Conclusions. The sensitivity and positive predictive value are generally more concerned than the specificity and negative predictive value in assessing and adjusting publication bias in meta-analyses. In this sense, Egger's regression can be recommended for its high sensitivity, while any positive result from Tang's method would suggest a probability of bias that should be taken seriously. Given the different patterns of the accuracy with the OR and the P1-P2 combination, a combination of Egger's regression and Tang's regression would be advisable. Further studies are needed to study the accuracy of methods used in combination. / Due to sampling error and true heterogeneity, a single study cannot provide a comprehensive picture and a precise estimate of, say the effectiveness of a treatment. Systematic reviews that identify and integrate relevant studies have become the most important scientific, quantitative method to summarize scientific research. Meta-analysis is the statistical method used in systematic reviews to combine results from individual studies. / However, due to selective submission and publication, not all relevant studies conducted, especially those unpublished studies with an insignificant negative result, are easily accessible to those who conduct reviews. As a result, the truth, say, the effect of a treatment, would be overestimated. This phenomenon is known as publication bias. A few methods for detecting the bias have been developed and used in meta-analyses. Although their accuracy has been studied, some important issues remain to be answered, such as when would a method be good enough for practical use and is it similarly good for different definitions of the odds ratio? / Methods. We conducted a simulation study to examine the accuracy of four commonly used bias-detection methods with various ORs and P1-P2 combinations. In a simulation study, the true bias status can be predetermined and thus be compared with the results of the bias-detection methods. The four methods are Egger's regression, funnel plot regression, rank correlation regression, and Tang's regression. Realistic sample size was used for simulating individual studies and the numbers of studies in a meta-analysis was also varied. Both the sensitivity and specificity are examined against the magnitude of the OR and the P1-P 2 combination to identify the ORs and P1-P 2 combinations for which a method is sufficiently accurate. Predictive values are also examined for the same reason and in the same manner. / Results. The sensitivity and positive predictive value are generally low and in particular when the OR is close to one for which publication bias is of a particular concern. Egger's regression has the highest sensitivity among the four, in particular when the OR is neither close to one nor exceptionally large or small. Due to the relatively lower specificity, the positive predictive value of Egger's regression is not as high as that for Tang's regression and funnel plot regression. Tang's regression and funnel plot regression are very similar in sensitivity, specificity and predictive values, with the former being slightly better. Rank correlation seems the least accurate method overall. Tang's regression has in general the highest positive predictive value among the four methods in particular when the OR is below one. / Chung Chi-keung. / "June 2006." / Adviser: Tang Jin Ling. / Source: Dissertation Abstracts International, Volume: 68-03, Section: B, page: 1588. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2006. / Includes bibliographical references (p. 116-124). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstracts in English and Chinese. / School code: 1307.

Experimental study of the designer plays a critical role in design research. However laboratory based study is often poorly compared and contrasted to practice, leading to a lack of uptake and subsequent research impact. The importance of addressing this issue is highlighted by its significant influence on design research and many related fields. As such the main aim of this work is to improve empirical design research by characterising the relationship between practice and laboratory-based studies for critical design situations. A review of the state of the art methods in design research and key related fields is reported. This highlights the importance and commonality of a set or core issues connected to the failure to effectively link study of practice and study in the laboratory. Further to this a technical review and scoping was carried out to establish the most efective capture strategy to be used when studying the designer empirically. Subsequently three studies are reported, forming a three point comparison between practice the laboratory (with student practitioners) and an intermediary case (a laboratory with practitioners) . Results from these studies contextualise the critical situations in practice and develop a detailed multi-level comparison between practice and the laboratory which was then validated with respect to a number of existing studies. The primary contribution of this thesis is the development of a detailed multi-level relationship between practice and the laboratory for critical design situations: information seeking, ideation and design review. The second key contribution is the development of a generic method for the empirical study of designers in varying contexts - allowing researchers to build on this work and more effectively link diverse studies together. The final key contribution of this work is the identification of a number of core methodological issues and mitigating techniques affecting both design research and its related fields.

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This dissertation addresses two problems with advanced academic writing pedagogy. First, doctoral students must participate in academic discourse communities, yet they report being underprepared to do so (Boquet et al., 2015; Caplan & Cox, 2016). Second, studies (e.g., Curry & Lillis, 2004; Matsuda & Tardy, 2007; Tardy & Matsuda, 2009) suggest that L1 and L2 voices are not well integrated in the institution and that this lack of integration systemically privileges the dominant culture. The purpose of this research is to investigate the role relationships play in helping culturally and linguistically diverse doctoral students negotiate and acquire advanced academic discourse. I pose the overarching research question: Given a discipline-specific writing center for graduate students in a College of Education, what role does interaction play in helping students to participate in academic conversations? The two papers in this collection employ qualitative classification and discourse analysis to investigate writing-related interactions among peers. Data include audio-recorded writing consultations and interviews, post-session reports, field notes, and artifacts. Taken together, findings from this research highlight the role interaction can play in writing support, development, and research. This research has implications for developing writing pedagogy and support programs to facilitate productive academic socialization. In response, the researcher calls for more robust academic writing support in order to improve access and resources for diverse student populations and decrease attrition and time to degree for all students.

This study explores human-robot interaction during a 16-hour high-fidelity Urban Search and Rescue (USAR) disaster response drill with teleoperated robots. Situation awareness and team interaction were examined using communication analysis. Operators (n=5) sought assistance from team members to compensate for difficulties building or maintaining situation awareness. Operator-team member communication focused on relating what was seen through the robot's eye view with prior knowledge and planning search strategies. Results suggest operators need a new cognitive mental model to filter and comprehend data provided by the robot, and that robot-assisted search is a team task rather than an individual one. USAR technical search teams need a new shared mental model of robot-assisted search in order to coordinate activities effectively.

Improving the quality use of medicines (QUM) among seniors, particularly those using multiple medicines, is a national priority. The National Prescribing Service??s Seniors QUM Program was developed in collaboration with consumers to address seniors?? medicines information needs. Seniors are trained as peer educators to convey QUM messages to other seniors in a single group session. However, there is a dearth of research assessing peer education for seniors about medicines, and little understanding of what peer educators do in practice. This research investigated how peer educators empower seniors toward the quality use of their medicines. A participatory action research inquiry was undertaken nationally with organisational leaders and locally with peer educators. The design was a nested case study with multiple sites, where the Seniors Program was the overarching case containing eight disparate local sites. The participatory inquiry engaged peer educators from each local site. Qualitative data were collected through participant observation and interviews. Data were analysed using grounded theory methods and findings were triangulated with other data sources. Peer educators demonstrated five main functions in the program ?? one primary function within QUM sessions and four support functions outside of sessions. The primary function of facilitating peer learning comprised 10 elements. A model depicts these elements in the context of varying session conditions and consequences. Educators?? lived experience as seniors and lay persons was an overarching contributor to peer learning, used strategically through storytelling to assist other elements. Sharing QUM outside of sessions occurred frequently, but requires development to reach isolated seniors. Peer educators exceeded expectations in getting QUM messages to seniors, applying unique skills to the information exchange within sessions. Their status as lay persons tackling the complex topic of QUM reflected an understanding of the disempowerment seniors may feel when seeking information about medicines. Peer educators?? ability to model an active partner role by applying their lived experience through storytelling in an interactive, mutually sharing session challenged seniors to rethink their medicines management and interactions with health professionals. As the population ages and medicines use increases, understanding and using seniors effectively as educators has great potential.

A critical task in the formation of any political group is the determination and articulation of group identity, purpose and goals. In holding that identity is impervious to capture, much poststructuralist thought has little to contribute to an understanding of the precise processes and ongoing tensions involved in such drives for representation. The essentialism debate in feminist theory, for instance, has been primarily concerned with determining which conceptualisation of women's subjectivity will best facilitate feminism's political goals. However, under the influential feminist deconstructive perspective, a dilemma emerges regarding how an anti-essentialist notion of femininity might be reconciled with the essentialism required for a distinctly feminist voice. Alternatively, post-Lacanian psychoanalysis views subjectivity as an effect of fundamentally irresolvable antagonisms in language, allowing the emphasis to shift from the (attempted) reconciliation of irresolvable tensions to the identification of mechanisms that work to conceal those tensions, thereby permitting a sense of subjectivity to be articulated. This thesis explores the methodological implications of these theoretical debates, examining how the psychoanalytic line of questioning might be used to analyse feminist identity in an empirical setting. Research was conducted with the Women's Resource Centre (WRC) based in Auckland, New Zealand, an organisation originally established to provide feminist theology resources to women undergoing theological education. Using a conversational methodology and the observation of material expressions of identity, the research attempts to view the Centre's identity 'askew.' In doing so, it considers the creative yet eventually regressive impact of the postmodern privileging of difference and multiplicity on the feminist identity of the Centre. Referring specifically to the changing expression of the Centre's identity (in promotional material, funding applications and the WRC Story), the thesis traces the effects of ideological tension (in incorporating more inclusive notions of justice with feminist politics) and organisational change (dispersion of the original community, high staff turnover, shift in organisational culture, funding difficulties). Wider implications of the research for voluntary and feminist organisations are indicated, along with an evaluation of post-Lacanian psychoanalysis for the empirical study of identity and for the overarching theoretical concerns of the thesis.

This study identifies informal networks as the most accepted method of sharing information. Enhancing service delivery is shown as being a key trigger of coordination while rigid funding approaches are perceived to be a major inhibitor. Organisational type, position, practice approaches and location are shown to influence people's perception of coordination.

PROBLEM DISCUSSION: Vaggeryd is a small municipality Småland. In addition to its strategic position along the main traffic route E4, Vaggeryd is very interesting also because of its advanced view on growing of the business sector, in both short and long-term per- spective. To meet that goal the municipality of Vaggeryd started to invest in “Egenföretagareutbildningen” EFU in cooperation with Jönköping International Business School (JIBS). The main idea is that students attend the courses that are held by JIBS and during their studies start their own business in a local business incubator called Fenix. PURPOSE: To host such education requires a huge amount of energy and resources from the municipality, which consequently would like to get answers to questions like “Is it worth investing in the education?” or “What are the results of such education?” The aim of this paper is to give the answers to those crucial questions though I believe that the time that has passed from the beginning of the education is too short and that the number of the students was not large enough to get definitive answers. This paper concentrates on a narrow part of the qualitative research methods – an inter- view. It is divided into two parts, a theoretical part and the empirical findings. FINDINGS: The research showed that six students out of a total of ten from generation 2005 started a new venture, three will take over a family business, and one has not decided to start a business yet. Of six students in generation 2003 four have started a business and one of them finished in bankruptcy, one plans to start a business in the future and one does not have a good business idea. RECOMMENDATIONS: Answers that the interviews returned gave interesting sugges- tions to both the municipality of Vaggeryd and JIBS about how to improve EFU. I would emphasise two, I believe, the most important recommendations. First municipality has to attract neighbouring municipalities in the EFU project. In addition, a greater effort should be made to help students build a spider’s web of business contacts.

Although medical advances have improved prognosis for children with cystic fibrosis (CF) and congenital heart disease (CHD), these youth experience poor psycho - social health. Embedded within the Medical Research Council’s framework, the purpose of this Dissertation was to a) examine how CF and CHD children experience physical activity, b) explore parents’ perceptions toward their child’s activity, c) develop a theory of physical activity in childhood chronic diseases, d) develop a physical activity counselling program for youth with CF and their parents, and e) evaluate the program impact on quality of life and physical activity. Study One explored how 14 CF youth experience physical activity. Active and inactive youth were characterized by different experiences, such as a sense of hope or despair. Given the burden of treatment and the fatal nature of the disease, youth negotiated temporal barriers to activity. Study Two explored perceptions toward activity among 29 CF and CHD parents. Parents discussed the benefits and barriers associated with physical activity for both child and self, and underscored the importance of role modeling. By adopting a Grounded Theory approach, the theoretical constructs from Study One and Two were crystallized to develop a theory of physical activity in youth with CF and CHD. This theory was used to develop “CF Chatters:” A Six Week Physical Activity Counselling Program for Youth with CF and their Parents, and the intervention employed behavioural self regulation ii skills. In Study Three, four case families in the CF clinic at the Hospital for Sick Children participated in CF Chatters. Improvements were noted in quality of life and physical activity, and participants described the program as convenient and relevant to their activity concerns. CF Chatters afforded therapeutic benefits to participants. By employing an eclectic qualitative approach, this Doctoral Program has made theoretical and practical contributions toward our understanding of how physical activity is experienced among children living with CF/CHD. The findings support the use of behavioural counselling as an effective and feasible modality for enhancing quality of life and physical activity. This Dissertation calls on clinicians to attend to the activity needs of chronically ill Canadian youth.