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Effects of genotype and RNA expression on activity of cytochrome P450 2D6 : a highly polymorphic drug metabolizing enzyme /McConnachie, Lisa A. January 2002 (has links)
Thesis (Ph. D.)--University of Washington, 2002. / Vita. Includes bibliographical references (leaves 133-146).
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Exkursioner i gymnasieskolan : Lärande, motivation och platsSchmidinger, Helen January 2015 (has links)
The present licentiate thesis comprises a review of Swedish and Anglo-Saxon literature on excursions and their history, followed by a study on three one-day excursions and two neighbourhood excursions, conducted by pupils at upper secondary school. The primary purpose of the thesis was to highlight the development of excursion procedures, aiming at increasing the interest of the pupils, improving their inner motivation, but also to develop the learning process. Thus, the work also attempted to identify learning models and excursion methods, furnishing pupils with a positive attitude during excursions and field studies. Article no 1 consists of a survey of Swedish (particularly in Geographical Notices) and Anglo-Saxon literature, describing and discussing how the excursion procedures have been developed, influenced, and designed. Excursions became a practiced teaching method at the beginning of the last century. The urbanization and instigation of a public school are described as incitements for arranging excursions. British as well as Swedish teaching authorities emphasized excursions in school activities in different curricula or school documents. The present study shows that arranging excursions and other activities in the field was in the interests of the teaching authorities and a number of different society instances. Excursion methods and their extent and incorporation into the school activities have been amply discussed in the excursion literature. Qualitative interviews with 50 pupils from five upper secondary schools were conducted after excursions. Observations were carried out during four of these excursions. Article II comprises one-day excursions in geography or biology, conducted by pupils in the social and natural science programs at three upper secondary schools. The methods applied in this study were group interviews and observations during two of the excursions. Two neighbourhood excursions in geography and science, performed by two upper secondary schools, were investigated, and form the foundation for article II. The neighbourhood excursions were examined by observations, 25 individual interviews, and a smaller questionnaire. The interviews generated information about how pupils perceive, experience, and interpret the applied excursion methods. Pupils have in interviews and in their questionnaire answers reported their motivation, which ranged from non-existent to a deep inner motivation. Preparations were identified as a key factor for pupils as well as teachers. The observations yielded knowledge about the focus of pupils, their attitudes and concentration level, and also how they use digital media in the field. Furthermore, the relevance of location, along with pupils’ comprehensions and experiences, created an applicable backdrop for future excursions. Careful selection of excursion locations, where pupils are able to discern correlations, was identified as important to their capability of interpreting their observations, which they afterwards might be able to transform into knowledge, inner motivation, or even flow.
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Augalinių preparatų rinka Lietuvoje / Market of herbal preparations in LithuaniaSteponavičiūtė-Pučinskienė, Laima 15 June 2006 (has links)
According to data of research company „IMS Health“ the pharmacy market in Lithuania increases year by year, and sales of non-prescribed medicine increase significantly. A part of those sales is comprised of herbal medicine preparations. Analysis of competitive environment, analysis of available preparations portfolio and possibilities of the company‘s development are compulsory seeking to stay competitive. During the last years we observed an increasing interest of consumers in herbal medicine preparations, therefore, the topic chosen is relevant for the Master‘s Degree thesis.
Aim of the study: to evaluate possibilities of development of „Bionorica AG“ company on Lithuanian market.
Objectives: Review of market of herbal preparations, evaluation of external environment, analysis of portfolio of the company‘s preparations, possibilities and analysis of the company‘s development on the market.
Methods – model of M. Porter, with the help of which competitive analysis was performed. Survey of drugstores. Questionnaire data of surveys were entered, processed and analyzed with the use of statistics data analysis program SPSS. Analysis of the products‘ portfolio was performed with the use of matrix model of Boston consulting group (BCG). Possibilities of the company‘s development are analyzed in the paper with the use of forecasting method - trend model.
Results:
Many large companies, which follow each others‘ actions in order to know the means that are necesary to be assumed... [to full text]
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Kinetic and mechanistic study of Lilestralis, a synthetic muguet fragrance moleculeScott, Laura-Marie January 2011 (has links)
In the multi-step synthesis of Lilestralis, a synthetic muguet fragrance, the kinetics and mechanism of the formation of 3-(3-t-butylphenyl)-2-methylpropan-1-ol (m-LOL) and 4-(3-t-butylphenyl)-2-methylpropan-1-ol (p-LOL) from 2-methyl-3-phenylpropan-1-ol (MPP) and isobutylene using concentrated liquid phosphoric acid as a catalyst was investigated. By-products that include phosphate esters of MPP, m-LOL and p-LOL and oligomers of isobutylene were produced during this reaction and their role within the kinetics and mechanism was also investigated. When crystalline phosphoric acid is dissolved in water, it can form equilibrium polyphosphate mixtures at high acid concentrations. The phosphate species have the general formula Hn+2PnO3n+1 and consist of species such as orthophosphoric acid (H3PO4), pyrophosphoric acid (H4P2O7) and triphosphoric acid (H5P3010). The presence of polyphosphate within liquid phosphoric acid solutions used in this study was investigated using 31P NMR. To investigate the influence of water on the reaction, a number of experiments were performed using 1,4-dioxane as a solvent. This was chosen as the boiling points and density are similar to water, although it is classified as an aprotic solvent. Phosphate esters of MPP, m-LOL and p-LOL are produced as by-products and can potentially undergo hydrolysis when water is present, therefore reactions using aqueous phosphoric acid solutions may not give a true reflection of the concentration of phosphate esters produced. The use of heterogeneous catalysts was also investigated in order to improve yield and selectivity for p-LOL and m-LOL. These include acid catalysts such as solid phosphoric acid supported on Kieselguhr (SPA), sulphated zirconia and ultra stable zeolite-Y (H-USY).
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Anti-obesity effects of green tea EGCG, orange peel extract, black tea extract and caffeine in mice fed on a high-fat dietHuang, Yuwen. January 2007 (has links)
Thesis (M.S.)--Rutgers University, 2007. / "Graduate Program in Food Science." Includes bibliographical references (p. 74-79).
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Chiral separation of amines by non-aqueous capillary electrophoresis using low molecular weight selectors /Hedeland, Ylva, January 2006 (has links)
Diss. (sammanfattning) Uppsala : Uppsala universitet, 2006. / Härtill 5 uppsatser.
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Drug dissolution under physiologically relevant conditions in vitro and in vivo /Persson, Eva, January 2006 (has links)
Diss. (sammanfattning) Uppsala : Uppsala universitet, 2006. / Härtill 4 uppsatser.
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Delivery of a coated bioactive from a rumen controlled-release deviceSyzov, Vladyslav. January 2008 (has links)
Thesis (M.E.)--University of Waikato, 2008. / Title from PDF cover (viewed September 18, 2008) Includes bibliographical references (p. 66-70)
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Patterns of drug prescription and their effect upon cost of drugs in a community hospital submitted ... in partial fulfillment ... Master of Hospital Administration /Warden, Gail L. January 1962 (has links)
Thesis (M.H.A.)--University of Michigan, 1962.
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UTI antibiotics : mechanism of transport and in vivo interaction with cranberry juice /Li, Meng. January 2007 (has links)
Thesis (Ph. D.)--University of Washington, 2007. / Vita. Includes bibliographical references (leaves 186-197).
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