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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 191 to 200 of 412 (0.007 seconds)| 191 |
Characterization of Myopathy in Mice Overexpressing Androgen Receptor in Skeletal MuscleMusa, Mutaz 27 July 2010 (has links)
Although androgens are known to exert anabolic effects in skeletal muscle,
overexpression of androgen receptor (AR) selectively in this tissue causes androgen dependent motor deficits and muscular atrophy. The cellular and subcellular changes
underlying this phenotype are unknown. Therefore, this study aimed to elucidate the
ultrastructural and histologic changes accompanying myopathy and to determine the
importance of androgens and overexpression level for myopathic features. Transmission
electron microscopy revealed augmented mitochondrial content and reduced myofibril
width in androgen exposed transgenics. Additionally, male transgenics demonstrated
increased glycogen content. Histochemical analyses confirmed sex-specific changes in
glycogen content and revealed a surprising loss in the proportion of oxidative fibers in
symptomatic animals. However, increased mitochondrial content was confirmed by the
presence of ragged red fibers. Overexpression of AR in muscle fiber results in mitochondrial pathology and dysregulation of glycogen metabolism, possibly reflecting
normal but exaggerated function of androgens in skeletal muscle fibers.
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| 192 |
Walking (or Jogging) the Talk: Healthcare Professionals' Experiences of Taking Care of their Own HealthMoore, Jennifer Bronwen 01 January 2011 (has links)
Many healthcare providers are at risk of compassion fatigue and burnout from prolonged occupational stress, which can adversely affect workers, patients, and the healthcare system. This qualitative research project inquired into eight female healthcare providers’ experiences of sustaining their own wellbeing. Participants (27 to 60 years old) engaged in semi-structured interviews and participant observation of a self-care activity. Themes were found relating to the variety of self-care strategies used, challenges and supports in the work context, and the important role of authenticity in health promotion practice. Self-care strategies included: social support, pacing, taking breaks, exercise, nutrition, emotional self-care, adapting self-care routines over time, goal setting and prioritization. Supports to wellbeing included: flexible scheduling, taking personal responsibility for wellness, workplace wellness programs, and positive relationships with supervisors, colleagues, friends and family. This arts-informed research project is presented in graphic novel form to enhance its accessibility.
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| 193 |
Care Transitions from the Patient Perspective: A Focus on the Communication of Discharge InstructionsQuigley, Laura 13 January 2011 (has links)
Communication of hospital discharge instructions between patient and provider is an important component of hospital discharge to ensure that patients have the information they need to manage their post-acute care. Patient perception of this interaction is a key indicator of the quality of services provided. This study examined whether there is a correlation between hospital continuity and transition scores (a measure of patient perceptions of hospital discharge instructions) and hospital readmissions in Ontario.
The final regression model for the outcome of all medical readmissions within three days of hospital discharge, showed a significant positive relationship (coefficient=0.0090, p=0.011). The estimate was smaller and not significant once the data was restricted to only community hospitals located outside of Toronto (coefficient=0.0085, p=0.060), and when restricted to urban community hospitals outside of Toronto (coefficient=0.0041, p=0.384). For the outcome of specific medical readmissions within 28 days of hospital discharge, no statistically significant relationship was found.
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| 194 |
Creative Engagement Through the Arts as Health Care for Older People: Potential and Problems ProvokedHouser, Ezra 29 November 2011 (has links)
Programs that use the arts to engage older people promote health, foster community, and give voice and legacy to participants. Creative practice in health care settings facilitates emotional, mental, and physical wellness for participants and staff, while improving the culture of care.
Yet there is resistance to arts-in-medicine as a legitimate tool of health care. The predominant biomedical paradigm privileges quantitative assessment methods over qualitative studies which may accept anecdotal, arts-informed, or “common sense” evidence.
Successful creative programs face challenges translating their benefits when evaluated inappropriately.
This arts-informed inquiry uses creative writing to address multiple dimensions of knowing, integrating autoethnographical insights from work as a caregiver, artist, educator, and administrator of collaborative art. Serendipity and imagination in research were employed to explore how collaborating artists can facilitate creative engagement for elders, embodying preventative, community-based medicine to successfully address and transform myriad challenges and opportunities as the population continues to age.
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| 195 |
No Fault Found Reporting and its Relation to Human Factors Related Design Faults of Medical DevicesFlewwelling, Christopher John 22 November 2012 (has links)
This research used human factors methods to investigate the relationship between no fault found (NFF) incident frequency and device usability. NFF reporting occurs when a medical device sent for repair is found to be operating normally. NFF incidents are one of the most recurrent failure modes, and therefore have considerable impact on cost, dependability and safety. An analysis of medical equipment maintenance data was conducted and six devices with a high NFF reporting frequency were identified. Semi-structured interviews and heuristics evaluations revealed that usability issues likely caused many of the NFF incidents. Other factors suspected to contribute to increased NFF reporting include accessory issues, intermittent faults and environmental issues. Finally, in order to validate the results, usability testing was conducted on three of the devices. 23 usability-related design flaws were identified. Therefore devices containing latent usability-related design flaws can be identified through analysis of medical equipment maintenance data.
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| 196 |
Examination of the Association between Voluntary Accreditation and Resident Safety in Ontario Long Term Care HomesMcDonald, Shawna 18 March 2013 (has links)
Objective: determine whether accreditation through Accreditation Canada is associated with more favorable resident safety in Ontario LTC homes and which facility characteristics are predictive of accreditation. Methods: logistic regression was used to determine predictors of accreditation. To examine the association between accreditation and safety, safety was operationalized as five MDS-RAI quality indicators: prevalence of falls, restraints, catheters, pressure ulcers, and infections. Separate multivariable models were developed for each indicator. Results: the odds of accreditation were approximately six times smaller for municipal (p < 0.001) and non-profit facilities (p < 0.001) relative to for-profits; three times greater for chains relative to non-chains (p < 0.001); and twice as large for urban relative to rural facilities (p = 0.04). Of the five quality indicators examined, only one (falls) was associated with accreditation. After adjusting for confounders, accredited homes were estimated to have 8% lower fall rates than non-accredited homes (p = 0.01).
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| 197 |
Characterization of Myopathy in Mice Overexpressing Androgen Receptor in Skeletal MuscleMusa, Mutaz 27 July 2010 (has links)
Although androgens are known to exert anabolic effects in skeletal muscle,
overexpression of androgen receptor (AR) selectively in this tissue causes androgen dependent motor deficits and muscular atrophy. The cellular and subcellular changes
underlying this phenotype are unknown. Therefore, this study aimed to elucidate the
ultrastructural and histologic changes accompanying myopathy and to determine the
importance of androgens and overexpression level for myopathic features. Transmission
electron microscopy revealed augmented mitochondrial content and reduced myofibril
width in androgen exposed transgenics. Additionally, male transgenics demonstrated
increased glycogen content. Histochemical analyses confirmed sex-specific changes in
glycogen content and revealed a surprising loss in the proportion of oxidative fibers in
symptomatic animals. However, increased mitochondrial content was confirmed by the
presence of ragged red fibers. Overexpression of AR in muscle fiber results in mitochondrial pathology and dysregulation of glycogen metabolism, possibly reflecting
normal but exaggerated function of androgens in skeletal muscle fibers.
|
| 198 |
Walking (or Jogging) the Talk: Healthcare Professionals' Experiences of Taking Care of their Own HealthMoore, Jennifer Bronwen 01 January 2011 (has links)
Many healthcare providers are at risk of compassion fatigue and burnout from prolonged occupational stress, which can adversely affect workers, patients, and the healthcare system. This qualitative research project inquired into eight female healthcare providers’ experiences of sustaining their own wellbeing. Participants (27 to 60 years old) engaged in semi-structured interviews and participant observation of a self-care activity. Themes were found relating to the variety of self-care strategies used, challenges and supports in the work context, and the important role of authenticity in health promotion practice. Self-care strategies included: social support, pacing, taking breaks, exercise, nutrition, emotional self-care, adapting self-care routines over time, goal setting and prioritization. Supports to wellbeing included: flexible scheduling, taking personal responsibility for wellness, workplace wellness programs, and positive relationships with supervisors, colleagues, friends and family. This arts-informed research project is presented in graphic novel form to enhance its accessibility.
|
| 199 |
Care Transitions from the Patient Perspective: A Focus on the Communication of Discharge InstructionsQuigley, Laura 13 January 2011 (has links)
Communication of hospital discharge instructions between patient and provider is an important component of hospital discharge to ensure that patients have the information they need to manage their post-acute care. Patient perception of this interaction is a key indicator of the quality of services provided. This study examined whether there is a correlation between hospital continuity and transition scores (a measure of patient perceptions of hospital discharge instructions) and hospital readmissions in Ontario.
The final regression model for the outcome of all medical readmissions within three days of hospital discharge, showed a significant positive relationship (coefficient=0.0090, p=0.011). The estimate was smaller and not significant once the data was restricted to only community hospitals located outside of Toronto (coefficient=0.0085, p=0.060), and when restricted to urban community hospitals outside of Toronto (coefficient=0.0041, p=0.384). For the outcome of specific medical readmissions within 28 days of hospital discharge, no statistically significant relationship was found.
|
| 200 |
Creative Engagement Through the Arts as Health Care for Older People: Potential and Problems ProvokedHouser, Ezra 29 November 2011 (has links)
Programs that use the arts to engage older people promote health, foster community, and give voice and legacy to participants. Creative practice in health care settings facilitates emotional, mental, and physical wellness for participants and staff, while improving the culture of care.
Yet there is resistance to arts-in-medicine as a legitimate tool of health care. The predominant biomedical paradigm privileges quantitative assessment methods over qualitative studies which may accept anecdotal, arts-informed, or “common sense” evidence.
Successful creative programs face challenges translating their benefits when evaluated inappropriately.
This arts-informed inquiry uses creative writing to address multiple dimensions of knowing, integrating autoethnographical insights from work as a caregiver, artist, educator, and administrator of collaborative art. Serendipity and imagination in research were employed to explore how collaborating artists can facilitate creative engagement for elders, embodying preventative, community-based medicine to successfully address and transform myriad challenges and opportunities as the population continues to age.
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