplex method stands out here in particular, showing excellence performance regarding torque precision. Nevertheless the accuracy goes at the expense of computation effort. While the Pseudoinverse method is very fast and needs only one iteration step, the Simplex is half a magnitude, the Karmarkar one magnitude slower. But the latter lead to lower thruster on-times in terms of firing duration and thus fuel consumption is reduced. Also it is shown that Simplex and Karmarkar can control 12 thrusters at the same time to generate torques and forces, which proves their scalability to any thruster distribution. In the end it comes to the question whether generating a more accurate torque/force or the computational effort, which is strongly hardware dependent, is more important. A decision which depends on the mission’s objective. This paper shows that all three implemented algorithms are able to handle attitude control in the MTG backup scenario and beyond.

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